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Optimizing CRISPR/Cas9 approaches in the polymorphic tunicate Ciona intestinalis Dev. Biol. (IF 2.7) Pub Date : 2024-03-14 Alessandro Pennati, Miloš Jakobi, Fan Zeng, Luca Ciampa, Ute Rothbächer
CRISPR/Cas9 became a powerful tool for genetic engineering and knockout also in the invertebrate chordate . (ascidians, tunicates) is an important model organism because it shares developmental features with the vertebrates, considered the sister group of tunicates, and offers outstanding experimental advantages: a compact genome and an invariant developmental cell lineage that, combined with electroporation
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Mutant analysis of Kcng4b reveals how the different functional states of the voltage-gated potassium channel regulate ear development. Dev. Biol. (IF 2.7) Pub Date : 2024-03-14 Justyna Jędrychowska, Vitya Vardanyan, Milosz Wieczor, Antoni Marciniak, Jacek Czub, Razieh Amini, Ruchi Jain, Hongyuan Shen, Hyungwon Choi, Jacek Kuznicki, Vladimir Korzh
The voltage gated (Kv) slow-inactivating delayed rectifier channel regulates the development of hollow organs of the zebrafish. The functional channel consists of the tetramer of electrically active Kcnb1 (Kv2.1) subunits and Kcng4b (Kv6.4) modulatory or electrically silent subunits. The two mutations in zebrafish gene and (Gasanov et al., 2021) – have been studied during ear development using electrophysiology
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Avian model systems 11 conference 11–14 September 2023 Dev. Biol. (IF 2.7) Pub Date : 2024-03-08 F. Schubert, S. Dietrich, conference chairs
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Anatomy, development and regeneration of zebrafish elasmoid scales Dev. Biol. (IF 2.7) Pub Date : 2024-03-06 Andrew J. Aman, David M. Parichy
Vertebrate skin appendages – particularly avian feathers and mammalian hairs, glands and teeth – are perennially useful systems for investigating fundamental mechanisms of development. The most common type of skin appendage in teleost fishes is the elasmoid scale, yet this structure has received much less attention than the skin appendages of tetrapods. Elasmoid scales are thin, overlapping plates
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Ras/MAPK signaling mediates adipose tissue control of ovarian germline survival and ovulation in Drosophila melanogaster Dev. Biol. (IF 2.7) Pub Date : 2024-02-27 Tancia Bradshaw, Chad Simmons, Rachael Ott, Alissa Richmond Armstrong
From insects to humans, oogenesis is tightly linked to nutritional input, yet little is known about how whole organism physiology matches dietary changes with oocyte development. Considering that diet-induced adipose tissue dysfunction is associated with an increased risk for fertility problems, and other obesity-associated pathophysiologies, it is critical to decipher the cellular and molecular mechanisms
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Circadian clock genes REV-ERBα regulates the secretion of IL-1β in deciduous tooth pulp stem cells by regulating autophagy in the process of physiological root resorption of deciduous teeth Dev. Biol. (IF 2.7) Pub Date : 2024-02-24 Tiankai Di, Mingzhu Guo, Jinlong Xu, Chao Feng, Yang Du, Lulu Wang, Yujiang Chen
Physiological root resorption is a common occurrence during the development of deciduous teeth in children. Previous research has shown that the regulation of the inflammatory microenvironment through autophagy in DDPSCs is a significant factor in this process. However, it remains unclear why there are variations in the autophagic status of DDPSCs at different stages of physiological root resorption
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Tissue-specific compensatory mechanisms maintain tissue architecture and body size independent of cell size in polyploid zebrafish Dev. Biol. (IF 2.7) Pub Date : 2024-02-20 C.D. Small, T.J. Benfey, B.D. Crawford
Genome duplications and ploidy transitions have occurred in nearly every major taxon of eukaryotes, but they are far more common in plants than in animals. Due to the conservation of the nuclear:cytoplasmic volume ratio increased DNA content results in larger cells. In plants, polyploid organisms are larger than diploids as cell number remains relatively constant. Conversely, vertebrate body size does
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Intestinal Mg2+ accumulation induced by cnnm mutations decreases the body size by suppressing TORC2 signaling in Caenorhabditis elegans Dev. Biol. (IF 2.7) Pub Date : 2024-02-17 Osamu Hashizume, Tomofumi Kawabe, Yosuke Funato, Hiroaki Miki
Mg is a vital ion involved in diverse cellular functions by forming complexes with ATP. Intracellular Mg levels are tightly regulated by the coordinated actions of multiple Mg transporters, such as the Mg efflux transporter, cyclin M (CNNM). () worms with mutations in both and exhibit excessive Mg accumulation in intestinal cells, leading to various phenotypic abnormalities. In this study, we investigated
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The BTB transcription factor, Abrupt, acts cooperatively with Chronologically inappropriate morphogenesis (Chinmo) to repress metamorphosis and promotes leg regeneration Dev. Biol. (IF 2.7) Pub Date : 2024-02-17 Hesper Khong, Kayli B. Hattley, Yuichiro Suzuki
Many insects undergo the process of metamorphosis when larval precursor cells begin to differentiate to create the adult body. The larval precursor cells retain stem cell-like properties and contribute to the regenerative ability of larval appendages. Here we demonstrate that two Broad-complex/Tramtrack/Bric-à-brac Zinc-finger (BTB) domain transcription factors, Chronologically inappropriate morphogenesis
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Energy metabolism disorders during in vitro maturation of bovine cumulus-oocyte complexes interfere with blastocyst quality and metabolism Dev. Biol. (IF 2.7) Pub Date : 2024-02-10 Piotr Pawlak, Paulina Lipinska, Ewa Sell-Kubiak, Arkadiusz Kajdasz, Natalia Derebecka, Ewelina Warzych
Glucose and fatty acids (FA) metabolism disturbances during oocyte in vitro maturation (IVM) affect their metabolism and surrounding cumulus cells, but only inhibition of glucose metabolism decreases embryo culture efficiency. Therefore, the present experiment aimed to reveal if glucose or FA metabolism inhibition leads to the disruption of embryo developmental potential, and to characterize the metabolic
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Genome-wide analysis of early vascular tunic repair and regeneration for Botrylloides digenesis reveals striking similarities to human wound healing. Dev. Biol. (IF 2.7) Pub Date : 2024-02-10 Rebecca M. Clarke, Michael Meier, Megan J. Wilson
The early stages of regeneration after injury are similar to those of wound healing. The ascidian can regenerate an entire adult from a small fragment of vascular tunic following the removal of all zooids in an injury-induced regeneration model. We investigated the molecular and cellular changes following injury to determine the differences between the healing process and the initiation of whole-body
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Why study human embryo development? Dev. Biol. (IF 2.7) Pub Date : 2024-02-05 Janet Rossant
Understanding the processes and mechanisms underlying early human embryo development has become an increasingly active and important area of research. It has potential for insights into important clinical issues such as early pregnancy loss, origins of congenital anomalies and developmental origins of adult disease, as well as fundamental insights into human biology. Improved culture systems for preimplantation
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Stage-specific regulation of undifferentiated spermatogonia by AKT1S1-mediated AKT-mTORC1 signaling during mouse spermatogenesis Dev. Biol. (IF 2.7) Pub Date : 2024-02-02 Lele Yang, Jinyue Liao, Hongying Huang, Tin_Lap Lee, Huayu Qi
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Nkx2.3 transcription factor is a key regulator of mucous cell identity in salivary glands Dev. Biol. (IF 2.7) Pub Date : 2024-02-02 Xin Gao, Taro Mukaibo, Xiaolu Wei, Roberta C. Faustoferri, Maria S. Oei, Seo-Kyoung Hwang, Adela Jingyi Yan, James E. Melvin, Catherine E. Ovitt
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microRNA-1 regulates sea urchin skeletogenesis by directly targeting skeletogenic genes and modulating components of signaling pathways Dev. Biol. (IF 2.7) Pub Date : 2024-01-28 Nina Faye Sampilo, Jia L. Song
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Human stem-cell-derived embryo models: When bioethical normativity meets biological ontology Dev. Biol. (IF 2.7) Pub Date : 2024-01-28 Adrian Villalba, Jon Rueda, Íñigo de Miguel Beriain
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Neutrophils facilitate the epicardial regenerative response after zebrafish heart injury Dev. Biol. (IF 2.7) Pub Date : 2024-01-28 Elizabeth A. Peterson, Jisheng Sun, Xin Chen, Jinhu Wang
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Perturbed development of calb2b expressing dI6 interneurons and motor neurons underlies locomotor defects observed in calretinin knock-down zebrafish larvae Dev. Biol. (IF 2.7) Pub Date : 2024-01-25 Ana Belen Iglesias Gonzalez, Harmen Kornelis Koning, Melek Umay Tuz-Sasik, Ilse van Osselen, Remy Manuel, Henrik Boije
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Distinct developmental patterns in Anopheles stephensi organ systems Dev. Biol. (IF 2.7) Pub Date : 2024-01-23 Khushboo Agrawal, Sunil Prabhakar, Baskar Bakthavachalu, Dhananjay Chaturvedi
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ARF6, a component of intercellular bridges, is essential for spermatogenesis in mice Dev. Biol. (IF 2.7) Pub Date : 2024-01-17 Hetty N. Wong, Tingfang Chen, P. Jeremy Wang, Lawrence B. Holzman
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Neuronal excitability modulates developmental time of Drosophila melanogaster Dev. Biol. (IF 2.7) Pub Date : 2024-01-14 Aidan P.C. Dermady, Dionna L. DeFazio, Emily M. Hensley, Daniel L. Ruiz, Alejandra D. Chavez, Sarah A. Iannone, Niall M. Dermady, Lexis V. Grandel, Alexis S. Hill
Developmental time is a fundamental life history trait that affects the reproductive success of animals. Developmental time is known to be regulated by many genes and environmental conditions, yet mechanistic understandings of how various cellular processes influence the developmental timing of an organism are lacking. The nervous system is known to control key processes that affect developmental time
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scRNA-seq analysis of cells comprising the amphioxus notochord Dev. Biol. (IF 2.7) Pub Date : 2024-01-14 Hiroki Takahashi, Kanako Hisata, Rin Iguchi, Sakura Kikuchi, Michio Ogasawara, Noriyuki Satoh
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Measuring transcription factor function with cell type-specific somatic transgenesis in chicken embryos Dev. Biol. (IF 2.7) Pub Date : 2024-01-11 Hui Zhu, Andrew J. Bendall
Retroviral-mediated misexpression in chicken embryos has been a powerful research tool for developmental biologists in the last two decades. In the retroviral vectors that are widely used for somatic transgenesis, a coding sequence of interest is under the transcriptional control of a strong viral promoter in the long terminal repeat. While this has proven to be effective for studying secreted signalling
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Fecundity is optimized by levels of nutrient signal-dependent expression of Dve and EcR in Drosophila male accessory gland Dev. Biol. (IF 2.7) Pub Date : 2024-01-08 Mirai Matsuka, Shinichi Otsune, Seiko Sugimori, Yasuhiro Tsugita, Hitoshi Ueda, Hideki Nakagoshi
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The avian ectodermal default competence to make feathers Dev. Biol. (IF 2.7) Pub Date : 2024-01-06 D, a, n, i, e, l, l, e, , D, h, o, u, a, i, l, l, y
Feathers originate as protofeathers before birds, in pterosaurs and basal dinosaurs. What characterizes a feather is not only its outgrowth, but its barb cells differentiation and a set of beta-corneous proteins. Reticula appear concomitantly with feathers, as small bumps on plantar skin, made only of keratins. Avian scales, with their own set of beta-corneous proteins, appear more recently than feathers
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Molecular aspects of regeneration in insects Dev. Biol. (IF 2.7) Pub Date : 2023-12-30 Shivali Pandita, Sanchita Singh, Sanjay Kumar Bajpai, Geetanjali Mishra, Gauri Saxena, Praveen C. Verma
Regeneration is a fascinating phenomenon observed in various organisms across the animal kingdom. Different orders of class Insecta are reported to possess comprehensive regeneration abilities. Several signalling molecules, such as morphogens, growth factors, and others trigger a cascade of events that promote wound healing, blastema formation, growth, and repatterning. Furthermore, epigenetic regulation
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Anp32e protects against accumulation of H2A.Z at Sox motif containing promoters during zebrafish gastrulation Dev. Biol. (IF 2.7) Pub Date : 2023-12-28 Fabian N. Halblander, Fanju W. Meng, Patrick J. Murphy
Epigenetic regulation of chromatin states is crucial for proper gene expression programs and progression during development, but precise mechanisms by which epigenetic factors influence differentiation remain poorly understood. Here we find that the histone variant H2A.Z accumulates at Sox motif-containing promoters during zebrafish gastrulation while neighboring genes become transcriptionally active
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Claudin-3 in the non-neural ectoderm is essential for neural fold fusion in chicken embryos Dev. Biol. (IF 2.7) Pub Date : 2023-12-27 Elizabeth-Ann Legere, Amanda I. Baumholtz, Jean-François Boisclair Lachance, Madison Archer, Jörg Piontek, Aimee K. Ryan
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Regenerative loss in the animal kingdom as viewed from the mouse digit tip and heart Dev. Biol. (IF 2.7) Pub Date : 2023-12-24 Fayth Hui Tan, Marianne E. Bronner
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The IRE1/Xbp1 axis restores ER and tissue homeostasis perturbed by excess Notch in Drosophila Dev. Biol. (IF 2.7) Pub Date : 2023-12-23 Yu Li, Dongyue Liu, Haochuan Wang, Xuejing Zhang, Bingwei Lu, Shuangxi Li
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Dgcr8 functions in the secondary heart field for outflow tract and right ventricle development in mammals Dev. Biol. (IF 2.7) Pub Date : 2023-12-17 Silvia E. Racedo, Yang Liu, Lijie Shi, Deyou Zheng, Bernice E. Morrow
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Mechanical stress can regulate temporomandibular joint cavitation via signalling pathways Dev. Biol. (IF 2.7) Pub Date : 2023-12-17 Yilin She, Rong Ren, Nan Jiang
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Meet the new Special Content Editor Dev. Biol. (IF 2.7) Pub Date : 2023-12-16 Sally A. Moody
Abstract not available
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DBFasTrac – Transfer your reviewed manuscript to DB for faster publication Dev. Biol. (IF 2.7) Pub Date : 2023-12-14 Ondine Cleaver
Abstract not available
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Preterm birth affects both surfactant synthesis and lung liquid resorption actors in fetal sheep Dev. Biol. (IF 2.7) Pub Date : 2023-12-09 Leona Orlandi, Yoann Rodriguez, Anne Leostic, Corinne Giraud, Maya-Laure Lang, François Vialard, Vincent Mauffré, Emmanuelle Motte-Signoret
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The development of thoracic and abdominal muscle depends on SDF1 and CXCR4 Dev. Biol. (IF 2.7) Pub Date : 2023-12-08 Imadeldin Yahya, Aisha Abduelmula, Dorit Hockman, Beate Brand-Saberi, Gabriela Morosan-Puopolo
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In vitro modeling of cranial placode differentiation: Recent advances, challenges, and perspectives Dev. Biol. (IF 2.7) Pub Date : 2023-12-03 Casey Griffin, Jean-Pierre Saint-Jeannet
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A CRISPR-Cas9-mediated versatile method for targeted integration of a fluorescent protein gene to visualize endogenous gene expression in Xenopus laevis Dev. Biol. (IF 2.7) Pub Date : 2023-12-03 Makoto Mochii, Kai Akizuki, Hero Ossaka, Norie Kagawa, Yoshihiko Umesono, Ken-ichi T. Suzuki
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SMPD3 expression is spatially regulated in the developing embryo by SOXE factors Dev. Biol. (IF 2.7) Pub Date : 2023-12-03 Michael L. Piacentino, Aria J. Fasse, Alexis Camacho-Avila, Ilya Grabylnikov, Marianne E. Bronner
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Fgf signalling is required for gill slit formation in the skate, Leucoraja erinacea Dev. Biol. (IF 2.7) Pub Date : 2023-11-29 Jenaid M. Rees, Michael A. Palmer, J. Andrew Gillis
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From soap bubbles to multicellular organisms: Unraveling the role of cell adhesion and physical constraints in tile pattern formation and tissue morphogenesis Dev. Biol. (IF 2.7) Pub Date : 2023-11-22 Hideru Togashi, Steven Ray Davis, Makoto Sato
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Mask exhibits trxG-like behavior and associates with H3K27ac marked chromatin Dev. Biol. (IF 2.7) Pub Date : 2023-11-18 Ammad Shaukat, Mahnoor Hussain Bakhtiari, Daim Shiraz Chaudhry, Muhammad Haider Farooq Khan, Jawad Akhtar, Ahmed Hassan Abro, Muhammad Abdul Haseeb, Aaminah Sarwar, Khalida Mazhar, Zain Umer, Muhammad Tariq
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Sox9 is associated with two distinct patterning events during snake lung morphogenesis Dev. Biol. (IF 2.7) Pub Date : 2023-11-22 Benjamin J. van Soldt, Brian D. Metscher, Michael K. Richardson, Wellington V. Cardoso
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Islet architecture in adult mice is actively maintained by Robo2 expression in β cells Dev. Biol. (IF 2.7) Pub Date : 2023-11-15 Bayley J. Waters, Zoe R. Birman, Matthew R. Wagner, Julia Lemanski, Barak Blum
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The ftz upstream element drives late ftz stripes but is not required for regulation of Ftz target genes Dev. Biol. (IF 2.7) Pub Date : 2023-11-15 Matthew D. Fischer, Patricia Graham, Leslie Pick
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Experimental validation and characterization of putative targets of Escargot and STAT, two master regulators of the intestinal stem cells in Drosophila melanogaster Dev. Biol. (IF 2.7) Pub Date : 2023-11-11 Armen Khanbabei, Lina Segura, Cynthia Petrossian, Aaron Lemus, Ithan Cano, Courtney Frazier, Armen Halajyan, Donnie Ca, Mariano Loza-Coll
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Myosin XV is a negative regulator of signaling filopodia during long-range lateral inhibition Dev. Biol. (IF 2.7) Pub Date : 2023-11-11 Rhiannon Clements, Tyler Smith, Luke Cowart, Jennifer Zhumi, Alan Sherrod, Aidan Cahill, Ginger L. Hunter
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Neurog1 and Olig2 integrate patterning and neurogenesis signals in development of zebrafish dopaminergic and glutamatergic dual transmitter neurons Dev. Biol. (IF 2.7) Pub Date : 2023-11-07 Christian Altbürger, Meta Rath, Daniel Armbruster, Wolfgang Driever
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The proneural factors Ascl1a and Ascl1b contribute to the terminal differentiation of dopaminergic GABAergic dual transmitter neurons in zebrafish Dev. Biol. (IF 2.7) Pub Date : 2023-11-04 Christian Altbürger, Meta Rath, Johanna Wehrle, Wolfgang Driever
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Evidence of interactions among apoptosis, cell proliferation, and dedifferentiation in the rudiment during whole-organ intestinal regeneration in the sea cucumber Dev. Biol. (IF 2.7) Pub Date : 2023-11-03 Josean Reyes-Rivera, Valentina Grillo-Alvarado, Ashley E. Soriano-López, José E. García-Arrarás
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Exploring the roles of noncoding RNAs in craniofacial abnormalities: A systematic review Dev. Biol. (IF 2.7) Pub Date : 2023-11-03 Cheng Shi, Pengfei Jiao, Zhiyi Chen, Lan Ma, Siyue Yao
Congenital craniofacial abnormalities are congenital anomalies of variable expressivity and severity with a recognizable set of abnormalities, which are derived from five identifiable primordial structures. They can occur unilaterally or bilaterally and include various malformations such as cleft lip with/without palate, craniosynostosis, and craniofacial microsomia. To date, the molecular etiology
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Global repression by tailless during segmentation Dev. Biol. (IF 2.7) Pub Date : 2023-10-24 Lauro Hiroshi Pimentel Masuda, Alan Utsuni Sabino, John Reinitz, Alexandre Ferreira Ramos, Ariane Machado-Lima, Luiz Paulo Andrioli
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Small molecule-mediated reprogramming of Xenopus blastula stem cells to a neural crest state Dev. Biol. (IF 2.7) Pub Date : 2023-10-25 Paul B. Huber, Carole LaBonne
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A robust knock-in approach using a minimal promoter and a minicircle Dev. Biol. (IF 2.7) Pub Date : 2023-10-14 Margaret Keating, Ryan Hagle, Daniel Osorio-Méndez, Anjelica Rodriguez-Parks, Sarah I. Almutawa, Junsu Kang