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Glioblastoma Cells Use an Integrin- and CD44-Mediated Motor-Clutch Mode of Migration in Brain Tissue Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2024-03-04 Sarah M. Anderson, Marcus Kelly, David J. Odde
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Three-Dimensional Tumor Models to Study Cancer Stemness-Mediated Drug Resistance Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2024-02-21 Astha Lamichhane, Hossein Tavana
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Pathological Features of Colorectal Adenocarcinoma Patients Related to MLH1 Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2024-02-20
Abstract Background MLH1, one of the MMR proteins, is linked to DNA replication, its role being to repair the incorrect DNA sequences and to replace them with proper ones. The loss of the MLH1 gene expression is part of Lynch syndrome which can lead to a series of cancers like colorectal and endometrial ones. The aim of this paper is to correlate the levels of MLH1 in four different bio-logical fluids
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A Model for Chemomechanical Coupling of Kinesin-3 Motor Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2024-02-18 Ping Xie
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Influence of Hematocrit Level and Integrin αIIbβIII Function on vWF-Mediated Platelet Adhesion and Shear-Induced Platelet Aggregation in a Sudden Expansion Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2024-02-16
Abstract Purpose Shear-mediated thrombosis is a clinically relevant phenomenon that underlies excessive arterial thrombosis and device-induced thrombosis. Red blood cells are known to mechanically contribute to physiological hemostasis through margination of platelets and vWF, facilitating the unfurling of vWF multimers, and increasing the fraction of thrombus-contacting platelets. Shear also plays
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Neurogenic Cell Behavior in 3D Culture Enhanced Within a Highly Compliant Synthetic Hydrogel Platform Formed via Competitive Crosslinking Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2024-02-12
Abstract Purpose Scaffold materials that better support neurogenesis are still needed to improve cell therapy outcomes for neural tissue damage. We have used a modularly tunable, highly compliant, degradable hydrogel to explore the impacts of hydrogel compliance stiffness on neural differentiation. Here we implemented competitive matrix crosslinking mechanics to finely tune synthetic hydrogel moduli
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Incorporation of ChatGPT and Other Large Language Models into a Graduate Level Computational Bioengineering Course Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2024-02-07 Michael R. King, Adam M. Abdulrahman, Mark I. Petrovic, Patricia L. Poley, Sarah P. Hall, Surat Kulapatana, Zachary E. Lamantia
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Relatively Rare Populations of Invasive Cells Drive Progression of Heterogeneous Tumors Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2024-01-05 Susan E. Leggett, Molly C. Brennan, Sophia Martinez, Joe Tien, Celeste M. Nelson
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Trisomy 21 Alters Cell Proliferation and Migration of iPSC-Derived Cardiomyocytes on Type VI Collagen Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2024-01-03 Rachel S. Reeser, Alyssa K. Salazar, Kendra M. Prutton, James R. Roede, Mitchell C. VeDepo, Jeffrey G. Jacot
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Investigating the Influence of Heterogeneity Within Cell Types on Microvessel Network Transport Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-11-29 Junyu Nan, Sayan Roychowdhury, Amanda Randles
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Three-Dimensional Fractal Analysis of the Interstitial Cells of Cajal Networks of Gastrointestinal Tissue Specimens Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-11-27 Sue Ann Mah, Recep Avci, Jean-Marie Vanderwinden, Peng Du
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The 2023 CMBE Young Innovators: ChatGPT Gets the Final Word Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-10-30 Alisa Morss Clyne, Owen J. T. McCarty, Michael R. King
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Head-to-Head Comparison of CCN4, DNMT3A, PTPN11, and SPARC as Suppressors of Anti-tumor Immunity Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-10-28 Anika C. Pirkey, Wentao Deng, Danielle Norman, Atefeh Razazan, David J. Klinke
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Engineered Extracellular Vesicle-Based Therapies for Valvular Heart Disease Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-09-26 Ana I. Salazar-Puerta, Mia Kordowski, Tatiana Z. Cuellar-Gaviria, Maria A. Rincon-Benavides, Jad Hussein, Dorma Flemister, Gabriel Mayoral-Andrade, Grant Barringer, Elizabeth Guilfoyle, Britani N. Blackstone, Binbin Deng, Diana Zepeda-Orozco, David W. McComb, Heather Powell, Lakshmi P. Dasi, Daniel Gallego-Perez, Natalia Higuita-Castro
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Elucidating Mechanotransduction Processes During Magnetomechanical Neuromodulation Mediated by Magnetic Nanodiscs Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-09-20 Amanda Gomez, Nicolas Muzzio, Ania Dudek, Athena Santi, Carolina Redondo, Raquel Zurbano, Rafael Morales, Gabriela Romero
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Nuclear Entry of DNA and Transgene Expression in Dividing and Non-dividing Cells Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-09-17 Justin Sylvers, Yifei Wang, Fan Yuan
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siRNA Lipid–Polymer Nanoparticles Targeting E-Selectin and Cyclophilin A in Bone Marrow for Combination Multiple Myeloma Therapy Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-09-14 Christian G. Figueroa-Espada, Pedro P. G. Guimarães, Rachel S. Riley, Lulu Xue, Karin Wang, Michael J. Mitchell
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Amyloid-β Pathology-Specific Cytokine Secretion Suppresses Neuronal Mitochondrial Metabolism Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-09-11 Madison K. Kuhn, Rebecca M. Fleeman, Lynne M. Beidler, Amanda M. Snyder, Dennis C. Chan, Elizabeth A. Proctor
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A 3D Human Lymphatic Vessel-on-Chip Reveals the Roles of Interstitial Flow and VEGF-A/C for Lymphatic Sprouting and Discontinuous Junction Formation Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-08-24 Isabelle S. Ilan, Aria R. Yslas, Yansong Peng, Renhao Lu, Esak Lee
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Optogenetic Modulation of Arrhythmia Triggers: Proof-of-Concept from Computational Modeling Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-08-24 Alexander R. Ochs, Patrick M. Boyle
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Altered Caveolin-1 Dynamics Result in Divergent Mineralization Responses in Bone and Vascular Calcification Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-08-19 Amirala Bakhshian Nik, Katherine Kaiser, Patrick Sun, Bohdan B. Khomtchouk, Joshua D. Hutcheson
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Engineering of Trophoblast Extracellular Vesicle-Delivering Hydrogels for Localized Tolerance Induction in Cell Transplantation Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-08-17 Shivani C. Hiremath, Jessica D. Weaver
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Peristalsis-Associated Mechanotransduction Drives Malignant Progression of Colorectal Cancer Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-08-11 Abigail J. Clevenger, Maygan K. McFarlin, Claudia A. Collier, Vibha S. Sheshadri, Anirudh K. Madyastha, John Paul M. Gorley, Spencer C. Solberg, Amber N. Stratman, Shreya A. Raghavan
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Outsourcing Your Faculty Application to ChatGPT: Would this Work? Should this Work? Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-08-10 Michael R King
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Irradiated Mammary Spheroids Elucidate Mechanisms of Macrophage-Mediated Breast Cancer Recurrence Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-08-01 Benjamin C. Hacker, Erica J. Lin, Dana C. Herman, Alyssa M. Questell, Shannon E. Martello, Rebecca J. Hedges, Anesha J. Walker, Marjan Rafat
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Single-Cell Proliferation Microfluidic Device for High Throughput Investigation of Replicative Potential and Drug Resistance of Cancer Cells Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-07-28 Adity A. Pore, Nabiollah Kamyabi, Swastika S. Bithi, Shamim M. Ahmmed, Siva A. Vanapalli
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The Effect of Substrate Stiffness on Elastic Force Transmission in the Epithelial Monolayers over Short Timescales Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-07-13 Aapo Tervonen, Sanna Korpela, Soile Nymark, Jari Hyttinen, Teemu O. Ihalainen
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Toward Blood-Based Precision Medicine: Identifying Age-Sex-Specific Vascular Biomarker Quantities on Circulating Vascular Cells Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-07-06 Yingye Fang, Ling Chen, P. I. Imoukhuede
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Bio-adhesive Macroporous Hydrogels for In Situ Recruitment and Modulation of Dendritic Cells Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-07-03 Joonsu Han, Rimsha Bhatta, Hua Wang
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Amelioration of Subglottic Stenosis by Antimicrobial Peptide Eluting Endotracheal Tubes Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-06-29 Matthew R. Aronson, Amrita Mehta, Ryan M. Friedman, Daniel D. Ghaderi, Ryan C. Borek, Hoang C. B. Nguyen, Kendra S. McDaid, Ian N. Jacobs, Natasha Mirza, Riccardo Gottardi
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Correction: Innovation and Entrepreneurship in Promotion and Tenure in Biomedical Engineering. Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-05-31 Tia C L Kohs,Samuel N Clarin,Rich G Carter,Karl Mundorff,Princess I Imoukhuede,Anand Ramamurthi,Gang Bao,Michael R King,Owen J T McCarty
[This corrects the article DOI: 10.1007/s12195-023-00767-x.].
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Innovation and Entrepreneurship in Promotion and Tenure in Biomedical Engineering: Communication from the Biomedical Engineering Society Long Range Planning Committee Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-05-19 Tia C. L. Kohs, Samuel N. Clarin, Rich G. Carter, Karl Mundorff, Princess I. Imoukhuede, Anand Ramamurthi, Gang Bao, Michael R. King, Owen J. T. McCarty
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Contact Guidance Drives Upward Cellular Migration at the Mesoscopic Scale Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-05-01 Xiaoxiao Chen, Youjun Xia, Wenqiang Du, Han Liu, Ran Hou, Yiyu Song, Wenhu Xu, Yuxin Mao, Jianfeng Chen
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A Place for Large Language Models in Scientific Publishing, Apart from Credited Authorship. Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-04-13 Michael R King
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Caveolin Delivered by Ultrasound-Mediated Microbubble Destruction Prevents Endothelial Cell Proliferation Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-04-12 Iván M. López-Rodulfo, Elisa Villa-Martínez, Amelia Rios, Bruno Escalante
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Angiotensin II Increases Oxidative Stress and Inflammation in Female, But Not Male, Endothelial Cells Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-04-12 Callie M. Weber, Mikayla N. Harris, Sophia M. Zic, Gurneet S. Sangha, Nicole S. Arnold, Douglas F. Dluzen, Alisa Morss Clyne
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TNF-α Preconditioning Promotes a Proangiogenic Phenotype in hiPSC-Derived Vascular Smooth Muscle Cells Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-04-08 Daniel C. Sasson, Sara Islam, Kaiti Duan, Biraja C. Dash, Henry C. Hsia
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Can Bard, Google’s Experimental Chatbot Based on the LaMDA Large Language Model, Help to Analyze the Gender and Racial Diversity of Authors in Your Cited Scientific References? Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-04-03 Michael R. King
There is a growing recognition that scientific articles featuring women and people of color as first and last (senior) author are undercited in the literature relative to male and non-minority race authors. Some limited tools now exist to analyze the diversity of manuscript bibliographies, with acknowledged limitations. Recently the journal editors and publications chair of the Biomedical Engineering
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An Integrative Biology Approach to Quantify the Biodistribution of Azidohomoalanine In Vivo Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-03-23 Aya M. Saleh, Tyler G. VanDyk, Kathryn R. Jacobson, Shaheryar A. Khan, Sarah Calve, Tamara L. Kinzer-Ursem
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Artificial Intelligence, Chatbots, Plagiarism and Basic Honesty: Comment. Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-02-17 Amnuay Kleebayoon,Viroj Wiwanitkit
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Circ_0004585 Facilitates Tumorigenesis of Colorectal Cancer Via Modulating the miR-338-3p/ZFX Axis and Activating the MEK/ERK Pathway Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-01-20 Zenghai Lin, Jianwei Lin
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Tumor-Targeting Extracellular Vesicles Loaded with siS100A4 for Suppressing Postoperative Breast Cancer Metastasis Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-01-17 Ruiling Pan, Tiancheng He, Kun Zhang, Lewei Zhu, Jiawei Lin, Peixian Chen, Xiangwei Liu, Huiqi Huang, Dan Zhou, Wei Li, Shuqing Yang, Guolin Ye
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Investigation of the Therapeutic Effects of Palbociclib Conjugated Magnetic Nanoparticles on Different Types of Breast Cancer Cell Lines Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-01-07 Maryam Parsian, Pelin Mutlu, Negar Taghavi Pourianazar, Serap Yalcin Azarkan, Ufuk Gunduz
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A Conversation on Artificial Intelligence, Chatbots, and Plagiarism in Higher Education Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2023-01-02 Michael R. King
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The Applications and Challenges of the Development of In Vitro Tumor Microenvironment Chips Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2022-12-26 Annika Johnson, Samuel Reimer, Ryan Childres, Grace Cupp, Tia C. L. Kohs, Owen J. T. McCarty, Youngbok (Abraham) Kang
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Combining Metformin and Drug-Loaded Kidney-Targeting Micelles for Polycystic Kidney Disease Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2022-12-22 Kairui Jiang, Yi Huang, Eun Ji Chung
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Enhancing Neurological Competence of Nanoencapsulated Cordyceps/Turmeric Extracts in Human Neuroblastoma SH-SY5Y Cells Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2022-12-13 Palakorn Kaokaen, Natchadaporn Sorraksa, Ruchee Phonchai, Nipha Chaicharoenaudomrung, Phongsakorn Kunhorm, Parinya Noisa
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Adipose Cells Induce Escape from an Engineered Human Breast Microtumor Independently of their Obesity Status Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2022-12-09 Yoseph W. Dance, Mackenzie C. Obenreder, Alex J. Seibel, Tova Meshulam, Joshua W. Ogony, Nikhil Lahiri, Laura Pacheco-Spann, Derek C. Radisky, Matthew D. Layne, Stephen R. Farmer, Celeste M. Nelson, Joe Tien
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Stiffer-Matrix-Induced PGC-1α Upregulation Enhanced Mitochondrial Biogenesis and Oxidative Stress Resistance in Non-small Cell Lung Cancer Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2022-12-02 Xiaorong Fu, Yasuhiro Kimura, Yuhki Toku, Guanbin Song, Yang Ju
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Osmotic Contribution of Synthesized Betaine by Choline Dehydrogenase Using In Vivo and In Vitro Models of Post-traumatic Syringomyelia Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2022-11-27 Dipak D. Pukale, Daria Lazarenko, Siddhartha R. Aryal, Fardin Khabaz, Leah P. Shriver, Nic D. Leipzig
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Agent-Based Models Help Interpret Patterns of Clinical Drug Resistance by Contextualizing Competition Between Distinct Drug Failure Modes Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2022-11-15 Scott M. Leighow, Ben Landry, Michael J. Lee, Shelly R. Peyton, Justin R. Pritchard
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Role of Lymphatic Endothelium in Vascular Escape of Engineered Human Breast Microtumors Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2022-11-07 Alex J. Seibel, Owen M. Kelly, Yoseph W. Dance, Celeste M. Nelson, Joe Tien
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Chondrogenesis of Adipose-Derived Stem Cells Using an Arrayed Spheroid Format Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2022-10-22 Robert A. Gutierrez, Vera C. Fonseca, Eric M. Darling
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Encapsulation of Manganese Porphyrin in Chondroitin Sulfate-A Microparticles for Long Term Reactive Oxygen Species Scavenging Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2022-10-14 Fei San Lee, Kayla E. Ney, Alexandria N. Richardson, Rebecca E. Oberley-Deegan, Rebecca A. Wachs
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Lactate Production can Function to Increase Human Epithelial Cell Iron Concentration Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2022-10-12 Caroline Ghio, Joleen M. Soukup, Lisa A. Dailey, Andrew J. Ghio, Dina M. Schreinemachers, Ryan A. Koppes, Abigail N. Koppes
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Generating an In Vitro Gut Model with Physiologically Relevant Biophysical Mucus Properties Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2022-10-06 Jacob McCright, Arnav Sinha, Katharina Maisel
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Light Activates Cdc42-Mediated Needle-Shaped Filopodia Formation via the Integration of Small GTPases Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2022-10-06 Lingling Liu, Ran Sui, Lianxin Li, Lin Zhang, Dong Zeng, Xueqin Ni, Jinghui Sun
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Chemotherapy Dose Shapes the Expression of Immune-Interacting Markers on Cancer Cells Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2022-10-01 Alexander J. Najibi, Kerry Larkin, Zhaoqianqi Feng, Nicholas Jeffreys, Mason T. Dacus, Yashika Rustagi, F. Stephen Hodi, David J. Mooney
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Development of Serum-Free Media for Cryopreservation of Hydrogel Encapsulated Cell-Based Therapeutics Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2022-09-29 Yufei Cui, Amanda M. Nash, Bertha Castillo, Leonardo D. Sanchez Solis, Samira Aghlara-Fotovat, Maya Levitan, Boram Kim, Michael Diehl, Omid Veiseh
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Plant Tissue Parenchyma and Vascular Bundles Selectively Regulate Stem Cell Mechanosensing and Differentiation Cel. Mol. Bioeng. (IF 2.8) Pub Date : 2022-09-20 Kathryn Driscoll, Maya S. Butani, Kirstene A. Gultian, Abigail McSweeny, Jay M. Patel, Sebastián L. Vega