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Quality assessment of leaf extracts of 12 olive cultivars and impact of seasonal variation based on UV spectroscopy and phytochemcial content using multivariate analyses Phytochem. Anal. (IF 2.772) Pub Date : 2021-02-23 Eman M. Kabbash; Iriny M. Ayoub; Haidy A. Gad; Zeinab T. Abdel‐Shakour; Sherweit H. El‐Ahmady
Recently, focus has been made on the health‐oriented uses of olive leaves, a byproduct of olive production, as a potential source of antioxidants. Oleuropein is one of the phenolic components in olive leaves known for its high antioxidant value.
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LC–MS/MS coupled with chemometric analysis as an approach for the differentiation of bulbus Fritillaria unibracteata and Fritillaria ussuriensis Phytochem. Anal. (IF 2.772) Pub Date : 2021-02-22 Lin Yang; Mengrui Zhang; Tiechui Yang; Tse Wai Ming; Tse Kathy Wai Gaun; Bengui Ye
Bulbus Fritillaria unibracteata Hsiao et K.C. Hsia is an important traditional Chinese medicine, widely used for the treatment of coughs, phlegm and asthma for thousands of years. Due to an increasing demand in clinic practices, a variety of substitutes have appeared in the market, resulting in a big challenge in the differentiation of bulbus F. unibracteata and its substitutes.
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Identifying new compounds with potential pharmaceutical and physiological activity in Areca catechu and Areca triandra via a non‐targeted metabolomic approach Phytochem. Anal. (IF 2.772) Pub Date : 2021-02-22 Jiao Wu; Chuang Cui; He Zhang; Dongjun Liu; Lukas Schreiber; Weiquan Qin; Yinglang Wan
The fruits of Areca catechu, also called areca nuts, are widely used as popular masticatory and traditional herbal medicine in Asia. Besides arecoline and related alkaloids, limited information is available about further primary and secondary metabolites and their potential biological activities.
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In vivo anti‐inflammatory activity of Fabaceae species extracts screened by a new ex vivo assay using human whole blood Phytochem. Anal. (IF 2.772) Pub Date : 2021-02-16 Welton Rosa; Olívia da Silva Domingos; Paula Pio de Oliveira Salem; Ivo Santana Caldas; Michael Murgu; João Henrique Ghilardi Lago; Patricia Sartorelli; Danielle Ferreira Dias; Daniela Aparecida Chagas‐Paula; Marisi Gomes Soares
Plants have been considered a promising source for discovering new compounds with pharmacological activities. The Fabaceae family comprises a large variety of species that produce substances with diverse therapeutic potential, including anti‐inflammatory activity. The limitations of current anti‐inflammatories generate the need to research new anti‐inflammatory structures with higher efficacy as well
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Discrimination between Zingiberis Rhizoma Praeparatum and carbonised ginger by colour measurement and fingerprint analysis Phytochem. Anal. (IF 2.772) Pub Date : 2021-02-16 Chang Deng; Rong Xue; Jing Wang; Ming Cheng; Guangfei Zhu; Kewei Zhang; Tulin Lu; Chunqin Mao
Zingiberis Rhizoma (ZR) has been used as a traditional Chinese herb and culinary food for thousands of years. Its two processed products, Zingiberis Rhizoma Praeparatum (ZRP) and carbonised ginger (CG), possess different therapeutic effects.
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Optimisation of microwave‐assisted extraction and functional elucidation of bioactive compounds from Cola nitida pod Phytochem. Anal. (IF 2.772) Pub Date : 2021-02-14 Olusegun Abayomi Olalere; Chee‐Yuen Gan; Olumide Esan Akintomiwa; Oladayo Adeyi; Abiola Adeyi
The quality characteristics and stability of phenolic by‐products from Cola nitida wastes are critical factors for drug formulation and food nutraceutical applications.
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Issue Information Phytochem. Anal. (IF 2.772) Pub Date : 2021-02-14
No abstract is available for this article.
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Attenuated total reflectance–Fourier transform infrared (ATR–FTIR) spectroscopy coupled with chemometric analysis for detection and quantification of adulteration in lavender and citronella essential oils Phytochem. Anal. (IF 2.772) Pub Date : 2021-02-10 Eleonora Truzzi; Lucia Marchetti; Davide Bertelli; Stefania Benvenuti
The growing consumer interest in “naturals” led to an increased application of essential oils (EOs). The market outbreak induced the intensification of EO adulterations, which could affect their quality.
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Identification of flavonoid‐3‐O‐glycosides from leaves of Casearia arborea (Salicaceae) by UHPLC‐DAD‐ESI‐HRMS/MS combined with molecular networking and NMR Phytochem. Anal. (IF 2.772) Pub Date : 2021-02-08 Augusto L. Santos; Marisi G. Soares; Lívia S. de Medeiros; Marcelo J.P. Ferreira; Patricia Sartorelli
Casearia is an essential source of cytotoxic highly oxidised clerodane diterpenes, in addition to phenolics, flavonoids, and glycoside derivatives. Here we identify flavonoid‐3‐O‐glycoside derivatives in the ethyl acetate (EtOAc) fraction of the methanolic extract from leaves C. arborea leaves.
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DNA meta‐barcoding using rbcL based mini‐barcode revealed presence of unspecified plant species in Ayurvedic polyherbal formulations Phytochem. Anal. (IF 2.772) Pub Date : 2021-02-01 Ramesh Pandit; Tasnim Travadi; Sonal Sharma; Chaitanya Joshi; Madhvi Joshi
Ayurveda takes advantage of the beneficial properties of medicinal plants. High demands in combination with inadequate availability of botanicals and a lack of knowledge with respect to their precise identification lead to adulterations in herbal products. Identification becomes more difficult in complex herbal formulations. Four different polyherbal formulations have been analyzed for the present
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Cleavage rules of mass spectrometry fragments and rapid identification of chemical components of Radix Paeoniae Alba using UHPLC‐Q‐TOF‐MS Phytochem. Anal. (IF 2.772) Pub Date : 2021-01-27 Shenshen Yang; Xinyue Zhang; Yaqian Dong; Guijiang Sun; Aili Jiang; Yubo Li
Radix Paeoniae Alba (RPA) presents several pharmacological effects, including analgesia, liver protection, and toxicity reduction. RPA consists mostly of monoterpenes and their glycosides, tannins, flavonoids, and organic acids, with monoterpenes being the main active pharmaceutical ingredients.
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Multivariate statistical and comparison analysis of chemical constituents in Arenaria kansuensis Maxim. from different regions in Qinghai‐Tibet Plateau Phytochem. Anal. (IF 2.772) Pub Date : 2021-01-26 Zenggen Liu; Mingzhu Li; Yanduo Tao; Richard Olsen
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Determination of monosaccharides in Lycium barbarum fruit polysaccharide by an efficient UHPLC‐QTRAP‐MS/MS method Phytochem. Anal. (IF 2.772) Pub Date : 2021-01-21 Jun Xu; Rui Wang; Junlin Liu; He Cheng; Daiyin Peng; Lihua Xing; Suying Shi; Nianjun Yu
Pre‐column derivatisation using 1‐phenyl‐3‐methyl‐5‐pyrazolone (PMP) is a common method for monosaccharide determination. Herein, a specific ultra‐high‐performance liquid chromatography quadrupole trap tandem mass spectrometry (UHPLC‐QTRAP‐MS/MS) method was developed and used for the determination of monosaccharide composition of Lycium barbarum polysaccharide (LBP).
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Phytochemical discrimination of Pinus species based on GC–MS and ATR‐IR analyses and their impact on Helicobacter pylori Phytochem. Anal. (IF 2.772) Pub Date : 2021-01-18 Haidy Gad; Eman Al‐Sayed; Iriny Ayoub
The leaves and cones of Pinus plants as well as their essential oils have been used in traditional medicine for the treatment of several ailments.
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Metabolic differences of two Ferula species as potential sources of galbanum: An NMR‐based metabolomics study Phytochem. Anal. (IF 2.772) Pub Date : 2021-01-17 Faegheh Farhadi; Mehrdad Iranshahi; Leila Mohtashami; Shokrollah Shakeri Asil; Milad Iranshahy
Ferula gummosa Boiss. and Ferula galbaniflua Boiss. & Buhse (Apiaceae) are two important Iranian plants that are considered as potential sources of galbanum (barijeh). Galbanum is traditionally used for treating different diseases including flatulence and memory impairment.
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Analysis of arglabin and its derivatives using high‐performance liquid chromatography Phytochem. Anal. (IF 2.772) Pub Date : 2021-01-06 Sergazy M. Adekenov; Saltanat T. Shamilova; Ilya A. Khabarov
The chemical modification of arglabin, a natural sesquiterpene lactone, has garnered significant attention because it comprises a guaianolide structure that exhibits antitumour and immunomodulating properties. Its primarily derived from Artemisia glabella Kar. et Kir. Physicochemical characterisation of commercial anititumour drugs based on arglabin can be time‐consuming and expensive; thus, high‐performance
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A useful quality control using herbal volatiles of Artemisia princeps Pamp. cv. ssajuari (ssajuari‐ssuk; Korean mugwort) according to air‐drying time by fast gas chromatography with uncoated surface acoustic wave sensor (Electronic zNose) Phytochem. Anal. (IF 2.772) Pub Date : 2020-12-22 Se Yeon Oh
Korean mugwort has been used as a traditional medicine. Specifically, air‐dried Artemisia princeps Pamp. cv. ssajuari (ssajuari‐ssuk; Korean mugwort) has been used as moxa in moxibustion therapy. Thus, the evaluation of high quality ssajuari‐ssuk containing herbal volatiles is of great interest in clinical therapy and the food industry.
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The composition differences between small black beans and big black beans from different habitats and its effects on the processing of Polygonum multiflorum Phytochem. Anal. (IF 2.772) Pub Date : 2020-12-17 Wanning Chen; Piao Wang; Hongxi Chen; Yanchao Xing; Caixiang Liu; Guixiang Pan; Zhiying Dou; Lifeng Han
The roots of Polygonum multiflorum (PM) serve as a classical traditional Chinese medicine (TCM), which has multiple biological activities. However, many cases of hepatotoxicity in PM have been reported in recent years. Processing PM with black beans decoction is one of the typical processing methods to reduce the hepatotoxicity of PM since ancient times.
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Development of a LC–HRMS based approach to boost structural annotation of isomeric citrus flavanones Phytochem. Anal. (IF 2.772) Pub Date : 2020-12-16 Ying‐Jie He; Ying Zhou; Yan Qin; Zhong‐Shun Zhou; Meng Zhu; Yan‐Yan Zhu; Zhao‐Jie Wang; Tian‐Zhen Xie; Li‐Xing Zhao; Xiao‐Dong Luo
The structural annotation of target relies on high‐resolution mass spectrometry (HRMS) information resulting in dubious identities in most cases. The accurate annotation of isomeric structures is still challenging to be confirmed with significant bottleneck.
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Issue Information Phytochem. Anal. (IF 2.772) Pub Date : 2020-12-16
No abstract is available for this article.
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Quantitative 1H nuclear magnetic resonance (qHNMR) methods for accurate purity determination of glucosinolates isolated from Isatis indigotica roots Phytochem. Anal. (IF 2.772) Pub Date : 2020-10-30 Qihui Guo; Zeyun Li; Lulu Shen; Ying Xiao; Zhihong Cheng
Glucosinolates (1–5) are important secondary metabolites found in Isatis indigotica roots. Due to their high hydrophilic and ionic nature, purified glucosinolates often contain salt impurities and moisture. Accurate assessment of their purities is important for glucosinolates being utilised as chemical markers.
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Isothermal kinetics of ethanolic extraction of total hypericin from pre‐extracted Hypericum perforatum flowers Phytochem. Anal. (IF 2.772) Pub Date : 2020-12-14 Borivoj Adnadjevic; Biljana Koturevic; Jelena Jovanovic
Hypericum perforatum L., Hypericaceae (St John's wort) is a highly familiar plant in the medicinal community which recently showed good antiviral activities including against some types of coronavirus.
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Correlations between phytochemical fingerprints of Moringa oleifera leaf extracts and their antioxidant activities revealed by chemometric analysis Phytochem. Anal. (IF 2.772) Pub Date : 2020-12-14 Yongbing Xu; Guilin Chen; Mingquan Guo
Moringa oleifera Lam. is widely cultivated and applied in tropical and subtropical areas. Numerous studies have been focused on the antioxidant capacity of M. oleifera leaves, but its correlated bioactive phytochemicals remain elusive.
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Gene‐targeted molecular phylogeny, phytochemical analysis, antibacterial and antifungal activities of some medicinal plant species cultivated in Egypt Phytochem. Anal. (IF 2.772) Pub Date : 2020-12-11 Hanaa S. Omar; Tarek R. Elsayed; Nour El‐Houda A. Reyad; Israa. M. Shamkh; Mohamed S. Sedeek
Medicinal plants have been used in healthcare since time immemorial, as have their therapeutic activities and the production of plant‐based medicines.
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Metabolomic analysis reveals the valuable bioactive compounds of Ardisia elliptica Phytochem. Anal. (IF 2.772) Pub Date : 2020-12-08 Pei Lou Wong; Nurul Shazini Ramli; Chin Ping Tan; Azrina Azlan; Faridah Abas
Ardisia elliptica Thunb. (Primulaceae) is a medicinal herb that is traditionally used for the treatment of fever, diarrhoea, measles and herpes. However, there is limited information regarding the correlation of its phytoconstituents with the bioactivity. Optimisation of solvent extraction is vital for maximising retention of bioactive molecules.
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Simultaneous quantitation of kavalactones in kava dry extracts: comparison of multi‐standards and single standard validation approaches Phytochem. Anal. (IF 2.772) Pub Date : 2020-12-07 Juliana Veloso Ferreira; Isabella Campolina Pierotte; Gerson Antônio Pianetti; Isabela Costa César
Dried extracts of Piper methysticum G. Forst, also known as kava, has been widely used due to its anxiolytic and sedative properties. In order to assure the quality of these extracts, it is essential to accurately quantify kavalactones, known as the active principle.
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On‐line coupling pressurised liquid extraction with two‐dimensional counter current chromatography for isolation of natural acetylcholinesterase inhibitors from Astragalus membranaceus Phytochem. Anal. (IF 2.772) Pub Date : 2020-11-25 Sainan Li; Chunming Liu; Yuchi Zhang; Rong Tsao
Radix Astragali, the dried root of Astragalus membranaceus (Fish.) Bge. (family Fabaceae), which is known as Huangqi in China, has been proven to be an immunostimulant, diuretic, antidiabetic, analgesic, and it has also been used as a health food supplement in some Asian populations and also serves as a lead herb in many traditional Chinese medicine formulations as well as in Chinese ethnic tonifying
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Untargeted metabolomic and molecular network approaches to reveal tomato root secondary metabolites Phytochem. Anal. (IF 2.772) Pub Date : 2020-11-22 Souhila Messaili; Yanyan Qu; Laëtitia Fougère; Cyril Colas; Nicolas Desneux; Anne‐Violette Lavoir; Emilie Destandau; Thomas Michel
The tomato plant, Solanum lycopersicum L. (Solanaceae), is one of the most widely consumed vegetables in the world and plays an important role in human diet. Tomato cultivars are hosts for diverse types of pests, implying diverse chemical defence strategies. Glycoalkaloids are the main specialised metabolites produced by tomato leaves and fruits to protect against pests. However, the roots have received
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Untargeted UHPLC‐Q‐TOF‐HRMS based determination of discrimating compounds for oak species Quercus robur L. and Quercus petraea Liebl. identification Phytochem. Anal. (IF 2.772) Pub Date : 2020-11-16 Gaëlle Buche; Cyril Colas; Laëtitia Fougère; Thomas Giordanengo; Emilie Destandau
Two species of oak are dominant in French forests: pedunculate oak (Quercus robur L.) and sessile oak (Quercus petraea Liebl.). Differentiating oak species is difficult, since features such as morphological characters, geographical origin and grain are not always relevant. Even if the former is generally richer in tannin compounds while the latter is often richer in aromatic compounds, the intra‐species
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Combination of electrochemical unit and ESI‐MS in fragmentation of flavonoids Phytochem. Anal. (IF 2.772) Pub Date : 2020-11-16 Gulyaim N. Sagandykova; Małgorzata Szultka‐Młyńska; Justyna Walczak‐Skierska; Paweł P. Pomastowski; Bogusław Buszewski
Predictive approaches on the activity of natural compounds based on the fragmentation by instrumental techniques are important for consideration of such molecules as drug candidates and defining new structures with promising properties. Since flavonoids are well‐known antioxidants, their redox properties can be related to their pharmacological activity.
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Rapid classification and identification of chemical constituents in Epimedium koreanum Nakai by UPLC‐Q‐TOF‐MS combined with data post‐processing techniques Phytochem. Anal. (IF 2.772) Pub Date : 2020-11-09 Ning Li; Lijuan Xie; Na Yang; Guijiang Sun; Hui Liu; Chenghao Bi; Jingyi Duan; Yu Yuan; Hongxin Yu; Yanyan Xu; Yubo Li
Epimedium koreanum Nakai (EKN), is a well‐known Chinese herbal medicine for the treatment of osteoporosis, immunosuppression, tumours and cardiovascular diseases. Comprehensive component identification is essential for elucidation of its pharmacological mechanism and quality control. However, its complex chemical composition has caused certain difficulties in the analysis of this traditional Chinese
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Immunoprotective potential of Ayurvedic herb Kalmegh (Andrographis paniculata) against respiratory viral infections – LC–MS/MS and network pharmacology analysis Phytochem. Anal. (IF 2.772) Pub Date : 2020-11-09 Subhadip Banerjee; Amit Kar; Pulok K. Mukherjee; Pallab K. Haldar; Nanaocha Sharma; Chandra Kant Katiyar
Immunity boosting has emerged as a global strategy to fight the SARS‐CoV‐2 pandemic situation. In India, AYUSH systems of medicine have been promoted as an immune‐protection strategy. Andrographis paniculata (Burm. F) Nees (AP) mentioned in Ayurveda has been widely used for treating sore throat, flu, and upper respiratory tract infections which may provide possible novel therapeutic approaches, exclusively
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Efficiency and selectivity of ionic liquids in microwave‐assisted extraction of major lichen phenolic compounds: a scalable process with recycling of ionic liquids Phytochem. Anal. (IF 2.772) Pub Date : 2020-11-04 Sarah Komaty; Aurélie Sauvager; Jean‐Pierre Bazureau; Sophie Tomasi; Ludovic Paquin
Pseudevernia furfuracea, a lichen used classically for cosmetic applications, contains interesting metabolites possessing antimicrobial and anti‐inflammatory or antioxidant properties.
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NMR‐based screening for natural product subfraction to precisely identify ligand of target protein Phytochem. Anal. (IF 2.772) Pub Date : 2020-11-02 Haipeng Jiang; Yang Liu; Jian Guo
The inherent diversity of natural product extracts has not only made their value for biological activity attractive, but has also presented significant challenges for separation and detection techniques to enable rapid characterisation of the biologically active component present in the complicated mixture.
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A green and sustainable method for monitoring the chemical composition of soybean: an alternative for quality control Phytochem. Anal. (IF 2.772) Pub Date : 2020-10-29 Maiara S. Borges; Ana C. Zanatta; Otávio A. Souza; João H. Pelissari; Júlio G.S. Camargo; Renato L. Carneiro; Cristiano S. Funari; Vanderlan S. Bolzani; Daniel Rinaldo
Soybean is one of the most important crops in the world, an important source of isoflavones, and used to treat various chronic diseases. High‐performance liquid chromatography (HPLC), associated with multivariate experiments and green solvents, is increasingly used to develop comprehensive elution methods for quality control of plants and derivatives.
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Efficient purification of the diarylheptanoid oregonin from red alder (Alnus rubra) leaves and bark combining aqueous extraction, spray drying and flash‐chromatography Phytochem. Anal. (IF 2.772) Pub Date : 2020-10-22 Carmen S. Lea; Chakravarthi Simhadri; Stephen G. Bradbury; Jeremy E. Wulff; C. Peter Constabel
The diarylheptanoid xyloside oregonin ((5S)‐1,7‐bis(3,4‐dihydroxyphenyl)‐5‐(β‐d‐xylopyranosyloxy)‐heptan‐3‐one) has significant medicinal potential and is found at high concentration in leaves and bark of red alder (Alnus rubra).
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HR‐1H NMR spectroscopy and multivariate statistical analysis to determine the composition of herbal mixtures for infusions Phytochem. Anal. (IF 2.772) Pub Date : 2020-10-14 Lucia Marchetti; Maria Cecilia Rossi; Federica Pellati; Stefania Benvenuti; Davide Bertelli
The ever‐growing diffusion and consumption of herbal teas, due to their sensory attributes and well‐known health benefits exposes them to the real risk of adulteration, especially in the case of commercial mixtures already minced for infusion. Therefore, novel and suitable tools for the control of these valuable products are increasingly required.
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Structural characterisation and screening of triterpene saponins in the bark of Ilex rotunda using high‐performance liquid chromatography coupled to electrospray ionisation and quadrupole time‐of‐flight mass spectrometry Phytochem. Anal. (IF 2.772) Pub Date : 2020-10-11 Yun Ling; Qing Zhang
The bark of Ilex rotunda (BIr) has been used as a traditional Chinese medicine for a long time in China. Triterpene saponins (TSs) were considered to be the major bioactive ingredients and possessed antiplatelet aggregation activity. Identification of TSs in BIr is a necessary step to understand the biological properties.
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Cover Image Phytochem. Anal. (IF 2.772) Pub Date : 2020-10-11 Marsha Sintara; Yifei Wang; Lin Li; Haiyan Liu; David G. Cunningham; Ronald R. Prior; Pei Chen; Tony Chang; Xianli Wu
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Issue Information Phytochem. Anal. (IF 2.772) Pub Date : 2020-10-11
No abstract is available for this article.
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Profiling of phenolic compounds in desiccation‐tolerant and non‐desiccation‐tolerant Linderniaceae Phytochem. Anal. (IF 2.772) Pub Date : 2020-10-08 Maike Passon; Fabian Weber; Niklas Udo Jung; Dorothea Bartels
Craterostigma plantagineum and Lindernia brevidens are resurrection plants, so these plants can tolerate desiccation of their vegetative tissues. Different components and mechanisms contribute to desiccation tolerance and secondary plant metabolites, like phenolic compounds, may play a role during these processes.
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Patterns and compound specific stable carbon isotope analysis (δ13C) of capsaicinoids in Cayenne chilli fruits of different ripening stages Phytochem. Anal. (IF 2.772) Pub Date : 2020-10-08 Stephanie Krauß; Laura Becker; Walter Vetter
Capsaicinoids are alkaloids of high pungency which are exclusively formed by fruits of the genus Capsicum. Capsaicinoid content and composition of Capsicum fruits are influenced by ripening.
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A monoclonal antibody‐based indirect competitive enzyme‐linked immunosorbent assay to quantify swertiamarin and related compounds in Swertia japonica Makino Phytochem. Anal. (IF 2.772) Pub Date : 2020-10-05 Poomraphie Nuntawong; Taiki Horikawa; Akihiro Ochi; Shinji Wada; Yumi Tsuneura; Hiroyuki Tanaka; Seiichi Sakamoto; Satoshi Morimoto
Swertia japonica Makino (S. japonica) has a long history of use as a folk medicine, and it is one of the three essential Japanese folk medicines. S.japonica has been reported to have various biological activities. The biologically active secoiridoid glycoside swertiamarin (SM) has been isolated from S. japonica. The efficacy of this plant is attributed to SM and related secoiridoid glycosides. To control
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Immunochromatographic assay for the detection of kwakhurin and its application for the identification of Pueraria candollei var. mirifica (Airy Shaw & Suvat.) Niyomdham Phytochem. Anal. (IF 2.772) Pub Date : 2020-10-05 Suppalak Phaisan; Gorawit Yusakul; Poomraphie Nuntawong; Seiichi Sakamoto; Waraporn Putalun; Satoshi Morimoto; Hiroyuki Tanaka
The plant Pueraria candollei var. mirifica (Airy Shaw & Suvat.) Niyomdham (PM), known by its common Thai name as white Kwao Krua, is sometimes misidentified because it presents similar botanical characteristics to those of Butea superba (red Kwao Krua). The phytochemicals in PM are phytoestrogens in the class of isoflavonoids, but Butea superba contains flavonoids that exhibit androgenic and antiestrogen
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Globoidnan A, rabdosiin and globoidnan B as new phenolic markers in European‐sourced comfrey (Symphytum officinale L.) root samples Phytochem. Anal. (IF 2.772) Pub Date : 2020-10-05 Adriana Trifan; Evelyn Wolfram; Nils Esslinger; Andreas Grubelnik; Krystyna Skalicka‐Woźniak; Mirjana Minceva; Simon Vlad Luca
Symphytum officinale L. (comfrey, Boraginaceae) is a cultivated or spontaneously growing medicinal plant that is traditionally used for the treatment of bone fractures, hematomas, muscle pains and joint pains. A wide range of topical preparations and dried roots for ex tempore applications are marketed in European drug stores or pharmacies.
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Ultrasound‐microwave‐assisted extraction of polyphenolic compounds from Mexican “Ataulfo” mango peels: Antioxidant potential and identification by HPLC/ESI/MS Phytochem. Anal. (IF 2.772) Pub Date : 2020-10-01 Anahi Ordoñez‐Torres; Cristian Torres‐León; Ayerim Hernández‐Almanza; Tirso Flores‐Guía; Diana Luque‐Contreras; Cristóbal N. Aguilar; Juan Ascacio‐Valdés
Mango is used in traditional medicine in many countries. However, the processing by‐products are not currently used and generate large pollution problems and high handling costs.
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Application of choline chloride deep eutectic solvents and high-speed counter-current chromatography to the extraction and purification of flavonoids from the thorns of Gleditsia sinensis Lam. Phytochem. Anal. (IF 2.772) Pub Date : 2020-09-17 Jinqian Yu,Lei Zhao,Xiaowei Sun,Chenglong Sun,Xiao Wang
Flavonoids are the most important and effective constituents in the thorns of Gleditsia sinensis Lam., which have been known to show antimicrobial, antiviral, anticancer, and anticoagulant activities. However, efficient extraction and separation methods for these flavonoids are not currently established.
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Simultaneous determination of multiple active 2-(2-phenylethyl)chromone analogues in agarwood by HPLC, QAMS, and UPLC-MS. Phytochem. Anal. (IF 2.772) Pub Date : 2020-09-16 Mei Gao,Xiaomin Han,Junqing Huang,Ying Sun,Yangyang Liu,Hongjiang Chen,Yue Jin,Yun Yang,Zhihui Gao,Yanhong Xu,Zheng Zhang,Chunnian He
Chromones are the major constituents of agarwood and are considered to be directly related to its quality. Agarotetrol, a chromone derivative, is a Chinese Pharmacopoeia content detection index. However, comprehensive high‐performance liquid chromatography (HPLC), quantitative analysis of multiple components by a single marker (QAMS), and ultra‐performance liquid chromatography mass spectrometry (UPLC‐MS)
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Quantification by LC-MS/MS of astragaloside IV and isoflavones in Astragali radix can be more accurate by using standard addition. Phytochem. Anal. (IF 2.772) Pub Date : 2020-09-14 Bijay Kafle,Jan Baak,Cato Brede
Astragali radix (AR), the root of Astragalus, is an important medical herb widely used in traditional Chinese medicine. Bioactive components include isoflavones and a unique class of triterpenoid saponins (named astragalosides).
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Electrospray ionisation mass spectrometric behaviour of flavonoid 5-O-glucosides and their positional isomers detected in the extracts from the bark of Prunus cerasus L. and Prunus avium L. Phytochem. Anal. (IF 2.772) Pub Date : 2020-09-14 Monika Beszterda,Rafał Frański
Literature data concerning the electrospray ionisation mass spectrometry (ESI‐MS) behaviour of flavonoid 5‐O‐glycosides are poor and sometimes disputable. Therefore, we decided to analyse the compounds of this kind present in the bark of Prunus cerasus and Prunus avium by using high‐performance liquid chromatography HPLC/ESI‐MS.
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Quantitative determination of isoflavonoids in Ononis species by UPLC-UV-DAD. Phytochem. Anal. (IF 2.772) Pub Date : 2020-09-14 Nóra Gampe,Erzsébet Nagy,László Kursinszki,Szabolcs Béni
The root of the Ononis species has been used internally and externally in ethnomedicine for centuries and contains biologically valuable isoflavonoid compounds. Therefore, it is important to obtain quantitative information about the isoflavonoid profile of these plants.
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Brazilian southeast brown propolis: gas chromatography method development for its volatile oil analysis, its antimicrobial and leishmanicidal activities evaluation. Phytochem. Anal. (IF 2.772) Pub Date : 2020-09-09 Victor Pena Ribeiro,Caroline Arruda,Jennyfer Andrea Aldana Mejía,Ana Carolina Bolela Bovo Candido,Raquel Alves Dos Santos,Lizandra Guidi Magalhães,Jairo Kenupp Bastos
Propolis is widely used in folk medicine, and many factors can affect its chemical composition, including abiotic factors that can influence plants and bees. Therefore, analytical methods are powerful techniques in the quality control of such products.
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Efficient extraction and purification of benzo[c]phenanthridine alkaloids from Macleaya cordata (Willd) R. Br. by combination of ultrahigh pressure extraction and pH-zone-refining counter-current chromatography with anti-breast cancer activity in vitro. Phytochem. Anal. (IF 2.772) Pub Date : 2020-09-08 Iftikhar Ali,Jingchao Li,Li Cui,Hongwei Zhao,Qiuxia He,Daijie Wang
Macleaya cordata (Willd) R. Br. (Papaveraceae family) is a well‐known traditional Chinese medicine used to treat muscle pain, inflamed wounds, and bee bites. Benzo[c]phenanthridine alkaloids are the main active ingredients in M. cordata. In this work, sanguinarine and chelerythrine were efficiently extracted and purified by ultrahigh‐pressure extraction (UHPE) technique and pH‐zone‐refining counter‐current
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Extraction of naturally occurring cannabinoids: an update. Phytochem. Anal. (IF 2.772) Pub Date : 2020-09-07 Lutfun Nahar,Shaikh Jamal Uddin,Md Ashraful Alam,Satyajit D Sarker
Organic molecules that interact with the cannabinoid receptors are called cannabinoids, which can be endogenous, natural or synthetic compounds. They possess similar pharmacological properties as produced by the plant, Cannabis sativa L. Before cannabinoids can be analysed, they need to be extracted from the matrices.
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Comparative pharmacokinetics of Ding-Zhi-Xiao-Wan preparation and its single herbs in rats by using a putative multiple-reaction monitoring UPLC-MS/MS method. Phytochem. Anal. (IF 2.772) Pub Date : 2020-09-07 Yufei Sun,Yang He,Shuxin Liu,Hongxue Gao,Zifeng Pi,Fengrui Song,Zhiqiang Liu,Shu Liu
The formula of Chinese medicine, Ding‐Zhi‐Xiao‐Wan (DZXW), has the distinct feature of compatibility therapy, which is attributed to the interactions of multi‐herbs. However, the quantification problem caused by the absence of pure reference standards is a bottleneck to clarify the compatibility advantages from the perspective of pharmacokinetics (PKs).
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Rapid screening and purification of potential inhibitors from Medicago sativa by ultrafiltration-liquid chromatography combined with stepwise flow rate counter-current chromatography. Phytochem. Anal. (IF 2.772) Pub Date : 2020-09-06 Wanchao Hou,Chunming Liu,Jianli Xia,Huazhou Niu,Sainan Li
Medicago sativa contains flavonoids, saponins, coumarins, sterols, monoterpenes, and organic acids, with flavonoids being the main active constituents. Flavonoids naturally contain a 2‐phenylchromone structure with antioxidant, free radical scavenging, cardiovascular, and trace estrogen‐like effects.
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Comparative LC-MS analysis of tropolone alkaloids from in vitro cultures and native sources of Gloriosa superba by Kendrick mass defect plots. Phytochem. Anal. (IF 2.772) Pub Date : 2020-09-04 Yancho Zarev,Pavlinka Popova,Kenn Foubert,Iliana Ionkova,Luc Pieters
Gloriosa superba L. is a promising antitumoural plant species as a source of colchicinoids. Ethnobotanical applications of G. superba are associated with different plant parts such as leaves, seeds, fruits, tuber and the whole plant.
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Development, validation, and application of capillary zone electrophoresis method for determination of pyrimidine glucosides in seeds of Vicia faba L. var. minor. Phytochem. Anal. (IF 2.772) Pub Date : 2020-09-02 Mariusz Kowalczyk,Justyna Krzyżanowska-Kowalczyk,Anna Stochmal
Consumption of fava beans seeds can be harmful to both humans and animals due to the presence of pyrimidine glucosides: vicine and convicine. Therefore, seeds, feed supplements, and protein extracts derived from fava beans should be monitored for the contents of pyrimidine derivatives.
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Advances in NMR techniques applicable to phytochemical analysis. Phytochem. Anal. (IF 2.772) Pub Date : 2020-08-27 Didem Şöhretoğlu
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Spectrum-effect relationship between UPLC fingerprints and anti-lung cancer effect of Panax ginseng. Phytochem. Anal. (IF 2.772) Pub Date : 2020-08-18 Xiaowei Zhou,Haiyang Liu,Mingyu Zhang,Chunyu Li,Guohui Li
Lung cancer has the highest mortality rate among the various types of cancer. Panax ginseng (C. A. Mey). is a popular anti‐cancer herbal supplement. The quality control of ginseng is crucial to ensure its clinical efficacy. This study aimed to establish new quality control methods for ginseng and to identify its main active components responsible for lung cancer treatment.