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Transcriptional regulation of the alternative sex hormone-binding globulin promoter by KLF4 Gene Expr. Patterns (IF 1.2) Pub Date : 2024-03-07 W, a, r, r, e, n, , M, ., , M, e, y, e, r, s
In most mammals the major site of sex hormone-binding globulin (SHBG) synthesis is the liver wherefrom it is secreted into the bloodstream and is the primary determinant of sex steroid access to target tissues. The minor site of SHBG synthesis is the testis and in lower mammals testicular SHBG has long been known to be synthesized and secreted by Sertoli cells. However, human testicular is expressed
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Ontogeny and tissue specific expression profiles of recombination activating genes (RAGs) during development in Nile tilapia, Oreochromisniloticus Gene Expr. Patterns (IF 1.2) Pub Date : 2024-03-07 Ravikumar M. Chovatia, Arpit Acharya, Kiran D. Rasal, Megha Kadam Bedekar, Kezhedath Jeena, R. Bharathi Rathinam, Chandana Dinakaran, Gayatri Tripathi
Recombination activating genes () mediates the process of rearrangement and somatic recombination (V(D)J) to generate different antibody repertoire. Studies on the expression pattern of adaptive immune genes during ontogenic development are crucial for the formulation of fish immunization strategy. In the present study, Nile tilapia was taken to explore the relative expression profile of genes during
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Gene expression analysis of oxidative stress-related genes in the apical, middle, and basal turns of the cochlea Gene Expr. Patterns (IF 1.2) Pub Date : 2024-03-02 Yang Yang, Xin Chen, Chaoyong Tian, Bei Fan, Xiaogang An, Zhenzhen Liu, Qiong Li, Wenjuan Mi, Ying Lin, Dingjun Zha
It can be observed from aminoglycoside-induced hair cell damage that the cochlea basal turn is more susceptible to trauma than the apex. Drug-induced hearing loss is closely related to oxidative damage. The basilar membrane directly exposed to these ototoxic drugs exhibits differences in damage, indicating that there is an inherent difference in the sensitivity to oxidative damage from the apex to
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Embryonic expression patterns of TBL1 family in zebrafish Gene Expr. Patterns (IF 1.2) Pub Date : 2024-01-23 Yuanqi Jia, Qiu Jiang, Shuna Sun
Except the addition of in human, () family mainly consists of two members and , taking part in multiple intracellular signaling pathways such as Wnt/β-catenin and NF-κB in cancer progression. However, the gene expression patterns of this family during embryonic development remain largely unknown. Here we took advantage of zebrafish model to characterize the spatial and temporal expression patterns
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Exosome complex components 1 and 2 are vital for early mammalian development Gene Expr. Patterns (IF 1.2) Pub Date : 2023-11-07 Sanjana Srinivasan, Xinjian He, Sarah Mirza, Jesse Mager
Exosome Complex Components 1 and 2 (EXOSC1 and 2) are two proteins in the RNA Exosome complex whose main function is 5’ → 3’ RNA degradation and processing. The RNA exosome complex is comprised of nine subunits that form two separate components: the S1/KH cap and the PH-core. EXOSC1 and 2 are both part of the S1/KH cap and are involved in binding nascent RNA. As part of a systemic characterization
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Developmental expression of peroxiredoxin gene family in early embryonic development of Xenopus tropicalis Gene Expr. Patterns (IF 1.2) Pub Date : 2023-10-14 Linke Zhong, Tingting Fu, Chengdong Wang, Xufeng Qi, Wai-Yee Chan, Dongqing Cai, Hui Zhao
Peroxidase genes (Prdx) encode a family of antioxidant proteins, which can protect cells from oxidative damage by reducing various cellular peroxides. This study investigated the spatiotemporal expression patterns of gene members in this family during the early development of Xenopus tropicalis. Real-time quantitative PCR showed that all members of this gene family have a distinct temporal expression
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Cell adhesion marker expression dynamics during fusion of the optic fissure Gene Expr. Patterns (IF 1.2) Pub Date : 2023-10-14 Holly Hardy, Joe Rainger
Tissue fusion is a critical process that is repeated in multiple contexts during embryonic development and shares common attributes to processes such as wound healing and metastasis. Ocular coloboma is a developmental eye disorder that presents as a physical gap in the ventral eye, and is a major cause of childhood blindness. Coloboma results from fusion failure between opposing ventral retinal epithelia
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Expression analysis of plvap in mouse heart development, homeostasis and injury Gene Expr. Patterns (IF 1.2) Pub Date : 2023-09-28 Yu Sui, Shan Kou, Kaixin Ge, Jinjun Cao, Chen Liu, Hui Zhang
Plasmalemma vesicle associated protein (PLVAP) is commonly considered to be specifically expressed in endothelial cells in which it localized to diaphragms of caveolae, fenestrae, and transendothelial channels. PLVAP is reported to be an important regulator of heart development and a novel target to promote cardiac repair in the ischemic heart. However, the dynamics of plvap expression in heart development
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Pluripotency and embryonic lineage genes expression in the presence of small molecule inhibitors of FGF, TGFβ and GSK3 during pre-implantation development of goat embryos Gene Expr. Patterns (IF 1.2) Pub Date : 2023-09-09 Mehdi Hajian, Shiva Rouhollahi Varnosfaderani, Farnoosh Jafarpour, Nima Tanhaei Vash, Mohammad Hossein Nasr-Esfahani
Generating stable livestock pluripotent stem cells (PSCs) can be used for complex genome editing, cellular agriculture, gamete generation, regenerative medicine and in vitro breeding schemes. Over the past decade, significant progress has been made in characterizing pluripotency markers for livestock species. In this study, we investigated embryo development and gene expression of the core pluripotency
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Spatiotemporal expression patterns of R-spondins and their receptors, Lgrs, in the developing mouse telencephalon Gene Expr. Patterns (IF 1.2) Pub Date : 2023-08-29 Keisuke Watanabe, Masao Horie, Manabu Hayatsu, Yoshikazu Mikami, Noboru Sato
Development of the mammalian telencephalon, which is the most complex region of the central nervous system, is precisely orchestrated by many signaling molecules. Wnt signaling derived from the cortical hem, a signaling center, is crucial for telencephalic development including cortical patterning and the induction of hippocampal development. Secreted protein R-spondin (Rspo) 1–4 and their receptors
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Corrigendum to “Comparative expression analysis of TEADs and their splice variants in mouse embryonic stem cells” [Gene Expr Patterns 47 (2022) 119302/36516960] Gene Expr. Patterns (IF 1.2) Pub Date : 2023-07-29 Yuda Cheng, Yang Xiao, Yan Ruan, Jiali Wang, Yanping Tian, Jiaxiang Xiong, Jiaqi Wang, Fengsheng Wang, Chen Zhang, Yixiao Xu, Lianlian Liu, Meng Yu, Jiangjun Wang, Binyu Zhao, Yue Zhang, Ran Yang, Yi Yang, Zhongxiang Yao, Rui Jian, Lan Xiao, Junlei Zhang
Abstract not available
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The role of mip in the development of lens in zebrafish Gene Expr. Patterns (IF 1.2) Pub Date : 2023-06-25 Mingyan He, Guangkai Zhou, Qinghong Lin, Nan Zhou
Major intrinsic protein (MIP) functions as a water channel and a cell-junction molecule in the vertebrate eye lens. The pathogenic mechanism behind the loss of MIP function in the lens, which leads to degraded optical quality and cataract formation, is still unclear. In this study, a zebrafish model with the mipb mutant was produced. The expression of mipb mRNA and protein was dramatically reduced
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CRISPR/Cas9-induced asap1a and asap1b co-knockout mutant zebrafish displayed abnormal embryonic development and impaired neutrophil migration Gene Expr. Patterns (IF 1.2) Pub Date : 2023-06-29 Cui Jia, Da Wen, Liqing Wang, Chaoqun Meng, Yuhuan Wang, Zhonghua Zhao, Changxin Wu
ASAP1 (Arf-GAP with SH3 domain, the ankyrin repeat and the PH domain) is the GTPase activating protein of the small G protein Arf. To understand more about the physiological functions of ASAP1 in vivo, we chose to use the zebrafish as an animal model, and analyzed the characterization of asap1 using loss-of-function studies. Here, two isoforms in zebrafish, asap1a and asap1b, were found to be homologous
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hnRNPL expression dynamics in the embryo and placenta Gene Expr. Patterns (IF 1.2) Pub Date : 2023-05-04 Vineetha Mathew, Ariel Mei, Hamida Giwa, Agnes Cheong, Ashmita Chander, Aaron Zou, Robert M. Blanton, Olga Kashpur, Wei Cui, Donna Slonim, Taysir Mahmoud, Perrie O'Tierney-Ginn, Jesse Mager, Isabelle Draper, Mary C. Wallingford
Heterogeneous nuclear ribonucleoprotein L (hnRNPL) is a conserved RNA binding protein (RBP) that plays an important role in the alternative splicing of gene transcripts, and thus in the generation of specific protein isoforms. Global deficiency in hnRNPL in mice results in preimplantation embryonic lethality at embryonic day (E) 3.5. To begin to understand the contribution of hnRNPL-regulated pathways
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Identification of novel candidate genes leading to sex differentiation in primordial germ cells of Drosophila Gene Expr. Patterns (IF 1.2) Pub Date : 2023-05-03 Ryoma Ota, Hiroki Miura, Masaki Masukawa, Makoto Hayashi, Satoru Kobayashi
Germline sex determination and differentiation are pivotal processes in reproduction. In Drosophila, sex determination of the germline occurs in primordial germ cells (PGCs), and the sex differentiation of these cells is initiated during embryogenesis. However, the molecular mechanism initiating sex differentiation remains elusive. To address this issue, we identified sex-biased genes using RNA-sequencing
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Gene expression analysis of the Tao kinase family of Ste20p-like map kinase kinase kinases during early embryonic development in Xenopus laevis Gene Expr. Patterns (IF 1.2) Pub Date : 2023-04-01 Michael D. Yoder, Steven Van Osten, Gregory F. Weber
Development of the vertebrate embryo requires strict coordination of a highly complex series of signaling cascades, that drive cell proliferation, differentiation, migration, and the general morphogenetic program. Members of the Map kinase signaling pathway are repeatedly required throughout development to activate the downstream effectors, ERK, p38, and JNK. Regulation of these pathways occurs at
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Transcription factor cellular promoter 2 is required for upstream binding protein 1 -mediated angiogenesis Gene Expr. Patterns (IF 1.2) Pub Date : 2023-03-06 Yanyan Ren, , Qingbo Lu, Qiang Wang, Gentao Lu, Yanli Wei, Jiaqi Zhou
Objective Angiogenesis is a key process of repairing tissue damage, and it is regulated by the delicate balance between anti-angiogenesis factors. In the present study, we investigate whether transcription factor cellular promoter 2 (TFCP2) is required for upstream binding protein 1 (UBP1)-mediated angiogenesis. Methods Levels of UBP1 and TFCP2 in human umbilical vein endothelial cells (HUVECs) are
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Fibroblast growth factor pathway component expression in the regenerating zebrafish fin Gene Expr. Patterns (IF 1.2) Pub Date : 2023-02-24 Nicole Cudak, Alejandra Cristina López-Delgado, Sebastian Keil, Franziska Knopf
Adult zebrafish regenerate their appendages (fins) after amputation including the regeneration of bone structures (fin rays). Fibroblast growth factor (Fgf) signaling, which is involved in morphogenetic processes during development, has been shown to be essential for the process of fin regeneration. Moreover, mutations in Fgf pathway component genes lead to abnormal skeletal growth in teleosts and
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Expression patterns of ABCE model genes during flower development of melon (Cucumis melo L.) Gene Expr. Patterns (IF 1.2) Pub Date : 2023-02-03 Yufan Sun, Tiantian Ren, Jiateng Zhao, Wensheng Zhao, Lanchun Nie
In production, most cultivars of melon are andromonoecious and characterized by carrying both male and bisexual flowers on the same plant. In this study, four A-class genes (CmAP1a, CmAP1b, CmAP2a and CmAP2b), two B-class genes (CmAP3 and CmPI), two C-class genes (CmAGa and CmAGb) and four E-class genes (CmSEP1,2,3,4) were identified in melon. However, no D-class gene of melon was identified. The conserved
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Searching by parts: Towards fine-grained image retrieval respecting species correlation Gene Expr. Patterns (IF 1.2) Pub Date : 2023-02-06 Cheng Pang, Anoop Cherian, Rushi Lan, Xiaonan Luo, Hongxun Yao
Most of the existing works on fine-grained image categorization and retrieval focus on finding similar images from the same species and often give little importance to inter-species similarities. However, these similarities may carry species correlations such as the same ancestors or similar habits, which are helpful in taxonomy and understanding biological traits. In this paper, we devise a new fine-grained
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Neurod1 mediates the reprogramming of NG2 glial into neurons in vitro Gene Expr. Patterns (IF 1.2) Pub Date : 2023-01-20 Min Wei, Zhengwei Hu, Zhenggang Lu, Zhengcun Yan, Lun Dong, Yunlong Pei, Xingdong Wang, Hengzhu Zhang
Neuronal defect and loss are the main pathological processes of many central nervous system diseases. Cellular reprogramming is a promising method to supplement lost neurons. However, study on cellular reprogramming is still limited and its mechanism remains unclear. Herein, the effect of Neurod1 expression on differentiation of NG2 glia into neurons was investigated. In this study, we successfully
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Denovo RNA-Seq analysis of ovary and testis reveals potential differentially expressed transcripts associated with gonadal unsynchronization development in Onychostoma macrolepis Gene Expr. Patterns (IF 1.2) Pub Date : 2022-12-21 Heran Cao, Long Li, Zhenpeng Li, Huihui Gao, Guofan Peng, Chao Zhu, Yining Chen, Fangxia Yang, Wuzi Dong
The Onychostoma macrolepis (O. macrolepis) is a rare and endangered wild species. Their endangered extinction might be due to their low fertility. To further illustrate the molecular mechanism of gonad development of the male and female O. macrolepis, the present study carried out de novo testicular and ovarian transcriptome sequencing. By comparing ovary and testis, 30,869 differentially expressed
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Cloning, subcellular localization and expression analysis of squalene cyclooxygenase gene BsSE1 from Bletilla striata Gene Expr. Patterns (IF 1.2) Pub Date : 2022-12-10 Shuangshuang Wang, Quanli Dou, Changling Sui, Guangyan Yuan, Boping Zeng
Squalene epoxidase catalyzes the oxidation of squalene to 2,3-oxo-squalene (BsSE1), and is the key rate limiting enzyme in the synthesis of triterpenoids and sterols in plants. This study focused on the basic aspects of BsSE1 including the sequence information, sub-cellular localization expression patterns of BsSE1. Using to the sequence information of Bletilla striata transcriptome, the full-length
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Differential gene expression associated with flower development of mango (Mangifera indica L.) varieties with different shelf-life Gene Expr. Patterns (IF 1.2) Pub Date : 2022-12-14 Nimisha Sharma, Mukesh Shivran, Narendra Singh, Anil Kumar Dubey, Sanjay Kumar Singh, Neha Sharma, Ruchi Gupta, Hatkari Vittal, Bikram Pratap Singh, Amitha Mithra Sevanthi, Nagendra Kumar Singh
Mango (Mangifera indica L.) is one of the most important commercial fruit crop grown in many parts of the world. Major challenges affecting mango trade are short shelf-life, high susceptibility to chilling injury, post-harvest diseases and consumer demand for improved fruit quality. The objective of the present study was to reveal the key regulators present in bud and flower tissues during flower development
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Comparative expression analysis of TEADs and their splice variants in mouse embryonic stem cells Gene Expr. Patterns (IF 1.2) Pub Date : 2022-12-11 Yuda Cheng, Yang Xiao, Yan Ruan, Jiali Wang, Yanping Tian, Jiaxiang Xiong, Jiaqi Wang, Fengsheng Wang, Chen Zhang, Yixiao Xu, Lianlian Liu, Meng Yu, Jiangjun Wang, Binyu Zhao, Yue Zhang, Ran Yang, Yi Yang, Zhongxiang Yao, Rui Jian, Lan Xiao, Junlei Zhang
Transcriptional enhanced associate domain (TEAD) transcription factors play important roles in embryonic stem cell (ESC) renewal and differentiation. Four TEAD transcription factors (Tead1, Tead2, Tead3 and Tead4) and their various splice variants have been discovered in mice, but the expression pattern of them during pluripotency state transition is unclear. Here, we investigated the expression of
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Fingerprint matching using the onion peeling approach and turning function Gene Expr. Patterns (IF 1.2) Pub Date : 2022-12-10 Nazanin Padkan, B. Sadeghi Bigham, Mohammad Reza Faraji
Fingerprint, as one of the most popular and robust biometric traits, can be used in automatic identification and verification systems to identify individuals. Fingerprint matching is a vital and challenging issue in fingerprint recognition systems. Most fingerprint matching algorithms are minutiae-based. The minutiae points are the ways that the fingerprint ridges can be discontinuous. Ridge ending
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Neuronal expression of ndst3 in early zebrafish development is responsive to Wnt signaling manipulation Gene Expr. Patterns (IF 1.2) Pub Date : 2022-12-09 Rebecca A. Anderson, Usua Oyarbide
Heparan sulfate proteoglycans (HSPGs) are constituents of the cell surface and extracellular matrix and are vital for various activities within the cell. The N-deacetylase/N-sulfotransferase (heparin glucosaminyl) family of enzymes, or NDST, modifies heparan sulfate (HS) by catalyzing both the N-deacetylation and the N-sulfation of N-acetylglucosamine residues. In zebrafish, a single ndst3 gene is
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Improving liver lesions classification on CT/MRI images based on Hounsfield Units attenuation and deep learning Gene Expr. Patterns (IF 1.2) Pub Date : 2022-11-28 Anh-Cang Phan, Hung-Phi Cao, Thi-Nguu-Huynh Le, Thanh-Ngoan Trieu, Thuong-Cang Phan
The early sign detection of liver lesions plays an extremely important role in preventing, diagnosing, and treating liver diseases. In fact, radiologists mainly consider Hounsfield Units to locate liver lesions. However, most studies focus on the analysis of unenhanced computed tomography images without considering an attenuation difference between Hounsfield Units before and after contrast injection
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Expression patterns and biological function of BCL2L10 during mouse preimplantation development Gene Expr. Patterns (IF 1.2) Pub Date : 2022-10-29 Yong Liu, Jing Xin, Shengnan Zhang, Qingmei Li, Wenying Wang, Ji Chen, Xin Ming, Xiaoqing Wu, Xinyan Cao, Wei Cui, Hongcheng Wang, Wenyong Li
BCL2-like 10 (BCL2L10) is abundantly expressed in mammalian oocytes and plays a crucial role in the completion of oocyte meiosis. However, the expression patterns of BCL2L10 and its biological functions during preimplantation development have not been well characterized. Here, we investigated the spatiotemporal expressions of Bcl2l10 during mouse preimplantation development using RT-qPCR and immunofluorescence
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Foxl2a and Foxl2b are involved in midbrain-hindbrain boundary development in zebrafish Gene Expr. Patterns (IF 1.2) Pub Date : 2022-10-29 Jian Zhou, Yan-Jing Yang, Rui-Hai Gan, Yang Wang, Zhi Li, Xiao-Juan Zhang, Jian-Fang Gui, Li Zhou
Foxl2 plays conserved central function in ovarian differentiation and maintenance in several fish species. However, its expression pattern and function in fish embryogenesis are still largely unknown. In this study, we first presented a sequential expression pattern of zebrafish foxl2a and foxl2b during embryo development. They were predominantly expressed in the cranial paraxial mesoderm (CPM) and
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Expression analysis of irisin during different development stages of skeletal muscle in mice Gene Expr. Patterns (IF 1.2) Pub Date : 2022-10-28 Yi Yan, Ding Yang, Pei Wen, Yilei Li, Yufang Ge, Pei Ma, Jiahui Yuan, Pengxiang Zhang, Zhiwei Zhu, Xiaomao Luo, Xiuju Yu, Haidong Wang
Background As a newly discovered muscle factor secreted by skeletal muscle cells, irisin is a polypeptide fragment formed from hydrolysis of fibronectin type Ⅲ domain-containing protein 5 (FNDC5). Irisin can promote beigeing of white adipose tissue (WAT) and regulate glucose and lipid metabolisms. However, the functions of irisin in skeletal muscle development remain largely unknown. In order to characterize
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Functional differentiation of bmp2a and bmp2b genes in zebrafish Gene Expr. Patterns (IF 1.2) Pub Date : 2022-11-02 Yaming Wu, Aili Sun, Chunhong Nie, Ze-xia Gao, Shi-Ming Wan
Bone morphogenetic protein 2 plays an important role in the regulation of osteoblast proliferation and differentiation. Phylogenetic analysis showed that the bmp2 ortholog evolved from the same ancestral gene family in vertebrates and was duplicated in teleost, which were named bmp2a and bmp2b. The results of whole-mount in situ hybridization showed that the expression locations of bmp2a and bmp2b
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Identification and expression profile of novel STAND gene Nwd2 in the mouse central nervous system Gene Expr. Patterns (IF 1.2) Pub Date : 2022-10-28 Seiya Yamada, Ryutaro Furukawa, Shin-ichi Sakakibara
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Transcriptomic mapping of the metzincin landscape in human trophoblasts Gene Expr. Patterns (IF 1.2) Pub Date : 2022-10-25 Jasmin Wächter, Matthew J. Shannon, Alexander G. Beristain
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Expression and localization of NRF2/Keap1 signalling pathway genes in mouse preimplantation embryos exposed to free fatty acids Gene Expr. Patterns (IF 1.2) Pub Date : 2022-10-13 Grace Dionne, Michele Calder, Dean H. Betts, Basim Abu Rafea, Andrew J. Watson
Obese women experience greater incidence of infertility, with reproductive tracts exposing preimplantation embryos to elevated free fatty acids (FFA) such as palmitic acid (PA) and oleic acid (OA). PA treatment impairs mouse preimplantation development in vitro, while OA co-treatment rescues blastocyst development of PA treated embryos. In the present study, we investigated the effects of PA and OA
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Stage specific gene expression of folate mediated one-carbon metabolism enzymes and transporters in buffalo oocytes and pre-implantation embryos Gene Expr. Patterns (IF 1.2) Pub Date : 2022-10-13 Shama Ansari, Sikander Saini, Shradha Jamwal, Abhishek Thakur, Amit Kumar, Priya Sehrawat, Preeti Devi, Dhruba Malakar
DNA synthesis and methylations are crucial during pre-implantation embryonic development, and are mediated by one-carbon metabolism of folates. Folates, transported into the cells via folate receptors (FOLR1 and FOLR2) and carriers (SLC19A1), are metabolized by various enzymes involved in folate-methionine cycle. However, the variations in temporal expression of folate transporters and folate-methionine
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Sexually dimorphic expression of foxl2 in the sea urchin (Mesocentrotus nudus) Gene Expr. Patterns (IF 1.2) Pub Date : 2022-10-04 Jian Zhang, Zhi-Hui Sun, Bing-Zheng Liu, Wei-Yi Su, Ya-Qing Chang
Sea urchin (Mesocentrotus nudus) is an important economically mariculture species in several Asian countries, and gonads are the sole edible parts for people. In addition to commercial value, it is an excellent model for studying gonadal development, sex determination and sex differentiation. Identify sex-related genes is an effective way to reveal the molecular mechanism of gonadal development. In
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Exponential Sailfish Optimizer-based generative adversarial network for image annotation on natural scene images Gene Expr. Patterns (IF 1.2) Pub Date : 2022-10-03 Selvin Ebenezer S, Raghuveera Tripuraribhatla
Generally, automatic image annotation can offer semantic graphics for recognizing image contents, and it creates a base for devising various techniques, which can search images in a huge dataset. Although most existing techniques mainly focus on resolving annotation issues through sculpting tag semantic information and visual image content, it ignores additional information, like picture positions
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Kurdish Handwritten character recognition using deep learning techniques Gene Expr. Patterns (IF 1.2) Pub Date : 2022-10-03 Rebin M. Ahmed, Tarik A. Rashid, Polla Fattah, Abeer Alsadoon, Nebojsa Bacanin, Seyedali Mirjalili, S. Vimal, Amit Chhabra
Handwriting recognition is regarded as a dynamic and inspiring topic in the exploration of pattern recognition and image processing. It has many applications including a blind reading aid, computerized reading, and processing for paper documents, making any handwritten document searchable and converting it into structural text form. High accuracy rates have been achieved by this technology when recognizing
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Cloning, tissue distribution of desert hedgehog (dhh) gene and expression profiling during different developmental stages of Pseudopleuronectes yokohamae Gene Expr. Patterns (IF 1.2) Pub Date : 2022-09-22 Zheng Zhang, Wenjie Wang, Yanchao Wei, Yixin Gu, Yue Wang, Xuejie Li, Wei Wang
As a crucial member of the Hedgehog (Hh) protein family, desert hedgehog (dhh) plays a vital role in multiple developmental processes, cell differentiation and tissue homeostasis. However, it is unclear how it regulates development in fish. In this study, we cloned and characterized the dhh gene from Pseudopleuronectes yokohamae. The full-length cDNA of Pydhh comprises 3194 bp, with a 1386 bp open
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Double enhanced residual network for biological image denoising Gene Expr. Patterns (IF 1.2) Pub Date : 2022-08-24 Bo Fu, Xiangyi Zhang, Liyan Wang, Yonggong Ren, Dang N.H. Thanh
With the achievements of deep learning, applications of deep convolutional neural networks for the image denoising problem have been widely studied. However, these methods are typically limited by GPU in terms of network layers and other aspects. This paper proposes a multi-level network that can efficiently utilize GPU memory, named Double Enhanced Residual Network (DERNet), for biological-image denoising
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The tissue-specificity associated region and motif of an emx2 downstream enhancer CNE2.04 in zebrafish Gene Expr. Patterns (IF 1.2) Pub Date : 2022-08-12 Xudong Chen, Qi Zhang, Jia Lin, Yinglan Zhang, Yawen Zhang, Yiting Gui, Ruizhi Zhang, Ting Liu, Qiang Li
Background Expression level of EMX2 plays an important role in the development of nervous system and cancers. CNE2.04, a conserved enhancer downstream of emx2, drives fluorescent protein expression in the similar pattern of emx2. Methods CNE2.04 truncated or motif-mutated transgenic reporter plasmids were constructed and injected into the zebrafish fertilized egg with Tol2 mRNA at the unicellular stage
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A patched1 gene homologue participates in female differentiation of Cynoglossus semilaevis Gene Expr. Patterns (IF 1.2) Pub Date : 2022-08-06 Qian Qi, Zhongdian Dong, Ning Zhang, Changwei Shao, Wenteng Xu
Patched (Ptch) is a receptor in the hedgehog signaling pathway, essential for animal development. Our previous study showed that ptch1 gene participates in the maintenance of the male germline and spermatogenesis in Cynoglossus semilaevis (csptch1). In this study, we identified a patched1 gene homolog (csptch1 x1). The csptch1 x1 gene is 5761 bp long, with a 4638 bp coding sequence that encodes 1545
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Stereo super-resolution images detection based on multi-scale feature extraction and hierarchical feature fusion Gene Expr. Patterns (IF 1.2) Pub Date : 2022-08-06 Junwei Luo, Lingyi Liu, Wenbo Xu, Qilin Yin, Cong Lin, Hongmei Liu, Wei Lu
Recently, with most mobile phones coming with dual cameras, stereo image super-resolution is becoming increasingly popular in phones and other modern acquisition devices, leading stereo super-resolution images spread widely on the Internet. However, current image forensics methods are carried out in monocular images, and high false positive rate appears when detecting stereo super-resolution images
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Optimization assisted framework for thyroid detection and classification: A new ensemble technique Gene Expr. Patterns (IF 1.2) Pub Date : 2022-08-05 Rajole Bhausaheb Namdeo, Gond Vitthal Janardan
Ultrasound (US) is an inexpensive and non-invasive technique for capturing the image of the thyroid gland and nearby tissue. The classification and detection of thyroid disorders is still in its infant stage. This study aims to present a new thyroid diagnosis approach, which consists of three phases like “(i) feature extraction, (ii) feature dimensionality reduction, and (iii) classification”. Initially
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Robust secret image sharing scheme resistance to maliciously tampered shadows by AMBTC and quantization Gene Expr. Patterns (IF 1.2) Pub Date : 2022-08-05 Yuyuan Sun, Ching-Nung Yang, Xuehu Yan, Yuliang Lu, Lei Sun
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V - Channel magnification enabled by hybrid optimization algorithm: Enhancement of video super resolution Gene Expr. Patterns (IF 1.2) Pub Date : 2022-07-20 Rohita H. Jagdale, Sanjeevani K. Shah
Although being a really active area of research, television super-resolution remains a difficult problem. Additionally, it is noted that the blur motion and computational crisis hinder the enhancement. As a result, the goal of this research is to present a brand-new smart SR framework for the camera shot. To create High Resolution (HR) videos, first frames in RGB format are converted to HSV and then
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Leveraging ShuffleNet transfer learning to enhance handwritten character recognition Gene Expr. Patterns (IF 1.2) Pub Date : 2022-07-16 Qasem Abu Al-Haija
Handwritten character recognition has continually been a fascinating field of study in pattern recognition due to its numerous real-life applications, such as the reading tools for blind people and the reading tools for handwritten bank cheques. Therefore, the proper and accurate conversion of handwriting into organized digital files that can be easily recognized and processed by computer algorithms
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inka1b expression in the head mesoderm is dispensable for facial cartilage development Gene Expr. Patterns (IF 1.2) Pub Date : 2022-07-08 Haewon Jeon, Sil Jin, Chong Pyo Choe
Inka box actin regulator 1 (Inka1) is a novel protein identified in Xenopus and is found in vertebrates. While Inka1 is required for facial skeletal development in Xenopus and zebrafish, it is dispensable in mice despite its conserved expression in the cranial neural crest, indicating that Inka1 function in facial skeletal development is not conserved among vertebrates. Zebrafish bears two paralogs
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Visual and buying sequence features-based product image recommendation using optimization based deep residual network Gene Expr. Patterns (IF 1.2) Pub Date : 2022-07-08 D.N.V.S.L.S. Indira, Babu Rao Markapudi, Kavitha Chaduvula, Rathna Jyothi Chaduvula
A recommendation system is an imaginative resolution for managing the restrictions in e-commerce services with item details and user details. Also, it is used to determine the user preferences to recommend the items they expected to buy. Several conventional collaborative filtering techniques are devised in the recommender model, but it has some complexities. Hence, an innovative optimization-driven
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Transcriptome analysis of walnut quality formation and color change mechanism of pellicle during walnut development Gene Expr. Patterns (IF 1.2) Pub Date : 2022-06-26 Yajun Zeng, Hengzhao Liu, Shenqun Chen, Gang Wang, Jun Chen, Zhongke Lu, Na Hou, Guijie Ding, Peng Zhao
Walnuts (including those covered with a pellicle) are loved for their rich nutritional value. And the popular varieties of walnut cultivation are Juglans sigillata L. The pellicle (seed coat) of these walnut cultivars has different colors and has an indispensable influence on the walnut quality formation. However, there are few reports on the pellicle color and quality formation in different developmental
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AMB-Wnet: Embedding attention model in multi-bridge Wnet for exploring the mechanics of disease Gene Expr. Patterns (IF 1.2) Pub Date : 2022-06-16 Chunxing Wang, Xiaodong Jiang, Zixuan Wang, Xiaorui Guo, Wenbo Wan, Jian Wang
In recent years, progressive application of convolutional neural networks in image processing has successfully filtered into medical diagnosis. As a prerequisite for images detection and classification, object segmentation in medical images has attracted a great deal of attention. This study is based on the fact that most of the analysis of pathological diagnoses requires nuclei detection as the starting