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Macromolecular crowding has opposite effects on two critical sub‐steps of transcription initiation FEBS Lett. (IF 3.5) Pub Date : 2024-03-14 Pratip Mukherjee, Abhishek Mazumder
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Redox imbalance and metabolic defects in the context of Alzheimer disease FEBS Lett. (IF 3.5) Pub Date : 2024-03-13 Fabio Di Domenico, Chiara Lanzillotta, Marzia Perluigi
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Phosphorylation of TG‐interacting factor 1 at carboxyl‐terminal sites in response to insulin regulates adipocyte differentiation FEBS Lett. (IF 3.5) Pub Date : 2024-03-13 Yu‐Hao Chang, Yu‐Hua Tseng, Ju‐Ming Wang, Yau‐Sheng Tsai, Xin‐Lei Liu, Huei‐Sheng Huang
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Cdc73 is a major regulator of apoptosis‐inducing factor 1 expression in Saccharomyces cerevisiae via H3K36 methylation FEBS Lett. (IF 3.5) Pub Date : 2024-03-12 Nitu Saha, Santoshi Acharjee, Raghuvir Singh Tomar
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How enzyme‐centered approaches are advancing research on cyclic oligo‐nucleotides FEBS Lett. (IF 3.5) Pub Date : 2024-03-08 Simon J. Wenzl, Carina C. de Oliveira Mann
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TERRA and the alternative lengthening of telomeres: a dangerous affair FEBS Lett. (IF 3.5) Pub Date : 2024-03-06 Claus M. Azzalin
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Uncovering domain motif interactions using high‐throughput protein–protein interaction detection methods FEBS Lett. (IF 3.5) Pub Date : 2024-03-05 Sobia Idrees, Keshav Raj Paudel, Tayyaba Sadaf, Philip M. Hansbro
Protein–protein interactions (PPIs) are often mediated by short linear motifs (SLiMs) in one protein and domain in another, known as domain–motif interactions (DMIs). During the past decade, SLiMs have been studied to find their role in cellular functions such as post‐translational modifications, regulatory processes, protein scaffolding, cell cycle progression, cell adhesion, cell signalling and substrate
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Recruitment of ubiquitin E2 enzymes is determined jointly by the U‐box domains and substrates of E3 ligases FEBS Lett. (IF 3.5) Pub Date : 2024-03-05 Bo Jin, Bei Li, Junyao Qu, Yiheng Sun, Mengran Wang, Changjiang Yang, Yuchen Fan, Yanan Wang, Peng Xu, Haiying Sun, Bo Jiang, Bo Zhao
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A life‐time of hematopoietic cell function: ascent, stability, and decline FEBS Lett. (IF 3.5) Pub Date : 2024-03-05 Anna Popravko, Lorna Mackintosh, Elaine Dzierzak
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Assessment of machine‐learning predictions for the Mediator complex subunit MED25 ACID domain interactions with transactivation domains FEBS Lett. (IF 3.5) Pub Date : 2024-03-04 Didier Monté, Zoé Lens, Frédérique Dewitte, Vincent Villeret, Alexis Verger
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The extremophilic Andean isolate Acinetobacter sp. Ver3 expresses two ferredoxin‐NADP+ reductase isoforms with different catalytic properties FEBS Lett. (IF 3.5) Pub Date : 2024-03-04 Alejandro Palavecino, Mariana Gabriela Sartorio, Néstor Carrillo, Néstor Cortez, Ana Bortolotti
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Crystal structure and solution scattering of Geobacillus stearothermophilus S9 peptidase reveal structural adaptations for carboxypeptidase activity FEBS Lett. (IF 3.5) Pub Date : 2024-03-01 Khileshwari Chandravanshi, Rahul Singh, Gauri N. Bhange, Ashwani Kumar, Pooja Yadav, Amit Kumar, Ravindra D. Makde
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How CBX proteins regulate normal and leukemic blood cells FEBS Lett. (IF 3.5) Pub Date : 2024-03-01 Anne P. de Groot, Gerald de Haan
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Resveratrol and its metabolites elicit neuroprotection via high‐affinity binding to the laminin receptor at low nanomolar concentrations FEBS Lett. (IF 3.5) Pub Date : 2024-02-28 Rayudu Gopalakrishna, Jennifer Aguilar, Andrew Oh, Emily Lee, Lucas Hou, Tammy Lee, Eric Xu, James Nguyen, William J. Mack
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Interlinked bi‐stable switches govern the cell fate commitment of embryonic stem cells FEBS Lett. (IF 3.5) Pub Date : 2024-02-27 Amitava Giri, Sandip Kar
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Probing the legitimate initiation of RNA synthesis by Qβ replicase with oligonucleotide primers FEBS Lett. (IF 3.5) Pub Date : 2024-02-26 Kirill V. Lobodin, Helena V. Chetverina, Alexander B. Chetverin
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Cryo-EM structure of the inactive ribosome complex accumulated in chick embryo cells in cold-stress conditions FEBS Lett. (IF 3.5) Pub Date : 2024-02-23 Liliia Nurullina, Salvatore Terrosu, Alexander G. Myasnikov, Lasse Bohl Jenner, Marat Yusupov
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Protein sorting upon exit from the endoplasmic reticulum dominates Golgi biogenesis in budding yeast FEBS Lett. (IF 3.5) Pub Date : 2024-02-23 Saku Sasaki, Philipp Schlarmann, Kazuki Hanaoka, Hinako Nishii, Hisao Moriya, Manuel Muñiz, Kouichi Funato
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Deletion of the transcription factors Hsf1, Msn2 and Msn4 in yeast uncovers transcriptional reprogramming in response to proteotoxic stress FEBS Lett. (IF 3.5) Pub Date : 2024-02-16 Moritz Mühlhofer, Felix Offensperger, Sarah Reschke, Georg Wallmann, Gergely Csaba, Evi Berchtold, Maximilian Riedl, Helmut Blum, Martin Haslbeck, Ralf Zimmer, Johannes Buchner
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Strigolactone biosynthesis in rice can occur via a 9-cis-3-OH-10′-apo-β-carotenal intermediate FEBS Lett. (IF 3.5) Pub Date : 2024-02-19 Jian You Wang, Guan-Ting Erica Chen, Aparna Balakrishna, Muhammad Jamil, Lamis Berqdar, Salim Al-Babili
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The positive allosteric modulator BPAM344 and L‐glutamate introduce an active‐like structure of the ligand‐binding domain of GluK2 FEBS Lett. (IF 3.5) Pub Date : 2024-02-19 Yasmin Bay, Mie Egeberg Jeppesen, Karla Frydenvang, Pierre Francotte, Bernard Pirotte, Darryl S. Pickering, Anders Skov Kristensen, Jette Sandholm Kastrup
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Identification and characterization of nuclear localization signals in the circumsporozoite protein of Plasmodium falciparum FEBS Lett. (IF 3.5) Pub Date : 2024-02-19 Akshaykumar Nanaji Shrikondawar, Kiranmai Chennoju, Debasish Kumar Ghosh, Akash Ranjan
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CIDE proteins and their regulatory mechanisms in lipid droplet fusion and growth FEBS Lett. (IF 3.5) Pub Date : 2024-02-14 Li Xu, Lizhen Li, Lingzhi Wu, Peng Li, Feng-Jung Chen
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A unifying mechanism for seipin-mediated lipid droplet formation FEBS Lett. (IF 3.5) Pub Date : 2024-02-13 Yoel A. Klug, Joana V. Ferreira, Pedro Carvalho
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The three-dimensional structure of the Vint domain from Tetrahymena thermophila suggests a ligand-regulated cleavage mechanism by the HINT fold FEBS Lett. (IF 3.5) Pub Date : 2024-02-13 Hideo Iwaï, Hannes M. Beyer, Julia E. M. Johansson, Mi Li, Alexander Wlodawer
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Lipid sensing nuclear receptors involved in the pathogenesis of fatty liver disease FEBS Lett. (IF 3.5) Pub Date : 2024-02-13 Marion Schweiger, Maria Nieves Arredondo-Lasso, Marika E. Friano, Manuel Gil-Lozano, Stephan Herzig, Nina Henriette Uhlenhaut
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Cell competition: emerging signaling and unsolved questions FEBS Lett. (IF 3.5) Pub Date : 2024-02-13 Rina Nagata, Tatsushi Igaki
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Correction to “Gly56 in the synthetic site of isoleucyl-tRNA synthetase confers specificity and maintains communication with the editing site” FEBS Lett. (IF 3.5) Pub Date : 2024-02-13
Morana Dulic, Nina Krpan, Ita Gruic-Sovulj Gly56 in the synthetic site of isoleucyl-tRNA synthetase confers specificity and maintains communication with the editing site. FEBS Letters, 2023 December; 597; 3114–3124. DOI: 10.1002/1873-3468.14780 Figure 3 was incorrect. It has two parts, A and B, and the appropriate x-axis should not be the same. In Fig. 3A, x-axis should be t/s, while in 3B, it should
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A two-step mechanism for the binding of the HIV-1 MPER epitope by the 10E8 antibody onto biosensor-supported lipid bilayers FEBS Lett. (IF 3.5) Pub Date : 2024-02-09 Miguel García-Porras, Johana Torralba, Sara Insausti, Javier Valle, David Andreu, Beatriz Apellániz, José L. Nieva
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Lipid droplets provide metabolic flexibility for cancer progression FEBS Lett. (IF 3.5) Pub Date : 2024-02-07 Rémi Safi, Pablo Menéndez, Albert Pol
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Osmotic stress induces the formation of migrasome-like vesicles FEBS Lett. (IF 3.5) Pub Date : 2024-02-09 Koki Yoshikawa, Shogo Saito, Tetsuya Kadonosono, Masayoshi Tanaka, Mina Okochi
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The lipid-binding D4 domain of perfringolysin O facilitates the active loading of exogenous cargo into extracellular vesicles FEBS Lett. (IF 3.5) Pub Date : 2024-02-09 Abayomi Emmanuel Opadele, Soichiro Nishioka, Ping-Hsiu Wu, Quynh-Thu Le, Hiroki Shirato, Jin-Min Nam, Yasuhito Onodera
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Remodelling of mitochondrial function by import of specific lipids at multiple membrane-contact sites FEBS Lett. (IF 3.5) Pub Date : 2024-02-04 Aksel J. Saukko-Paavola, Robin W. Klemm
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MATR3 pathogenic variants differentially impair its cryptic splicing repression function FEBS Lett. (IF 3.5) Pub Date : 2024-02-06 Mashiat Khan, Xiao Xiao Lily Chen, Michelle Dias, Jhune Rizsan Santos, Sukhleen Kour, Justin You, Rebekah van Bruggen, Mohieldin M. M. Youssef, Ying-Wooi Wan, Zhandong Liu, Jill A. Rosenfeld, Qiumin Tan, Udai Bhan Pandey, Hari Krishna Yalamanchili, Jeehye Park
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The prefoldin-like protein AtURI exhibits characteristics of intrinsically disordered proteins FEBS Lett. (IF 3.5) Pub Date : 2024-02-01 Yaiza Gómez-Mínguez, Alberto Palacios-Abella, Cecilia Costigliolo-Rojas, Mariana Barber, Laura Hernández-Villa, Cristina Úrbez, David Alabadí
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Mdm2-mediated ubiquitination of PKCβII is responsible for insulin-induced heterologous desensitization of dopamine D3 receptor FEBS Lett. (IF 3.5) Pub Date : 2024-02-01 Xingyue Zeng, ChengYan Wu, Yongkai Cao, Huijun Li, Xiaohan Zhang
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Mitochondrial dysfunction in NPC1-deficiency is not rescued by drugs targeting the glucosylceramidase GBA2 and the cholesterol-binding proteins TSPO and StARD1 FEBS Lett. (IF 3.5) Pub Date : 2024-02-01 Simon Wheeler, Meenakshi Bhardwaj, Victor Kenyon, Maria J. Ferraz, Johannes M. F. G. Aerts, Dan J. Sillence
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Lipid droplets and fatty acid-induced lipotoxicity: in a nutshell FEBS Lett. (IF 3.5) Pub Date : 2024-01-28 Eseiwi Obaseki, Daniel Adebayo, Sumit Bandyopadhyay, Hanaa Hariri
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Dietary (poly)phenols as modulators of the biophysical properties in endothelial cell membranes: its impact on nitric oxide bioavailability in hypertension FEBS Lett. (IF 3.5) Pub Date : 2024-01-28 Ana Reis, Barbara S. Rocha, João Laranjinha, Victor de Freitas
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Autophagy-dependent alternative splicing of ribosomal protein S24 produces a more stable isoform that aids in hypoxic cell survival FEBS Lett. (IF 3.5) Pub Date : 2024-01-28 Jenna Kerry, Erin J. Specker, Morgan Mizzoni, Andrea Brumwell, Leslie Fell, Jenna Goodbrand, Michael N. Rosen, James Uniacke
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Apolipoprotein E isoforms and their Cys-thiol modifications impact LRP1-mediated metabolism of triglyceride-rich lipoproteins FEBS Lett. (IF 3.5) Pub Date : 2024-01-27 Hiroto Matsuura, Shogo Akahane, Takahiro Kaido, Tomu Kamijo, Kenta Sakamoto, Kazuyoshi Yamauchi
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Functional interplay of lipid droplets and mitochondria FEBS Lett. (IF 3.5) Pub Date : 2024-01-24 Ludovic Enkler, Anne Spang
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Uncovering mechanisms of interorganelle lipid transport by enzymatic mass tagging FEBS Lett. (IF 3.5) Pub Date : 2024-01-24 Arun T. John Peter, Benoit Kornmann
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Advances in multimodal mass spectrometry for single-cell analysis and imaging enhancement FEBS Lett. (IF 3.5) Pub Date : 2024-01-19 Seth W. Croslow, Timothy J. Trinklein, Jonathan V. Sweedler
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Mapping secondary substrate-binding sites on the GH11 xylanase from Bacillus subtilis FEBS Lett. (IF 3.5) Pub Date : 2024-01-22 Gustavo Avelar Molina, Luis Felipe Santos Mendes, Carlos Alessandro Fuzo, Antonio José Costa-Filho, Richard John Ward
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Structural basis for substrate and antibiotic recognition by Helicobacter pylori isoleucyl-tRNA synthetase FEBS Lett. (IF 3.5) Pub Date : 2024-01-21 Xiaobao Chen, Yu Guo, Jiawen Shi, Yilun Wang, Xinyi Guo, Guihua Wu, Sheng Li, Tianlong Zhang
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Insights into the pathogenesis of primary hyperoxaluria type I from the structural dynamics of alanine:glyoxylate aminotransferase variants FEBS Lett. (IF 3.5) Pub Date : 2024-01-19 Pavla Vankova, Juan Luis Pacheco-Garcia, Dmitry S. Loginov, Atanasio Gómez-Mulas, Alan Kádek, José Manuel Martín-Garcia, Eduardo Salido, Petr Man, Angel L. Pey
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From synaptic dysfunction to atypical emotional processing in autism FEBS Lett. (IF 3.5) Pub Date : 2024-01-17 Sara L. Reis, Patricia Monteiro
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Autophagy—from yeast to humans: Thirty years of molecular autophagy FEBS Lett. (IF 3.5) Pub Date : 2024-01-11 Tassula Proikas-Cezanne, Michael Thumm
The goals and scope of many prestigious journals today encourage authors to submit articles in areas of great biological importance, and autophagy is often and explicitly mentioned here. This has not always been the case. For a long time, the question of how excess or damaged intracellular material is transported to lysosomes/vacuoles for degradation and reuse only interested a few experts studying
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Structural determinants of phosphorylation-dependent nuclear transport of HCMV DNA polymerase processivity factor UL44 FEBS Lett. (IF 3.5) Pub Date : 2023-12-29 Emily M. Cross, Oriano Marin, Daryl Ariawan, David Aragão, Giorgio Cozza, Enzo Di Iorio, Jade K. Forwood, Gualtiero Alvisi
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Membranes that make fat: roles of membrane lipids as acyl donors for triglyceride synthesis and organelle function FEBS Lett. (IF 3.5) Pub Date : 2023-12-23 Antonio D. Barbosa, Symeon Siniossoglou
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Molecular mechanisms of perilipin protein function in lipid droplet metabolism FEBS Lett. (IF 3.5) Pub Date : 2023-12-23 Elena Griseti, Abdoul Akim Bello, Eric Bieth, Bayane Sabbagh, Jason S. Iacovoni, Joëlle Bigay, Henrik Laurell, Alenka Čopič
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Redox and metabolic reprogramming in breast cancer and cancer-associated adipose tissue FEBS Lett. (IF 3.5) Pub Date : 2023-12-23 Tamara Zakic, Vanja Pekovic-Vaughan, Aleksandra Cvoro, Aleksandra Korac, Aleksandra Jankovic, Bato Korac
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A-kinase anchoring proteins are enriched in the central pair microtubules of motile cilia in Chlamydomonas reinhardtii FEBS Lett. (IF 3.5) Pub Date : 2023-12-23 Venkatramanan G. Rao, Amruta A. Shendge, Percival P. D'Gama, Elvis A. F. Martis, Shraddha Mehta, Evans C. Coutinho, Jacinta S. D'Souza