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mTOR-mediated differentiation and maintenance of suppressive T cells at the center stage of IPEX treatment Immunol. Res. (IF 4.4) Pub Date : 2024-03-11 Rafael Cardoso Maciel Costa Silva
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Assessing the steroid-sparing effect of biological agents in randomized controlled trials for lupus: a scoping review Immunol. Res. (IF 4.4) Pub Date : 2024-03-09 Savino Sciascia, Silvia Grazietta Foddai, Marta Arbrile, Massimo Radin, Irene Cecchi, Alice Barinotti, Roberta Fenoglio, Dario Roccatello
Prompt disease control of flares in patients with systemic lupus erythematosus (SLE) is a priority in treatment strategy planning. However, the long-term dosage-related collateral effects of glucocorticoids (GCs) have pushed researchers towards the identification and utilization of novel biological agents that could both induce and maintain low disease activity and remission, especially in the context
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Involvement of gut microbiota in multiple sclerosis—review of a new pathophysiological hypothesis and potential treatment target Immunol. Res. (IF 4.4) Pub Date : 2024-03-06 Piotr Olejnik, Kasper Buczma, Agnieszka Cudnoch-Jędrzejewska, Kaja Kasarełło
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Monophosphoryl lipid A as a co-adjuvant in methicillin-resistant Staphylococcus aureus vaccine development: improvement of immune responses in a mouse model of infection Immunol. Res. (IF 4.4) Pub Date : 2024-02-21 Mehdi Mirshekar, Setareh Haghighat, Zahra Mousavi, Amir Hossein Abdolghaffari, Mohammad Hossein Yazdi
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Mass cytometry revealed the circulating immune cell landscape across different Suzuki stages of Moyamoya disease Immunol. Res. (IF 4.4) Pub Date : 2024-02-20 Chenglong Liu, Peicong Ge, Bojian Zhang, Liujia Chan, Yuheng Pang, Chuming Tao, Junsheng Li, Qiheng He, Wei Liu, Siqi Mou, Zhiyao Zheng, Zhikang Zhao, Wei Sun, Qian Zhang, Rong Wang, Yan Zhang, Wenjing Wang, Dong Zhang, Jizong Zhao
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Acute stress transiently activates macrophages and chemokines in cervical lymph nodes Immunol. Res. (IF 4.4) Pub Date : 2024-02-14 Akihiro Dohi, Tadahide Noguchi, Masako Yamashita, Kenichi Sasaguri, Toshiharu Yamamoto, Yoshiyuki Mori
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Chronic hyperglycemia impairs anti-microbial function of macrophages in response to Mycobacterium tuberculosis infection Immunol. Res. (IF 4.4) Pub Date : 2024-02-12 Gaurav Kumar Chaubey, Radheshyam Modanwal, Rahul Dilawari, Sharmila Talukdar, Asmita Dhiman, Surbhi Chaudhary, Anil Patidar, Chaaya Iyengar Raje, Manoj Raje
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Rapid generation of an RBL cellular model to study proteins that cause allergenic reactions in vitro Immunol. Res. (IF 4.4) Pub Date : 2024-02-09 Israel Hernández-Aguilar, Juan Carlos Vizuet-de-Rueda, Miguel Ángel Galván-Morales, Josaphat Miguel Montero-Vargas, Luis M. Teran
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Study of pathogenic T-helper cell subsets in Asian Indian patients with Takayasu arteritis Immunol. Res. (IF 4.4) Pub Date : 2024-02-08 P. M. Punithavathy, Ramesh Babu Telugu, Vinay Murahari Rao, Savit B. Prabhu, Jayakanthan Kabeerdoss, Chanduni Syed, George Joseph, Debashish Danda, Meera Thomas, Ruchika Goel
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Blood and CSF anti-neuronal antibodies testing in psychotic syndromes: a retrospective analysis from a tertiary psychiatric hospital Immunol. Res. (IF 4.4) Pub Date : 2024-01-31 Joana Lopes, Maria João Malaquias, Joana Freitas, Rodrigo Valido, Paula Carneiro, Esmeralda Neves, Ana Maria Moreira, Raquel Samões, Ernestina Santos, Ana Paula Correia
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Rituximab alleviates pediatric systemic lupus erythematosus associated refractory immune thrombocytopenia: a case-based review Immunol. Res. (IF 4.4) Pub Date : 2024-01-27 Fangxin Mu, Xue Bai, Yan Lou, Ping Luo, Qiaoyan Guo
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Evidence of concerning decline of COVID-19 vaccination in older persons Immunol. Res. (IF 4.4) Pub Date : 2024-01-26 Camilla Mattiuzzi, Giuseppe Lippi
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The immune regulatory function of B7-H3 in malignancy: spotlight on the IFN-STAT1 axis and regulation of tumor-associated macrophages Immunol. Res. (IF 4.4) Pub Date : 2024-01-24 Robin Park, James Yu, Moazzam Shazad, Sunggon Lee, Jong Dae Ji
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Characteristics of splenic PD-1+ γδT cells in Plasmodium yoelii nigeriensis infection Immunol. Res. (IF 4.4) Pub Date : 2024-01-24 Dianhui Chen, Feng Mo, Meiling Liu, Lin Liu, Junmin Xing, Wei Xiao, Yumei Gong, Shanni Tang, Zhengrong Tan, Guikuan Liang, Hongyan Xie, Jun Huang, Juan Shen, Xingfei Pan
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Evolutionary preservation of CpG dinucleotides in RAG1 may elucidate the relatively high rate of methylation-mediated mutagenesis of RAG1 transposase Immunol. Res. (IF 4.4) Pub Date : 2024-01-19 Mariam M. Fawzy, Maiiada H. Nazmy, Azza A. K. El-Sheikh, Moustafa Fathy
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DNA methylation profiling of labial salivary gland tissues revealed hypomethylation of B-cell-related genes in primary Sjögren’s syndrome Immunol. Res. (IF 4.4) Pub Date : 2024-01-18 Jayakanthan Kabeerdoss, Prabavathi Devarajalu, Pulukool Sandhya
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Response to: regarding the significance of anti-COVID-IgA antibody response in COVID-19 breakthrough infection Immunol. Res. (IF 4.4) Pub Date : 2024-01-05 Sabiha Anis, Mariam Ashfaq Khan, Areej Fatima, Fatima Kanani, Javeria Aijaz, Aneela Hussain, Samreen Sarfaraz
In response to Chen et al.’s comments on our paper regarding the significance of anti-COVID-IgA antibody response in COVID-19 breakthrough infection in vaccinated patients, we have highlighted the role and the scope of this paper in this correspondence. The role of anti-COVID-19-IgA is already known. The objective of the previous study was to see its role in breakthrough-infected patients. To analyse
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The combination of IDO and AHR blockers reduces the migration and clonogenicity of breast cancer cells Immunol. Res. (IF 4.4) Pub Date : 2023-12-28 Maryam Soltani-asl, Parviz Azimnasab-sorkhabi, Tulio Teruo Yoshinaga, Cristina de Oliveira Massoco, Jose Roberto Kfoury
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Conventional Tregs in treatment-naïve rheumatoid arthritis are deficient in suppressive function with an increase in percentage of CXCR3 and CCR6 expressing Tregs Immunol. Res. (IF 4.4) Pub Date : 2023-12-27 Vallayyachari Kommoju, Christina Mary Mariaselvam, Sree Nethra Bulusu, Chengappa Kavadichanda Ganapathy, Prakash Babu Narasimhan, Molly Mary Thabah, Vir Singh Negi
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Serum soluble LYVE1 is a promising non-invasive biomarker of renal fibrosis: a population-based retrospective cross-sectional study Immunol. Res. (IF 4.4) Pub Date : 2023-12-23 Jing Liu, Yuqing Liu, Wenqian Zhou, Yiguo Liu, Saiya Zhu, Ying Yu, Jieli Huang, Chen Yu
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COVID-19 in Systemic Lupus Erythematosus patients treated with belimumab: a retrospective clinical study Immunol. Res. (IF 4.4) Pub Date : 2023-12-22 Yinlan Wu, Yanhong Li, Tong Wu, Deying Huang, Jianhong Wu, Weihua Zhang, Xuejun Jiang, Chaoqiong Yao, Xiuping Liang, Lu Cheng, Zehui Liao, Fang Xu, Chunyu Tan, Yi Liu, Martin Herrmann
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An epicutaneous therapeutic pollen-allergen extract delivery system in an allergic rhinitis mouse model: based on allergen loading on DC-specific aptamers conjugated nanogolds Immunol. Res. (IF 4.4) Pub Date : 2023-12-13 Safoora Pordel, Navideh Haghnavaz, MohammadAli Rezaee, Saeideh Sadat Shobeiri, Bahareh Ansari, Mohammadreza Dashti, Malihe Moghadam, Motahare Khorrami, Mojtaba Sankian
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Quantitative evaluation of citrullinated fibrinogen for detection of neutrophil extracellular traps Immunol. Res. (IF 4.4) Pub Date : 2023-12-12 Tsubasa Sue, Tomoki Ichikawa, Shu Hattori, Hikaru Otani, Satoshi Fujimura, Tsukasa Higuchi, Nobuo Okumura, Yumiko Higuchi
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Long non-coding RNA ENSMUST00000197208 promotes a shift in the Th17/Treg ratio via the P2X7R-NLRP3 inflammasome axis in collagen-induced arthritis Immunol. Res. (IF 4.4) Pub Date : 2023-12-08 Yuting Pan, Yan Wu, Yingying Liu, Panpan Wang, Hui Huang, Jing Jin, Yuying Fang, Shuoyin Huang, Zhidan Fan, Haiguo Yu
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Immune cells and hypertension Immunol. Res. (IF 4.4) Pub Date : 2023-12-04 Liren Gan, Di Ye, Yongqi Feng, Heng Pan, Xiyi Lu, Jun Wan, Jing Ye
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A ubiquitin–proteasome system-related signature to predict prognosis, immune infiltration, and therapy efficacy for breast cancer Immunol. Res. (IF 4.4) Pub Date : 2023-12-01 Xiao Liu, Meihuan Wang, Qian Wang, Huawei Zhang
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Fructus lycii oligosaccharide alleviates acute liver injury via PI3K/Akt/mTOR pathway Immunol. Res. (IF 4.4) Pub Date : 2023-11-30 Zhe Wang, Xingxing Zhang, De ming Lv, Sucheng Cao, Guang Yang, Zhijian Zhang, Qingtong Yu
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Impact of microparticles released during murine systemic inflammation on macrophage activity and reactive nitrogen species regulation Immunol. Res. (IF 4.4) Pub Date : 2023-11-27 Weronika Ortmann, Anna Such, Elzbieta Kolaczkowska
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Comparative analyses of various IgE-mediated and non-IgE-mediated inducers of mast cell degranulation for in vitro study Immunol. Res. (IF 4.4) Pub Date : 2023-11-25 Sunisa Yoodee, Chuda Rujitharanawong, Kanyarat Sueksakit, Papapit Tuchinda, Kanokvalai Kulthanan, Visith Thongboonkerd
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Semaphorin 3 a restores the ability of type 1 regulatory T cells to suppress food allergy Immunol. Res. (IF 4.4) Pub Date : 2023-11-24 Panpan Gao, Shuo Song, Yanan Wang, Huazhen Liu, Xiangyu Wang, Qing shu, Pingchang Yang, Pengyuan Zheng
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Insights into the immunological description of cryoglobulins with regard to detection and characterization in Slovenian rheumatological patients Immunol. Res. (IF 4.4) Pub Date : 2023-11-23 Manca Ogrič, Tinka Švec, Katjuša Mrak Poljšak, Katja Lakota, Eva Podovšovnik, Marie Nathalie Kolopp-Sarda, Alojzija Hočevar, Saša Čučnik
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Increased synthesis and intestinal expression of IL-39 in patients with inflammatory bowel disease Immunol. Res. (IF 4.4) Pub Date : 2023-11-16 Gabriela Fonseca-Camarillo, Janette Furuzawa-Carballeda, Rafael Barreto-Zúñiga, Braulio Martínez-Benítez, Jesús K. Yamamoto-Furusho
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Role of LINC00240 on T-helper 9 differentiation in allergic rhinitis through influencing DNMT1-dependent methylation of PU.1 Immunol. Res. (IF 4.4) Pub Date : 2023-11-15 JianGuo Liu, XunShuo Jiang, Ke Liu, JianJian Deng, Yi Qiu, Wan Wei, ChunPing Yang
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Association of IL-23R and IL-10 variations with Behçet disease: a genetic analysis study Immunol. Res. (IF 4.4) Pub Date : 2023-11-13 Guven Yenmis, Sema Sabancelebi, Evren Atak, Sila Basak Yalinkilic, Tugba Soydas, Tumay Sadikoglu
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Prevalence and sociodemographic correlates of antinuclear antibody testing by indirect immunofluorescence or solid-phase assays in a Spanish population: the Camargo Cohort Immunol. Res. (IF 4.4) Pub Date : 2023-11-04 Juan Irure-Ventura, Daniel Martínez-Revuelta, Marcos López-Hoyos, Marta Martín-Millán, Daniel Nan, Emilio Pariente, Javier Pardo-Lledías, Alejandra Comins-Boo, José Manuel Olmos, Víctor Manuel Martínez-Taboada, José Luis Hernández
Autoantibodies are the hallmark of autoimmunity, and specifically, antinuclear antibodies (ANA) are one of the most relevant antibodies present in systemic autoimmune diseases (AID). In the present study, we evaluate the relationship between ANA and sociodemographic and biobehavioral factors in a population with a low pre-test probability for systemic AID. ANA were determined in serum samples at baseline
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Rational design of multi-epitope-based vaccine by exploring all dengue virus serotypes proteome: an immunoinformatic approach Immunol. Res. (IF 4.4) Pub Date : 2023-10-25 Ahad Amer Alsaiari, Mohammed Ageeli Hakami, Bader S. Alotaibi, Samia S. Alkhalil, Ali Hazazi, Nada Alkhorayef, Khurshid Jalal, Farzana Yasmin
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Association study between killer immunoglobulin-like receptor polymorphisms and susceptibility to COVID-19 disease: a systematic review and meta-analysis Immunol. Res. (IF 4.4) Pub Date : 2023-10-24 Saeed Hosseini Teshnizi, Sara Mirzazadeh, Niloofar Mashhadi, Seppo Meri, Dieter Kabelitz, Kurosh Kalantar
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Differential expression of TOB/BTG family members in patients with plaque psoriasis: cross-sectional study Immunol. Res. (IF 4.4) Pub Date : 2023-10-24 Carlos A. Barrera-Ochoa, Gabriela Fonseca-Camarillo, María Elisa Vega-Memije, Janette Furuzawa-Carballeda, Karen Uriarte-Ruiz, Dheni Aidé Fernández-Camargo, Jesús K. Yamamoto-Furusho
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Palpitation in women with silicone breast implants: association with autoantibodies against autonomic nervous system Immunol. Res. (IF 4.4) Pub Date : 2023-10-16 Tal Elroy, Gilad Halpert, Avishai M. Tsur, Harald Heidecke, Howard Amital, Yehuda Shoenfeld
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Current genetic defects in common variable immunodeficiency patients on the geography between Europe and Asia: a single-center experience Immunol. Res. (IF 4.4) Pub Date : 2023-10-16 Ayse Aygun, Ezgi Topyıldız, Mehmet Geyik, Neslihan Edeer Karaca, Asude Durmaz, Guzide Aksu, Ayca Aykut, Necil Kutukculer
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Harmonization of ANA testing challenge: quantification strategy to accurately predict end-point titers avoiding serial dilution Immunol. Res. (IF 4.4) Pub Date : 2023-10-04 Teresa Carbone, Vito Pafundi, Vito Ciardo, Maria Infantino, Antonella Muscella, Salvatore D’Angelo
Despite the advantages of automated systems for antinuclear antibody (ANA) analysis, the prediction of end-point titers avoiding serial dilutions is still in progress. The aims of this study were to set a conversion table providing discriminant ranges of fluorescence signal intensity values (FI) corresponding to the end-point titers and validate this tool in a real-life laboratory setting. Eight hundred
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MiR-7 deficiency promotes Th1 polarization of CD4+T cells and enhances the antitumor effect in adoptive cell therapy for lung cancer Immunol. Res. (IF 4.4) Pub Date : 2023-09-27 Xian Chang, Juanjuan Zhao, Ya Zhou, Mengmeng Guo, Yaping Yan, Ya Wang, Xu Zhao, Jing Yang, Chao Chen, Lin Tang, Ming Qin, Lin Xu
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Elevated neutrophil-lymphocyte ratio is associated with high rates of ICU mortality, length of stay, and invasive mechanical ventilation in critically ill patients with COVID-19 Immunol. Res. (IF 4.4) Pub Date : 2023-09-28 Heitor O. Santos, Felipe M. Delpino, Octavio M. Veloso, Juliana M. R. Freire, Erlaine S. N. Gomes, Cristina G. M. Pereira
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Diverse functions of myeloid-derived suppressor cells in autoimmune diseases Immunol. Res. (IF 4.4) Pub Date : 2023-09-21 Xin Xiong, Yang Zhang, Yu Wen
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Total serum IgA levels and HLA-DQB1*02:01 allelic status Immunol. Res. (IF 4.4) Pub Date : 2023-09-19 Diyora Abdukhakimova, Malika Ibrayeva, Kuanysh Dossybayeva, Aida Turganbekova, Zhuldyz Zhanzakova, Saniya Abdrakhmanova, Pauline McLoone, Dimitri Poddighe
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ANCA detection with solid phase chemiluminescence assay: diagnostic and severity association in vasculitis Immunol. Res. (IF 4.4) Pub Date : 2023-09-07 Mónica Renuncio-García, Vanesa Calvo-Río, Fabricio Benavides-Villanueva, Salma Al Fazazi, María Rodríguez-Vidriales, Clara Escagedo-Cagigas, Luis Martín-Penagos, Juan Irure-Ventura, Marcos López-Hoyos, Ricardo Blanco
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Nanotechnology-based theranostic and prophylactic approaches against SARS-CoV-2 Immunol. Res. (IF 4.4) Pub Date : 2023-09-08 Atika Dhar, Sneh Lata Gupta, Pratima Saini, Kirti Sinha, Ankita Khandelwal, Rohit Tyagi, Alka Singh, Priyanka Sharma, Rishi Kumar Jaiswal
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MICA and NLRP3 gene polymorphisms interact synergistically affecting the risk of ankylosing spondylitis Immunol. Res. (IF 4.4) Pub Date : 2023-09-04 Javier Fernández-Torres, Yessica Zamudio-Cuevas, Xiadani Ruiz-Dávila, Ambar López-Macay, Karina Martínez-Flores
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How the immune response to the structural proteins of SARS-CoV-2 affects the retinal vascular endothelial cells: an immune thrombotic and/or endotheliopathy process with in silico modeling Immunol. Res. (IF 4.4) Pub Date : 2023-08-29 Işıl Kutlutürk, Ecem Önder Tokuç, Levent Karabaş, René Rückert, Mücahit Kaya, Ali Karagöz, Marion R Munk
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A high affinity and specificity anti-HER2 single-domain antibody (VHH) that targets trastuzumab’s epitope with versatile biochemical, biological, and medical applications Immunol. Res. (IF 4.4) Pub Date : 2023-08-26 Shahryar Khoshtinat Nikkhoi, Hediyeh Heydarzadeh, Venu Gopal Vandavasi, Ge Yang, Pedro Louro, Marianne Polunas, Hajar Owji, Arash Hatefi
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Dominance and improved survivability of human γδT17 cell subset aggravates the immunopathogenesis of pemphigus vulgaris Immunol. Res. (IF 4.4) Pub Date : 2023-08-24 Dayasagar Das, Sudheer Arava, Sujay Khandpur, KV Santosh, Shamima Akhtar, Alpana Sharma
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Integrating core subtractive proteomics and reverse vaccinology for multi-epitope vaccine design against Rickettsia prowazekii endemic typhus Immunol. Res. (IF 4.4) Pub Date : 2023-08-22 Ariba Khan, Muhammad Hassan Khanzada, Kanwal Khan, Khurshid Jalal, Reaz Uddin
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Mediastinal lymph node removal modulates natural killer cell exhaustion in patients with non-small cell lung cancer Immunol. Res. (IF 4.4) Pub Date : 2023-08-16 Duygu Ilke Cikman, Fehim Esen, Ayse Engin, Akif Turna, Melek Agkoc, Abdullah Yilmaz, Omer Faruk Saglam, Gunnur Deniz, Esin Cetin Aktas
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Autoimmune lymphoproliferative syndrome (ALPS) due to a novel dominant negative germline mutation in the FAS gene Immunol. Res. (IF 4.4) Pub Date : 2023-08-07 Beatriz Rodríguez-Bayona, José Manuel Lucena-Soto, Borja Croché-Santander, Peter Olbrich, María Francisca González-Escribano, Olaf Neth
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Transcriptional upregulation of galectin-3 in multiple sclerosis Immunol. Res. (IF 4.4) Pub Date : 2023-07-25 Katia Mangano, Maria Cristina Petralia, Rita Bella, Manuela Pennisi, José Francisco Muñoz-Valle, Jorge Hernández-Bello, Ferdinando Nicoletti, Paolo Fagone
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Significance of Anti-COVID-IgA antibody response in COVID-19 breakthrough infection in vaccinated patients – a single-centered study from Pakistan Immunol. Res. (IF 4.4) Pub Date : 2023-07-12 Sabiha Anis, Mariam Ashfaq Khan, Areej Fatima, Fatima Kanani, Javeria Aijaz, Aneela Hussain, Samreen Sarfaraz
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Pan-genome and reverse vaccinology approaches to design multi-epitope vaccine against Epstein-Barr virus associated with colorectal cancer Immunol. Res. (IF 4.4) Pub Date : 2023-07-10 P. Priyamvada, Sudha Ramaiah
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Translational and structural vaccinomics approach to design a multi-epitope vaccine against NOL4 autologous antigen of small cell lung cancer Immunol. Res. (IF 4.4) Pub Date : 2023-07-06 Pavithran G, Bhawna Rathi, Seneha Santoshi
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The expression of CD86 in CD3+CD56+ NKT cells is associated with the occurrence and prognosis of sepsis-associated encephalopathy in sepsis patients: a prospective observational cohort study Immunol. Res. (IF 4.4) Pub Date : 2023-07-05 Sheng-long Chen, Xiao-yu Liu, Jun-hong Huang, Lu-hua Xian, Xu-sheng Li, Kang-rong Wang, Jing Li, Tian-cao Zhang, Guo-ge Huang, Xin-qiang Liu, Hong-ke Zeng, Mao-hua Zhou, Wen-qiang Jiang
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Chronic inflammatory demyelinating polyneuropathy after SARS-CoV2 vaccination: update of the literature and patient characterization Immunol. Res. (IF 4.4) Pub Date : 2023-07-03 Federica Ginanneschi, Claudia Vinciguerra, Nila Volpi, Giuseppe Piscosquito, Paolo Barone, Alessandro Rossi