当前期刊: Human Immunology Go to current issue    加入关注   
显示样式:        排序: IF: - GO 导出
我的关注
我的收藏
您暂时未登录!
登录
  • Non-donor specific anti-human leukocyte antigen (HLA) antibodies are not associated with poor outcome in hematopoietic stem cell transplant recipients
    Hum. Immunol. (IF 2.202) Pub Date : 2020-05-26
    J.R. Andolina; R. Walia; J. Oliva; A. Baran; J. Liesveld; M.W. Becker; A. Busacco; M. Coppage

    Testing for anti-human leukocyte antigen (HLA) antibodies has now become standard practice in allogeneic hematopoietic stem cell transplantation (HSCT), and anti-HLA antibodies (both donor specific and non-donor specific) are being identified and have many potential consequences. Most studies suggest that donor-specific HLA antibodies lead to adverse outcomes, though little is reported on non-donor

    更新日期:2020-05-26
  • CD1 gene polymorphism and susceptibility to celiac disease: Association of CD1E*02/02 in Moroccans
    Hum. Immunol. (IF 2.202) Pub Date : 2020-05-25
    Anna Aureli; Sara Aboulaghras; Khadija Oumhani; Tiziana Del Beato; Pierluigi Sebastiani; Alessia Colanardi; Rajae El Aouad; Imane Ben El Barhdadi; Daniela Piancatelli

    CD1 glycoproteins are a class of antigen presenting molecules that bind and present non-peptidic antigens (lipids and glycolipids) for immune recognition. CD1 polymorphisms, although limited, could have a critical role in antimicrobial, anticancer, and autoimmune responses and disease susceptibility. Ethnic differences and interactions between genetic and environmental factors make it attractive the

    更新日期:2020-05-25
  • HLA study in Bolivian Quechua Amerindians from Titikaka Lake Area.
    Hum. Immunol. (IF 2.202) Pub Date : 2020-05-14
    Antonio Arnaiz-Villena,Ignacio Juarez,Adrian Lopez-Nares,Estefania Crespo-Yuste,Alvaro Callado,Fabio Suarez-Trujillo

    Quechua Amerindians established Inca Empire and chose Cuzco as their capital. Their language is closely related to that of Aymara ethnic group and both of them were originated from Titikaka Lake Altiplano area. In the present study we have analyzed Bolivian Quechua HLA profile and found that it has common characters with other Andean and Pacific Amerindians (Uros, Aymaras, Lamas, Mapuches, Athabascan)

    更新日期:2020-05-14
  • Naming HLA diversity: A review of HLA nomenclature.
    Hum. Immunol. (IF 2.202) Pub Date : 2020-05-08
    Carolyn Katovich Hurley

    The development of a standardized HLA nomenclature has been critical in our understanding of the HLA system and in facilitating the clinical applications of HLA. The Nomenclature Committee for Factors of the HLA System, established in 1968, has overseen the development and usage of nomenclature based on serologic specificities, cellular responses, and DNA sequences. Their decisions have been guided

    更新日期:2020-05-08
  • A long road/read to rapid high-resolution HLA typing: The nanopore perspective.
    Hum. Immunol. (IF 2.202) Pub Date : 2020-05-01
    Chang Liu

    Next-generation sequencing (NGS) has been widely adopted for clinical HLA typing and advanced immunogenetics researches. Current methodologies still face challenges in resolving cis-trans ambiguity involving distant variant positions, and the turnaround time is affected by testing volume and batching. Nanopore sequencing may become a promising addition to the existing options for HLA typing. The technology

    更新日期:2020-05-01
  • Distribution of HLA-A, HLA-B, HLA-C, and HLA-DRB1 alleles and haplotypes in Jingpo minority in Yunnan province of China.
    Hum. Immunol. (IF 2.202) Pub Date : 2020-04-29
    Yufen Tao,Lei Shi,Shuyuan Liu,Yufeng Yao,Li Shi

    HLA-A, HLA-B, HLA-C, and HLA-DRB1 allele frequencies and estimated haplotype frequencies from 105 unrelated healthy Jingpo ethnic subjects who living in Dehong Dai-Jingpo Autonomous Prefectures, Yunnan Province, southwest China has been reported. HLA genes were genotyped by SSOP typing method using Luminex Multi-Analyte Profiling system. Jingpo ethnic nationality belongs to southern group of East Asians

    更新日期:2020-04-29
  • Detecting mismatched donor HLA types from allograft biopsies - An easily applicable tool for improved individualized risk assessment.
    Hum. Immunol. (IF 2.202) Pub Date : 2020-04-28
    Randi Berg,Maja Nørgaard,Mie Topholm Bruun,Mette Christiansen,Pernille Koefoed-Nielsen

    Short-term allograft survival has improved among solid organ transplant (SOT) patients. An increasing number of SOT patients are prepared for re-transplantation because of chronic allograft failure. Lack of HLA typing or incomplete HLA typing of previous donors complicates pretransplant risk assessment, as repeated HLA mismatches may be missed. In addition, a complete HLA type of the donor is essential

    更新日期:2020-04-29
  • Novel immunological approach to asses donor reactivity of transplant recipients using a humanized mouse model.
    Hum. Immunol. (IF 2.202) Pub Date : 2020-04-25
    Yasutomo Fukasaku,Ryoichi Goto,Yoshikazu Ganchiku,Shin Emoto,Masaaki Zaitsu,Masaaki Watanabe,Norio Kawamura,Moto Fukai,Tsuyoshi Shimamura,Akinobu Taketomi

    In organ transplantation, a reproducible and robust immune-monitoring assay has not been established to determine individually tailored immunosuppressants (IS). We applied humanized mice reconstituted with human (hu-) peripheral blood mononuclear cells (PBMCs) obtained from living donor liver transplant recipients to evaluate their immune status. Engraftment of 2.5 × 106 hu-PBMCs from healthy volunteers

    更新日期:2020-04-25
  • Development of de novo HLA donor specific antibodies (HLA-DSA), HLA antibodies (HLA-Ab) and allograft rejection post blood transfusion in kidney transplant recipients.
    Hum. Immunol. (IF 2.202) Pub Date : 2020-04-20
    M Jalalonmuhali,R P Carroll,E Tsiopelas,P Clayton,P T Coates

    BACKGROUND Blood transfusion during the post-operative period of kidney transplantation is common as part of a life-saving procedure, especially in the event of acute blood loss. However, there have been conflicting opinions since the pre-cyclosporine era. The risk of sensitization post-transfusion remains the main limiting factor following transfusion in kidney transplant recipients. Thus, the objective

    更新日期:2020-04-21
  • A role for both HLA-F and HLA-G in reproduction and during pregnancy?
    Hum. Immunol. (IF 2.202) Pub Date : 2019-09-24
    Gry Persson,Nanna Jørgensen,Line Lynge Nilsson,Lærke Heidam J Andersen,Thomas Vauvert F Hviid

    The human major histocompatibility complex includes a group of non-classical HLA class I genes, HLA-E, -F and -G. While nearly all focus since the discovery of these class Ib molecules have been on basic biochemistry and molecular biology of HLA-G and HLA-E, as well as their expression patterns, functions in immune modulation and during pregnancy, and also possible implications in a range of diseases

    更新日期:2020-04-21
  • HLA-G +3196 polymorphism as a risk factor for cell mediated rejection following heart transplant.
    Hum. Immunol. (IF 2.202) Pub Date : 2020-01-09
    Mitchell B Adamson,Bennett Di Giovanni,Roberto V P Ribeiro,Frank Yu,Julieta Lazarte,Vivek Rao,Diego H Delgado

    BACKGROUND Rejection is a leading cause of mortality following heart transplantation. Human leukocyte antigen-G (HLA-G) is an immune checkpoint which dampens the immune response. Reports suggest elevated HLA-G expression is associated with reduced allograft rejection. Our objective was to evaluate HLA-G polymorphisms and cell mediated rejection (CMR) development. METHODS Recipients (n = 123) were genotyped

    更新日期:2020-04-21
  • HLA-G 3' untranslated region gene variants are promising prognostic factors for BK polyomavirus replication and acute rejection after living-donor kidney transplant.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-10-31
    Hana Rohn,Esther Schwich,Rafael Tomoya Michita,Sabine Schramm,Sebastian Dolff,Anja Gäckler,Johannes Korth,Falko M Heinemann,Benjamin Wilde,Mirko Trilling,Peter A Horn,Andreas Kribben,Oliver Witzke,Vera Rebmann

    The immunosuppressive non-classical human leukocyte antigen-G (HLA-G) promotes transplant tolerance as well as viral immune escape. HLA-G expression is associated with regulatory elements targeting certain single nucleotide polymorphisms (SNPs) in the HLA-G 3' untranslated region (UTR). Thus, we evaluated the impact of HLA-G 3'UTR polymorphisms as surrogate markers for BK polyomavirus (BKPyV) replication

    更新日期:2020-04-21
  • Soluble HLA-G pre-transplant levels to identify the risk for development of infection in heart transplant recipients.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-10-31
    Daria Bortolotti,Valentina Gentili,Antonella Rotola,Luciano Potena,Roberta Rizzo

    Infection is still a leading cause of death during the first year after heart transplantation. We evaluated the pre-transplant levels of HLA (Human Leukocyte antigen) - G molecules as a means of identifying heart recipients at risk of serious infections. We prospectively analyzed 122 adult heart transplant (HT) recipients. Serum samples were collected beforetransplantation and analyzed for sHLA-G levels

    更新日期:2020-04-21
  • Plasma soluble HLA-G levels in a cohort of heart failure patients exposed to chemicals
    Hum. Immunol. (IF 2.202) Pub Date : 2019-12-02
    Daria Bortolotti; Emanuela Vitali; Mariarita Stendardo; Alessandro Fucili; Roberta Rizzo; Piera Boschetto

    Heart failure (HF) is a syndrome caused by structural and/or functional cardiac abnormalities, resulting in a reduced cardiac output and/or elevated intracardiac pressures. Several studies reported a crucial role of immune activation and inflammation in the chronic heart failure (HF) pathogenesis, suggesting that pro-inflammatory and anti-inflammatory mediators could be predictive markers of the HF

    更新日期:2020-04-21
  • Detection of serum soluble HLA-G levels in patients with acute ischemic stroke: A pilot study.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-11-15
    Enrico Fainardi,Daria Bortolotti,Massimiliano Castellazzi,Ilaria Casetta,Tiziana Bellini,Roberta Rizzo

    The aim of this study was to investigate the potential role of soluble Human Leukocyte Antigen-G (sHLA-G) molecules as biomarkers predicting outcome in acute ischemic stroke (AIS). Serum levels of total sHLA-G (sHLA-G1/HLA-G5) and its soluble isoforms sHLA-G1 and HLA-G5/G6 were measured by enzyme-linked immunosorbent assay (ELISA) in 92 AIS patients and healthy donors (HD). Incidence of hemorrhagic

    更新日期:2020-04-21
  • Expression of membrane-bound human leucocyte antigen-G in systemic sclerosis and systemic lupus erythematosus
    Hum. Immunol. (IF 2.202) Pub Date : 2019-12-14
    Simone Negrini; Paola Contini; Francesca Pupo; Monica Greco; Giuseppe Murdaca; Francesco Puppo

    Human leucocyte antigen-G (HLA-G) is a nonclassical class I major histocompatibility complex (MHC) molecule characterized by complex immunoregulatory and tolerogenic functions. Membrane-bound HLA-G is expressed on the surface of different cell populations in both physiological and pathological conditions. Systemic sclerosis (SSc) is a multisystem autoimmune disease characterized by widespread tissue

    更新日期:2020-04-21
  • Cytometry-based analysis of HLA-G functions according to ILT2 expression.
    Hum. Immunol. (IF 2.202) Pub Date : 2020-02-18
    A Jacquier,C Dumont,E D Carosella,N Rouas-Freiss,J LeMaoult

    HLA-G was described as a molecule inhibiting NK and T cells functions through its receptor, ILT2. However, most functional studies of HLA-G were so far performed on heterogeneous immune populations and regardless of ILT2 expression. This may lead to an underestimation of the effect of HLA-G. Thus, considering the immune subpopulations sensitive to HLA-G remained an important issue in the field. Here

    更新日期:2020-04-21
  • HLA-G and humanized mouse models as a novel therapeutic approach in transplantation
    Hum. Immunol. (IF 2.202) Pub Date : 2020-02-21
    Ashwin Ajith; Vera Portik-Dobos; Daniel D. Horuzsko; Rajan Kapoor; Laura L. Mulloy; Anatolij Horuzsko

    HLA-G is a nonclassical MHC-Class I molecule whose expression, along the feto-maternal barrier contributes towards tolerance of the semiallogeneic fetus during pregnancy. In light of its inhibitory properties, recent research has established HLA-G involvement in mechanisms responsible for directing allogeneic immune responses towards tolerance during allogeneic situations such as organ transplantation

    更新日期:2020-04-21
  • Therapeutic effects of soluble human leukocyte antigen G2 isoform in lupus-prone MRL/lpr mice.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-11-14
    Hiroshi Watanabe,Kimiko Kuroki,Chisato Yamada,Yukari Saburi,Naoyoshi Maeda,Katsumi Maenaka

    Human leukocyte antigen (HLA)-G, a non-classical HLA class I molecule, has one of the splicing isoforms, HLA-G2, which lacks one domain (α2) and forms a non-covalent homodimer. HLA-G2 is expressed on placental cells, regulatory T cells, tumor cells, and virus-infected cells, and is involved in immunosuppression. The major isoform of HLA-G, HLA-G1, binds to leukocyte immunoglobulin (Ig)-like receptor

    更新日期:2020-04-21
  • HLA-DQ mismatches stimulate de novo donor specific antibodies in heart transplant recipients.
    Hum. Immunol. (IF 2.202) Pub Date : 2020-04-16
    Xiaohai Zhang,Evan Kransdorf,Ryan Levine,Jignesh K Patel,Jon A Kobashigawa

    The development of donor specific antibody is associated with graft rejection and increased mortality in solid organ transplant recipients. The majority of de novo donor specific antibodies (dnDSA) are against HLA-DQ antigens, but it has not been investigated if this is caused by more mismatches in the HLA-DQ locus between the recipient and donor. Here we examined the impact of HLA mismatches in eight

    更新日期:2020-04-21
  • Genetic diversity of HLA system in two populations from Querétaro, Mexico: Querétaro city and rural Querétaro.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-07-25
    Julio César Martínez-Álvarez,Rodrigo Barquera,Diana Iraíz Hernández-Zaragoza,Alicia Bravo-Acevedo,Stephen Clayton,Esteban Arrieta-Bolaños,Alexander Immel,Gamaliel Benítez-Arvizu,María Araceli Arrazola-García,Vicencio Juárez-Barreto,María Del Rosario Vega-Martínez,Francisco Juárez-Nicolás,Ariadna Berenice Escutia-González,Virginia Martínez-Bezies,Raquel García-Álvarez,Norma Salgado-Galicia,Joaquín Zúñiga

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 88 Mexicans from the state of Querétaro living in the city of Querétaro (N = 45) and rural communities (N = 43), to obtain information regarding allelic and haplotypic frequencies. We find that the most frequent haplotypes in the state of Querétaro include seven Native American, two European and one

    更新日期:2020-04-21
  • Genetic diversity of HLA system in six populations from Mexico City Metropolitan Area, Mexico: Mexico City North, Mexico City South, Mexico City East, Mexico City West, Mexico City Center and rural Mexico City.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-07-25
    Rodrigo Barquera,Julio César Martínez-Álvarez,Diana Iraíz Hernández-Zaragoza,Alicia Bravo-Acevedo,Francisco Juárez-Nicolás,Agustín Jericó Arriaga-Perea,María Del Rosario Vega-Martínez,Andrea Ortega-Yáñez,Gamaliel Benítez-Arvizu,Esteban Arrieta-Bolaños,Stephen Clayton,Eva Dolores Juárez-Cortés,Concepción López-Gil,Raquel García-Álvarez,María Araceli Arrazola-García,Virginia Martínez-Bezies,Vicencio

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 1217 Mexicans from the Mexico City Metropolitan Area living in the northern (N = 751), southern (N = 52), eastern (N = 79), western (N = 33), and central (N = 152) Mexico City, and rural communities (N = 150), to obtain information regarding allelic and haplotypic frequencies. We found that the most

    更新日期:2020-04-21
  • Genetic diversity of HLA system in two populations from San Luis Potosí, Mexico: San Luis Potosí City and rural San Luis Potosí.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-07-24
    Diana Iraíz Hernández-Zaragoza,Tirzo Jesús Rodríguez-Munguía,Rodrigo Barquera,Carmen Adalid-Sáinz,Esteban Arrieta-Bolaños,Stephen Clayton,Hanna Pacheco-Ubaldo,Liliana González-Medina,Abraham Lona-Sánchez,Alicia Bravo-Acevedo,Guadalupe Aquino-Rubio,Marisela Del Rocío González-Martínez,Héctor Delgado-Aguirre,Néstor Escareño-Montiel,Yolanda Jaramillo-Rodríguez,Antonio Salgado-Adame,Federico Juárez-de

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 117 Mexicans from the state of San Luis Potosí living in the city of San Luis Potosí (N = 30) and rural communities (N = 87), to obtain information regarding allelic and haplotypic frequencies. We find that the most frequent haplotypes in the state include 13 Native American, six European, two African

    更新日期:2020-04-21
  • Genetic diversity of HLA system in two populations from Tabasco, Mexico: Villahermosa and rural Tabasco.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-07-23
    Raúl Solís-Martínez,Rodrigo Barquera,Komathi Sree Ponnandai-Shanmugavel,María Del Rosario Vega-Martínez,Tannya Verónica Vázquez-Castillo,Esteban Arrieta-Bolaños,Stephen Clayton,Diana Iraíz Hernández-Zaragoza,Alicia Bravo-Acevedo,Alexander Immel,Norma Salgado-Galicia,Joaquín Zúñiga,Edmond J Yunis,Carolina Bekker-Méndez,Julio Granados

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 224 Mexicans from the state of Tabasco living in the city of Villahermosa (N = 82) and rural communities (N = 142), to obtain information regarding allelic and haplotypic frequencies. We found that the most frequent haplotypes in Tabasco include 13 Native American and two European haplotypes. Admixture

    更新日期:2020-04-21
  • Genetic diversity of HLA system in seven populations from Veracruz, Mexico: Veracruz city, Coatzacoalcos, Córdoba, Orizaba, Poza Rica, Xalapa and rural Veracruz.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-07-23
    Rodrigo Barquera,Concepción López-Gil,Víctor Acuña-Alonzo,María Del Rosario Vega-Martínez,Tirzo Jesús Rodríguez-Munguía,Julio César Martínez-Álvarez,Esteban Arrieta-Bolaños,Stephen Clayton,Flor Del Rocío Ramos-de la Cruz,Diana Iraíz Hernández-Zaragoza,Alicia Bravo-Acevedo,Gamaliel Benítez-Arvizu,María Araceli Arrazola-García,Guadalupe Aquino-Rubio,Vicencio Juárez-Barreto,Patricia Méndez-Mani,Tannya

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 1113 Mexicans from the state of Veracruz living in the cities of Coatzacoalcos (N = 55), Orizaba (N = 60), Córdoba (N = 56), Poza Rica (N = 45), Veracruz (N = 171), Xalapa (N = 187) and rural communities (N = 539) to obtain information regarding allelic and haplotypic frequencies. We found that the

    更新日期:2020-04-21
  • Genetic diversity of HLA system in three populations from Coahuila, Mexico: Torreón, Saltillo and rural Coahuila.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-07-23
    Carmen Adalid-Sáinz,Rodrigo Barquera,Michael H Crawford,Abraham Lona-Sánchez,Stephen Clayton,Esteban Arrieta-Bolaños,Héctor Delgado-Aguirre,Liliana González-Medina,Hanna Pacheco-Ubaldo,Diana Iraíz Hernández-Zaragoza,Alicia Bravo-Acevedo,Néstor Escareño-Montiel,Javier Morán-Martínez,Marisela Del Rocío González-Martínez,Yolanda Jaramillo-Rodríguez,Antonio Salgado-Adame,Federico Juárez-de la Cruz,Joaquín

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 684 Mexicans from the state of Coahuila living in Saltillo (N = 72), Torreón (N = 396) and rural communities (N = 216), to obtain information regarding allelic and haplotypic frequencies. We find that the ten most frequent haplotypes found in the state of Coahuila include eight Native American and two

    更新日期:2020-04-21
  • Genetic diversity of HLA system in two populations from Puebla, Mexico: Puebla city and rural Puebla.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-07-22
    Concepción López Gil,Rodrigo Barquera,María de Los Ángeles Pavón-Vargas,Flor Del Rocío Ramos-de la Cruz,Patricia Méndez-Mani,Esteban Arrieta-Bolaños,Stephen Clayton,Diana Iraíz Hernández-Zaragoza,Alicia Bravo-Acevedo,Joaquín Zúñiga,Edmond J Yunis,Carolina Bekker-Méndez,Julio Granados

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 2827 Mexicans from the state of Puebla living in the city of Puebla (N = 1994) and rural communities (N = 833), to obtain information regarding allelic and haplotypic frequencies. We found that the 16 most frequent haplotypes in Puebla are all of them Native American. Admixture estimates revealed that

    更新日期:2020-04-21
  • Genetic diversity of HLA system in two populations from Tamaulipas, Mexico: Ciudad Victoria and rural Tamaulipas.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-07-22
    Tirzo Jesús Rodríguez-Munguía,Rodrigo Barquera,Carmen Adalid-Sáinz,Diana Iraíz Hernández-Zaragoza,Esteban Arrieta-Bolaños,Stephen Clayton,Guadalupe Aquino-Rubio,Marisela Del Rocío González-Martínez,Hanna Pacheco-Ubaldo,Liliana González-Medina,Abraham Lona-Sánchez,Alicia Bravo-Acevedo,Héctor Delgado-Aguirre,Néstor Escareño-Montiel,Yolanda Jaramillo-Rodríguez,Antonio Salgado-Adame,Federico Juárez-de

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 148 Mexicans from the state of Tamaulipas living in Ciudad Victoria (N = 23) and rural communities (N = 125), to obtain information regarding allelic and haplotypic frequencies. We found that the most frequent haplotypes in the state of Tamaulipas include ten Native American, three European and one

    更新日期:2020-04-21
  • Genetic diversity of HLA system in two populations from Quintana Roo, Mexico: Cancún and rural Quintana Roo.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-07-22
    Carolina Elizabeth Medina-Escobedo,Rodrigo Barquera,Komathi Sree Ponnandai-Shanmugavel,Julio Lara-Riegos,Alicia Bravo-Acevedo,Esteban Arrieta-Bolaños,Stephen Clayton,Diana Iraíz Hernández-Zaragoza,Joaquín Zúñiga,Edmond J Yunis,Carolina Bekker-Méndez,Julio Granados

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 98 Mexicans from the state of Quintana Roo living in the city of Cancún (N = 48) and rural communities (N = 50), to obtain information regarding allelic and haplotypic frequencies and their linkage disequilibrium. We found that the most frequent haplotypes in Quintana Roo include ten Native American

    更新日期:2020-04-21
  • Genetic diversity of HLA system in two populations from Campeche, Mexico: Campeche city and rural Campeche.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-07-22
    Rodrigo Barquera,Julio Lara-Riegos,Komathi Sree Ponnandai-Shanmugavel,Alexander Immel,Esteban Arrieta-Bolaños,Stephen Clayton,Raúl Solís-Martínez,Alicia Bravo-Acevedo,Tannya Verónica Vázquez-Castillo,Diana Iraíz Hernández-Zaragoza,María Del Rosario Vega-Martínez,Norma Salgado-Galicia,Carolina Elizabeth Medina-Escobedo,Joaquín Zúñiga,Edmond J Yunis,Carolina Bekker-Méndez,Julio Granados

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 81 Mexicans from the state of Campeche living in the city of Campeche (N = 34) and rural communities (N = 47), to obtain information regarding allelic and haplotypic frequencies. We find that the most frequent haplotypes in the state of Campeche include ten Native American, three European, one African

    更新日期:2020-04-21
  • Genetic diversity of HLA system in two populations from Chiapas, Mexico: Tuxtla Gutiérrez and rural Chiapas.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-07-22
    Rodrigo Barquera,Francisco Juárez-Nicolás,Julio César Martínez-Álvarez,Komathi Sree Ponnandai-Shanmugavel,Diana Iraíz Hernández-Zaragoza,Tannya Verónica Vázquez-Castillo,Esteban Arrieta-Bolaños,Stephen Clayton,Raúl Solís-Martínez,Andrea Ortega-Yáñez,María Araceli Arrazola-García,Alexander Immel,Alicia Bravo-Acevedo,María Del Rosario Vega-Martínez,Gamaliel Benítez-Arvizu,Raquel García-Álvarez,Virginia

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 173 Mexicans from the state of Chiapas living in the city of Tuxtla Gutiérrez (N = 52) and rural communities (N = 121), to obtain information regarding allelic and haplotypic frequencies. We found that the most frequent haplotypes in Chiapas include 12 Native American and one European haplotype. Admixture

    更新日期:2020-04-21
  • Genetic diversity of HLA system in two populations from Tlaxcala, Mexico: Tlaxcala city and rural Tlaxcala.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-07-22
    María de Los Ángeles Pavón-Vargas,Michael H Crawford,Rodrigo Barquera,Concepción López-Gil,Esteban Arrieta-Bolaños,Stephen Clayton,Diana Iraíz Hernández-Zaragoza,Alicia Bravo-Acevedo,Flor Del Rocío Ramos-de la Cruz,Patricia Méndez-Mani,Joaquín Zúñiga,Edmond J Yunis,Carolina Bekker-Méndez,Julio Granados

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 1011 Mexicans from the state of Tlaxcala residing in the city of Tlaxcala (N = 181) and rural communities (N = 830), to obtain information regarding allelic and haplotypic frequencies. We find that the ten most frequent haplotypes in Tlaxcala are all of Native American origin. Admixture estimates revealed

    更新日期:2020-04-21
  • Genetic diversity of HLA system in two populations from Yucatán, Mexico: Mérida and rural Yucatán.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-07-22
    Julio Lara-Riegos,Rodrigo Barquera,Oana Del Castillo-Chávez,Carolina Elizabeth Medina-Escobedo,Diana Iraíz Hernández-Zaragoza,Esteban Arrieta-Bolaños,Stephen Clayton,Komathi Sree Ponnandai-Shanmugavel,Alicia Bravo-Acevedo,Joaquín Zúñiga,Edmond J Yunis,Carolina Bekker-Méndez,Julio Granados

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 324 Mexicans from the state of Yucatán living in the city of Mérida (N = 192) and rural communities (N = 132), to obtain information regarding allelic and haplotypic frequencies. We found that the most frequent haplotypes in the state of Yucatán include 16 Native American and one European haplotype

    更新日期:2020-04-21
  • Genetic diversity of HLA system in two populations from Hidalgo, Mexico: Pachuca and rural Hidalgo.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-07-22
    Rodrigo Barquera,Julio César Martínez-Álvarez,Alondra Victoria Trejo-Ordoz,María de Los Ángeles Pavón-Vargas,María Del Rosario Vega-Martínez,Esteban Arrieta-Bolaños,Stephen Clayton,Andrea Ortega-Yáñez,Eva Dolores Juárez-Cortés,Francisco Juárez-Nicolás,Concepción López-Gil,Alexander Immel,María Araceli Arrazola-García,Vicencio Juárez-Barreto,Gamaliel Benítez-Arvizu,Agustín Jericó Arriaga-Perea,Virginia

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 122 Mexicans from the state of Hidalgo living in the city of Pachuca (N = 41) and rural communities (N = 81), to obtain information regarding allelic and haplotypic frequencies. We find that the most frequent haplotypes in Hidalgo include eight Native American and one European haplotypes. Admixture

    更新日期:2020-04-21
  • Genetic diversity of HLA system in two populations from Morelos, Mexico: Cuernavaca and rural Morelos.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-07-22
    Andrea Ortega-Yáñez,Rodrigo Barquera,Laura Curiel-Giles,Julio César Martínez-Álvarez,Rosa María Macías-Medrano,Esteban Arrieta-Bolaños,Stephen Clayton,Alicia Bravo-Acevedo,Diana Iraíz Hernández-Zaragoza,Alexander Immel,María Del Rosario Vega-Martínez,Gamaliel Benítez-Arvizu,María Araceli Arrazola-García,Agustín Jericó Arriaga-Perea,Eva Dolores Juárez-Cortés,Vicencio Juárez-Barreto,Norma Salgado-Galicia

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 112 Mexicans from the state of Morelos living in the city of Cuernavaca (N = 82) and rural communities (N = 30), to obtain information regarding allelic and haplotypic frequencies. The most frequent haplotypes in Morelos include seven Native American, one European, one African and one Asian haplotype

    更新日期:2020-04-21
  • Genetic diversity of HLA system in two populations from Oaxaca, Mexico: Oaxaca city and rural Oaxaca.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-07-22
    Ofelia Hernández-Hernández,Diana Iraíz Hernández-Zaragoza,Rodrigo Barquera,Christina Warinner,Concepción López-Gil,Esteban Arrieta-Bolaños,Stephen Clayton,Alicia Bravo-Acevedo,Flor Del Rocío Ramos-de la Cruz,Patricia Méndez-Mani,María de Los Ángeles Pavón-Vargas,Joaquín Zúñiga,Edmond J Yunis,Carolina Bekker-Méndez,Julio Granados

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 636 Mexicans from the state of Oaxaca living in the city of Oaxaca (N = 151) and rural communities (N = 485), to obtain information regarding allelic and haplotypic frequencies. We found that the 13 most frequent haplotypes in Oaxaca are all of putative Native American origin. Admixture estimates revealed

    更新日期:2020-04-21
  • Genetic diversity of HLA system in three populations from Guanajuato, Mexico: Guanajuato City, León and rural Guanajuato.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-06-14
    Jorge Arturo Pantoja-Torres,Rodrigo Barquera,Mónica Ballesteros-Romero,Alicia Bravo-Acevedo,Esteban Arrieta-Bolaños,Gustavo Daniel Montiel-Hernández,Stephen Clayton,Lidia Iris Rodríguez-Rodríguez,Diana Iraíz Hernández-Zaragoza,Isis Goné-Vázquez,Araceli Escobedo-Ruíz,Víctor Eduardo García-Arias,Francia Paulina Arellano-Prado,Marla Estefanía Rodríguez-López,María Guadalupe de Jesús Sánchez-Fernández

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 262 Mexicans from the state of Guanajuato living in the cities of Guanajuato (N = 78), León (N = 22) and rural communities (N = 162), to obtain information regarding allelic and haplotypic frequencies. We find that the most frequent haplotypes found in the state of Guanajuato include 12 Native American

    更新日期:2020-04-21
  • Genetic diversity of HLA system in two populations from Colima, Mexico: Colima city and rural Colima.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-06-14
    Rodrigo Barquera,Diana Iraíz Hernández-Zaragoza,Francia Paulina Arellano-Prado,Isis Goné-Vázquez,Stephen Clayton,Esteban Arrieta-Bolaños,Araceli Escobedo-Ruíz,Víctor Eduardo García-Arias,Alicia Bravo-Acevedo,Marla Estefanía Rodríguez-López,María Guadalupe de Jesús Sánchez-Fernández,Mario J Sandoval-Sandoval,Benjamín Gómez-Navarro,Joaquín Zúñiga,Edmond J Yunis,Carolina Bekker-Méndez,Julio Granados

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 104 Mexicans from the state of Colima living in the city of Colima (N = 61) and rural communities (N = 43), to obtain information regarding allelic and haplotypic frequencies. We find that the most frequent haplotypes in the state of Colima include eight Native American, two European and one African

    更新日期:2020-04-21
  • Genetic diversity of HLA system in two populations from Durango, Mexico: Durango city and rural Durango.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-06-11
    Liliana González-Medina,Rodrigo Barquera,Héctor Delgado-Aguirre,Stephen Clayton,Carmen Adalid-Sáinz,Esteban Arrieta-Bolaños,Hanna Pacheco-Ubaldo,Diana Iraíz Hernández-Zaragoza,Néstor Escareño-Montiel,Javier Morán-Martínez,Alicia Bravo-Acevedo,Abraham Lona-Sánchez,Marisela Del Rocío González-Martínez,Yolanda Jaramillo-Rodríguez,Antonio Salgado-Adame,Federico Juárez-de la Cruz,Joaquín Zúñiga,Edmond J

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 479 Mexicans from the state of Durango living in Durango city (N = 153) and rural communities (N = 326), to obtain information regarding allelic and haplotypic frequencies. We find that the ten most frequent haplotypes found in the state of Durango include eight Native American and two European haplotypes

    更新日期:2020-04-21
  • Genetic diversity of HLA system in two populations from Nuevo León, Mexico: Monterrey and rural Nuevo León.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-06-11
    Rodrigo Barquera,Alicia Bravo-Acevedo,Stephen Clayton,Tirzo Jesús Rodríguez Munguía,Diana Iraíz Hernández-Zaragoza,Carmen Adalid-Sáinz,Esteban Arrieta-Bolaños,Guadalupe Aquino-Rubio,Marisela Del Rocío González-Martínez,Abraham Lona-Sánchez,Julio César Martínez-Álvarez,María Araceli Arrazola-García,Héctor Delgado-Aguirre,Liliana González-Medina,Hanna Pacheco-Ubaldo,Vicencio Juárez-Barreto,Gamaliel Benítez-Arvizu

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 665 Mexicans from the state of Nuevo León living in the city of Monterrey (N = 226) and rural communities (N = 439), to obtain information regarding allelic and haplotypic frequencies. We find that the most frequent haplotypes in the state of Nuevo León include 12 Native American and three European

    更新日期:2020-04-21
  • Genetic diversity of HLA system in two populations from Sinaloa, Mexico: Culiacán and rural Sinaloa.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-06-11
    Stephen Clayton,Rodrigo Barquera,María Guadalupe Uribe-Duarte,Isis Goné Vázquez,Joaquín Zúñiga,Esteban Arrieta-Bolaños,Diana Iraíz Hernández-Zaragoza,María de Jesús Ruíz-Corral,Araceli Escobedo-Ruíz,Francia Paulina Arellano-Prado,Víctor Eduardo García-Arias,Marla Estefanía Rodríguez-López,Alicia Bravo-Acevedo,María Guadalupe de Jesús Sánchez-Fernández,Jesús Abraham Aguilar-Campos,Ricardo Serrano-Osuna

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 286 Mexicans from the state of Sinaloa living in Culiacán (N = 103) and rural communities (N = 183) to obtain information regarding allelic and haplotypic frequencies. We find that the most frequent haplotypes for the state of Sinaloa include ten Native American most probable ancestry and five European

    更新日期:2020-04-21
  • Genetic diversity of HLA system in four populations from Baja California, Mexico: Mexicali, La Paz, Tijuana and rural Baja California.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-06-11
    Araceli Escobedo-Ruíz,Rodrigo Barquera,Antonio González-Martín,Juan Manuel Argüelles-San Millán,María Guadalupe Uribe-Duarte,Diana Iraíz Hernández-Zaragoza,Stephen Clayton,Esteban Arrieta-Bolaños,María de Jesús Ruíz-Corral,Isis Goné-Vázquez,Francia Paulina Arellano-Prado,Julio César Martínez-Álvarez,Víctor Eduardo García-Arias,Marla Estefanía Rodríguez-López,Alicia Bravo-Acevedo,María Guadalupe de

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 250 Mexicans from the states of Baja California Norte and Baja California Sur living in Mexicali (N = 100), La Paz (N = 75), Tijuana (N = 25) and rural communities (N = 50) to obtain information regarding allelic and haplotypic frequencies. The most frequent haplotypes for the Baja California region

    更新日期:2020-04-21
  • Genetic diversity of HLA system in two populations from Nayarit, Mexico: Tepic and rural Nayarit.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-06-11
    Isis Goné-Vázquez,Rodrigo Barquera,Francia Paulina Arellano-Prado,Diana Iraíz Hernández-Zaragoza,Araceli Escobedo-Ruíz,Stephen Clayton,Esteban Arrieta-Bolaños,Víctor Eduardo García-Arias,Marla Estefanía Rodríguez-López,Alicia Bravo-Acevedo,María Guadalupe de Jesús Sánchez-Fernández,Mario J Sandoval-Sandoval,Benjamín Gómez-Navarro,Joaquín Zúñiga,Edmond J Yunis,Carolina Bekker-Méndez,Julio Granados

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 161 Mexicans from the state of Nayarit living in Tepic (N = 97) and rural communities (N = 64), to obtain information regarding allelic and haplotypic frequencies. We find that the ten most frequent haplotypes found in the state of Nayarit include eight Native American and two European haplotypes. Admixture

    更新日期:2020-04-21
  • Genetic diversity of HLA system in a population sample from Aguascalientes, Mexico.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-06-04
    Alicia Bravo-Acevedo,Rodrigo Barquera,Esteban Arrieta-Bolaños,Diana Iraíz Hernández-Zaragoza,Stephen Clayton,Isis Goné-Vázquez,Araceli Escobedo-Ruíz,Jorge Arturo Pantoja-Torres,Carmen Adalid-Sáinz,Hanna Pacheco-Ubaldo,Julio César Martínez-Álvarez,Marisela Del Rocío González-Martínez,Abraham Lona-Sánchez,Liliana González-Medina,Néstor Escareño-Montiel,María Araceli Arrazola-García,Vicencio Juárez-Barreto

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 95 Mexicans from the state of Aguascalientes to obtain information regarding allelic and haplotypic frequencies and their linkage disequilibrium. We find that the most frequent haplotypes in the state of Aguascalientes include four Native American, three European and one Asian haplotypes. Admixture

    更新日期:2020-04-21
  • Genetic diversity of HLA system in six populations from Jalisco, Mexico: Guadalajara city, Tlajomulco, Tlaquepaque, Tonalá, Zapopan and rural Jalisco.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-06-04
    Alicia Bravo-Acevedo,Araceli Escobedo-Ruíz,Rodrigo Barquera,Stephen Clayton,Víctor Eduardo García-Arias,Esteban Arrieta-Bolaños,Isis Goné-Vázquez,Diana Iraíz Hernández-Zaragoza,Francia Paulina Arellano-Prado,Marla Estefanía Rodríguez-López,María Guadalupe de Jesús Sánchez-Fernández,Mario J Sandoval-Sandoval,Benjamín Gómez-Navarro,Joaquín Zúñiga,Edmond J Yunis,Carolina Bekker-Méndez,Julio Granados

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 2046 Mexicans from the state of Jalisco living in the city of Guadalajara (N = 1189), Tlajomulco (N = 30), Tlaquepaque (N = 39), Tonalá (N = 35), Zapopan (N = 168) and rural communities (N = 585), to obtain information regarding allelic and haplotypic frequencies. We find that the most frequent haplotypes

    更新日期:2020-04-21
  • Genetic diversity of HLA system in three populations from Sonora, Mexico: Ciudad Obregón, Hermosillo and rural Sonora.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-06-04
    María Guadalupe Uribe-Duarte,Jesús Abraham Aguilar-Campos,Rodrigo Barquera,Alicia Bravo-Acevedo,Stephen Clayton,Esteban Arrieta-Bolaños,María de Jesús Ruíz-Corral,Diana Iraíz Hernández-Zaragoza,Ricardo Serrano-Osuna,Edmond J Yunis,Joaquín Zúñiga,Carolina Bekker-Méndez,Julio Granados

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 439 Mexicans from the state of Sonora living in Ciudad Obregón (N = 143), Hermosillo (N = 99), and rural communities (N = 197) to obtain information regarding allelic and haplotypic frequencies. We find that the 13 most frequent haplotypes for the state of Sonora include nine Native American, three

    更新日期:2020-04-21
  • Genetic diversity of HLA system in a population from Guerrero, Mexico.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-06-04
    Francisco Juárez-Nicolás,Rodrigo Barquera,Julio César Martínez-Álvarez,Diana Iraíz Hernández-Zaragoza,Andrea Ortega-Yáñez,Esteban Arrieta-Bolaños,Stephen Clayton,Alicia Bravo-Acevedo,María Araceli Arrazola-García,Alexander Immel,Vicencio Juárez-Barreto,Gamaliel Benítez-Arvizu,María Del Rosario Vega-Martínez,Raquel García-Álvarez,Virginia Martínez-Bezies,Ariadna Berenice Escutia-González,Rosario Díaz-López

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 144 Mexicans from the state of Guerrero to obtain information regarding allelic and haplotypic frequencies. We find that the ten most frequent haplotypes in the state of Guerrero include eight Native American and two European haplotypes. Admixture estimates revealed that the main genetic components

    更新日期:2020-04-21
  • Genetic diversity of HLA system in three populations from Chihuahua, Mexico: Chihuahua City, Ciudad Juárez and rural Chihuahua.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-06-04
    Hanna Pacheco-Ubaldo,Carmen Adalid-Sáinz,Rodrigo Barquera,Stephen Clayton,Esteban Arrieta-Bolaños,Héctor Delgado-Aguirre,Liliana González-Medina,Diana Iraíz Hernández-Zaragoza,Néstor Escareño-Montiel,Javier Morán-Martínez,Alicia Bravo-Acevedo,Abraham Lona-Sánchez,Marisela Del Rocío González-Martínez,Yolanda Jaramillo-Rodríguez,Antonio Salgado-Adame,Federico Juárez-de la Cruz,Joaquín Zúñiga,Edmond J

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 461 Mexicans from the state of Chihuahua living in Chihuahua city (N = 119), Ciudad Juárez (N = 106) and rural communities (N = 236), to obtain information regarding allelic and haplotypic frequencies and their linkage disequilibrium. We find that the most frequent haplotypes found in the state of Chihuahua

    更新日期:2020-04-21
  • Genetic diversity of HLA system in two populations from Michoacán, Mexico: Morelia and rural Michoacán.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-06-04
    Mónica Ballesteros-Romero,Rodrigo Barquera,Marla Estefanía Rodríguez-López,Diana Iraíz Hernández-Zaragoza,Isis Goné-Vázquez,Stephen Clayton,Esteban Arrieta-Bolaños,Araceli Escobedo-Ruíz,Jorge Arturo Pantoja-Torres,Víctor Eduardo García-Arias,Francia Paulina Arellano-Prado,Alicia Bravo-Acevedo,María Guadalupe de Jesús Sánchez-Fernández,Mario J Sandoval-Sandoval,Benjamín Gómez-Navarro,Joaquín Zúñiga

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 498 Mexicans from the state of Michoacán living in the city of Morelia (N = 150) and rural communities (N = 348), to obtain information regarding allelic and haplotypic frequencies. We find that the ten most frequent haplotypes found in the state of Michoacán include 12 Native American and two European

    更新日期:2020-04-21
  • Genetic diversity of HLA system in three populations from Zacatecas, Mexico: Zacatecas city, Fresnillo and rural Zacatecas.
    Hum. Immunol. (IF 2.202) Pub Date : 2019-01-24
    Diana Iraíz Hernández-Zaragoza,Héctor Delgado-Aguirre,Rodrigo Barquera,Carmen Adalid-Sáinz,Stephen Clayton,Abraham Lona-Sánchez,Liliana González-Medina,Hanna Pacheco-Ubaldo,Alicia Bravo-Acevedo,Néstor Escareño-Montiel,Javier Morán-Martínez,Marisela Del Rocío González-Martínez,Yolanda Jaramillo-Rodríguez,Federico Juárez-de la Cruz,Joaquín Zúñiga,Edmond Yunis,Carolina Bekker-Méndez,Julio Granados

    We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 453 Mexicans from the state of Zacatecas living in Zacatecas city (N = 84), Fresnillo (N = 103) and rural communities (N = 266) to obtain information regarding allelic and haplotypic frequencies and their linkage disequilibrium. We find that the most frequent haplotypes for the state of Zacatecas include

    更新日期:2020-04-21
  • HLA study in Amerindian Bolivia La Paz Aymaras.
    Hum. Immunol. (IF 2.202) Pub Date : 2020-04-20
    Antonio Arnaiz-Villena,Ignacio Juarez,Adrian Lopez-Nares,Estefania Crespo-Yuste,Alvaro Callado,Fabio Suarez-Trujillo

    Aymara people has been a relatively homogeneous group since Spanish Conquest by 1,532 CE, even if previously represented a group of various cultural defined populations who gave rise to them. They were and are established in Andean Altiplano around Titikaka Lake (Bolivia, Peru), Argentina and Chile neighborhood, speak Aymara language and have been maintained after Europeans arrival at a lower social

    更新日期:2020-04-20
  • HLA-A, -B, -C, -DRB1 and -DQB1 alleles and haplotypes in 271 Southeast Asia Indians from Peninsular Malaysia.
    Hum. Immunol. (IF 2.202) Pub Date : 2020-04-18
    Ahmad Fauzi Nurul-Aain,Lay-Kim Tan,Hussein Heselynn,Shahril Nor-Shuhaila,Mageswaran Eashwary,Sulaiman Wahinuddin,Ing Soo Lau,Suk Chyn Gun,Mohamed-Said Mohd-Shahrir,Mohd-Mokhtar Ainon,Rosman Azmillah,Othman Muhaini,Murad Shahnaz,Chun-Lai Too

    A total of 271 Southeast Asia Indians from Peninsular Malaysia were genotyped for HLA-A, -B, -C, -DRB1, and -DQB1 loci using polymerase chain reaction sequence-specific oligonucleotide probe hybridization methods. In this report, HLA-B and HLA-DQB1 was in Hardy-Weinberg proportions (HWEP) (p > 0.05). We observed significant deviation from the HWEP for HLA-A (p < 0.05), HLA-C (p < 0.01) and HLA-DRB1

    更新日期:2020-04-18
  • Next generation sequencing of 11 HLA loci characterises a diverse UK cord blood bank.
    Hum. Immunol. (IF 2.202) Pub Date : 2020-04-16
    Sandra G Guerra,Siobhan Hamilton-Jones,Colin J Brown,Cristina V Navarrete,Winnie Chong

    The introduction of next generation sequencing (NGS) for stem cell donor registry typing has contributed to faster identification of compatible stem cell donors. However, the successful search for a matched unrelated donor for some patient groups is still affected by their ethnicity. In this study, DNA samples from 714 National Health Service (NHS) Cord Blood Bank donors were typed for HLA-A, -B, -C

    更新日期:2020-04-16
  • Overrepresentation of highly functional T regulatory cells in patients with nonfunctioning pituitary adenoma
    Hum. Immunol. (IF 2.202) Pub Date : 2020-04-09
    Song Han; Enlong Ma; Wei Jiang; Yu Lu; Xiaoyu Sun; Sizhe Feng

    Nonfunctioning pituitary adenoma is a common intracranial tumor. Though benign in the majority of cases, complications can be excruciating to the affected individual, and recurrences after tumor removal may happen with more aggressive clinical features. T regulatory (Treg) cells are generally considered a tumor-promoting immune cell type in malignant cancers with currently unclear roles in pituitary

    更新日期:2020-04-09
  • Luminex screening first vs. direct single antigen bead assays: Different strategies for HLA antibody monitoring after kidney transplantation
    Hum. Immunol. (IF 2.202) Pub Date : 2020-04-09
    Carla Burballa; María José Pérez-Saéz; Dolores Redondo-Pachón; Carme García; Marisa Mir; Carlos Arias-Cabrales; Nicole M. Valenzuela; Elaine F. Reed; Julio Pascual; Marta Crespo

    Main problem Luminex panel and single antigen beads (SAB) are used for screening and DSA specificity determination respectively. The cost of SAB may limit its general use, so some labs perform SAB tests only after positive screening. Methods We compared both strategies: 1) SAB only if positive screening with kits from manufacturer A, and 2) direct SAB from manufacturer B, and correlate their sensitivity

    更新日期:2020-04-09
  • Expression analysis of immune-regulatory molecules HLA-G, HLA-E and IDO in endometrial cancer
    Hum. Immunol. (IF 2.202) Pub Date : 2020-04-06
    Hamza Ben Yahia; Nadia Boujelbene; Wafa Babay; Inès Ben Safta; Sabrine Dhouioui; Inès Zemni; Mohamed Ali Ayadi; Lamia Charfi; Hadda Imene Ouzari; Vera Rebmann; Roberta Rizzo; Karima Mrad; Maha Driss; Inès Zidi

    HLA-G has been widely implicated in advanced cancers through different pathways of immunosuppression allowing tumor escape. Contrarily, HLA-E has a controversial role in the tumor escape from the immune system. IDO catabolic enzyme is known to be up-regulated in many tumors types allowing their immune escape. Based on these considerations, we investigated the expression of HLA-G, HLA-E and IDO molecules

    更新日期:2020-04-06
  • HLA-A, -B, -DRB1 and -DQB1 polymorphisms among Iraqi Arabs.
    Hum. Immunol. (IF 2.202) Pub Date : 2020-03-26
    Ali H Ad'hiah,Aaiad H Al-Rikabi,Zahra'a A Ahmed,Liath A Kamil

    In this report, HLA polymorphisms (A, B, DRB1 and DQB1 loci) were determined in 149 unrelated Iraqi Arab potential bone marrow and kidney donors. Molecular genotyping was carried out by polymerase chain reaction followed by specific oligonucleotide probe hybridizations. Data were analyzed by Arlequin software. HLA-A, -B and -DRB1 genotype frequencies were significantly deviated from Hardy-Weinberg

    更新日期:2020-03-26
  • HLA genes in Amerindians from Mexico San Vicente Tancuayalab Teenek/Huastecos.
    Hum. Immunol. (IF 2.202) Pub Date : 2020-03-21
    Antonio Arnaiz-Villena,Ignacio Juarez,Fabio Suarez-Trujillo,Estefania Crespo-Yuste,Adrian Lopez-Nares,Alvaro Callado,Christian Vaquero,Gilberto Vargas-Alarcon

    Huastecos or Teenek Amerindians are presently living at North East Mexico (San Luis Potosi State). They have probably one of the most ancient culture of Mexico and Central America together with Mayas and Olmec groups with which also show close relationships. Proximity to Atlantic Ocean/Mexican Gulf originated that Spaniards had very early contact with them at about 1519 CE or before. In the present

    更新日期:2020-03-21
  • Impact of donor KIRs and recipient KIR/HLA class I combinations on GVHD in patients with acute leukemia after HLA-matched sibling HSCT
    Hum. Immunol. (IF 2.202) Pub Date : 2020-03-18
    Marzieh Mansouri; Jean Villard; Mani Ramzi; Ali Alavianmehr; Shirin Farjadian

    In addition to T cells, NK cells can also participate in the outcome of hematopoietic stem cell transplantation (HSCT) mainly through the interaction between donor killer cell immunoglobulin-like receptors (KIRs) and recipient human leukocyte antigen (HLA) class I molecules. There is a risk of GVHD other than leukemia relapse after allogeneic HSCT that activation of donor NK cells in the absence of

    更新日期:2020-03-18
  • NGS and HLA: The long road ahead
    Hum. Immunol. (IF 2.202) Pub Date : 2020-03-16
    Kelly J. Ingram; Elaine F. O'Shields; David F. Kiger; Michael D. Gautreaux

    This manuscript is a continuation of this laboratory’s journey to identifying novel HLA alleles while performing routine clinical HLA laboratory testing. Since our last paper, we have identified an additional 28 novel HLA alleles that are identified and described herein. One novel allele was found in two unrelated patients that were HLA typed for different reasons at two different times, suggesting

    更新日期:2020-03-16
Contents have been reproduced by permission of the publishers.
导出
全部期刊列表>>
智控未来
聚焦商业经济政治法律
跟Nature、Science文章学绘图
控制与机器人
招募海内外科研人才,上自然官网
隐藏1h前已浏览文章
课题组网站
新版X-MOL期刊搜索和高级搜索功能介绍
ACS材料视界
x-mol收录
湖南大学化学化工学院刘松
上海有机所
廖良生
南方科技大学
西湖大学
伊利诺伊大学香槟分校
徐明华
中山大学化学工程与技术学院
试剂库存
天合科研
down
wechat
bug