In this study, phenolic composition and in vitro biological activities of ethyl acetate (EAE) and methanol (ME) extracts obtained from the aerial parts of endemic Tanacetum erzincanense were investigated. Total phenolic and flavonoid content of the extracts were determined by Folin‐Ciocalteu and Aluminium Chloride colorimetric methods, respectively. Antioxidant capacity of the extracts was evaluated

The present study aimed to determine the chemical composition and biological activity of the essential oil obtained from Phyllogoniun viride Brid.(Phyllogoniaceae, Bryophyta), whose samples were collected in southern Brazil. The cytotoxic activity of the essential oil of P. viride in breast and colorectal tumor cells (MCF‐7 and HCT‐116) was evaluated, as well as the cytotoxic potential of this oil

The present article reports results of analysis of carboxylic acids in leaves of Iris species from Ukraine using a gas chromatography (GC) method with mass spectrometric (MS) detection (GC/MS). Carboxylic acids play significant roles in contemporary society as evidenced by multiple applications in fields of medicine, agriculture, pharmacy, food, and other industries. Study of natural plant products

Thymus is one of the most important genera of the Lamiaceae family. This work was performed to assess inter and intra species variation, which is an indispensable prerequisite for the selection and the exploitation of the germplasm, using yield, secondary metabolites, and ploidy level criteria. Nineteen Iranian populations belonging to 11 Thymus species which includes T. vulgaris were used in this

Acylpeptide hydrolase is a serine protease which, together with prolyl oligopeptidase, dipeptidyl peptidase IV and oligopeptidase B belongs to the prolyl oligopeptidase family. Its primary function is associated with the removal of N‐acetylated amino acid residues from proteins and peptides. Although the N‐acylation occurs in 50‐90% of eukaryotic proteins, the precise functions of this modification

This study was undertaken to determine the influence of salicylic acid (SA) on the bioactive phytochemicals and antioxidant capacity of wheatgrass extract in the organic growing medium. Wheatgrass was cultivated in SA‐enriched organic growing medium, obtained from acetylsalicylic acid (aspirin), of various concentrations (0 [control], 0.25, 0.50, 1.00, and 2.00 mM) in a plant growth chamber by controlling

Fractionation of the ethanol extract of a marine fungus, Arthrinium sp., afforded a new pyridone alkaloid (arthpyrone L, 1 ), the structure with absolute configuration of which was established by comprehensive spectroscopic analyses. In vitro cell viability assays revealed that compound 1 showed antiproliferative effects toward human A549 (lung), MG63, U2OS (bone), MCF‐7 and MDA‐MB‐231 (breast) cancer

This review focuses on four new product categories of food supplements: pre‐workout, fat burner/thermogenic, brain/cognitive booster, and hormone/testosterone booster. Many food supplements have been shown to be contaminated with unauthorized substances. In some cases, the ingredients in the new categories of dietary supplements were medicinal products or new synthetic compounds added without performing

The chemical profile and phytotoxic action of Hibiscus trionum essential oil (EO) was studied. In total 17 compounds were identified via GC/MS, representing 94.18% of the entire oil, with phytol (40.37%) being the dominant constituent. Bioassay revealed that the EO inhibited root elongation of Medicago sativa and Amaranthus retroflexus by 32.66% and 61.86% at 5 mg/mL, respectively; meanwhile, the major

Genistein (GS) exhibits various biological activities, but its clinical application is limited because of the low bioavailability. In this study, a GS‐adenine pharmaceutical complex was prepared through solvent evaporation to improve the bioavailability of GS, and a molecular model of a two‐component supramolecular pharmacological transport mechanism was established. The structure of GS‐adenine was

Glucokinase (GLK) and Hexokinase (HK) have been characterized as essential targets in Trypanosoma cruzi ( Tc )‐mediated infection. A recent study reported the propensity of the concomitant inhibition of Tc GLK and Tc HK by compounds GLK2‐003 and GLK2‐004, thereby presenting an efficient approach in Chagas disease treatment. We investigated this possibility using atomic and molecular scaling methods

Paeonia cultivars are famous ornamental plants, and some of them are also traditional Chinese medicinal resources. Intersubgeneric hybrids of Paeonia (IHPs) are formed by the hybridization of herbaceous peony ( Paeonia lactiflora ) and tree peony ( Paeonia × suffruticosa or lutea hybrid tree peony). The phenotypic characteristics of IHPs are similar to those of herbaceous peony, and their root systems are large

Five new diterpenoids, named euphorfischerins A–E, were isolated from the roots of Euphorbia fischeriana. Their chemical structures and absolute configurations were determined by interpretation of NMR, HR‐ESI‐MS, ECD and X‐ray diffraction data. Euphorfischerin A showed cytotoxicity against the human cancer cell lines HeLa, H460 and Namalwa with IC50 values of 4.6, 11.5 and 16.4 μM, respectively, while

Cosmeceutical field, which merges cosmetics and pharmaceuticals , is nowadays a highly investigated research area, because a scientific demonstration of the claimed bioactivity of new cosmeceutical ingredients is increasingly requested. In fact, an aspect differentiating traditional cosmetics from cosmeceuticals is the identification and characterization of the active ingredients and demonstrating