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Apelin is Peptide Increasing Tolerance of Organs and Cells to Hypoxia and Reoxygenation. The Signaling Mechanism Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2024-03-14 Sergey Valentinovich Popov, Leonid Nikolaevich Maslov, Alexandr Valerievich Mukhomedzyanov, Maria Sirotina, Natalia Vladimirovna Naryzhnaya, Boris Konstantinovich Kurbatov, Alexandr Sergeevich Gorbunov, Michail Kilin, Viacheslav Nikolaevich Azev, Nirmal Singh, Feng Fu, Jian-Ming Pei
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Evaluation of the Anti-biofilm Efficacy of Kyotorphin Derivatives and Biosafety Assessment: In Vitro and In Vivo Investigations Targeting Bacterial and Fungal Pathogens Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2024-03-11 Isabel Chaves Silva Carvalho, Fernanda da Silva Seiffert Simões, Vitor Martins de Andrade, Dayane Batista Tada, Montserrat Heras, Eduard Bardají, Mônica Lopes Ferreira, Miguel Augusto Rico Botas Castanho, Katia Conceição
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Peptide Derivatives of Human and Rabbit Cathelicidin Reduce Inflammatory Cytokines in Peripheral Blood Mononuclear Cells of Rheumatoid Arthritis Patients Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2024-03-05 Marzieh Bashi, Rasoul Baharlou, Dariush Haghmorad, Raziyeh Lashkari, Bahman Yousefi, Hamid Madanchi
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Investigating the Effects of Melittin-Loaded Pectin as Novel Anti Breast Cancer Drug to Increase the Apoptosis Rate Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2024-02-28 Esmaeil Alibeigi, Arsham Azari Dehkordi, Milad Asadian, Abbas Doosti, Tohid Piri-Gharaghie
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Evaluation of Anti-endotoxin Activity, Hemolytic Activity, and Cytotoxicity of a Novel Designed Peptide: An In Silico and In Vitro Study Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2024-02-28 Sadra Samavarchi Tehrani, Hamideh Mahmoodzadeh Hosseini, Seyed Ali Mirhosseini
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Therapeutic Peptides and Proteins: Stabilization Challenges and Biomedical Applications by Means of Nanodelivery Systems Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2024-02-28 Elisa Berselli, Carlotta Coccolini, Giovanni Tosi, Evren H. Gökçe, M. Beatriz P. P. Oliveira, Faezeh Fathi, Karolline Krambeck, Eliana B. Souto
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Purification and Characterization of a Novel Anticoagulant Peptide from Protein Hydrolysate of Eupolyphaga sinensis Walker Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2024-02-26 Xidong Li, Xuefei Zhuang, Huifen Li, Linmei Pan, Rui Liu, Huaxu Zhu, Zhishu Tang
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Current Status of Therapeutic Peptides for the Management of Diabetes Mellitus Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2024-02-20 Arvee Prajapati, Dhwani Rana, Shagun Rangra, Anil B. Jindal, Derajram Benival
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Diving into the Venom Apparatus Transcriptomes of Pterois antennata and Pterois radiata: Unearthing a Novel Genus-Specific Piscidin-3 Homolog and a Multifarious Repertoire of Antimicrobial Peptides Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2024-02-07 Parthkumar Prajapati, Riya Desai, Mamta Varma, Ketankumar Panchal, Subhash Jakhesara, Prakash Koringa, Vaibhav Bhatt, Neelam Nathani, Chandrashekar Mootapally
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Characterization of Novel Antimicrobial Peptides from the Epidermis of Clarias batrachus Catfish Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2024-02-03
Abstract In this study, an antimicrobial protein (AMP) from the epidermis of catfish (Clarias batrachus) was purified and characterized for its molecular and antimicrobial properties. The crude epidermal extract was subjected to precipitation of proteins using 70% ammonium sulphate saturation followed by dialysis and protein separation by reverse phase ultra fast liquid chromotography (UFLC) using
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Investigating the Characteristics of Nanoliposomes Carrying Bioactive Peptides Obtained from Shrimp Waste Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2024-01-24
Abstract The aim of the paper was to develop chitosan-coated nanoliposomes for carrying bioactive peptides derived from hydrolyzed shrimp waste (SW) with chitosan coating (concentrations of 0, 0.5 and 1% W/ V). The study involved producing SW hydrolysates using protease enzymes from Bacillus salsus bacteria, followed by investigating the physicochemical, antioxidant, and antimicrobial properties of
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Lipopeptide Biosurfactant Produced by Acinetobacter junii B6 Attenuates Lung Inflammatory, Oxidative, and Histopathological Alterations due to Asthma in Rats Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2024-01-08 Mohammad Abbas Bejeshk, Mohammad Amin Rajizadeh, Abolfazl Yari, Fatemeh Bagheri, Hamid Najafipour, Gholamreza Dehghannoudeh, Niyan Salehi, Mehrnaz Mehrabani, Mandana Ohadi, Amir Hashem Aminizadeh
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Systematic Profiling of Mitogen-Inducible Gene 6 and Its Derived Peptides Binding to Receptor Tyrosine Kinases in Bone Cancers at Molecular and Cellular Levels Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2024-01-04 Jinping Ni, Zhidong Zhong, Weikang Lu, Shuai Li, Xiang Shao, Lihua Hang
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Design and Production of a Chimeric Enzyme with Efficient Antibacterial Properties on Staphylococcus aureus Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2024-01-02 Amin M. Saber, Hossein Aghamollaei, Hadi Esmaeili Gouvarchin Ghaleh, Mozafar Mohammadi, Said Yaghoob Sehri, Gholamreza Farnoosh
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The Types and Applications of Peptibodies Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-12-27 Mohammadmahdi Nemati, Ahmadreza Ahmadi, Ahmad Hashemzehi, Farukhruzi Nasrullozoda, Mohsen Abedi, Masoud Hashemzaei
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Scaled-up Synthesis and Characterization of Oxytocin Trisulfide Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-12-26 Robert P. Hammer, Melissa A. Butrie, Karen Davidson, Phillip T. Goldblatt, Alex M. Schrader, Joseph J. Dalluge, Allyn Becker, George Barany
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Evaluation of the Antimicrobial Efficacy of Epidermal Mucus Extract from Air-Breathing Fish (Channa punctatus) and Identification of the Peptides Serving as Immune Components Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-12-18 Ahmed Hussain, Shashwati Ghosh Sachan
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Design and Self Assembly of Tri-Terpene Peptide Conjugates and Their Interactions with EGFR and EGFR Mutant Receptors: An In Silico and In Vitro Study Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-12-14 Mia I. Rico, Beatriz G. Goncalves, Hannah L. Hunt, Ipsita A. Banerjee
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A Review of the in Silico Design and Development Approaches of Ras-Specific Anticancer Therapeutics Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-12-02 Parinaz Motiei, Hamid Reza Heidari, Mohammad Saeid Hejazi, Ommoleila Molavi, Elnaz Mehdizadeh Aghdam
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Cytotoxic Activity of A New Isoform l-Amino Acid Oxidase (Balt-LAAO-II) From Bothrops alternatus (Urutu) Snake Venom in Human Leukemic HL60 Cells Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-11-22 Mauricio Aurelio Gomes Heleno, Alexandre Nowill, João Ernesto de Carvalho, Diego L. Suni-Curasi, Julissa Vilca-Quispe, Emilio Alberto Ponce-Fuentes, Gustavo Alberto Obando-Pereda, Luis Alberto Ponce-Soto
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Peptidomic Analysis and Potential Bioactive Peptides Identification Targeting Endometrial Cancer Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-11-13 Hanzi Xu, Shenglong Yuan, Lin Zhou, Huixin Li, Juan Lv, Xiaoyan Shi, Wangfei Wu, Zhijian Feng, Zhen Gong
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Investigating the Effects of Temporin-Rb, an Antimicrobial Peptide, on Cell Viability and Pro-inflammatory Gene Expression in A549 Cells Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-11-09 Niloufar Shakibapour, Ahmad Asoodeh, Yasamin Yousefi, Jamshidkhan Chamani
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Antibacterial Mechanism of a Novel Peptide Dendrocin‑ZM1 Against Staphylococcus aureus by Increasing Membrane Permeability Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-11-08 Sima Sadat Seyedjavadi, Mehdi Razzaghi-Abyaneh, Parmida Bagheri, Mehdi Goudarzi
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Improving the Antibacterial Activity of Tryptophan-Containing Peptide Nanostructures Through Self-Assembly Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-11-06 Lei Zhao, Zhaoyang Liu, Mingyang Ji
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BMAP-27 Peptide Reduces Proliferation and Increases Apoptosis in Primary and Metastatic Colon Cancer Cell Lines Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-10-19 Alakesh Das, Dikshita Deka, Nabajyoti Baildya, Antara Banerjee, Atil Bisgin, Suman Adhikari, Asim K. Duttaroy, Surajit Pathak
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Anti-Inflammatory Mechanism of Walnut Meal Peptide/ Ellagic Acid Nanoparticles on LPS-Stimulated RAW264.7 Cells by Inhibition of NF-κB and MAPK Activation Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-10-16 Yuxi Ling, Yanxia Feng, Ziqi Li, Le Cheng, Xuan Zhang, Difeng Ren
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Dried Blood Spot Sampling in Protein and Peptide Bioanalysis: Optimism, Experience, and the Path Forward Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-10-04 Sneha Kaareddy, Pooja Dhakne, Megha Pillai, Niraj Rajput, Tarang Jadav, Rakesh K. Tekade, Pinaki Sengupta
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In Vitro Biological Evaluation and Mechanism of Action of Peptoid Analogue Based on Cationic, Amphipathic Peptide A-12 Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-10-04 Lalita Sharma, Gopal Singh Bisht
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Aspartame, a Synthetic Dipeptide Mediated Biochemical and Histopathological Alterations in Hepato-nephric Tissues of Mice and Pharmaceutical Intervention by Sesame Oil Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-10-03 Chaman Ara, Memoona Arshad, Shaukat Ali, Hafiz Abdullah Shakir, Muhammad Summer, Muhammad Khan, Iram Liaqat, Madeeha Arshad
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Evaluation of Antimicrobial Property of Bacteriocin Capped Silver Nanoparticles Prepared from Cell Free Supernatant of Lactobacillus brevis Isolated from Marine Fishes Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-09-28 Tamil Selvi Alagumuthu, Sugapriya Samidurai, Yasmin Khambhaty, Kanagaraj James
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Protein Hydrogels: A Concise Review of Properties and Applications Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-09-25 Bhawna Malik, Rekha Chawla, Sunil Kumar Khatkar
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Recent Advancements in Novel Bioactive Peptides and Protein Hydrolysates Isolated from Different Medicinal Plants Along with Their Applications in Food and Pharmaceutical Industries Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-09-25 Vaishali Sharma, Prerna Gupta, Poorva Sharma
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Analysis of the Glycoprotein Properties and Glycan Structures of Chicken Angiotensin Converting Enzyme 2 Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-09-22 Xiaoxia Ji, Chang Ma, Yafeng Zhang, Xinyu Du, Yuanshu Zhang
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Antibiotic-Peptide Conjugation Against Multi-drug Resistant Pathogens: A Comprehensive Review for Therapeutics and Drug Delivery Strategies Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-09-04 Karuppanan Kalimuthu, N. R. Srinivasan, G. Govindarajan
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The Therapeutic Anticancer Potential of Marine-Derived Bioactive Peptides: A Highlight on Pardaxin Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-08-31 Yong Hui Wong, Sharon Rachel Wong, Sau Har Lee
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Molecular Modelling, Synthesis, and In-Vitro Assay to Identify Potential Antiviral Peptides Targeting the 3-Chymotrypsin-Like Protease of SARS-CoV-2 Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-08-30 Ryan Faddis, Sydney Du, James Stewart, Mohammad Mehedi Hasan, Noam Lewit, Md Ackas Ali, Cladie B. White, Patience Okoto, Sures Thallapuranam, Mohammad A. Halim
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Genetically Fused DARPins: A Novel Approach for Designing Extended-Release Thrombopoietin Mimetic Peptides Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-08-21 Zhilong Shi, Fupeng Ren, Xiu Shen, Chaoying Zhang, Yingming Jin, Yiquan Cheng
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A Review on Mitochondrial Derived Peptide Humanin and Small Humanin-Like Peptides and Their Therapeutic Strategies Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-08-17 H. Thamarai Kannan, Praveen Kumar Issac, Nibedita Dey, Ajay Guru, Jesu Arockiaraj
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Antibacterial Potential of a De-Novo Designed Peptide Against Bacterial Fish Pathogens Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-08-04 Raja Aadil Hussain Bhat, Victoria C. Khangembam, Vinita Pant, Ritesh Shantilal Tandel, Pramod Kumar Pandey, Dimpal Thakuria
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Heterologous Expression and Initial In Silico Characterization of a Novel Snakin-Z Peptide Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-08-01 Tuğba Teker, Gülruh Albayrak, Kadir Turan
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Peptides from Animal Venom and Poisons Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-07-28 Ana Novo de Oliveira, Andreimar Martins Soares, Saulo Luís da Silva
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Free Radical Scavenging-Related Antioxidant Properties and Inhibitory Activities of Telfairia occidentalis Seed Protein Hydrolysates and Peptide Fractions Against Two key Enzymes Implicated in Diabetes Mellitus Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-07-28 Olasehinde Oluwaseun Ruth, Adeoye Raphael Idowu, Afolabi Olakunle Bamikole, Arise Rotimi Olusanya
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A Cross-Sectional Analysis of Registered Studies on the Promising Dipeptide Carnosine Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-07-27 Tilman Pfeffer, Dan Wen, Konstantinos Stefanidis, Verena Peters, Markus Ries
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Purification and Identification of Bioactive Oligopeptide from Indian Halibut (Psettodes erumei) Muscle Tissue and Its Inflammation Suppressing Effect In Vitro Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-07-22 Akshad Balde, Anushka Chatterjee, Saubhagya Shukla, Ila Joshi, Soottawat Benjakul, Se-Kwon Kim, Rasool Abdul Nazeer
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Designing a Novel Spike Linear B-Cell Epitopes (SLBE) Protein with High Performance in Sars-Cov2-ELISA Test Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-07-17 Majid Esmaelizad, Maedeh Hamidizadeh, Nazanin Esmaelizad, Mohammad Doroudian, Mohammad Ranjbar, Mohsen Lotfi
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Bacterial Peptides and Bacteriocins as Novel Treatment for Prostate Cancer Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-07-17 Keng Ye, Zunjin Ke, Xijiong Zhang, Ke Liang, Qi Zhang, Jianhong Huang
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Biological Stability of Peptides/Proteins Therapeutic Agents Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-07-17 Sara Salatin, Afsaneh Farjami, Mohammadreza Siahi-Shadbad, Samin Hamidi
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Why to Study Peptides from Venomous and Poisonous Animals? Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-07-14 Ana Novo de Oliveira, Andreimar Martins Soares, Saulo Luís Da Silva
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In silico Approach for B Cell Epitopes Prediction of Respiratory Syncytial Virus Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-07-13 Gayathri Anandhan, Yogesh B. Narkhede, Manikandan Mohan, Paramasivam Premasudha
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Antimicrobial Efficacy and Prevalence of Microcins: Low Molecular Mass Bacteriocins Produced by Escherichia coli Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-07-07 Farzaneh Mohammadzadeh Rostami, Sharareh Moghim, Saeid Javdan, Bahram Nasr Esfahani
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The Nuclear Localization Signal of NF-κB p50 Enters the Cells via Syndecan-Mediated Endocytosis and Inhibits NF-κB Activity Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-07-05 Annamária Letoha, Anett Hudák, Zsolt Bozsó, Csaba Vizler, Gábor Veres, László Szilák, Tamás Letoha
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Bioactive Peptides of Fermented Food Products Targeting the Structural Rigid Core of Amyloid Fibril Unravelled by Simulated Thermal Unfolding in Alzheimer’s Disorder Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-07-04 G. Chandrasekhar, R. Rajasekaran
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Biomedical and Nutritional Applications of Lactoferrin Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-07-04 Carlotta Coccolini, Elisa Berselli, Cristina Blanco-Llamero, Faezeh Fathi, M. Beatriz P. P. Oliveira, Karolline Krambeck, Eliana B. Souto
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A Review of Recent Advances in Peptide-Based Anticancer Therapeutic Vaccines and Nanovaccines in Prostate Cancer Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-07-04 Ali Khezrian, Mazaher Ahmadi, Pooneh Mokarram, Saeid Afshar, Yasin Parvizi
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Elucidation of the Mechanisms of Human cathelicidin-derived Antimicrobial Peptides (LL-37 and its Truncated LL-31) Against Burkholderia Pseudomallei Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-06-22 Onanong Phophetleb, Wonn Shweyi Thet Tun, Sompong Klaynongsruang, Sakda Daduang, Suwimol Taweechaisupapong, Rina Patramanon
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A Cicada Antimicrobial Peptide, Cryptonin, Exhibits Potent Antitumor Activity by Necrosis on Human Melanoma Cells Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-06-17 Serap Sancar, Gülşah Torkay, Tuba Çan
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Anticancer Potential and Cytotoxic Activity of NN-32, a Snake Venom Peptide, Against A549, Lung Cancer Cell Line Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-06-08 Pratibha Kurkute, Amol Jadhav, Sangeeta V. Pandit
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Isolation and Purification of an Oligopeptide from Periplaneta americana and Its Mechanism of Promoted Wound Healing Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-06-02 Yali Liu, Xueting Dai, Hanwen Hu, Jie Zhou, Yongqi Peng, Haimei Yuan, Qin Song
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Bioproduction and Characterization of Epinecidin-1 and Its Variants Against Multi Drug Resistant Bacteria Through In Silico and In Vitro Studies Int. J. Pept. Res. Ther. (IF 2.5) Pub Date : 2023-06-03 Sivakumar Jeyarajan, Aswathy Sathyan, Ansu Susan Peter, Sukumar Ranjith, Senbagam Duraisamy, Suriya Muthukumaran Natarajaseenivasan, Prahalathan Chidambaram, Anbarasu Kumarasamy