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The Role of Magnesium in Pregnancy and in Fetal Programming of Adult Diseases Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-12-14 Daniela Fanni, C. Gerosa, V. M. Nurchi, M. Manchia, L. Saba, F. Coghe, G. Crisponi, Y. Gibo, P. Van Eyken, V. Fanos, G. Faa
Magnesium is an essential trace metal and a necessary factor for multiple biochemical functions in humans. Its role in biology is fundamental in over 600 enzymatic reactions implicated in protein synthesis, mitochondrial functions, neuromuscular activity, bone formation, and immune system competence. Magnesium status is relevant in fetal development during gestation and in the newborn growth during
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Correction to: The Role of Nrf2 on the Cognitive Dysfunction of High-fat Diet Mice Following Lead Exposure Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-12-07 Lijin Zhang, Jianzhu Bo, Weiwei Chen, Shuang Li, Yan Wang, Licheng Yan, Lei Wu, Yanshu Zhang
A Correction to this paper has been published: https://doi.org/10.1007/s12011-020-02521-0
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The Immune Regulatory Effect of Boron on Ostrich Chick Splenic Lymphocytes. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-28 Xiaoting Zhang,Ke Xiao,Weiwei Qiu,Jiaxiang Wang,Peng Li,Kemei Peng
Boron is a trace element which plays important roles in immune response. The relationship between boron and splenic lymphocyte proliferation, apoptosis, secretion of cytokines, and genes potentially related to immune response in ostrich chicks were investigated in the present study. Different concentrations of boron (0, 0.01, 0.1, 0.5, 1, 5, 10, 25, 50, and 100 mmol/L) were applied to splenic lymphocytes
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Changes in Bone Turnover, Inflammatory, Oxidative Stress, and Metabolic Markers in Women Consuming Iron plus Vitamin D Supplements: a Randomized Clinical Trial. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-25 Behnaz Abiri,Mohammadreza Vafa,Fatemeh Azizi-Soleiman,Morteza Safavi,Seyyed Morteza Kazemi,Masood Salehi,Farid Zaeri,Homa Sadeghi
We aimed to investigate whether combination of vitamin D and iron supplementation, comparing vitamin D alone, could modify bone turnover, inflammatory, oxidative stress, and metabolic markers. Eighty-seven women with hemoglobin (Hb) ≤ 12.7 g/dL and 25OHD ≤ 29 ng/mL vitamin D deficiency/insufficiency aged 18-45 years were randomly assigned into two groups: (1) receiving either 1000 IU/day vitamin D3
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Correction to: Eco-Friendly Mycogenic Synthesis of ZnO and CuO Nanoparticles for In Vitro Antibacterial, Antibiofilm and Antifungal Applications. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-25 Asem A Mohamed,Mohammed Abu-Elghait,Nehad E Ahmed,Salem S Salem
The original version of this article unfortunately contained a mistake.
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Effects of Nano-selenium Poisoning on Immune Function in the Wumeng Semi-fine Wool Sheep. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-24 Yuanfeng Li,Jian He,Xiaoyun Shen
The Wumeng semi-fine wool sheep is vital to the production system in Southwest China. To study the effects of nano-selenium (Nano-Se) poisoning in the Wumeng semi-fine wool sheep, poisoning model was established. A total of 20 animals with an average initial body weight (BW) of 35.57 ± 3.31 kg were used in this study. After 1-week-long acclimatization period, all animals were randomly divided into
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Clinical Relevance of Serum Selenium Levels and Abdominal Aortic Calcification. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-24 Yu-Yang Lu,Wei-Liang Chen
Selenium (Se) is an essential micronutrient with antioxidative properties, but previous studies have shown that extremely high circulating Se concentrations are associated with a higher prevalence of cardiovascular diseases (CVDs). To date, it remains unknown whether this association has connections with arterial calcification. A total of 982 participants with both serum Se concentration and abdominal
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Effects of Dietary Supplementation with κ-Selenocarrageenan on the Selenium Accumulation and Intestinal Microbiota of the Sea Cucumbers Apostichopus japonicus. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-24 Kai Wang,Lina Liu,Yingying He,Changfeng Qu,Jinlai Miao
A 30-day feeding trial was conducted to investigate the effect of κ-selenocarrageenan on the growth performance, selenium accumulation, antioxidant capacity, and intestinal microbiota of sea cucumbers Apostichopus japonicus, with different sizes (70 g ± 10 g and 100 g ± 10 g). Sea cucumbers of each size were randomly assigned into two groups; a diet without supplemented κ-selenocarrageenan was referred
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Metals Distribution, Histopathological Alterations, and Health Risk Assessment in Different Tissues of Fish (Ctenopharyngodon idella). Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-24 Nazish Shah,Muhammad Khisroon,Said Sajjad Ali Shah
Grass carps were exposed to the established lethal concentration (LC) values of copper (Cu), chromium (Cr), and lead (Pb) each for the exposed period of 24, 48, 72, and 96 h respectively. Concentrations of these metals were determined in the brain, liver, muscles, gills, kidneys, and intestinal tissues of exposed and control fish through the atomic absorption spectrophotometer after the wet digestion
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Toxic Impacts of Amorphous Silica Nanoparticles on Liver and Kidney of Male Adult Rats: an In Vivo Study. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-22 Rehab A Azouz,Reda M S Korany
The toxic effects of the amorphous silica nanoparticles have not been thoroughly studied. Moreover, the majority of the in vivo investigations were performed using an inhalation exposure method. The current study aimed to explore the potential toxic effects of silica nanoparticles (SiNPs) after the treatment of adult male rats with two different concentrations (500 and 1000 ppm) via drinking water
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Sodium, Potassium, Calcium, and Magnesium in the Scalp Hair and Blood Samples Related to the Clinical Stages of the Parkinson's Disease. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-22 Kanwal Rajput,Hassan Imran Afridi,Tasneem Gul Kazi,Farah Naz Talpur,Jameel Ahmed Baig
Neurodegeneration disorders are complex and multifaceted, leading to many chronic diseases, like Parkinson's disease (PD). Electrolytes imbalance has a significant role in the pathophysiology of neurological disorders, which might serve as a bio-indicator of these problems. In the present study, the disturbances of the electrolytes, calcium (Ca), magnesium (Mg), sodium (Na), and potassium (K), concentrations
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Histopathological Evaluation of Spinal Cord with Experimental Traumatic Injury Following Implantation of a Controlled Released Drug Delivery System of Chitosan Hydrogel Loaded with Selenium Nanoparticle. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-22 Moosa Javdani,Roya Ghorbani,Mohammad Hashemnia
The purpose of this study was to evaluate the neuroprotective effect of local implantation of a controlled delivery system of chitosan hydrogel loaded with selenium nanoparticles in rats with spinal cord injury (SCI). For this purpose, 60 adult female rats were randomly divided into three equal groups. In all three groups, SCI was induced by aneurysm clamping at the level of thoracic vertebrae under
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Selenium Nutritional Status and Glutathione Peroxidase Activity and Its Relationship with Hemodialysis Time in Individuals Living in a Brazilian Region with Selenium-Rich Soil. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-22 Christielle Félix Barroso,Liliane Viana Pires,Larissa Bezerra Santos,Gilberto Simeone Henriques,Priscila Pereira Pessoa,Gueyhsa Nobre de Araújo,Camilla Oliveira Duarte de Araújo,Cláudia Maria Costa Oliveira,Carla Soraya Costa Maia
Suboptimal selenium status may impair the antioxidant defense system in patients undergoing hemodialysis, compromising the selenoenzyme glutathione peroxidase activity. To evaluate the association between the duration of hemodialysis, nutritional selenium status, glutathione peroxidase activity (GPx), and thiobarbituric acid reactive substance (TBARS) levels in patients with chronic renal failure undergoing
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Blood Lead, Systemic Inflammation, and Blood Pressure: Exploring Associations and Mediation Effects in Workers Exposed to Lead. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-21 Ping He,Chengxin Yang,Dongkui He,Shiyu Zhao,Yujia Xie,Haijiao Wang,Jixuan Ma
Relationships of lead exposure with blood pressure and blood lead with inflammation have been previously established yet, but the conclusions are still controversial. The objective of our study was to investigate the role of systemic inflammation in the relationships between blood lead concentration and blood pressure. We quantified the levels of blood lead and white blood cell count in 505 lead-exposed
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Randomized Study of the Effects of Vitamin D and Magnesium Co-Supplementation on Muscle Strength and Function, Body Composition, and Inflammation in Vitamin D-Deficient Middle-Aged Women. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-21 Fatemeh Kheyruri,Javad Sarrafzadeh,Agha Fatemeh Hosseini,Behnaz Abiri,Mohammadreza Vafa
This study aimed to investigate the effects of vitamin D and magnesium co-supplementation on muscle strength and function, body composition, and inflammation in vitamin D-deficient middle-aged women. In this study, 83 healthy middle-aged women (40-55 years) with vitamin D deficiency were randomly assigned into two groups: (1) intervention: receiving a 50,000-IU vitamin D soft gel (weekly) plus a 250-mg
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Cadmium Exposure and Testis Susceptibility: a Systematic Review in Murine Models. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-19 Janaina da Silva,Reggiani Vilela Gonçalves,Fabiana Cristina Silveira Alves de Melo,Mariáurea Matias Sarandy,Sérgio Luis Pinto da Matta
It is known that cadmium induces damage to the testis. However, the significant cadmium impact on the testicular architecture and the mechanisms involved in this process are not clear. Besides, the relationship between dose, route, and time of exposure and injuries remains poorly understood. Thus, we aimed to assess whether cadmium exposure in any dose, route, and time of exposure causes significant
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Serum Magnesium and Fractional Exhaled Nitric Oxide in Relation to the Severity in Asthma-Chronic Obstructive Pulmonary Disease Overlap. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-18 Mingzhi Ye,Qianhong Li,Ling Xiao,Zhongsheng Zheng
Serum concentrations of magnesium and manganese may be associated with increased chronic obstructive pulmonary disease exacerbation risk. However, associations with other aspects of asthma-chronic obstructive pulmonary disease overlap, pulmonary function test results and health status, have been studied less extensively. The aim of this study was to investigate the associations between serum concentrations
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Influence of Conventional or Invisalign Orthodontic Treatment on Mineral and Trace Element Salivary Levels: Longitudinal Study with Total Reflection X-ray Fluorescence. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-18 Aline Campos Zeffa,Bianca Gonçalves Dias,Daiane Cristina Mendonça Santos Silva,Luiz Orbolato Rotta,Eduardo Inocente Jussiani,Avacir Casanova Andrello,Solange de Paula Ramos
This work aimed to evaluate the salivary concentration of chemical elements in patients undergoing orthodontic treatment with fixed orthodontic appliances and removable aligners. Twelve Angle Class I and II orthodontic patients undergoing treatment with conventional fixed appliances and 15 patients treated with removable aligners provided unstimulated whole saliva samples before treatment (pre) and
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Association of Copper and Zinc Intake with Inflammatory Bowel Disease and Fecal Incontinence Symptoms: Evidence from the National Health and Nutrition Examination Survey. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-17 Lei Zhang,Feng Shao,Lijun Li
The associations between copper and zinc intake with the risk of inflammatory bowel disease (IBD) and fecal incontinence symptoms in the general population are not well understood. This study aims to evaluate the associations of zinc and copper intake with the risk of IBD and fecal incontinence symptoms in adults aged ≥ 20 years using data from the 2009-2010 National Health and Nutritional Examination
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Zinc Supplementation and Strength Exercise in Rats with Type 2 Diabetes: Akt and PTP1B Phosphorylation in Nonalcoholic Fatty Liver. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-16 Ariel Vivero,Manuel Ruz,Matías Rivera,Karen Miranda,Camila Sacristán,Alejandra Espinosa,Juana Codoceo,Jorge Inostroza,Karla Vásquez,Álvaro Pérez,Diego García-Díaz,Miguel Arredondo
Type 2 diabetes mellitus (T2D) is a metabolic disorder caused by chronic hyperglycemia due to a deficiency in the secretion and/or action of insulin. Zinc (Zn) supplementation and strength exercise increases insulin signaling. We evaluate the effect of Zn supplementation and strength exercise on insulin resistance in the liver of rats with diet-induced T2D through the study of phosphorylation of Akt
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Serum Iron and Ferritin Levels Are Correlated with Complement C3. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-15 Shuang Wen,Yeqin Sha,Yinling Li,Zhilian Rui,Chenhong Si,Yuning Zhou,Fengfeng Yan,Bicheng Wang,Jingming Hu,Xu Han,Dongyan Shi
Iron is one of the most important trace elements in the body, and its homeostasis is essential to the normal function of the immune system. Complement component C3, which is the converging of three main pathways of complement system activation, plays a key role in the innate immunity. However, the relationship between iron homeostasis and complement C3 remains unknown. The aim of our study was to analyze
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Lower Levels of Blood Zinc Associated with Intradialytic Hypertension in Maintenance Hemodialysis Patients. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-15 Yun Liu,Yuanyuan Zheng,Liangtao Wang,Xiaoshi Zhong,Danping Qin,Wenxuan Chen,Rongshao Tan,Yan Liu
Intradialytic hypertension (iHTN) has been related with an increased risk of mortality, with imbalances in trace elements being frequent in maintenance hemodialysis (MHD) patients. The aim of this study was to analyze the relationships between the levels of blood trace elements and iHTN in MHD patients. A total of 144 MHD patients were enrolled in September, 2019 (66 females; 5616 hemodialysis treatments)
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PbAc Triggers Oxidation and Apoptosis via the PKA Pathway in NRK-52E Cells. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-14 Duanya Liu,Jun Yu,Jie Xie,Zhaoyu Zhang,Caoli Tang,Tianmei Yu,Shouni Chen,Zhidan Hong,Chunhong Wang
This study aimed to investigate the mechanism of the lead exposure-induced oxidative stress and apoptosis of renal tubular epithelial cells. We explored the effects of lead acetate (PbAc) on the oxidation and apoptosis of renal proximal tubular cells (NRK-52E) through in vitro experiments. Results showed that PbAc induced dose-dependent reactive oxygen species (ROS) accumulation in NRK-52E cells, and
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Association Between Circulating Plasmacytoid Dendritic Cell Percentage and Blood Lead Levels in Children. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-12 Raghumoy Ghosh,Taru Goyal,Prasenjit Mitra,L Malavika,Shailja Sharma,Praveen Sharma
Lead (Pb) exposure is known to cause T helper 1 (Th1) to T helper 2 (Th2) shift in the immune response. The mechanism responsible for these effects is unclear. Plasmacytoid dendritic cells (pDCs) are known as the principal secretor of type 1 interferons (IFNs), which have a stimulatory effect on Th1 differentiation. However, no previous study has explored the effect of Pb on pDCs. Thus, the present
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Assessment of Heavy Metal Contamination and the Probabilistic Risk via Salad Vegetable Consumption in Tabriz, Iran. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-12 Arezou Khezerlou,Parvin Dehghan,Mir-Hassan Moosavy,Hojjat Kochakkhani
Considering the importance of vegetables as a source of micronutrients and fibers in a balanced diet, there is still a concern that vegetables could also be a source of toxic heavy metal contaminants. The study aimed to determine the concentrations of lead (Pb), cadmium (Cd), arsenic (As), chromium (Cr), copper (Cu), nickel (Ni), and zinc (Zn) in the salad vegetables sold in Tabriz city, Iran, and
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Evaluation of the Effects of Aging on the Aorta Stiffness in Relation with Mineral and Trace Element Levels: an Optimized Method via Custom-Built Stretcher Device. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-12 Duygu Aydemir,Naveed Salman,Mehrdad Karimzadehkhouei,B Erdem Alaca,Belma Turan,Nuriye Nuray Ulusu
Aortic stiffness represents the major cause of aging and tightly associated with hypertension, atherosclerosis, cardiovascular diseases, and increased mortality. Mechanical characteristics of the aorta play a vital role in the blood flow, circulation, systolic pressure, and aortic stiffness; however, the correlation of trace element and mineral levels with aortic stiffness has not been studied before
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Multiple Chemosensory Neurons Mediate Avoidance Behavior to Rare Earth Ions in Caenorhabditis elegans. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-10 Tokumitsu Wakabayashi,Yui Nojiri,Miwa Takahashi-Watanabe
As rare earth (RE) metals are abundantly present in the soil, in spite of their name, it is conceivable that organisms may encounter and interact with RE ions. In the present study, we demonstrated that the soil nematode Caenorhabditis elegans avoids RE ions, such as yttrium and all examined lanthanide ions, which exhibit toxic effects on nematodes. We also demonstrated that the chemosensory system
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Protective Effect of Boric Acid and Omega-3 on Myocardial Infarction in an Experimental Rat Model. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-09 Hadi Karimkhani,Mete Özkoç,Paria Shojaolsadati,Kubilay Uzuner,Dilek Burukoglu Donmez,Güngör Kanbak
Boric acid and omega-3 are used as essential elements for both animal and human health. Many researchers have shown these beneficial effects on cardiac and inflammatory markers. This study aims to evaluate cardiac protective effect of boric acid and omega-3 against MI (myocardial infarction), probably due to the suppression of pro-inflammatory cytokines of natriuretic peptides in rats. Fifty male Sprague-Dawley
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Safety Assessments of Nickel Boride Nanoparticles on the Human Pulmonary Alveolar Cells by Using Cell Viability and Gene Expression Analyses. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-09 Hasan Türkez,Mehmet Enes Arslan,Erdal Sönmez,Abdulgani Tatar,Fatime Geyikoğlu,Metin Açikyildiz,Adil Mardinoğlu
Nickel boride is generally used in the steel industry as a melting accelerator due to its feature of creating a protective and stable attribute at high temperatures. It is also used to improve the hardenability of the steel with boron addition in the production. Thus, safety studies and biocompatibility analysis of nickel boride should be performed comprehensively to understand the limitations of use
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A Review on the Serum Electrolytes and Trace Elements Role in the Pathophysiology of COVID-19. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-08 Mohammad Taheri,Ali Bahrami,Parisa Habibi,Fatemeh Nouri
All the world is involved in the COVID-19 disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Coronavirus is a positive-sense RNA and has an envelope. There is no specific drug for this disease and treatment methods are limited. Malnutrition and electrolyte imbalance can make dysfunction in the immune system and impairment of the immune system causes increasing the risk
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Trace Elements in the Large Population-Based HUNT3 Survey. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-08 Tore Syversen,Lars Evje,Susann Wolf,Trond Peder Flaten,Syverin Lierhagen,Anica Simic
The Nord-Trøndelag Health Study (The HUNT Study) is a large health survey population study in the county of Trøndelag, Norway. The survey has been repeated four times in about 10-year intervals. In the HUNT3 survey (2006-2008), we collected 28,000 samples for trace element analysis. Blood samples from 758 healthy persons without known occupational exposure were selected for multielement analysis of
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Eco-friendly Mycogenic Synthesis of ZnO and CuO Nanoparticles for In Vitro Antibacterial, Antibiofilm, and Antifungal Applications. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-08 Asem A Mohamed,Mohammed Abu-Elghait,Nehad E Ahmed,Salem S Salem
Mycogenic synthesis of medically applied zinc oxide (ZnO) and copper oxide (CuO) nanoparticles (NPs) were exploited using Penicillium chrysogenum. The biogenesis and capping processes of the produced nano-metals were conducted by functional fungal extracellular enzymes and proteins. The obtained ZnO-NPs and CuO-NPs were characterized. Also, the antibacterial activity and minimum inhibitory concentration
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Index of Nutritional Quality (INQ) and the Risk of Obesity in Male Adolescents: a Case-Control Study. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-07 Maryam Gholamalizadeh,Samira Rastgoo,Saeid Doaei,Farhad Vahid,Hanieh Malmir,Narges Ashoori,Alireza Mosavi Jarrahi
Dietary factors may play a key role in the etiology of obesity. The Index of Nutritional Quality (INQ) provides a comprehensive overview of the nutrients content of the diet. This study aimed to investigate the association between INQ and obesity in male adolescents. We hypothesize that receiving a high-quality diet reduces the risk of overweight or obese. This study was carried out on 214 obese/overweight
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Trace and Major Elements Concentration in Fish and Associated Sediment-Seawater, Northern Shores of the Persian Gulf. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-07 Mehdi Bibak,Masoud Sattari,Saeid Tahmasebi,Raheleh Kafaei,George A Sorial,Bahman Ramavandi
The concentration of 19 metal and non-metal elements in two fishes (Liza subviridis and Sphyraena jello) and associated sediment-seawater from the northern part of the Persian Gulf was measured. The samples were gathered from two industrial ports, one commercial port, and one residential port. The metal accumulation in the muscle and liver of fishes was evaluated. Nickel (mean 362.07-712.83 μg/g) and
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Correction to: Ortho-silicic Acid Inhibits RANKL-Induced Osteoclastogenesis and Reverses Ovariectomy-Induced Bone Loss In Vivo. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-07 Wenzheng Ma,Fu'an Wang,Yunhao You,Wenliang Wu,Hai Chi,Guangjun Jiao,Lu Zhang,Hongming Zhou,Hongliang Wang,Yunzhen Chen
The original version of this article unfortunately contained a mistake. The name of "Yunzhen Chen" is now corrected in the author group.
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Chromium Exposure in Late Gestation Period Caused Increased Levels of Cr in Brain Tissue: Association with Alteration of Activity and Gene Expression of Antioxidant Enzymes of F1 and F2 Generation Mice. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-05 Sumita Halder,Rajarshi Kar,Sucharita Chakraborty,Basu D Banerjee
Chromium is a micronutrient which has found frequent use as supplements during pregnancy and could have a role in altering the antioxidant status in the brain. The present study was undertaken to estimate chromium levels in the brain, antioxidant enzyme activity with their gene expression, and learning and memory parameters on F1 and F2 generation mice when the F0 was exposed to chromium. The chromium
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The Determination of Toxic Metals in some Traditional Cosmetic Products and Health Risk Assessment. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-05 Serpil Kilic,Murat Kilic,Mustafa Soylak
In present study, the levels of some toxic elements in 19 different home-made cosmetic products (spray hair dye, henna, tattoo, eyeliner, eye mascara, smear, lip moisturizer, and lipstick) were analyzed by inductively coupled plasma mass spectrometric (ICP-MS) after microwave digestion. The ICP-MS results were verified by the analyzing certificated reference material (EnviroMAT Drinking Water, High)
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Serum Concentrations of Trace Elements/Minerals in Patients with Diffuse Systemic Sclerosis. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-03 Xia Li,Xiujuan Wang,Jin Li,Shanshan Liu,Zheng Liu
Trace elements and minerals are essential for cellular physiology and components of biological structures. Previous studies demonstrated that proper serum concentration of trace elements/minerals such as copper maintains optimum function of the immune system, and trace elements/mineral imbalance was associated with various autoimmune disorders. The current study aimed to measure the serum concentrations
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Calcium Fructoborate Prevents Skin Cancer Development in Balb-c Mice: Next Part, Reverse Inflammation, and Metabolic Alteration. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-03 Mehmet Ali Kisacam,Gonca Ozan Kocamuftuoglu,Ibrahim Enver Ozan,Mehmet Yaman,SemaTemizer Ozan
Metabolic alterations and inflammation are regarded as hallmarks of cancer. Glycolytic flux and intermediate accumulation lead to the production of building blocks and NADPH which is important in protecting the cell from oxidative damage. Inflammation causes the release of mediators responsible for regulating molecular mechanism affecting metabolic pathways. CaFB due to its cis-diol-rich feature may
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Uptake and Distribution Characteristic and Health Risk Assessment of Heavy Metal(loid)s in Platycodon Grandiflorum (Jacq.) A.DC. with Growth from a Medicinal Herb Garden of Xi'an, China. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-09-01 Guanjun Nan,Xianxin Meng,Ning Song,Zhengzheng Liu,Yu Liu,Yunzhe Li,Guangde Yang,Shaohua Zheng
The different parts of Platycodon grandiflorum were collected from a medicinal herb garden to determine five heavy metal(loid)s (Pb, Cd, As, Hg, and Cu) contents at different growth stages. The data showed that the plant accumulated varying amounts of metal(loid)s in the order Cu > Hg > Pb > As > Cd. Five heavy metal(loid) concentrations decreased in the early growth stage and then increased in the
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Comparison of Free Zinc Levels Determined by Fluorescent Probes in THP1 Cells Using Microplate Reader and Flow Cytometer. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-08-31 Wiebke Alker,Hajo Haase
Free zinc is involved in signal transduction within mammalian cells, acting as a second messenger. Gold standard for its analysis is currently the use of metal-responsive fluorescent probes. The present study elucidates the impact of instrumentation used for measuring the resulting fluorescence. The free zinc concentration of THP-1 cells loaded with the fluorescent probes Zinpyr-1 (ZP1) or Fluozin-3
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High Blood Lead Levels: An Increased Risk for Development of Brain Hyperintensities among Type 2 Diabetes Mellitus Patients. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-08-31 Hafsa Suhail Najim Al-Anbari,Dawser K Ismail,Mohammed Khudair Hasan,Qutaiba Ahmed Al Khames Aga,Pottathil Shinu,Anroop B Nair
The current study was aimed to ascertain the effect of blood lead level on brain tissues in patients with type 2 diabetes. A total of 300 human participants ages 27 to 60 years with type 2 diabetes (n = 150) and healthy individuals (n = 150) were included in this study. The serum samples were used for measuring HbA1c and fasting blood glucose. Blood lead level was measured using flame atomic absorption
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Fluoride-Induced Expression of Neuroinflammatory Markers and Neurophysiological Regulation in the Brain of Wistar Rat Model. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-08-31 Yugandhar P Reddy,Santosh Tiwari,Lomas K Tomar,Nalini Desai,Varun Kumar Sharma
Excess fluoride intake has been linked with various pathological conditions. The objective of the present study was to understand the role of fluoride in neurotoxic, neuroinflammatory, and neurodegenerative changes in the brain tissue of Wistar rats. Wistar rats were fed with water containing 20-100 ppm (ppm) sodium fluoride (NaF). An array of neurotransmitters (acetylcholine, dopamine, epinephrine
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Statistical Approach and Neutron Activation Analysis for Determining Essential and Toxic Elements in Two Kinds of Algerian Artemisia Plant. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-08-29 Samir Begaa,Mohammed Messaoudi,Adel Benarfa
In this study, two kinds of Artemisia plant, Artemisia campestris L. and Artemisia herba-alba Asso., collected from different locations in Djelfa province, Algeria, were subjected to an instrumental neutron activation analysis (INAA) in order to determine their essential and toxic elements for the first time. The obtained results for both types revealed the existence of twenty-one elements, namely
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Comparison of Zinc Sulfate and Zinc Threonine Based on Zn Bioavailability and Performance of Broiler Chicks. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-08-28 Siavash Farhadi Javid,Hossein Moravej,Mohammad Ghaffarzadeh,Mohammad Behjatian Esfahani
The purpose of this study was to compare zinc sulfate and zinc threonine chelate based on Zn bioavailability and performance of broiler chicks. The study was conducted in a completely randomized design with 256 day-old Ross 308 chicks and eight treatments including control treatment (no zinc supplementation), three levels of zinc sulfate and zinc threonine chelate (40, 80, and 120 mg zinc per kg feed)
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Swarna Bindu Prashana-an Ancient Approach to Improve the Infant's Immunity. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-08-27 Prabhudas Nelaturi,Prithiviraj Nagarajan,Satheesh Kumar Sabapathy,Ravikumar Sambandam
Swarna bindu prashana (SBP) is a metallic medicinal preparation widely used in Ayurveda pediatrics. The main ingredients of SBP are swarna prashan (gold nanoparticle), gou ghrita (cow ghee), madhu (honey), and other medhya dravyas (drugs which enhance intellectual, memory). According to the Indian classical text, SBP has been proposed as a potent medicine for immunotherapies and vaccine development
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Fluoride and Biological Calcification I: Effect of Fluoride on Collagen-Induced In Vitro Mineralization and Demineralization Reactions. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-08-27 Monica Kakkar,Vivek Kapoor,S K Singla,R K Jethi
An in vitro system employing collagen isolated from the sheep tendons to induce mineralization and demineralization reactions was used not only to study the effect of various concentrations of fluoride on the collagen-induced mineralization and demineralization reactions but also to compare their action with the inhibitors of mineralization and/or demineralization. Studies demonstrated that under physiological
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Maternal Urinary Iodine Concentration and Pregnancy Outcomes: Tehran Thyroid and Pregnancy Study. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-08-27 Zheng Feei Ma
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Effectiveness of Zinc Supplementation on Lithium-Induced Alterations in Thyroid Functions. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-08-26 Rajiv Pathak,Ashima Pathak
Lithium is an integral drug used in the management of acute mania, unipolar and bipolar depression, and prophylaxis of bipolar disorders. Thyroid abnormalities have been associated with treatment with lithium. Zinc is an essential trace element that plays a role in several biological activities. Therefore, the present study was aimed at investigating the potential role of zinc in the thyroid gland
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Nanoselenium and Selenium Yeast Have Minimal Differences on Egg Production and Se Deposition in Laying Hens. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-08-26 Tian-Tian Meng,Xue Lin,Chun-Yan Xie,Jian-Hua He,Yang-Kui Xiang,Yi-Qiang Huang,Xin Wu
The objective of this study was to compare the effects of nanoselenium (NS) and selenium yeast (SY) on the performance, egg selenium (Se) concentration, and anti-oxidative capacity of hens. A total of 216 Brown Hy-line hens (29-week old) were randomly allocated into three treatments (6 replicate/treatment, 12 hens/replicate). The pre-trial period lasted 7 days, and the experimental period lasted 35
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Zinc Modulates the Response to Apoptosis in an In Vitro Model with High Glucose and Inflammatory Stimuli in C2C12 Cells. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-08-25 Mónica Andrews-Guzmán,Manuel Ruz,Miguel Arredondo-Olguín
Apoptosis is programmed cell death and its alteration is related to cancer, neurologic, autoimmune, and chronic diseases. A number of factors can affect this process. The aim of this paper is to study the effect of supplemental zinc on apoptosis-related genes in C2C12 myoblast cells after being challenged with a series of stimuli, such as high glucose, insulin, and an inflammatory agent. C2C12 myoblast
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Zinc Oxide Nanoparticle Induces Apoptosis in Human Epidermoid Carcinoma Cells Through Reactive Oxygen Species and DNA Degradation. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-08-25 Mohd Jahir Khan,Abrar Ahmad,Mahmood Ahmad Khan,Sahabjada Siddiqui
Zinc oxide nanoparticles (ZnO-NPs) are used immensely in technology and medicine, but very less is known about toxicity mechanism to human epidermal cells. The objective of this study was to evaluate possible anticancer properties of ZnO-NPs on human epidermoid carcinoma cells using MTT assay, measurement of reactive oxygen species, DNA fragmentation, and nuclear condensation. ZnO-NPs were synthesized
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Nickel Content in Human Internal Organs. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-08-24 Danuta Dudek-Adamska,Teresa Lech,Tomasz Konopka,Paweł Kościelniak
With the growing interest in new applications of metals in modern technologies, an increase in their concentration in the environment can be observed, which, in consequence, may constitute a hazard to human health. That is why it is of a great importance to establish "reference" levels of particular elements (essential or toxic) in human biological samples.The aim of this paper was to determine nickel
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The Joint Role of Iodine Status and Thyroid Function on Risk for Preeclampsia in Finnish Women: a Population-Based Nested Case-Control Study. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-08-21 Elijah C Reische,Tuija Männistö,Alexandra Purdue-Smithe,Kurunthachalam Kannan,Un-Jung Kim,Eila Suvanto,Heljä-Marja Surcel,Mika Gissler,James L Mills
Preeclampsia, a pregnancy disorder that includes hypertension and proteinuria, is a major cause of maternal and fetal morbidity and mortality. Some studies, but not all, have found that women with preeclampsia have significantly lower iodine levels than healthy pregnant women. Resolving this issue is important because iodine deficiency in pregnancy is common in the USA and parts of Europe including
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Probiotics: a Promising Generation of Heavy Metal Detoxification. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-08-21 Rehab M Abdel-Megeed
Different environmental toxins especially heavy metals exist in soil, water, and air recording toxic effect on human, animal, and plant. These toxicant elements are widespread in environment causing various disturbances in biological systems. Numerous strategies have been applied recently to alleviate heavy metal contamination; however, most of these strategies were costly and seemed unfriendly to
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Zinc Supplementation Restores Altered Biochemical Parameters in Stomach Tissue of STZ Diabetic Rats. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-08-20 Ismet Burcu Turkyilmaz,Bertan Boran Bayrak,Ozlem Sacan,Ozgur Mutlu,Nuriye Akev,Refiye Yanardag
The stomach is among the organs grossly affected organ by diabetic complications. The present study was aimed at investigating the protective role of zinc on stomach of streptozotocin (STZ)-induced diabetes mellitus. Female Swiss albino rats were divided in four experimental groups: Group I, control; group II, control + zinc sulfate; group III, STZ-induced diabetic animals; and group IV, STZ-diabetic
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Osteogenesis Promotion of Selenium-Doped Hydroxyapatite for Application as Bone Scaffold. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-08-20 Solmaz Zakhireh,Khosro Adibkia,Younes Beygi-Khosrowshahi,Mohammad Barzegar-Jalali
The combined bioceramic of selenium (Se) and hydroxyapatite (HA) has been considered as a moderate bone scaffold biomaterial. In the present work, Se was doped into the HA structure using the mechano-chemical alloying (MCA) method for the improvement of osteogenic properties of HA. HA extracted from fish bone and Se-doped hydroxyapatite (Se-HA) were analyzed using X-ray diffraction spectra (XRD), scanning
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The Effects of Metal Exposures on Charlson Comorbidity Index Using Zero-Inflated Negative Binomial Regression Model: NHANES 2011-2016. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-08-20 Hantong Zhao,Yingan Pan,Changcong Wang,Yinpei Guo,Nan Yao,Han Wang,Bo Li
BACKGROUND With the rising incidence of chronic diseases, and the increase of aging population has led to multimorbidity a serious public health problem. The aim of this study was to explore the association between metal exposures and Charlson comorbidity index (CCI), which will provide valuable information for improving quality of life and reducing mortality. METHODS The study sample consists of three
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Correction to: Protective Effects of an Oxovanadium(IV) Complex with N2O2 Chelating Thiosemicarbazone on Small Intestine Injury of STZ-Diabetic Rats. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-08-20 Sevim Tunali,Selda Gezginci-Oktayoglu,Sehnaz Bolkent,Ediz Coskun,Tulay Bal-Demirci,Bahri Ulkuseven,Refiye Yanardag
The original version of this article unfortunately contained a mistake. In Table 2, last column, the header should be Na+/K+-ATPase.
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Biologically Active Substance Content in Edible Plants of Zakarpattia and Their Elemental Composition Model. Biol. Trace Elem. Res. (IF 2.639) Pub Date : 2020-08-19 Tamara Meleshko,Roman Rukavchuk,Larysa Buhyn