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Discovery, X-ray structure and CPP-conjugation enabled uptake of p53/MDM2 macrocyclic peptide inhibitors RSC Chem. Biol. Pub Date : 2021-08-26 Anselm F. L. Schneider, Joerg Kallen, Johannes Ottl, Patrick C. Reid, Sebastien Ripoche, Stephan Ruetz, Therese-Marie Stachyra, Samuel Hintermann, Christoph E. Dumelin, Christian P. R. Hackenberger, Andreas L. Marzinzik
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Design, synthesis and evaluation of tryptophan analogues as tool compounds to study IDO1 activity RSC Chem. Biol. Pub Date : 2021-09-13 Nicholas J. Cundy, Roseanna K. Hare, Tina Tang, Andrew G. Leach, Thomas A. Jowitt, Omar Qureshi, John Gordon, Nicholas M. Barnes, Catherine A. Brady, Emma L. Raven, Richard S. Grainger, Sam Butterworth
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A mixed chirality α-helix in a stapled bicyclic and a linear antimicrobial peptide revealed by X-ray crystallography RSC Chem. Biol. Pub Date : 2021-08-20 Stéphane Baeriswyl, Hippolyte Personne, Ivan Di Bonaventura, Thilo Köhler, Christian van Delden, Achim Stocker, Sacha Javor, Jean-Louis Reymond
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Alkyl vs. aryl modifications: a comparative study on modular modifications of triphenylphosphonium mitochondrial vectors RSC Chem. Biol. Pub Date : 2021-08-25 How Chee Ong, João T. S. Coimbra, Germain Kwek, Maria J. Ramos, Bengang Xing, Pedro A. Fernandes, Felipe García
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Target identification of mouse stem cell probe CDy1 as ALDH2 and Abcb1b through live-cell affinity-matrix and ABC CRISPRa library RSC Chem. Biol. Pub Date : 2021-08-20 Naoki Miyamoto, Young-Hyun Go, Larissa Miasiro Ciaramicoli, Haw-Young Kwon, Heon Seok Kim, Xuezhi Bi, Young Hyun Yu, Beomsue Kim, Hyung-Ho Ha, Nam-Young Kang, Seong-Wook Yun, Jin-Soo Kim, Hyuk-Jin Cha, Young-Tae Chang
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Origin, toxicity and characteristics of two amyloid oligomer polymorphs RSC Chem. Biol. Pub Date : 2021-08-25 Chamani Niyangoda, Jeremy Barton, Nabila Bushra, Kanchana Karunarathne, Graham Strauss, Fadia Fakhre, Piyush Koria, Martin Muschol
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Macrocyclic peptides as allosteric inhibitors of nicotinamide N-methyltransferase (NNMT) RSC Chem. Biol. Pub Date : 2021-08-19 Matthijs J. van Haren, Yurui Zhang, Vito Thijssen, Ned Buijs, Yongzhi Gao, Lukasz Mateuszuk, Filip A. Fedak, Agnieszka Kij, Roberto Campagna, Davide Sartini, Monica Emanuelli, Stefan Chlopicki, Seino A. K. Jongkees, Nathaniel I. Martin
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Segmental and site-specific isotope labelling strategies for structural analysis of posttranslationally modified proteins RSC Chem. Biol. Pub Date : 2021-08-11 Dominik P. Vogl, Anne C. Conibear, Christian F. W. Becker
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Squaric acid as a new chemoselective moiety for mass spectrometry-based metabolomics analysis of amines RSC Chem. Biol. Pub Date : 2021-08-12 Weifeng Lin, Zhen Yang, Amanpreet Kaur, Annika Block, Miroslav Vujasinovic, J.-Matthias Löhr, Daniel Globisch
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Towards optimizing peptide-based inhibitors of protein–protein interactions: predictive saturation variation scanning (PreSaVS) RSC Chem. Biol. Pub Date : 2021-08-16 Kristina Hetherington, Som Dutt, Amaurys A. Ibarra, Emma E. Cawood, Fruzsina Hobor, Derek N. Woolfson, Thomas A. Edwards, Adam Nelson, Richard B. Sessions, Andrew J. Wilson
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Dual concentration-dependent effect of ascorbic acid on PAP(248–286) amyloid formation and SEVI-mediated HIV infection RSC Chem. Biol. Pub Date : 2021-08-10 Satabdee Mohapatra, Guru Krishna Kumar Viswanathan, Lukas Wettstein, Elad Arad, Ashim Paul, Vijay Kumar, Raz Jelinek, Jan Münch, Daniel Segal
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Ru(II)/BODIPY core co-encapsulated ratiometric nanotools for intracellular O2 sensing in live cancer cells RSC Chem. Biol. Pub Date : 2021-07-28 Karmel Sofia Gkika, Anna Kargaard, Christopher S. Burke, Ciaran Dolan, Andreas Heise, Tia E. Keyes
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Protein–protein interaction based substrate control in the E. coli octanoic acid transferase, LipB RSC Chem. Biol. Pub Date : 2021-07-28 Thomas G. Bartholow, Terra Sztain, Megan A. Young, Tony D. Davis, Ruben Abagyan, Michael D. Burkart
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Targeting the RNA demethylase FTO for cancer therapy RSC Chem. Biol. Pub Date : 2021-07-26 Lin-Lin Zhou, Hongjiao Xu, Yue Huang, Cai-Guang Yang
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Members of the Legionella pneumophila Sde family target tyrosine residues for phosphoribosyl-linked ubiquitination RSC Chem. Biol. Pub Date : 2021-07-29 Mengyun Zhang, Joseph M. McEwen, Nicole M. Sjoblom, Kristin M. Kotewicz, Ralph R. Isberg, Rebecca A. Scheck
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Environment and coordination of FeMo–co in the nitrogenase metallochaperone NafY RSC Chem. Biol. Pub Date : 2021-07-28 Aaron H. Phillips, Jose A. Hernandez, Lucía Payá-Tormo, Stefan Burén, Bruno Cuevas-Zuviría, Luis F. Pacios, Jeffrey G. Pelton, David E. Wemmer, Luis M. Rubio
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A cell permeable bimane-constrained PCNA-interacting peptide RSC Chem. Biol. Pub Date : 2021-07-21 Aimee J. Horsfall, Beth A. Vandborg, Zoya Kikhtyak, Denis B. Scanlon, Wayne D. Tilley, Theresa E. Hickey, John B. Bruning, Andrew D. Abell
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Targeted disruption of PKC from AKAP signaling complexes RSC Chem. Biol. Pub Date : 2021-07-19 Ameya J. Limaye, George N. Bendzunas, Eileen J. Kennedy
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Correction: Antibody recruiting molecules (ARMs): synthetic immunotherapeutics to fight cancer RSC Chem. Biol. Pub Date : 2021-07-22 Silvia Achilli, Nathalie Berthet, Olivier Renaudet
Correction for ‘Antibody recruiting molecules (ARMs): synthetic immunotherapeutics to fight cancer’ by Silvia Achilli et al., RSC Chem. Biol., 2021, 2, 713–724. DOI: 10.1039/d1cb00007a.
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Faster, better, and cheaper: harnessing microfluidics and mass spectrometry for biotechnology RSC Chem. Biol. Pub Date : 2021-07-20 Noel S. Ha, Markus de Raad, La Zhen Han, Amber Golini, Christopher J. Petzold, Trent R. Northen
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Orthogonal coiled coils enable rapid covalent labelling of two distinct membrane proteins with peptide nucleic acid barcodes RSC Chem. Biol. Pub Date : 2021-07-16 Georgina C. Gavins, Katharina Gröger, Marc Reimann, Michael D. Bartoschek, Sebastian Bultmann, Oliver Seitz
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Phosphinate esters as novel warheads for activity-based probes targeting serine proteases RSC Chem. Biol. Pub Date : 2021-07-09 Jan Pascal Kahler, Steven H. L. Verhelst
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19 F NMR viewed through two different lenses: ligand-observed and protein-observed 19F NMR applications for fragment-based drug discovery RSC Chem. Biol. Pub Date : 2021-07-12 Caroline R. Buchholz, William C. K. Pomerantz
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In vivo active organometallic-containing antimycotic agents RSC Chem. Biol. Pub Date : 2021-07-08 Riccardo Rubbiani, Tobias Weil, Noemi Tocci, Luciano Mastrobuoni, Severin Jeger, Marco Moretto, James Ng, Yan Lin, Jeannine Hess, Stefano Ferrari, Andres Kaech, Luke Young, John Spencer, Anthony L. Moore, Kevin Cariou, Giorgia Renga, Marilena Pariano, Luigina Romani, Gilles Gasser
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Entropy of stapled peptide inhibitors in free state is the major contributor to the improvement of binding affinity with the GK domain RSC Chem. Biol. Pub Date : 2021-06-25 Ilona Christy Unarta, Jianchao Xu, Yuan Shang, Carina Hey Pui Cheung, Ruichi Zhu, Xudong Chen, Siqin Cao, Peter Pak-Hang Cheung, Donald Bierer, Mingjie Zhang, Xuhui Huang, Xuechen Li
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A decade of alkyne-tag Raman imaging (ATRI): applications in biological systems RSC Chem. Biol. Pub Date : 2021-07-14 Subha Bakthavatsalam, Kosuke Dodo, Mikiko Sodeoka
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Reactive oxygen species, proinflammatory and immunosuppressive mediators induced in COVID-19: overlapping biology with cancer RSC Chem. Biol. Pub Date : 2021-06-30 Balaraman Kalyanaraman
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Untangling the interaction of α-synuclein with DNA i-motifs and hairpins by volume-sensitive single-molecule FRET spectroscopy RSC Chem. Biol. Pub Date : 2021-07-02 Sanjib K. Mukherjee, Jim-Marcel Knop, Rosario Oliva, Simone Möbitz, Roland Winter
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Correction: Antibacterial activity of a dual peptide targeting the Escherichia coli sliding clamp and the ribosome RSC Chem. Biol. Pub Date : 2021-07-06 Christophe André, Florian Veillard, Philippe Wolff, Anne-Marie Lobstein, Guillaume Compain, Clément Monsarrat, Jean-Marc Reichhart, Dominique Y. Burnouf, Gilles Guichard, Jérôme E. Wagner
Correction for ‘Antibacterial activity of a dual peptide targeting the Escherichia coli sliding clamp and the ribosome’ by Christophe André et al., RSC Chem. Biol., 2020, 1, 137–147, DOI: 10.1039/D0CB00060D.
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A self-labeling protein based on the small ultra-red fluorescent protein, smURFP RSC Chem. Biol. Pub Date : 2021-06-29 John-Hanson Machado, Richard Ting, John Y. Lin, Erik A. Rodriguez
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Measuring ROS and redox markers in plant cells RSC Chem. Biol. Pub Date : 2021-06-29 Salma Akter, Mohammad Shahneawz Khan, Edward N. Smith, Emily Flashman
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Versatile naphthalimide tetrazines for fluorogenic bioorthogonal labelling RSC Chem. Biol. Pub Date : 2021-07-05 Marcus E. Graziotto, Liam D. Adair, Amandeep Kaur, Pauline Vérité, Sarah R. Ball, Margaret Sunde, Denis Jacquemin, Elizabeth J. New
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Computational design and experimental characterization of a photo-controlled mRNA-cap guanine-N7 methyltransferase RSC Chem. Biol. Pub Date : 2021-06-29 Dennis Reichert, Helena Schepers, Julian Simke, Horst Lechner, Wolfgang Dörner, Birte Höcker, Bart Jan Ravoo, Andrea Rentmeister
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Self-cleaving ribozymes: substrate specificity and synthetic biology applications RSC Chem. Biol. Pub Date : 2021-07-02 Huan Peng, Brandon Latifi, Sabine Müller, Andrej Lupták, Irene A. Chen
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Targeting protein–protein interactions in the DNA damage response pathways for cancer chemotherapy RSC Chem. Biol. Pub Date : 2021-06-21 Kerry Silva McPherson, Dmitry M. Korzhnev
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Direct targeting of TDP-43, from small molecules to biologics: the therapeutic landscape RSC Chem. Biol. Pub Date : 2021-06-21 Liberty Francois-Moutal, David Donald Scott, May Khanna
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Wnt signaling activation: targets and therapeutic opportunities for stem cell therapy and regenerative medicine RSC Chem. Biol. Pub Date : 2021-06-01 Clémence Bonnet, Anvi Brahmbhatt, Sophie X. Deng, Jie J. Zheng
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Imaging therapeutic peptide transport across intestinal barriers RSC Chem. Biol. Pub Date : 2021-6-15 Jannik Bruun Larsen, Nayere Taebnia, Alireza Dolatshahi-Pirouz, Anne Zebitz Eriksen, Claudia Hjørringgaard, Kasper Kristensen, Nanna Wichmann Larsen, Niels Bent Larsen, Rodolphe Marie, Ann-Kathrin Mündler, Ladan Parhamifar, Andrew James Urquhart, Arjen Weller, Kim I. Mortensen, Henrik Flyvbjerg, Thomas Lars Andresen
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Lysine succinylation on non-histone chromosomal protein HMG-17 (HMGN2) regulates nucleosomal DNA accessibility by disrupting the HMGN2–nucleosome association RSC Chem. Biol. Pub Date : 2021-5-27 Yihang Jing, Gaofei Tian, Xiaoyu Qin, Zheng Liu, Xiang David Li
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Quantification and mapping of DNA modifications RSC Chem. Biol. Pub Date : 2021-5-21 Yi Dai, Bi-Feng Yuan, Yu-Qi Feng
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Elongation rate and average length of amyloid fibrils in solution using isotope-labelled small-angle neutron scattering RSC Chem. Biol. Pub Date : 2021-4-14 Ben J. Eves, James J. Doutch, Ann E. Terry, Han Yin, Martine Moulin, Michael Haertlein, V. Trevor Forsyth, Patrick Flagmeier, Tuomas P. J. Knowles, David M. Dias, Gudrun Lotze, Annela M. Seddon, Adam M. Squires
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What's all the phos about? Insights into the phosphorylation state of the RNA polymerase II C-terminal domain via mass spectrometry RSC Chem. Biol. Pub Date : 2021-6-3 Blase M. LeBlanc, R. Yvette Moreno, Edwin E. Escobar, Mukesh Kumar Venkat Ramani, Jennifer S. Brodbelt, Yan Zhang
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Deciphering the substrate recognition mechanisms of the heparan sulfate 3-O-sulfotransferase-3 RSC Chem. Biol. Pub Date : 2021-5-28 Rylee Wander, Andrea M. Kaminski, Yongmei Xu, Vijayakanth Pagadala, Juno M. Krahn, Truong Quang Pham, Jian Liu, Lars C. Pedersen
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Leucine-rich alpha-2-glycoprotein 1 (LRG1) as a novel ADC target RSC Chem. Biol. Pub Date : 2021-5-31 Faiza Javaid, Camilla Pilotti, Carlotta Camilli, David Kallenberg, Calise Bahou, Jack Blackburn, James R. Baker, John Greenwood, Stephen E. Moss, Vijay Chudasama
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Interfacing non-enzymatic catalysis with living microorganisms RSC Chem. Biol. Pub Date : 2021-6-4 Joanna C. Sadler, Jonathan A. Dennis, Nick W. Johnson, Stephen Wallace
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Evaluating the effect of ionic strength on PNA:DNA duplex formation kinetics RSC Chem. Biol. Pub Date : 2021-5-21 Colin S. Swenson, Hershel H. Lackey, Eric J. Reece, Joel M. Harris, Jennifer M. Heemstra, Eric M. Peterson
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Recent developments and applications of quantitative proteomics strategies for high-throughput biomolecular analyses in cancer research RSC Chem. Biol. Pub Date : 2021-5-19 Hannah N. Miles, Daniel G. Delafield, Lingjun Li
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Correction: In vivo modulation of ubiquitin chains by N-methylated non-proteinogenic cyclic peptides RSC Chem. Biol. Pub Date : 2021-5-11 Joseph M. Rogers, Mickal Nawatha, Betsegaw Lemma, Ganga B. Vamisetti, Ido Livneh, Uri Barash, Israel Vlodavsky, Aaron Ciechanover, David Fushman, Hiroaki Suga, Ashraf Brik
Correction for ‘In vivo modulation of ubiquitin chains by N-methylated non-proteinogenic cyclic peptides’ by Joseph M. Rogers et al., RSC Chem. Biol., 2021, 2, 513–522, DOI: 10.1039/D0CB00179A.
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Strategies to promote permeation and vectorization, and reduce cytotoxicity of metal complex luminophores for bioimaging and intracellular sensing RSC Chem. Biol. Pub Date : 2021-5-5 Lorcan Holden, Christopher S. Burke, David Cullinane, Tia E. Keyes
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Aggregation of protein therapeutics enhances their immunogenicity: causes and mitigation strategies RSC Chem. Biol. Pub Date : 2021-5-4 Mimmi L. E. Lundahl, Silvia Fogli, Paula E. Colavita, Eoin M. Scanlan
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One-pot fluorescent assay for sensitive detection of APOBEC3A activity RSC Chem. Biol. Pub Date : 2021-4-30 Bingyao Wang, Xiong Zhang, Yafen Wang, Kun Chen, Fang Wang, Xiaocheng Weng, Xiang Zhou
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Sulfur modification in natural RNA and therapeutic oligonucleotides RSC Chem. Biol. Pub Date : 2021-4-27 Ya Ying Zheng, Ying Wu, Thomas J. Begley, Jia Sheng
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Optical chemosensors for the detection of proximally phosphorylated peptides and proteins RSC Chem. Biol. Pub Date : 2021-4-21 Aaron D. Cabral, Tudor B. Radu, Elvin D. de Araujo, Patrick T. Gunning
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The two domains of human galectin-8 bind sialyl- and fucose-containing oligosaccharides in an independent manner. A 3D view by using NMR RSC Chem. Biol. Pub Date : 2021-4-12 Marcos Gómez-Redondo, Sandra Delgado, Reyes Núñez-Franco, Gonzalo Jiménez-Osés, Ana Ardá, Jesús Jiménez-Barbero, Ana Gimeno
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Synthesis and immunological effects of C14-linked 4,5-epoxymorphinan analogues as novel heroin vaccine haptens RSC Chem. Biol. Pub Date : 2021-4-19 Eugene S. Gutman, Thomas C. Irvin, J. Brian Morgan, Rodell C. Barrientos, Oscar B. Torres, Zoltan Beck, Gary R. Matyas, Arthur E. Jacobson, Kenner C. Rice
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Glycan–protein interactions determine kinetics of N-glycan remodeling RSC Chem. Biol. Pub Date : 2021-4-16 Corina Mathew, R. Gregor Weiß, Christoph Giese, Chia-wei Lin, Marie-Estelle Losfeld, Rudi Glockshuber, Sereina Riniker, Markus Aebi
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Correction: Bypassing the requirement for aminoacyl-tRNA by a cyclodipeptide synthase enzyme RSC Chem. Biol. Pub Date : 2021-4-14 Christopher J. Harding, Emmajay Sutherland, Jane G. Hanna, Douglas R. Houston, Clarissa M. Czekster
Correction for ‘Bypassing the requirement for aminoacyl-tRNA by a cyclodipeptide synthase enzyme’ by Christopher J. Harding et al., RSC Chem. Biol., 2021, 2, 230–240, DOI: 10.1039/D0CB00142B.
更新日期：2021-09-16
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