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Systematic analysis of mucosal‐associated invariant T cells in haematological malignancies Scand. J. Immunol. (IF 3.7) Pub Date : 2024-03-06 Barbora Bacova, Jakub Cierny, Lucia Nemcekova, Jitka Smetanova/Brozova, Jan Novak
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Blood defense system – Proposal for a new concept of an immune system against blood borne pathogens comprising the liver, spleen and bone marrow Scand. J. Immunol. (IF 3.7) Pub Date : 2024-03-05 Makoto Kashimura
Blood‐borne pathogen (BBP) infections can rapidly progress to life‐threatening sepsis and must therefore be promptly eliminated by the host's immune system. Intravascular macrophages of the liver sinusoid, splenic marginal zone and red pulp and perisinusoidal macrophage protrusions in the bone marrow (BM) directly phagocytose BBPs in the blood as an innate immune response. The liver, spleen and BM
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Changes in serum immunoglobulin G glycosylation patterns for antiphospholipid syndrome patients with lectin microarray Scand. J. Immunol. (IF 3.7) Pub Date : 2024-03-05 Yifei Wang, Siting Li, Jingjing Meng, Rui Yu, Qian Wang, Xinping Tian, Mengtao Li, Xiaofeng Zeng, Jiulang Zhao, Chaojun Hu
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The presence of autoantibodies as a potential prognostic biomarker for breast cancer Scand. J. Immunol. (IF 3.7) Pub Date : 2024-02-29 Libo Ouyang, Keying Jing, Chunkai Zhu, Rong Wang, Peiming Zheng
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Oxidized low-density lipoproteins impair the pro-atherosclerotic effect of granulocyte-macrophage-colony-stimulating factor-producing T helper cells on macrophages Scand. J. Immunol. (IF 3.7) Pub Date : 2024-02-14 Xiaofang Xiong, Zheng Yan, Long Yan, Xuexue Yang, Dongsheng Li, Guizhen Lin
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Markedly upregulated serum semaphorin 4A as a novel activity marker of myasthenia gravis Scand. J. Immunol. (IF 3.7) Pub Date : 2024-02-14 Akiyuki Uzawa, Manato Yasuda, Hiroyuki Akamine, Yosuke Onishi, Hideo Handa, Etsuko Ogaya, Yukiko Ozawa, Hiroki Masuda, Masahiro Mori, Satoshi Kuwabara
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The role of bile acid receptor TGR5 in regulating inflammatory signalling Scand. J. Immunol. (IF 3.7) Pub Date : 2024-02-02 Daijiao Ye, Jiayao He, Xiaofei He
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Interaction of T-cell-specific adapter protein with Src- and Tec-family kinases Scand. J. Immunol. (IF 3.7) Pub Date : 2024-01-28 Zsuzsa Huszenicza, Brian C. Gilmour, Lise Koll, Hanna Kjelstrup, Hanna Chan, Vibeke Sundvold, Stine Granum, Anne Spurkland
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Haematopoietic innate interleukin 17A production drives immunopathology in female mouse genital Chlamydia muridarum infection Scand. J. Immunol. (IF 3.7) Pub Date : 2024-01-21 Charles W. Armitage, Emily R. Bryan, Logan Trim, Ella Palframan, Lucas Wager, Kenneth W. Beagley, Alison J. Carey
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Unlocking PD-1 antibody resistance: The MUC1 DNA vaccine augments CD8+ T cell infiltration and attenuates tumour suppression Scand. J. Immunol. (IF 3.7) Pub Date : 2024-01-19 Xiaoqin Wang, Yinsha Miao, Jinghui Shen, Dandan Li, Xinyue Deng, Chengcheng Yang, Yanhong Ji, ZhiJun Dai, Yunfeng Ma
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The role of hormones in ILC2-driven allergic airway inflammation Scand. J. Immunol. (IF 3.7) Pub Date : 2024-01-19 Zhongling Dai, Zhande Gong, Cui Wang, WeiXiang Long, Duo Liu, Haijun Zhang, Aihua Lei
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Concerns about the histological assessment in a mouse model of human celiac disease Scand. J. Immunol. (IF 3.7) Pub Date : 2024-01-16 Tobias L. Freitag, Leif C. Andersson, Anja Kipar
Commentary on: Abadie V et al. IL-15, gluten and HLA-DQ8 drive tissue destruction in coeliac disease. Nature. 2020; 578: 600-604. Celiac disease (CD) is a common immune-mediated, gluten-sensitive enteropathy that develops in human leukocyte antigen (HLA)-DQ2 or HLA-DQ8 allele carriers due to the dysregulation of gluten-specific T helper cells. Although ingested gluten from cereals was identified as
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Predictive model for CAR-T cell therapy success in patients with relapsed/refractory B-cell acute lymphoblastic leukaemia Scand. J. Immunol. (IF 3.7) Pub Date : 2024-01-16 Lianfang Pu, Huiping Wang, Fan Wu, Furun An, Hao Xiao, Yangyang Wang, Xue Liang, Zhimin Zhai
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Exosomal miR-126-3p: Potential protection against vascular damage by regulating the SLC7A5/mTOR Signalling pathway in human umbilical vein endothelial cells Scand. J. Immunol. (IF 3.7) Pub Date : 2024-01-16 Ke Zhu, Chen Liu, Xiaofang Guo, Xuting Zhang, Jiaxin Xie, Songmiao Xie, Qing Qi, Bin Yang
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Antibody responses to immunoevasion proteins BBK32 and OspE constitute part of the serological footprint in neuroborreliosis but are insufficient to prevent the disease Scand. J. Immunol. (IF 3.7) Pub Date : 2024-01-11 Vinaya Dulipati, Juha Kotimaa, Mikel Rezola, Mikko Kontiainen, Hanna Jarva, Dag Nyman, Seppo Meri
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Activation of neutrophils excels the therapeutic potential of Mycobacterium indicus pranii and heat-induced promastigotes against antimony-resistant Leishmania donovani infection Scand. J. Immunol. (IF 3.7) Pub Date : 2024-01-08 Kamalika Roy, Sanhita Ghosh, Mintu Karan, Suman Karmakar, Supriya Nath, Bedanta Das, Sharmistha Paul, Pritam Mandal, Monalisa Ray, Mousumi Das, Soumyadip Mukherjee, Somaditya Dey, Chiranjib Pal
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Correction to “Research progress on intestinal tissue-resident memory T cells in inflammatory bowel disease” Scand. J. Immunol. (IF 3.7) Pub Date : 2024-01-04
Chen, K, Gu, X, Yang, S, et al. Research progress on intestinal tissue-resident memory T cells in inflammatory bowel disease. Scand J Immunol. 2023; 98:e13332. doi:10.1111/sji.13332 In the article entitled “Research progress on intestinal tissue-resident memory T cells in inflammatory bowel disease” that was previously published in Volume 98 Issue 6 of Scandinavian Journal of Immunology, an extra affiliation
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MASP-2 deficiency does not prevent the progression of diabetic kidney disease in a mouse model of type 1 diabetes Scand. J. Immunol. (IF 3.7) Pub Date : 2023-12-25 Holt Charlotte Brinck, Halkjær Lene, Dudler Tom, Schwaeble Wilhelm, Hansen Troels Krarup, Thiel Steffen, Østergaard Jakob Appel
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From hepatitis B virus infection to acute-on-chronic liver failure: The dynamic role of hepatic macrophages Scand. J. Immunol. (IF 3.7) Pub Date : 2023-12-19 Yu Zhang, Dongsheng Wu, Xiaoling Tian, Bin Chen
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Unveiling the intricacies of COVID-19: Autoimmunity, multi-organ manifestations and the role of autoantibodies Scand. J. Immunol. (IF 3.7) Pub Date : 2023-12-10 Zetao Ding, Xingyi Wei, Haoyu Pan, Hui Shi, Yue Shi
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Gut bacteria at 6 months of age are associated with immune cell status in 1-year-old children Scand. J. Immunol. (IF 3.7) Pub Date : 2023-12-07 Morten Nilsen, Unni Cecilie Nygaard, Petter Brodin, Karin Cecilie Lødrup Carlsen, Cecilie Fredheim, Guttorm Haugen, Gunilla Hedlin, Christine Monceyron Jonassen, Unni Lise Albertsdottir Jonsmoen, Tadepally Lakshmikanth, Björn Nordlund, Axel Olin, Eva Maria Rehbinder, Håvard O. Skjerven, Lars Snipen, Anne Cathrine Staff, Cilla Söderhäll, Riyas Vettukattil, Knut Rudi
Age-related gut bacterial changes during infancy have been widely studied, but it remains still unknown how these changes are associated with immune cell composition. This study's aim was to explore if the temporal development of gut bacteria during infancy prospectively affects immune cell composition. Faecal bacteria and short-chain fatty acids were analysed from 67 PreventADALL study participants
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To be remembered: B cell memory response against SARS-CoV-2 and its variants in vaccinated and unvaccinated individuals Scand. J. Immunol. (IF 3.7) Pub Date : 2023-12-06 Nafees Ahmed, Atharv Athavale, Ankita H. Tripathi, Adarsh Subramaniam, Santosh K. Upadhyay, Anil Kumar Pandey, Ramesh Chandra Rai, Amit Awasthi
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The prize of prizes: mRNA research paving the way for COVID-19 vaccine success wins the Nobel Prize in Physiology or Medicine 2023. Scand. J. Immunol. (IF 3.7) Pub Date : 2023-12-01 Marcus Buggert,Petter Höglund
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Phosphorylated p38 MAP kinase expression by leucocytes is increased in allergic humans and associated with IgE responses Scand. J. Immunol. (IF 3.7) Pub Date : 2023-11-30 Jonathan I. Silverberg, Tamar A. Smith-Norowitz, Stephan Kohlhoff, Rauno Joks
Mitogen-activated protein kinases (MAPK) activate cascades that regulate cell proliferation, differentiation and death. Phosphorylated (phos-)p38 MAPK is a cell-signalling pathway associated with Th2 cytokine responses, which is required for immunoglobulin (Ig)E production. It is unknown whether MAPK are associated with IgE production. We examine the evidence linking p38 MAPK to inflammatory responses
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Identifying a core protein signature of small extracellular vesicles derived from B-cell precursor acute lymphoblastic leukaemia Scand. J. Immunol. (IF 3.7) Pub Date : 2023-11-27 Nathaniel Edward Bennett Saidu, Miriam Aarsund, Eva Sørensen, Maria Stensland, Tuula Anneli Nyman, Aina Ulvmoen, Yunjie Wu, Marit Inngjerdingen
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BCG infection dose guides dendritic cell migration and T cell priming in the draining lymph node Scand. J. Immunol. (IF 3.7) Pub Date : 2023-11-21 Veronika Krmeská, Lei Shen, Susanne Nylén, Pryscilla Fanini Wowk, Antonio Gigliotti Rothfuchs
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Differences in toll-like receptor ligand-induced cytokine concentrations before and after solid organ transplantation: A prospective, observational cohort study in a clinical setting Scand. J. Immunol. (IF 3.7) Pub Date : 2023-11-20 Dina Leth Møller, Søren Schwartz Sørensen, Michael Perch, Finn Gustafsson, Annemette Hald, Andreas Delhbæk Knudsen, Ranya Abdulovski, Nicoline Stender Arentoft, Jens Lundgren, Allan Rasmussen, Sisse Rye Ostrowski, Susanne Dam Nielsen
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Anti-inflammatory and antioxidative actions of tacrolimus (FK506) on human microglial HMC3 cell line Scand. J. Immunol. (IF 3.7) Pub Date : 2023-11-13 Fatma Gonca Kocanci, Azize Yasemin Goksu
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Transient hypogammaglobulinemia of infancy and unclassified syndromic immunodeficiencies are highly common in oesophageal atresia patients Scand. J. Immunol. (IF 3.7) Pub Date : 2023-11-12 Hilmican Ulman, Ayşe Aygün, Deniz Çağlar, Zafer Dökümcü, Ezgi Topyıldız, Ata Erdener, Güzide Aksu, Neslihan Edeer Karaca, Coşkun Özcan, Necil Kütükçüler
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Role of bacteria and microbial metabolites in immune modulation during early life Scand. J. Immunol. (IF 3.7) Pub Date : 2023-10-17 Tine Simensen Oldereid, Xiaojun Jiang, Kathrine Sivertsen Nordhus, Andrea Ponzetta, Jørgen Vildershøj Bjørnholt, Niklas K. Björkström, Espen Melum, Henrik Rasmussen
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Research progress on intestinal tissue-resident memory T cells in inflammatory bowel disease Scand. J. Immunol. (IF 3.7) Pub Date : 2023-10-17 Ke Chen, Xin Gu, Shufan Yang, Rui Tao, Menglei Fan, Wenyang Bao, Xiaoyun Wang
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A large single-center cohort of bare lymphocyte syndrome: Immunological and genetic features in Turkey Scand. J. Immunol. (IF 3.7) Pub Date : 2023-10-15 Hilal Ünsal, Canan Caka, Hacer Neslihan Bildik, Saliha Esenboğa, Alphan Kupesiz, Barış Kuşkonmaz, Duygu Uçkan Cetinkaya, Mirjam van der Burg, İlhan Tezcan, Deniz Çağdaş
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IgG exacerbates genital chlamydial pathology in females by enhancing pathogenic CD8+ T cell responses Scand. J. Immunol. (IF 3.7) Pub Date : 2023-10-13 Charles W. Armitage, Connor P. O'Meara, Emily R. Bryan, Avinash Kollipara, Logan K. Trim, Danica Hickey, Alison J. Carey, Wilhelmina M. Huston, Gavin Donnelly, Anusch Yazdani, Richard S. Blumberg, Kenneth W. Beagley
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No indication of aberrant neutrophil extracellular trap release in indolent or advanced systemic mastocytosis Scand. J. Immunol. (IF 3.7) Pub Date : 2023-10-08 Axel Rosell, Cecilia Karlström, Joakim S. Dahlin, Daryl Boey, Monika Klimkowska, Kajsa Ax, Charlotte Thålin, Johanna Ungerstedt
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Slit2 suppresses endotoxin-induced uveitis by inhibiting the PI3K/Akt/IKK/NF-κB pathway Scand. J. Immunol. (IF 3.7) Pub Date : 2023-09-28 Yong Du, Linbin Zhou, Zijun Wen, Lujia Feng, Shaochong Zhang, Ting Zhang
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Method for high-plex analysis of immune cells in human skin using the GeoMx system Scand. J. Immunol. (IF 3.7) Pub Date : 2023-09-19 Borislav Ignatov, Daniel Sortebech, Thomas Emmanuel, Ekaterina Zhuravleva, Liv Eidsmo
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Deciphering the tumour immune microenvironment of hepatocellular carcinoma Scand. J. Immunol. (IF 3.7) Pub Date : 2023-09-12 Sha Liu, Man Jia, Rongyang Dai
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Pimecrolimus protects neuron-like SH-SY5Y cells against anti-inflammatory and anti-oxidant effects of both microglial secretome and hydrogen peroxide Scand. J. Immunol. (IF 3.7) Pub Date : 2023-09-11 Fatma Gonca Kocanci, Azize Yasemin Goksu Erol, Fatma Yildiz, Hamiyet Eciroglu
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Revisiting the relationship between complement and ulcerative colitis Scand. J. Immunol. (IF 3.7) Pub Date : 2023-09-11 Yujie Ma, Kaicheng Zhang, Yuanyuan Wu, Xiaoyan Fu, Shujuan Liang, Meiyu Peng, Juntang Guo, Meifang Liu
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Sphingosine 1-phosphate combining with S1PR4 promotes regulatory T cell differentiation related to FAO through Nrf2/PPARα Scand. J. Immunol. (IF 3.7) Pub Date : 2023-08-29 Rui Feng, Chuang Liu, Zilin Cui, Zirong Liu, Yamin Zhang
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The inverse association between the apolipoprotein E ε4 allele and C-reactive protein levels is stronger in persons with obesity and diabetes Scand. J. Immunol. (IF 3.7) Pub Date : 2023-08-23 Lasse Melvaer Giil, Silja Hanseth, Ognjen Bojovic, Jan Erik Nordrehaug, Per Magne Ueland, Klaus Meyer, Grethe S. Tell
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Relapsing/remitting multiple sclerosis: A speculative model and its implications for a novel treatment Scand. J. Immunol. (IF 3.7) Pub Date : 2023-08-21 Peter Bretscher
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Synovial inducible costimulator is correlated with severity in knee osteoarthritis Scand. J. Immunol. (IF 3.7) Pub Date : 2023-08-13 Lvlin Yang, Jun Ma, Pengying Niu, Bowen Zhang, Zhiyan Wang
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Biological treatment in severe psoriasis: Influence on peripheral blood dendritic cells Scand. J. Immunol. (IF 3.7) Pub Date : 2023-08-13 Aleksandra Petrovic, Lisa Lynn Ten Bergen, Silje Michelsen Solberg, Irene Sarkar, Brith Bergum, Richard Davies, Roland Jonsson, Silke Appel
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Nocardia rubra cell wall skeleton regulates tumour-associated macrophage polarization by reprogramming M2 macrophages into M1 macrophages via STAT1/STAT6 pathways Scand. J. Immunol. (IF 3.7) Pub Date : 2023-08-11 Wei Chen, Qianyu Guo, Yi Zhang, Qianwen Liu, Yanan Zhang, Chunfang Zhao, Xuehui Li, Xue Bai, Lei Zhang, Suxia Shao
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Progress in research on the role played by myeloid-derived suppressor cells in liver diseases Scand. J. Immunol. (IF 3.7) Pub Date : 2023-08-08 Qianqian Sun, Heng Dai, Siliang Wang, Yuanyuan Chen, Huilian Shi
Myeloid-derived suppressor cells (MDSCs) refer to a group of immature myeloid cells with potent immunosuppressive capacity upon activation by pathological conditions. Because of their potent immunosuppressive ability, MDSCs have garnered extensive attention in the past few years in the fields of oncology, infection, chronic inflammation and autoimmune diseases. Research on MDSCs in liver diseases has
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Human leptospirosis: In search for a better vaccine Scand. J. Immunol. (IF 3.7) Pub Date : 2023-08-07 Isabela Resende Azevedo, Thais Akemi Amamura, Lourdes Isaac
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Implications of CD45RA and CD45RO T cell subsets in patients of chronic rhinosinusitis with nasal polyposis infected with Aspergillus flavus Scand. J. Immunol. (IF 3.7) Pub Date : 2023-08-07 Gargi Rai, Shukla Das, Mohammad Ahmad Ansari, Praveen Kumar Singh, Sajad Ahmad Dar, Neelima Gupta, Sonal Sharma, Vishnampettai Ganapathysubramanian Ramachandran, Charu Jain
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Sirtuin 2 up-regulation suppresses the anti-tumour activity of exhausted natural killer cells in mesenteric lymph nodes in murine colorectal carcinoma Scand. J. Immunol. (IF 3.7) Pub Date : 2023-08-07 Bin Jiang, Chao Ke, Hongjian Zhou, Tian Xia, Xingwang Xie, Hanbin Xu
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Aicardi–Goutières syndrome: A monogenic type I interferonopathy Scand. J. Immunol. (IF 3.7) Pub Date : 2023-07-29 Anran Liu, Songcheng Ying
Aicardi–Goutières syndrome (AGS) is a rare monogenic autoimmune disease that primarily affects the brains of children patients. Its main clinical features include encephalatrophy, basal ganglia calcification, leukoencephalopathy, lymphocytosis and increased interferon-α (IFN-α) levels in the patient's cerebrospinal fluid (CSF) and serum. AGS may be caused by mutations in any one of nine genes (TREX1
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Mild-to-moderate COVID-19 does not predispose to the development of autoimmune rheumatic diseases or autoimmune-based thrombosis Scand. J. Immunol. (IF 3.7) Pub Date : 2023-07-26 Paweł Kozłowski, Michalina Lulek, Agata Skwarek, Marcin Śmiarowski, Milena Małecka-Giełdowska, Olga Ciepiela
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On antigen-specific signals, immune class regulation and energetics: Report III from the workshops on foundational concepts of immune regulation Scand. J. Immunol. (IF 3.7) Pub Date : 2023-07-11 Colin C. Anderson, Elizabeth A. Bonney, Thomas F. Mueller, Alexandre Corthay, Calliopi Havele, Nevil J. Singh, Inger Øynebråten, Peter A. Bretscher
This is a report from a one-week workshop held in Athens, Greece in July of 2022. The workshop aimed to identify emerging concepts relevant to the fundamentals of immune regulation and areas for future research. Theories of immune regulation emphasize the role of T cell help or co-stimulation (signal 2). The workshop participants considered how new data on the characteristics of agonist antigens, the
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Regulation of B-1 cell numbers and B cell-mediated antibody production by Inpp4b Scand. J. Immunol. (IF 3.7) Pub Date : 2023-06-30 Meizhen Xu, Jinfeng Ren, Wenyu Jia, Siyu Wang, Yuting Liu, Xinzhu Chen, Jianhong Shi, Hui Wang
T and B lymphocytes are crucial players in cellular and humoral immune responses. The development, activation and differentiation of T and B lymphocytes are regulated by the best characterized PI3K-PI (3,4,5) P3-AKT phosphoinositide signalling pathway. As a branch of the phosphoinositide signalling pathway, the lipid phosphatase INPP4B inhibits AKT activation through degrading the phosphoinositide
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Comparison of BNT162b2 and mRNA1273 vaccines in solid organ transplant recipients: Post-Hoc analysis of a Japanese national prospective study Scand. J. Immunol. (IF 3.7) Pub Date : 2023-06-28 Mikiko Yoshikawa, Yoichiro Natori, Rikako Oki, Kohei Unagami, Satoko Ohfuji, Ryoichi Imamura, Hideki Ishida, Shiro Takahara, Yoshio Hirota, Hiroto Egawa
The coronavirus disease-19 (COVID-19) vaccine efficacy and immunogenicity in the immunocompetent population are well established. However, in solid organ transplant (SOT) recipients, because of their use of immunosuppressive medication, the immunogenicity of these severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines remains suboptimal. Both BNT162b2 and mRNA1273 have been used for
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Endoplasmic reticulum stress in T cell-mediated diseases Scand. J. Immunol. (IF 3.7) Pub Date : 2023-06-27 Shaodan Chen, Qiulei Wang, Hui Wang, Sheng Xia
T cells synthesize a large number of proteins during their development, activation, and differentiation. The build-up of misfolded and unfolded proteins in the endoplasmic reticulum, however, causes endoplasmic reticulum (ER) stress. Thus, T cells can maintain ER homeostasis via endoplasmic reticulum-associated degradation, unfolded protein response, and autophagy. In T cell-mediated diseases, such
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Aggregation-prone peptides from within a non-self-protein homoaggregate are preferred for MHC association: Historical overview Scand. J. Immunol. (IF 3.7) Pub Date : 2023-06-14 Donald R. Forsdyke
New technologies assist re-evaluation of hypotheses on generation of immune cell repertoires and distinctions of self from non-self. Findings include positive correlations between peptide propensities to aggregate and their binding to major histocompatibility complex (MHC) proteins. This recalls the hypothesis that foreign proteins may homoaggregate in host cytosols prior to releasing their peptides
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MCP-1/CCR2 axis is involved in the regulation of γδT cells in lupus nephritis Scand. J. Immunol. (IF 3.7) Pub Date : 2023-06-09 Ting Deng, Feifei Lei, Zhongyu Wang, Yangbin Wang, Gang Li, Yunhe Zhu, Boyu Du, Xueyan Xi
γδT cells are important innate immune cells that are involved in the occurrence and development of autoimmune diseases such as systemic lupus erythematosus (SLE). Lupus nephritis (LN) is a serious complication of SLE, characterized by the accumulation of immune cells (including γδT cells) in the target organs to participate in the disease process. Therefore, clarifying how γδT cells chemotactically
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The prognostic significance of CDK6 expression in renal cell carcinoma treated by immune checkpoint plus tyrosine kinase inhibition Scand. J. Immunol. (IF 3.7) Pub Date : 2023-06-09 Jiajun Wang, Sihong Zhang, Ying Wang, Yanjun Zhu, Xianglai Xu, Jianming Guo
Checkpoint inhibitor immunotherapy plus tyrosine kinase inhibitor (IO/TKI) has become the first-line treatment for metastatic renal cell carcinoma (RCC), despite the lack of biomarkers. Cyclin-dependent kinase 6 (CDK6) has shown a regulatory role in antitumour response. The study enrolled two cohorts of metastatic RCC treated by IO/TKI (Zhongshan Hospital [ZS]-MRCC, n = 45; JAVELIN-101, n = 726) and
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Incidence and predictors of infections in patients with advanced non-small cell lung cancer treated with checkpoint inhibitor immunotherapies: A monocentric retrospective cohort study Scand. J. Immunol. (IF 3.7) Pub Date : 2023-06-08 Davide Fiore Bavaro, Lucia Diella, Pamela Pizzutilo, Annamaria Catino, Fabio Signorile, Francesco Pesola, Alessandra Belati, Ilaria Marech, Vito Garrisi, Nino Lamorgese, Francesco Di Gennaro, Annalisa Saracino, Domenico Galetta
Immune checkpoint inhibitors (ICIs) represent the cornerstone of the current treatment of non-small cell lung cancer (NSCLC). However, the occurrence of concomitant infections might hamper success. All consecutive patients with advanced NSCLC who started ICIs as a first- or second-line therapy from January 1, 2017 to June 30, 2020 were retrospectively evaluated. The occurrence of infectious events