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HLA class I NK-epitopes and KIR diversities in patients with multiple myeloma Immunogenetics (IF 3.2) Pub Date : 2024-03-13 Nicky A. Beelen, Stefan J. J. Molenbroeck, Lisette Groeneveld, Christien E. Voorter, Gerard M. J. Bos, Lotte Wieten
Multiple myeloma (MM) is a hematological malignancy caused by the clonal expansion of malignant plasma cells in the bone marrow. Myeloma cells are susceptible to killing by natural killer (NK) cells, but NK cells fail to control disease progression, suggesting immunosuppression. The activation threshold of NK-effector function is regulated by interaction between KIRs and self-HLA class I, during a
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Lack of Syndecan-1 promotes the pathogenesis of experimental rheumatoid arthritis Immunogenetics (IF 3.2) Pub Date : 2024-03-07 Rosalyn Jurjus, Laura Dosh, Rima Farhat, Tatiana Daccache, Jad El Masri, Maya Ghazi, Jihad Hawi, Angelo Leone, Abdo Jurjus
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Evolutionary divergence of TLR9 through ancestral sequence reconstruction Immunogenetics (IF 3.2) Pub Date : 2024-03-05 Manisha Ghosh, Surajit Basak, Shanta Dutta
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Causal effect of interleukin (IL)-6 on blood pressure and hypertension: A mendelian randomization study Immunogenetics (IF 3.2) Pub Date : 2024-03-01 Ou Wu, Ya Wu, Xingyu Zhang, Wei Liu, Hu Zhang, Saber Khederzadeh, Xi Lu, Xiao-Wei Zhu
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Resolving unknown nucleotides in the IPD-IMGT/HLA database by extended and full-length sequencing of HLA class I and II alleles Immunogenetics (IF 3.2) Pub Date : 2024-02-24 Christina E. M. Voorter, Mathijs Groeneweg, Timo I. Olieslagers, Ingrid Fae, Gottfried F. Fischer, Marco Andreani, Maria Troiano, Blanka Vidan-Jeras, Sendi Montanic, Bouke G. Hepkema, Laura B. Bungener, Marcel G. J. Tilanus, Lotte Wieten
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Concise review: The heterogenous roles of BATF3 in cancer oncogenesis and dendritic cells and T cells differentiation and function considering the importance of BATF3-dependent dendritic cells Immunogenetics (IF 3.2) Pub Date : 2024-02-15 Reza Dabbaghipour, Elham Ahmadi, Mona Entezam, Omid Rahbar Farzam, Sepideh Sohrabi, Sajjad Jamali, Ali Saber Sichani, Hadi Paydar, Behzad Baradaran
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Regulation of genes involved in the metabolic adaptation of murine microglial cells in response to elevated HIF-1α mediated activation Immunogenetics (IF 3.2) Pub Date : 2024-02-08
Abstract Microglia cells are activated in response to different stress signals. Several metabolic adaptations underlie microglia activation in the brain. Among these, in conditions like ischemic stroke and, hypoxic stress stimuli activate microglia cells. Hypoxic stress is mediated by HIF-1α. Although HIF-1α has been implicated in the alteration of metabolic pathways, changes in microglia lipid metabolism
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Determination for KIR genotype and allele copy number via real-time quantitative PCR method Immunogenetics (IF 3.2) Pub Date : 2024-01-11 Sudan Tao, Xuan You, Jielin Wang, Wei Zhang, Ji He, Faming Zhu
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Costimulatory receptors in the channel catfish: CD28 family members and their ligands Immunogenetics (IF 3.2) Pub Date : 2024-01-10 Sylvie M. A. Quiniou, Eva Bengtén, Pierre Boudinot
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The impact of long COVID on health-related quality of life in patients 6 months after discharge with severe COVID-19 Immunogenetics (IF 3.2) Pub Date : 2023-12-27 Seyedeh Mahdieh Namayandeh, Moslem Basti, Sara Jambarsang, Seyed Mojtaba Yassini Ardekani
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Patterns of evolution in MHC class II DQA and DQB exon 2 genes of Alpine mountain hares, Lepus timidus varronis, and sympatric and parapatric brown hares, L. europaeus, from Switzerland Immunogenetics (IF 3.2) Pub Date : 2023-12-20 A. Awadi, H. Ben Slimen, S. Smith, M. Makni, F. Suchentrunk
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The COVID-19 inflammation and high mortality mechanism trigger Immunogenetics (IF 3.2) Pub Date : 2023-12-08 Samuel Stróż, Piotr Kosiorek, Anna Stasiak-Barmuta
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A novel missense mutation in the AIRE gene underlying autoimmune polyglandular syndrome type 1 Immunogenetics (IF 3.2) Pub Date : 2023-11-30 Susana Vitozzi, Silvia Graciela Correa, Alejandro Lozano, Eduardo Jorge Fernández, Rodrigo Quiroga
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Investigating associations between HLA DQA1 ~ DQB1 haplotypes, H. pylori infection, metaplasia, and anti-CagA IgA seropositivity in a Turkish gastritis cohort Immunogenetics (IF 3.2) Pub Date : 2023-11-18 Mukaddes Colakogullari, Lokman Karatas, Zeynep Tatar
Helicobacter pylori was reported as an important cause of gastritis, and gastric ulcers and CagA oncoprotein-producing H. pylori subgroups were blamed to increase the severity of gastritis. Disparities were reported in that the presence of serum anti-CagA IgA was not parallel with CagA-positive H. pylori cohabitation. We hypothesized that the HLA-DQA1 ~ DQB1 haplotypes in human populations include
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Immunogenetics, sylvatic plague and its vectors: insights from the pathogen reservoir Mastomys natalensis in Tanzania Immunogenetics (IF 3.2) Pub Date : 2023-10-19 Lavinia Haikukutu, Japhet R. Lyaku, Charles M. Lyimo, Seth J. Eiseb, Rhodes H. Makundi, Ayodeji Olayemi, Kerstin Wilhelm, Nadine Müller-Klein, Dominik W. Schmid, Ramona Fleischer, Simone Sommer
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Macroevolution of avian T cell receptor C segments using genomic data Immunogenetics (IF 3.2) Pub Date : 2023-10-07 Chunhong Liang, Lin Sun, Ying Zhu, Ayong Zhao, Hongyi Liu, Ke He
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The KIR2DL1 intermediate upstream element participates in gene activation Immunogenetics (IF 3.2) Pub Date : 2023-10-06 Paul W. Wright, Hongchuan Li, Md Ahasanur Rahman, Erik M. Anderson, Megan Karwan, Jeffrey Carrell, Stephen K. Anderson
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Comparative genomics of the T cell receptor μ locus in marsupials and monotremes Immunogenetics (IF 3.2) Pub Date : 2023-09-25 K. A. Morrissey, M. R. Stammnitz, E. Murchison, R. D. Miller
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Genomic view of the origins of cell-mediated immunity Immunogenetics (IF 3.2) Pub Date : 2023-09-22 Morgan E. Janes, Allison Kinlein, Martin F. Flajnik, Louis Du Pasquier, Yuko Ohta
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Correlation between human leukocyte antigen ligands and killer cell immunoglobulin-like receptors in aplastic anemia patients from Shaanxi Han Immunogenetics (IF 3.2) Pub Date : 2023-08-17 Tianju Wang, Jun Qi, Manni Wang, Hua Xu, Junhua Wu, Lixia Shang, Le Chen, Yuhui Li
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Ancient fish lineages illuminate toll-like receptor diversification in early vertebrate evolution Immunogenetics (IF 3.2) Pub Date : 2023-08-09 Kara B. Carlson, Cameron Nguyen, Dustin J. Wcisel, Jeffrey A. Yoder, Alex Dornburg
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Increased circulating Th17 cell populations in patients with pancreatic ductal adenocarcinoma Immunogenetics (IF 3.2) Pub Date : 2023-08-04 Imteyaz Ahmad Khan, Nidhi Singh, Deepak Gunjan, Srikant Gopi, Nihar Ranjan Dash, Surabhi Gupta, Anoop Saraya
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Prof. Dr. Jan Klein (1936-2023) Immunogenetics (IF 3.2) Pub Date : 2023-08-01 Ronald Bontrop, Martin Flajnik, Colm S. O’Huigin, Masanori Kasahara
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Factors regulating the differences in frequency of infiltration of Th17 and Treg of the blood–brain barrier Immunogenetics (IF 3.2) Pub Date : 2023-07-11 Norwin Kubick, Marzena Lazarczyk, Nina Strzałkowska, Anna Charuta, Jarosław Olav Horbańczuk, Mariusz Sacharczuk, Michel Edwar Mickael
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The minor chicken class I gene BF1 is deleted between short imperfect direct repeats in the B14 and typical B15 major histocompatibility complex (MHC) haplotypes Immunogenetics (IF 3.2) Pub Date : 2023-07-05 Nicolas I. E. Rocos, Felicity J. Coulter, Thomas C. J. Tan, Jim Kaufman
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Dysregulated PD-L2 is correlated with disease activity and inflammation in rheumatoid arthritis Immunogenetics (IF 3.2) Pub Date : 2023-07-05 Jian Xiong, Jie Yang, Yuling Sun, Yachun Chen, Yundi Guo, Cuiping Liu, Jing Sun
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Prognostic value of the WT-1 gene combined with recurrent cytogenetic genes in acute myeloid leukemia Immunogenetics (IF 3.2) Pub Date : 2023-06-22 Qing Zhang, Linlin Liu, Haotian Yan, Xiyang Ren, Mei Zhou, Shudao Xiong, Huiping Wang, Qianshan Tao, Zhimin Zhai
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Complement component C1q is an immunological rheostat that regulates Fc:Fc $$\gamma$$ R interactions Immunogenetics (IF 3.2) Pub Date : 2023-06-15 Edward C. So, Hua Zhou, Ariana Greenwell, Erin E. Burch, Yaping Ji, Emmanuel Y. Mérigeon, Henrik S. Olsen, Søren M. Bentzen, David S. Block, Xiaoyu Zhang, Scott E. Strome
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Immunological assessment of a patient with Omenn syndrome resulting from compound heterozygous mutations in the RAG1 gene Immunogenetics (IF 3.2) Pub Date : 2023-06-03 Wenjun Mou, Zixin Yang, Xiaojiao Wang, Mingyan Hei, Yajuan Wang, Jingang Gui
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Evaluation of miRNA-16–2-3P, miRNA-618 levels and their diagnostic and prognostic value in the regulation of immune response during SARS Cov-2 infection Immunogenetics (IF 3.2) Pub Date : 2023-05-24 Nourelhoda E. Hassan, Walaa A. Moselhy, Ehab B. Eldomany, Emad Farah Mohamad Kholef
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Immunogenetics special issue 2023: Immunogenetics of infectious disease. Immunogenetics (IF 3.2) Pub Date : 2023-06-01 Paul J Norman
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Germline-enforced enrichment for charged amino acids in TCR beta chain (TCRβ) complementarity determining region 3 (CDR-B3) alters T cell development, repertoire content, and antigen recognition Immunogenetics (IF 3.2) Pub Date : 2023-04-29 Michael Levinson, Mohamed Khass, Peter D. Burrows, Harry W Schroeder
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Evolution of immunogenetic components encoding ultralong CDR H3 Immunogenetics (IF 3.2) Pub Date : 2023-04-21 Jeannine A. Ott, Christian Mitchell, Morgan Sheppard, Thad C. Deiss, J. M. Cody Horton, Jeremy K. Haakenson, Ruiqi Huang, Abigail R. Kelley, Brian W. Davis, James N. Derr, Vaughn V. Smider, Michael F. Criscitiello
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Impact of high human genetic diversity in Africa on immunogenicity and efficacy of RTS,S/AS01 vaccine Immunogenetics (IF 3.2) Pub Date : 2023-04-21 Stephen Tukwasibwe, Gerald Mboowa, Ivan Sserwadda, Joaniter I. Nankabirwa, Emmanuel Arinaitwe, Isaac Ssewanyana, Yoweri Taremwa, Gerald Tumusiime, Moses R. Kamya, Prasanna Jagannathan, Annettee Nakimuli
In modern medicine, vaccination is one of the most effective public health strategies to prevent infectious diseases. Indisputably, vaccines have saved millions of lives by reducing the burden of many serious infections such as polio, tuberculosis, measles, pneumonia, and tetanus. Despite the recent recommendation by the World Health Organization (WHO) to roll out RTS,S/AS01, this malaria vaccine still
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Characterization and genetic diversity of MHC class II DRB genes in the Arabian camel (Camelus dromedarius) Immunogenetics (IF 3.2) Pub Date : 2023-04-04 Mohamed Habib Yahyaoui
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Tumor necrosis factor-α induces proliferation and reduces apoptosis of colorectal cancer cells through STAT3 activation Immunogenetics (IF 3.2) Pub Date : 2023-03-18 Wei Wei, Juanhong Wang, Pu Huang, Siqi Gou, Daihua Yu, Lei Zong
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The + 3010/C single nucleotide polymorphism (rs1710) at the HLA-G 3′ untranslated region is associated with a short transcript exhibiting a deletion of 92 nucleotides Immunogenetics (IF 3.2) Pub Date : 2023-03-07 Erick C. Castelli, Gabriela Sato Paes, Isabelle Mira da Silva, Philippe Moreau, Eduardo A. Donadi
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Correction to: The immunogenetics of COVID-19. Immunogenetics (IF 3.2) Pub Date : 2023-06-01 Anshika Srivastava,Jill A Hollenbach
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Expression analysis of Carassius auratus-leukocyte-immune-type receptors (CaLITRs) during goldfish kidney macrophage development and in activated kidney leukocyte cultures Immunogenetics (IF 3.2) Pub Date : 2023-02-18 Jiahui Wang, Amro M. Soliman, Jeff Norlin, Daniel R. Barreda, James L. Stafford
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Role of T cells in severe COVID-19 disease, protection, and long term immunity Immunogenetics (IF 3.2) Pub Date : 2023-02-08 Julia Maret Hermens, Can Kesmir
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Evolution of SARS-CoV-2-specific CD4+ T cell epitopes Immunogenetics (IF 3.2) Pub Date : 2023-01-31 Marina Brand, Can Keşmir
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Innate receptors modulating adaptive T cell responses: KIR-HLA interactions and T cell-mediated control of chronic viral infections Immunogenetics (IF 3.2) Pub Date : 2023-01-31 Laura Mora-Bitria, Becca Asquith
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Comparison between qPCR and RNA-seq reveals challenges of quantifying HLA expression Immunogenetics (IF 3.2) Pub Date : 2023-01-28 Vitor R. C. Aguiar, Erick C. Castelli, Richard M. Single, Arman Bashirova, Veron Ramsuran, Smita Kulkarni, Danillo G. Augusto, Maureen P. Martin, Maria Gutierrez-Arcelus, Mary Carrington, Diogo Meyer
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The impact of HLA polymorphism on herpesvirus infection and disease Immunogenetics (IF 3.2) Pub Date : 2023-01-03 William H. Palmer, Paul J. Norman
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Assessment of regulatory T cells (Tregs) and Foxp3 methylation level in chronic myeloid leukemia patients on tyrosine kinase inhibitor therapy Immunogenetics (IF 3.2) Pub Date : 2022-12-26 Shahla’a Fadhil Sabir, Bassam Francis Matti, Wifaq Mahmood Ali Alwatar
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The immunogenetics of COVID-19 Immunogenetics (IF 3.2) Pub Date : 2022-12-19 Jill A. Hollenbach, Anshika Srivastava
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The immunogenetics of tuberculosis (TB) susceptibility Immunogenetics (IF 3.2) Pub Date : 2022-12-13 Carene Anne Alene Ndong Sima, Dayna Smith, Desiree C. Petersen, Haiko Schurz, Caitlin Uren, Marlo Möller
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The antigen recognition portion of African buffalo class I MHC is highly polymorphic, consistent with a complex pathogen challenge environment, and the 3’ region suggests distinct haplotype configurations Immunogenetics (IF 3.2) Pub Date : 2022-12-13 Isaiah Obara, Ard Nijhof, Patrick Atimnedi, Domnic Mijele, Anne Nanteza, Khawla Elati, Richard Bishop
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Unfavorable immunotherapy plus tyrosine kinase inhibition outcome of metastatic renal cell carcinoma after radical nephrectomy with increased ADAM9 expression Immunogenetics (IF 3.2) Pub Date : 2022-12-14 Xianglai Xu, Ying Wang, Zhaoyi Chen, Yanjun Zhu, Jiajun Wang, Jianming Guo
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X-linked hyper-immunoglobulin M syndrome harboring a novel CD40-ligand gene mutation: a case report Immunogenetics (IF 3.2) Pub Date : 2022-12-07 Rahul Ramachandran, Yamini Krishnan, Parminder Singh, Ashok Kumar, Abhishek Mohanty
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Bioinformatics analysis of structural protein to approach a vaccine candidate against Vibrio cholerae infection Immunogenetics (IF 3.2) Pub Date : 2022-12-02 Elijah Kolawole Oladipo, Olawumi Elizabeth Akindiya, Glory Jesudara Oluwasanya, Gideon Mayowa Akanbi, Seun Elijah Olufemi, Daniel Adewole Adediran, Favour Oluwadara Bamigboye, Rasidat Oyindamola Aremu, Kehinde Temitope Kolapo, Jerry Ayobami Oluwasegun, Hezekiah Oluwajoba Awobiyi, Esther Moradeyo Jimah, Boluwatife Ayobami Irewolede, Elizabeth Oluwatoyin Folakanmi, Odunola Abimbola Olubodun, Samuel Adebowale
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Distinct frequency patterns of LILRB3 and LILRA6 allelic variants in Europeans Immunogenetics (IF 3.2) Pub Date : 2022-11-30 Arman A. Bashirova, Wojciech Kasprzak, Colm O’hUigin, Mary Carrington
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Age-dependent effect of the IFIH1/MDA5 gene variants on the risk of critical COVID-19 Immunogenetics (IF 3.2) Pub Date : 2022-11-25 María G. Muñiz-Banciella, Guillermo M. Albaiceta, Laura Amado-Rodríguez, Estefanía Salgado del Riego, Inés López Alonso, Cecilia López-Martínez, Paula Martín-Vicente, Marta García-Clemente, Tamara Hermida-Valverde, Ana I. Enríquez-Rodriguez, Cristina Hernández-González, Elías Cuesta-Llavona, Victoria Alvarez, Juan Gómez, Eliecer Coto
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HLA-G expression in Merkel cell carcinoma and the correlation with Merkel cell polyomavirus infection Immunogenetics (IF 3.2) Pub Date : 2022-10-14 L. M. Parra, B. G. C. Sartori, D. R. Fernandes, L. R. V. Fachin, M. R. S. Nogueira, A. F. F. Belone, A. J. F. Nunes, F. C. Souza-Santana
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Genetic variation of glycophorins and infectious disease Immunogenetics (IF 3.2) Pub Date : 2022-10-12 Edward J. Hollox, Sandra Louzada
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Whole exome sequencing identified a novel splice donor site variant in interleukin 2 receptor alpha chain Immunogenetics (IF 3.2) Pub Date : 2022-10-04 Nadia Waheed, Maryam Naseer, Nighat Haider, Sufyan Suleman, Asmat Ullah
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SNHG3 regulates NEIL3 via transcription factor E2F1 to mediate malignant proliferation of hepatocellular carcinoma Immunogenetics (IF 3.2) Pub Date : 2022-09-17 Fabiao Zhang, Jie Lu, Jian Yang, Qiqiang Dai, Xuefeng Du, Yongfu Xu, Caiming Zhang
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Mutated Pkhd1 alone is sufficient to cause autoimmune biliary disease on the nonobese diabetic (NOD) genetic background Immunogenetics (IF 3.2) Pub Date : 2022-09-13 David E. Adams, Luke S. Heuer, Manuel Rojas, Weici Zhang, William M. Ridgway
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IL4I1 enhances PD-L1 expression through JAK/STAT signaling pathway in lung adenocarcinoma Immunogenetics (IF 3.2) Pub Date : 2022-09-03 Jiefei Zhu, Yan Li, Xu Lv
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Functional consequences of allotypic polymorphisms in human immunoglobulin G subclasses Immunogenetics (IF 3.2) Pub Date : 2022-07-29 Andrew R. Crowley, Simone I. Richardson, Marina Tuyishime, Madeleine Jennewein, Meredith J. Bailey, Jiwon Lee, Galit Alter, Guido Ferrari, Lynn Morris, Margaret E. Ackerman