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The effect of canagliflozin on gut microbiota and metabolites in type 2 diabetic mice Genes Genom. (IF 2.1) Pub Date : 2024-03-14
Abstract Background Sodium glucose cotransporter 2 inhibitor (SGLT2i) represent a new type of hypoglycemic medicine that can cause massive loss of glucose from the urine, which have several benefits of reducing body weight and improving the prognosis of cardiovascular and kidney diseases. Although they are oral medicated hypoglycemic agents, their effects on the gut microbiome and function have been
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Whole genome sequencing of mouse lines divergently selected for fatness (FLI) and leanness (FHI) revealed several genetic variants as candidates for novel obesity genes Genes Genom. (IF 2.1) Pub Date : 2024-03-14 Martin Šimon, Špela Mikec, Santosh S. Atanur, Janez Konc, Nicholas M. Morton, Simon Horvat, Tanja Kunej
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Deubiquitinase BRCC3 promotes the migration, invasion and EMT progression of colon adenocarcinoma by stabilizing MET expression Genes Genom. (IF 2.1) Pub Date : 2024-03-12 Xiu Feng, Shengnan He, Ying Chen, Liang Zhang
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DJ-1 protects cell death from a mitochondrial oxidative stress due to GBA1 deficiency Genes Genom. (IF 2.1) Pub Date : 2024-03-09 Younwoo Nam, Jiyeon Na, Shi-Xun Ma, Haeun Park, Hyeonwoo Park, Eunmin Lee, Hyerynn Kim, Sang-Min Jang, Han Seok Ko, Sangjune Kim
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Correlation analysis of cancer stem cell marker CD133 and human endogenous retrovirus (HERV)-K env in SKOV3 ovarian cancer cells Genes Genom. (IF 2.1) Pub Date : 2024-03-08 Do-Ye Kim, Heungyeol Kim, Eun-Ji Ko, Suk Bong Koh, Hongbae Kim, Ji Young Lee, Chul Min Lee, Wan Kyu Eo, Ki Hyung Kim, Hee-Jae Cha
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Comparative whole genome analysis of face-derived Streptococcus infantis CX-4 unravels the functions related to skin barrier Genes Genom. (IF 2.1) Pub Date : 2024-03-07 Haeun Lee, Dong-Geol Lee, HyungWoo Jo, Young Mok Heo, Chaeyun Baek, Hye-been Kim, Geunhwa Park, Seunghyun Kang, Wooseok Lee, Seyoung Mun, Kyudong Han
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Bioinformatics analysis and experimental validation reveal that CDC20 overexpression promotes bladder cancer progression and potential underlying mechanisms Genes Genom. (IF 2.1) Pub Date : 2024-03-04 Yuan Liu, Shao-hui Zou, Xin Gao
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T-DNA insertion mutants of Arabidopsis DA1 orthologous genes displayed altered plant height and yield-related traits in rice (O. Sativa L.) Genes Genom. (IF 2.1) Pub Date : 2024-03-04 Kyu-Chan Shim, Ngoc Ha Luong, Thomas H. Tai, Gyu-Ri Lee, Sang-Nag Ahn, Inkyu Park
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Transcriptome profiling and characterization of genes associated with tuberization under high temperature in aeroponics in potato cv. Kufri Anand Genes Genom. (IF 2.1) Pub Date : 2024-02-21
Abstract Background High temperature stress is an important abiotic factor, which affects tuberization and ultimately causes heavy yield reduction in potato. Objectives Identification and characterization of genes associated with tuberization under high temperature stress is essential for future management through biotechnology. Methodology Two contrasting potato varieties Kufri Anand (profuse tuber-bearing)
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Population genetics reveals new introgression in the nucleus herd of min pigs Genes Genom. (IF 2.1) Pub Date : 2024-02-21
Abstract Objective Min pigs are a unique genetic resource among local pig breeds in China. They have more excellent characteristics in cold and stress resistance, good meat quality, and a high reproductive rate. However, the genetic structure and driving factors remain unclear in the nucleus herd. In this study, the genetic diversity of Min pigs was studied to reveal the formation mechanism of its
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A rare TNNT1 gene variant causing creatine kinase elevation in nemaline myopathy: c.271_273del (p.Lys91del) Genes Genom. (IF 2.1) Pub Date : 2024-02-16 Cüneyd Yavaş, Mustafa Doğan, Recep Eröz, Kübra Türegün
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Molecular characterization and expression pattern of Rubisco activase gene GhRCAβ2 in upland cotton (Gossypium hirsutum L.) Genes Genom. (IF 2.1) Pub Date : 2024-02-07 Maoni Chao, Ling Huang, Jie Dong, Yu Chen, Genhai Hu, Qiufang Zhang, Jinbao Zhang, Qinglian Wang
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Expression of ethylene biosynthetic genes during flower senescence and in response to ethephon and silver nitrate treatments in Osmanthus fragrans Genes Genom. (IF 2.1) Pub Date : 2024-02-06 Hui Qiu, Yiwen Chen, Jianxin Fu, Chao Zhang
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Genetic specificity study using next-generation sequencing (NGS) of peritoneal metastatic colorectal cancer compared to primary colorectal cancer Genes Genom. (IF 2.1) Pub Date : 2024-02-05 Sungchul Lee, Wonseok Shin, Dong-Guk Park, Hwan Namgung
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Profiling of testis-specific or testis-predominant genes expressed in mouse male germ cell lines GC-1 and GC-2 Genes Genom. (IF 2.1) Pub Date : 2024-01-30
Abstract Background Spermatogenesis is a tightly organized process that utilizes an intrinsic genetic program composed of germ cell-specific genes. Although mouse germ cell-related cell lines are available, few germ cell-specific genes have been comprehensively identified in such cell lines. Objective We aimed to profile gene expression in the male mouse germ cell-related cell lines, GC-1 and GC-2
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Correction: Suppression of synuclein gamma inhibits the movability of endometrial carcinoma cells by PI3K/AKT/ERK signaling pathway Genes Genom. (IF 2.1) Pub Date : 2024-01-24 Man Ni, Yue Zhao, Xiaoguang Wang
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Childhood-related neural genotype–phenotype in ATP1A3 mutations: comprehensive analysis Genes Genom. (IF 2.1) Pub Date : 2024-01-19 Osama Y. Muthaffar, Asma Alqarni, Jumana A. Shafei, Sarah Y. Bahowarth, Anas S. Alyazidi, Muhammad Imran Naseer
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PSMD12 promotes non-small cell lung cancer progression through activating the Nrf2/TrxR1 pathway Genes Genom. (IF 2.1) Pub Date : 2024-01-19 Junqi Lv, Shengmao Ma, Xiaowen Wang, Jifang Dang, Fuchun Ma
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Genome assembly and microsatellite marker development using Illumina and PacBio sequencing in Persicaria maackiana (Polygonaceae) from Korea Genes Genom. (IF 2.1) Pub Date : 2024-01-19 Kang-Rae Kim, So Young Park, Heesoo Kim, Jiyeon Kim, Jeong Min Hong, Sun-Yu Kim, Jeong-Nam Yu
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Role of Brassica rapa SWEET genes in the defense response to Plasmodiophora brassicae Genes Genom. (IF 2.1) Pub Date : 2024-01-18 Jae-Han Choi, Eun Cho, Ji-Woo Kim, Soo Min Lee, Gyung Ja Choi, Su Ryan Choi, Man Sung Yang, Yong Pyo Lim, Man-Ho Oh
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Human umbilical cord mesenchymal stem cells overexpressing RUNX1 promote tendon-bone healing by inhibiting osteolysis, enhancing osteogenesis and promoting angiogenesis Genes Genom. (IF 2.1) Pub Date : 2024-01-05 Dan Guo, Jian Yang, Dianwei Liu, Pei Zhang, Hao Sun, Jingcheng Wang
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A novel approach of kinship determination based on the physical length of genetically shared regions of chromosomes Genes Genom. (IF 2.1) Pub Date : 2024-01-05 Sohee Cho, Eunsoon Shin, Yoon Gi Park, Seung Ho Choi, Eun Kyung Choe, Jung Ho Bae, Jong-Eun Lee, Soong Deok Lee
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Construction of methylation driver gene-related prognostic signature and development of a new prognostic stratification strategy in neuroblastoma Genes Genom. (IF 2.1) Pub Date : 2024-01-05 Yahui Han, Biyun Li, Jian Cheng, Diming Zhou, Xiafei Yuan, Wei Zhao, Da Zhang, Jiao Zhang
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PIM3 regulates myocardial ischemia/reperfusion injury via ferroptosis Genes Genom. (IF 2.1) Pub Date : 2023-12-26 Ting Li, Fangyao Liu, Ying Tan, Yutao Peng, Xuefeng Xu, Yushan Yang
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Clinical report and genetic analysis of a novel variant in ZMIZ1 causing neurodevelopmental disorder with dysmorphic factors and distal skeletal anomalies in a Chinese family Genes Genom. (IF 2.1) Pub Date : 2023-12-20 Liting He, Yao Wang, Jiahua Pan, Limin Guo, Haoquan Zhou, Lan Zhang
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O- and N-Methyltransferases in benzylisoquinoline alkaloid producing plants Genes Genom. (IF 2.1) Pub Date : 2023-12-14 Seungki Lee, Nam-Il Park, Yeri Park, Kyong-Cheul Park, Eun Sil Kim, Youn Kyoung Son, Beom-Soon Choi, Nam-Soo Kim, Ik-Young Choi
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Downregulated CDH3 is correlated with a better prognosis for LUAD and decreases proliferation and migration of lung cancer cells Genes Genom. (IF 2.1) Pub Date : 2023-12-08 Wanru Ma, Junhua Hu
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A review on gene regulatory network reconstruction algorithms based on single cell RNA sequencing Genes Genom. (IF 2.1) Pub Date : 2023-11-30 Hyeonkyu Kim, Hwisoo Choi, Daewon Lee, Junil Kim
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Integration of single-cell transcriptomics and epigenetic analysis reveals enhancer-controlled TIMP1 as a regulator of ferroptosis in colorectal cancer Genes Genom. (IF 2.1) Pub Date : 2023-11-30 Meng Li, Qian-yang Ni, Su-yang Yu
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Feature selection for effective prediction of SARS-COV-2 using machine learning Genes Genom. (IF 2.1) Pub Date : 2023-11-20 Gagan Punacha, Rama Adiga
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Characterization and comparative analysis of the complete organelle genomes of three red macroalgae species (Neoporphyra dentata, Neoporphyra seriata, and Neopyropia yezoensis) and development of molecular makers for their identification Genes Genom. (IF 2.1) Pub Date : 2023-11-23 Yong Jin Lee, Yo Ram Uh, Yeon Mi Kim, Cheol Min Kim, Cheol Seong Jang
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Comparative transcriptome analysis of two contrasting genotypes provides new insights into the drought response mechanism in pigeon pea (Cajanus cajan L. Millsp.) Genes Genom. (IF 2.1) Pub Date : 2023-11-20 Suman Pahal, Harsha Srivastava, Swati Saxena, Kishor U. Tribhuvan, Tanvi Kaila, Sandhya Sharma, Sapna Grewal, Nagendra K. Singh, Kishor Gaikwad
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Disclosing the hidden nucleotide sequences: a journey into DNA barcoding of raptor species in public repositories Genes Genom. (IF 2.1) Pub Date : 2023-11-20 Wattanawan Jaito, Jumaporn Sonongbua, Thitipong Panthum, Pish Wattanadilokcahtkun, Nattakan Ariyaraphong, Thanyapat Thong, Worapong Singchat, Syed Farhan Ahmad, Ekaphan Kraichak, Narongrit Muangmai, Kyudong Han, Agostinho Antunes, Ratiwan Sitdhibutr, Akihiko Koga, Prateep Duengkae, Chaiyan Kasorndorkbua, Kornsorn Srikulnath
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Genetic insights: mapping sex-specific loci in Siamese cobra (Naja kaouthia) sheds light on the putative sex determining region Genes Genom. (IF 2.1) Pub Date : 2023-11-20 Wattanawan Jaito, Thitipong Panthum, Syed Farhan Ahmad, Worapong Singchat, Narongrit Muangmai, Kyudong Han, Akihiko Koga, Prateep Duengkae, Kornsorn Srikulnath
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SRSF7 is a promising prognostic biomarker in hepatocellular carcinoma and is associated with immune infiltration Genes Genom. (IF 2.1) Pub Date : 2023-11-20 Wei Shen, Lebin Yuan, Fei Cheng, Zhao Wu, Xiaodong Li
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DNA methylation of GDF-9 and GHR genes as epigenetic regulator of milk production in Egyptian Zaraibi goat Genes Genom. (IF 2.1) Pub Date : 2023-11-20 Layaly Gamal, Magda M. Noshy, A. M. Aboul-Naga, Hussein Sabit, Haidan M. El-Shorbagy
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Single-cell transcriptomic analysis reveals transcriptional and cell subpopulation differences between human and pig immune cells Genes Genom. (IF 2.1) Pub Date : 2023-11-18 Jie Li, Yanan Xu, Jiayu Zhang, Zhaoqi Zhang, Han Guo, Dong Wei, Changhong Wu, Tang Hai, Hai-Xi Sun, Yong Zhao
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Mycobacterium tuberculosis virulence protein ESAT-6 influences M1/M2 polarization and macrophage apoptosis to regulate tuberculosis progression Genes Genom. (IF 2.1) Pub Date : 2023-11-16 Feng Sun, Jiangbo Li, Ling Cao, Cunzi Yan
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Skin benefits of postbiotics derived from Micrococcus luteus derived from human skin: an untapped potential for dermatological health Genes Genom. (IF 2.1) Pub Date : 2023-11-16 Young Mok Heo, Dong-Geol Lee, Seyoung Mun, Minji Kim, Chaeyun Baek, Haeun Lee, Seok Kyun Yun, Seunghyun Kang, Kyudong Han
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SUZ12 inhibition attenuates cell proliferation of glioblastoma via post-translational regulation of CDKN1B Genes Genom. (IF 2.1) Pub Date : 2023-10-19 Sojin Kim, Sungsin Jo, Sun Ha Paek, Sang Soo Kang, Heekyoung Chung
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ACT001 alleviates inflammation and pyroptosis through the PPAR-γ/NF-κB signaling pathway in LPS-induced alveolar macrophages Genes Genom. (IF 2.1) Pub Date : 2023-10-13 Qiang Fu, Na Shen, Tao Fang, Hewei Zhang, Yanbo Di, Xuan Liu, Chao Du, Jianshuang Guo
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Cell death induction and intracellular vesicle formation in human colorectal cancer cells treated with Δ9-Tetrahydrocannabinol Genes Genom. (IF 2.1) Pub Date : 2023-10-14 Yu-Na Hwang, In-Seo Kwon, Ju-Hee Park, Han-Heom Na, Tae-Hyung Kwon, Jin-Sung Park, Keun-Cheol Kim
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StringFix: an annotation-guided transcriptome assembler improves the recovery of amino acid sequences from RNA-Seq reads Genes Genom. (IF 2.1) Pub Date : 2023-10-14 Joongho Lee, Minsoo Kim, Kyudong Han, Seokhyun Yoon
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Naringenin ameliorates atopic dermatitis by inhibiting inflammation and enhancing immunity through the JAK2/STAT3 pathway Genes Genom. (IF 2.1) Pub Date : 2023-10-14 Limin Tian, Mengjie Wang, Yangxingyun Wang, Wei Li, Yuenan Yang
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ANXA3, associated with YAP1 regulation, participates in the proliferation and chemoresistance of cervical cancer cells Genes Genom. (IF 2.1) Pub Date : 2023-10-16 Jiazhen Huang, Wei Wei, Fuli Kang, Shuang Tan, Yibing Li, Xiaohang Lu, Ning Wang
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Identification of genomic-wide genetic links between cutaneous melanoma and obesity-related physical traits via cFDR Genes Genom. (IF 2.1) Pub Date : 2023-09-28 Shen Lin, Runnan Shen, Jingqian Huang, Yanhan Liu, Hongpeng Li, Qingfang Xu
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Characteristics of insulin resistance in Korean adults from the perspective of circadian and metabolic sensing genes Genes Genom. (IF 2.1) Pub Date : 2023-09-28 Miso S. Park, Siwoo Lee, Younghwa Baek, Juho Lee, Sang-Soo Park, Jung-Hyo Cho, Hee-Jeong Jin, Ho-Ryong Yoo
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VDR promotes testosterone synthesis in mouse Leydig cells via regulation of cholesterol side chain cleavage cytochrome P450 (Cyp11a1) expression Genes Genom. (IF 2.1) Pub Date : 2023-09-25 Yuanyuan Hu, Ling Wang, Ge Yang, Shanshan Wang, Miaomiao Guo, Hongzhao Lu, Tao Zhang
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Puerarin alleviates chronic renal failure-induced pyroptosis in renal tubular epithelial cells by targeting miR-342-3p/TGF-β/SMAD axis Genes Genom. (IF 2.1) Pub Date : 2023-09-25 Jing Yang, Baochao Li, Jiangming Wang, Wenxing Fan
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LncRNA KTN1-AS1 facilitates esophageal squamous cell carcinoma progression via miR-885-5p/STRN3 axis Genes Genom. (IF 2.1) Pub Date : 2023-09-25 Liying Chen, Juntao Lu, Xiaoxu Li, Xinhao Wang, Ruoyang Qiao, Wei Guo, Qian Ren
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ST6GALNAC1 promotes the invasion and migration of breast cancer cells via the EMT pathway Genes Genom. (IF 2.1) Pub Date : 2023-09-25 Yunzhao Luo, Heng Cao, Chuqi Lei, Jun Liu
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Suppression of TBCK enhances TRAIL-mediated apoptosis by causing the inactivation of the akt signaling pathway in human renal carcinoma Caki-1 cells Genes Genom. (IF 2.1) Pub Date : 2023-09-19 Cho-Young Park, Ji-Hoon Jang, In-Hwan Song, Joo-Young Kim, Kyung-Oh Doh, Tae-Jin Lee
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LncRNA LINC01123 promotes malignancy of ovarian cancer by targeting hsa-miR-516b-5p/VEGFA Genes Genom. (IF 2.1) Pub Date : 2023-09-20 Bing Dong, Cuiping Li, Xiaomeng Xu, Yan Wang, Yuewen Li, Xingmei Li
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HPF1 regulates tendon stem/progenitor cell senescence and tendon repair via PARP1-mediated poly-ADP ribosylation of HuR Genes Genom. (IF 2.1) Pub Date : 2023-09-15 Weifeng Han, Dongqiang GU, Hongguang Chen, Xu Tao, Lei Chen
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Repurposing existing drugs for monkeypox: applications of virtual screening methods Genes Genom. (IF 2.1) Pub Date : 2023-09-15 Vladimir Li, Youngho Lee, Chul Lee, Heebal Kim
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m6A-mediated lncRNA NEAT1 plays an oncogenic role in non-small cell lung cancer by upregulating the HMGA1 expression through binding miR-361-3p Genes Genom. (IF 2.1) Pub Date : 2023-09-09 Li Qi, Yue Yin, Mengqi Sun
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Comprehensive analysis of circular RNAs in nasopharyngeal cancer Genes Genom. (IF 2.1) Pub Date : 2023-08-31 Si-Yu Zhu, Xiao-Yi Wang, Hui Xie, Li-Zhi Liu
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A comparative investigation of single nucleotide variant calling for a personal non-Caucasian sequencing sample Genes Genom. (IF 2.1) Pub Date : 2023-08-31 HyeonSeul Park, JungSoo Gim
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Mechanism of E2F1 in the proliferation, migration, and invasion of endometrial carcinoma cells via the regulation of BMI1 transcription Genes Genom. (IF 2.1) Pub Date : 2023-08-30 Yanyang Lu, Ying Wei, Xiaoqin Shen, Yixi Tong, Jin Lu, Yahui Zhang, Yun Ma, Rong Zhang
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Interference KRT17 reverses doxorubicin resistance in triple-negative breast cancer cells by Wnt/β-catenin signaling pathway Genes Genom. (IF 2.1) Pub Date : 2023-08-27 Liqiong Wu, Wenshuang Ding, Xiaopai Wang, Xiubo Li, Jing Yang