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Characterizing identity by descent segments in Chinese interpopulation unrelated individual pairs Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-03-18 Qiqi Ji, Yining Yao, Zhimin Li, Zhihan Zhou, Jinglei Qian, Qiqun Tang, Jianhui Xie
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Pancreatitis affects gut microbiota via metabolites and inflammatory cytokines: an exploratory two-step Mendelian randomisation study Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-03-16
Abstract Previous studies have observed relationships between pancreatitis and gut microbiota; however, specific changes in gut microbiota abundance and underlying mechanisms in pancreatitis remain unknown. Metabolites are important for gut microbiota to fulfil their biological functions, and changes in the metabolic and immune environments are closely linked to changes in microbiota abundance. We
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Deleterious variant in FAM71D cause male infertility with asthenoteratospermia Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-03-15 Xiaobin Zhu, Liu Liu, Shixiong Tian, Guijun Zhao, Erlei Zhi, Qian Chen, Feng Zhang, Aijun Zhang, Shuyan Tang, Chunyu Liu
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Bridging drug discovery through hierarchical subtractive genomics against asd, trpG, and secY of pneumonia causing MDR Staphylococcus aureus Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-03-13 Ayesha Wisal, Nida Saeed, Muhammad Aurongzeb, Muhammad Shafique, Saman Sohail, Waheed Anwar, Zarrin Basharat, Muhammad Irfan, Asad Ullah, Syed S. Hassan
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Characterization of a novel heterozygous frameshift variant in NDP gene that causes familial exudative vitreoretinopathy in female patients Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-03-13 Mu Yang, Li Peng, Liting Lv, Erkuan Dai, Yunqi He, Rulian Zhao, Shujin Li
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Mesenchymal stem cells-derived exosomes carrying microRNA-30b confer protection against pulmonary fibrosis by downregulating Runx1 via Spred2 Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-03-13
Abstract Idiopathic pulmonary fibrosis (IPF) is a chronic pulmonary fibrosis disease that is fatal. Mesenchymal stem cells (MSCs)-secreted exosomes (exos) have been linked to improving PF. Moreover, exosomal microRNAs (miRs) can control the growth of numerous diseases, including lung disorders. Our bioinformatics analysis showed that miR-30b was downregulated in tissue samples from surgical remnants
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A genome-wide association study for resistance to Fusarium wilt (Fusarium oxysporum f. sp. vasinfectum) race 4 in diploid cotton (Gossypium arboreum) and resistance transfer to tetraploid Gossypium hirsutum Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-03-13 Abdelraheem Abdelraheem, Yi Zhu, Linghe Zeng, Salliana Stetina, Jinfa Zhang
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Comparative genomics of four lactic acid bacteria identified with Vitek MS (MALDI-TOF) and whole-genome sequencing Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-03-13 Özge Kahraman-Ilıkkan
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Comparative genomic analysis of Pseudomonas aeruginosa strains susceptible and resistant to carbapenems and aztreonam isolated from patients with healthcare-associated infections in a Mexican hospital Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-03-12 María José Martínez-Gallardo, Claudia Villicaña, Martha Yocupicio-Monroy, Sofía Lizeth Alcaraz-Estrada, Juana Salazar-Salinas, Omar Fernando Mendoza-Vázquez, Gabriel Damazo-Hernández, Josefina León-Félix
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Serpentine environment prevails over geographic distribution in shaping the genetic diversity of Medicago lupulina L. Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-03-12 Anesa Ahatović Hajro, Mujo Hasanović, Senad Murtić, Abdurahim Kalajdžić, Naris Pojskić, Adaleta Durmić-Pašić
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Primer extension refractory PCR: an efficient and reliable genome walking method Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-03-11 Haixing Li, Zhiyu Lin, Xinyue Guo, Zhenkang Pan, Hao Pan, Dongying Wang
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A rapid, inexpensive and effective method for the efficient isolation of genomic DNA from Gram-negative bacteria Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-03-07 Lihini Ranesha Weerakkody, Chamindri Witharana
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Predicting genetic risk factors for AA amyloidosis in Algerian patients with familial Mediterranean fever Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-03-07 Djouher Ait-Idir, Bahia Djerdjouri, Khaled Latreche, Rawda Sari-Hamidou, Ghalia Khellaf
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Genomics-based analysis of four porcine-derived lactic acid bacteria strains and their evaluation as potential probiotics Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-03-05 Dekai Niu, Ni Feng, Siteng Xi, Jianjian Xu, Yong Su
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C and G are frequently mutated into T and A in coding regions of human genes Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-03-02 Yong Wang, Ke-Ping Chen
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Genome-wide association study of drought tolerance in wheat (Triticum aestivum L.) identifies SNP markers and candidate genes Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-03-02 Sina Nouraei, Md Sultan Mia, Hui Liu, Neil C. Turner, Guijun Yan
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Introduction of a diverse genetic background of Pyrus into Malus through intergeneric hybridization Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-03-02 Takuya Morimoto, Ryuya Narazaki, Hiroaki Okabe, Lumin Zhang, Kazusa Nishimura, Akihiro Itai
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Identification of plb1 mutation that extends longevity via activating Sty1 MAPK in Schizosaccharomyces pombe Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-02-29
Abstract To understand the lifespan of higher organisms, including humans, it is important to understand lifespan at the cellular level as a prerequisite. So, fission yeast is a good model organism for the study of lifespan. To identify the novel factors involved in longevity, we are conducting a large-scale screening of long-lived mutant strains that extend chronological lifespan (cell survival in
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Novel MEI1 mutations cause chromosomal and DNA methylation abnormalities leading to embryonic arrest and implantation failure Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-02-28 Xiangli Wu, Yuqing Tian, Yiqi Yu, Xujun He, Xiaohua Tang, Shishi Li, Jing Shu, Xiaoyan Guo
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The GaKAN2, a KANADI transcription factor, modulates stem trichomes in Gossypium arboreum Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-02-28 Xujiao Ren, Luying Yang, Yasir Muhammad, Yuxing Xie, Xinyi Lin, Li Yu, Yuefen Cao, Mingquan Ding, Yurong Jiang, Junkang Rong
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Characterization of barley (Horduem vulgare) lys3 mutants identifies genes under the regulation of the prolamin-box binding transcription factor and elucidates its role in endosperm promoter methylation during grain development Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-02-28
Abstract Barley ranks fourth in global cereal production and is primarily grown for animal feed and malt. Hordeins, the principal barley seed storage proteins, are homologous to wheat gluten and when ingested elicit an immune response in people with Coeliac disease. Risø 1508 is a chemically induced barley mutant with low hordein levels imparted by the lys3.a locus that is reported to be caused by
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Growth performance, lipid metabolism, and systemic immunity of weaned piglets were altered by buckwheat protein through the modulation of gut microbiota Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-02-27 Weilong Tu, Wansen Nie, Xiaohui Yao, Junjie Zhang, Hailong Zhang, Di Di, Zongjie Li
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De novo assembly of the complete mitochondrial genome of Mycetophylax simplex Emery, 1888 through organelle targeting revels no substantial expansion of gene spacers, but rather some slightly shorter genes Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-02-27
Abstract Mitochondria play a key role in cell biology and have their own genome, residing in a highly oxidative environment that induces faster changes than the nuclear genome. Because of this, mitochondrial markers have been exploited to reconstruct phylogenetic and phylogeographic relationships in studies of adaptation and molecular evolution. In this study, we determined the complete mitogenome
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Tomatidine activates autophagy to improve lung injury and inflammation in sepsis by inhibiting NF-κB and MAPK pathways Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-02-24 Bo Xu, Min Huang, Hang Qi, Hongzhou Xu, Liang Cai
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Mechanism underlying the rapid growth of Phalaenopsis equestris induced by 60Co-γ-ray irradiation Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-02-23 Yang Meng, Wei Li, Yunxiao Guan, Zihan Song, Guoren He, Donghui Peng, Feng Ming
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The effect of missing data on evolutionary analysis of sequence capture bycatch, with application to an agricultural pest Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-02-21 Leo A. Featherstone, Angela McGaughran
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Identification and mechanism determination of the efflux pump subunit amrB gene mutations linked to gentamicin susceptibility in clinical Burkholderia pseudomallei from Malaysian Borneo Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-02-21
Abstract The bacterium Burkholderia pseudomallei is typically resistant to gentamicin but rare susceptible strains have been isolated in certain regions, such as Thailand and Sarawak, Malaysia. Recently, several amino acid substitutions have been reported in the amrB gene (a subunit of the amrAB-oprA efflux pump gene) that confer gentamicin susceptibility. However, information regarding the mechanism
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miRNAs are involved in regulating the formation of recovery tissues in virus infected Nicotiana tabacum Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-02-20 Jingya Zhou, Hongyan Han, Sucen Liu, Chenglong Ji, Bolei Jiao, Yiting Yang, Dehui Xi
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Population genetic analyses of Eastern Chinese Han nationality using ForenSeq™ DNA Signature Prep Kit Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-02-20
Abstract Currently, the most commonly used method for human identification and kinship analysis in forensic genetics is the detection of length polymorphism in short tandem repeats (STRs) using polymerase chain reaction (PCR) and capillary electrophoresis (CE). However, numerous studies have shown that considerable sequence variations exist in the repeat and flanking regions of the STR loci, which
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Genetic evidence for a single founding population of the Lakshadweep Islands Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-02-19 Sachin Kumar, Prajjval Pratap Singh, Nagarjuna Pasupuleti, Shivanand S. Shendre, Jaison Jeevan Sequeira, Idrees Babu, Mohammed S. Mutak, Niraj Rai, Gyaneshwer Chaubey
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Assessing sequence variation, haplotype analysis and molecular characterisation of aspartate kinase2 (ask2) gene regulating methionine biosynthesis in diverse maize inbreds Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-02-13 Hriipulou Duo, Rashmi Chhabra, Vignesh Muthusamy, Rajkumar U. Zunjare, Firoz Hossain
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CRISPR/Cas9-mediated efficient white genome editing in the black soldier fly Hermetia illucens Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-02-05 Zhuoxiao Sui, Qi Wu, Jin Geng, Jinhua Xiao, Dawei Huang
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Four classic “de novo” genes all have plausible homologs and likely evolved from retro-duplicated or pseudogenic sequences Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-02-05 Joseph Hannon Bozorgmehr
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Super enhancer loci of EGFR regulate EGFR variant 8 through enhancer RNA and strongly associate with survival in HNSCCs Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-01-18 Sundaram Reddy Chakkarappan, Karuppiah Vijayamuthuramalingam Umadharshini, Shankar Dhamodharan, Mathew Maria Rose, Govindasamy Gopu, Avaniyapuram Kannan Murugan, Ituro Inoue, Arasambattu Kannan Munirajan
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Genome-wide identification of the key Kinesin genes during fiber and boll development in upland cotton (Gossypium hirsutum L) Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-01-11 Hong Zhu, Jianzhong Xu, Kanbing Yu, Jianfei Wu, Huifang Xu, Shubin Wang, Tianwang Wen
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Liver cancer-specific mutations in functional domains of ADAR2 lead to the elevation of coding and non-coding RNA editing in multiple tumor-related genes Mol. Genet. Genomics (IF 3.1) Pub Date : 2024-01-03 Jian Li, Chaowei Li, Wengui Xu
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Development and validation of allele-specific PCR-based SNP typing in a gene on chromosome D03 conferring resistance to Fusarium wilt race 4 in Upland cotton (Gossypium hirsutum) Mol. Genet. Genomics (IF 3.1) Pub Date : 2023-11-04 Jinfa Zhang, Yi Zhu, Terry Wheeler, Jane K. Dever
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Advances in understanding effects of miRNAs on apoptosis, autophagy, and pyroptosis in knee osteoarthritis Mol. Genet. Genomics (IF 3.1) Pub Date : 2023-11-02 Fangyu An, Bai Sun, Ying Liu, Chunmei Wang, Xiaxia Wang, Jiayu Wang, Yongqi Liu, Chunlu Yan
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Identification and expression analysis of the KNOX genes during organogenesis and stress responseness in Camellia sinensis (L.) O. Kuntze Mol. Genet. Genomics (IF 3.1) Pub Date : 2023-11-03 Hongwei Dai, Shuting Zheng, Cheng Zhang, Rui Huang, Lianyu Yuan, Huarong Tong
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Low LdMYB12 expression contributes to petal spot deficiency in Lilium davidii var. unicolor Mol. Genet. Genomics (IF 3.1) Pub Date : 2023-11-01 Xinqi Zhang, Sujuan Xu, Xue Pan, Ze Wu, Liping Ding, Nianjun Teng
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Correction: Optimization of a 2A self-cleaving peptide-based multigene expression system for efficient expression of upstream and downstream genes in silkworm Mol. Genet. Genomics (IF 3.1) Pub Date : 2023-10-21 Yuancheng Wang, Feng Wang, Sheng Xu, Riyuan Wang, Wenjing Chen, Kai Hou, Chi Tian, Fan Wang, Ping Zhao, Qingyou Xia
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Exploring homologous recombination repair and base excision repair pathway genes for possible diagnostic markers in hematologic malignancies Mol. Genet. Genomics (IF 3.1) Pub Date : 2023-10-20 Sumaira Fida Abbasi, Ishrat Mahjabeen, Neelam Parveen, Imama Qamar, Maria Fazal Ul Haq, Rabia Shafique, Nadia Saeed, Nida Sarosh Ashraf, Mahmood Akhtar Kayani
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Assessing the causal relationship between immune traits and systemic lupus erythematosus by bi-directional Mendelian randomization analysis Mol. Genet. Genomics (IF 3.1) Pub Date : 2023-10-16 Jie Gu, Guan-Min Yan, Xiao-Lin Kong, Yin-Ying Zhang, Li-Hong Huang, Hui-Min Lu
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Suppression of the dwarf phenotype of an Arabidopsis mutant defective in thermospermine biosynthesis by a synonymous codon change in the SAC51 uORF Mol. Genet. Genomics (IF 3.1) Pub Date : 2023-10-16 Yuichi Nishii, Daiki Koyama, Hiroko Fukushima, Taku Takahashi
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Single- and multi-trait genomic prediction and genome-wide association analysis of grain yield and micronutrient-related traits in ICARDA wheat under drought environment Mol. Genet. Genomics (IF 3.1) Pub Date : 2023-10-18 Wuletaw Tadesse, Zakaria El Gataa, Fatima Ezzahra Rachdad, Adil El Baouchi, Zakaria Kehel, Admas Alemu
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Ginsenoside Rh4 inhibits inflammation-related hepatocellular carcinoma progression by targeting HDAC4/IL-6/STAT3 signaling Mol. Genet. Genomics (IF 3.1) Pub Date : 2023-10-16 Ruiyuan Jiang, Shujuan Luo, Meng Zhang, Wei Wang, Shaoyuan Zhuo, Yajing Wu, Qingmei Qiu, Yuan Yuan, Xiao Jiang
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The maternal ancestry of the Kavaratti islanders and the last glacial maximum aftermath Mol. Genet. Genomics (IF 3.1) Pub Date : 2023-10-12 Alnoman Mundher Tayyeh, Jaison Jeevan Sequeira, Lomous Kumar, Idrees Babu, George van Driem, Mohammed Shafiul Mustak
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Whole-genome sequence and mass spectrometry study of the snow blight fungus Phacidium infestans (Karsten) DSM 5139 growing at freezing temperatures Mol. Genet. Genomics (IF 3.1) Pub Date : 2023-10-10 C. Zerouki, K. Chakraborty, S. Kuittinen, A. Pappinen, O. Turunen
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Development of an SNP marker set for marker-assisted backcrossing using genotyping-by-sequencing in tetraploid perilla Mol. Genet. Genomics (IF 3.1) Pub Date : 2023-09-19 Jae-Eun Oh, Ji-Eun Kim, Jangmi Kim, Myoung-Hee Lee, Keunpyo Lee, Tae-Ho Kim, Sung-Hwan Jo, Jeong-Hee Lee
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The genome of Anoplarchus purpurescens (Stichaeidae) reflects its carnivorous diet Mol. Genet. Genomics (IF 3.1) Pub Date : 2023-09-10 Ninh Le, Joseph Heras, Michelle J. Herrera, Donovan P. German, Lisa T. Crummett
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Correction: Optimization of a 2A self-cleaving peptide-based multigene expression system for efficient expression of upstream and downstream genes in silkworm Mol. Genet. Genomics (IF 3.1) Pub Date : 2023-09-12 Yuancheng Wang, Feng Wang, Sheng Xu, Riyuan Wang, Wenjing Chen, Kai Hou, Chi Tian, Fan Wang, Ping Zhao, Qingyou Xia
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Characterization and diversity of CRISPR/Cas systems in Klebsiella oxytoca Mol. Genet. Genomics (IF 3.1) Pub Date : 2023-09-08 Jiaxue Zhao, Yanyan Xi, Jiangfeng Zhang, Yuefei Jin, Haiyan Yang, Guangcai Duan, Shuaiyin Chen, Jinzhao Long
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Sequence variations associated with novel purple-pericarp super-sweetcorn compared to its purple-pericarp maize and white super-sweetcorn parents Mol. Genet. Genomics (IF 3.1) Pub Date : 2023-09-08 Apurba Anirban, Ardashir Kharabian Masouleh, Robert J. Henry, Tim J. O’Hare
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Maternal uniparental disomy of chromosome 21 as a cause of pseudo-exclusion from paternity Mol. Genet. Genomics (IF 3.1) Pub Date : 2023-09-01 Andrei Semikhodskii, Tatiana Makarova, Daria Sutyagina
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Annotation of transposable elements in the transcriptome of the Neotropical brown stink bug Euschistus heros and its chromosomal distribution Mol. Genet. Genomics (IF 3.1) Pub Date : 2023-08-30 Jaqueline Fernanda Dionisio, Larissa Forim Pezenti, Rogério Fernandes de Souza, Daniel Ricardo Sosa-Gómez, Renata da Rosa
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Genomic region and origin for selected traits during differentiation of small-fruit cultivars in Japanese apricot (Prunus mume) Mol. Genet. Genomics (IF 3.1) Pub Date : 2023-08-26 Koji Numaguchi, Yuto Kitamura, Tomoaki Kashiwamoto, Takuya Morimoto, Takaaki Oe
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Acyl CoA oxidase: from its expression, structure, folding, and import to its role in human health and disease Mol. Genet. Genomics (IF 3.1) Pub Date : 2023-08-09 Isha Kashyap, Rachayeeta Deb, Abhigna Battineni, Shirisha Nagotu
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HEATR3 involved in the cell proliferation, metastasis and cell cycle development of bladder cancer acts as a tumor suppressor Mol. Genet. Genomics (IF 3.1) Pub Date : 2023-07-31 Xia Dou, Xiaoya Ma, Wenting Meng, Wenjie Zhang, Shuangyu Yang, Fanglin Niu, Yuyan Xiong, Tianbo Jin
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Primary open-angle glaucoma risk prediction with ABCA1 and LOC102723944 variants and their genotype–phenotype correlations in southern Chinese population Mol. Genet. Genomics (IF 3.1) Pub Date : 2023-07-29 Zhenggen Wu, Chukai Huang, Yuqian Zheng, Xiang-Ling Yuan, Shaowan Chen, Yanxuan Xu, Li Jia Chen, Chi Pui Pang, Mingzhi Zhang, Tsz Kin Ng
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Identification of potential genetic causal variants for obesity-related traits using statistical fine mapping Mol. Genet. Genomics (IF 3.1) Pub Date : 2023-07-27 Rui Gong, Jonathan Greenbaum, Xu Lin, Yan Du, Kuan-Jui Su, Yun Gong, Jie Shen, Hong-Wen Deng