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Effects of Hypoxia and Reoxygenation on Metabolic Profiles of Cardiomyocytes Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-03-18 Luis Daniel Montañez Condori, Cristofher Victor Vivas, Yan Borges Barreto, Ligia Ferreira Gomes, Adriano Mesquita Alencar, Antonio Carlos Bloise
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Pharmacological Insights: Mitochondrial ROS Generation by FNC (Azvudine) in Dalton’s Lymphoma Cells Revealed by Super Resolution Imaging Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-03-14 Naveen Kumar, Vikram Delu, Ilya Ulasov, Sanjay Kumar, Rishi Kant Singh, Sandeep Kumar, Alok Shukla, Anand Kumar Patel, Lokesh Yadav, Ruchi Tiwari, Kumari Rachana, Shivashish Priyadarshi Mohanta, Varsha Singh, Anuradha Yadav, Kaushalendra Kaushalendra, Arbind Acharya
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Stabilin-2 mediated apoptotic cell phagocytosis induces interleukin-10 expression by p38 and Pbx1 signaling Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-03-13
Abstract Apoptotic cell death occurs under normal physiological conditions, such as development, tissue remodeling, and inflammation. Appropriate removal of apoptotic cells by phagocytes and the secretion of anti-inflammatory cytokines such as IL-10 are important mechanisms for maintaining tissue homeostasis. Apoptotic cell phagocytosis is mediated by several phosphatidylserine recognition receptors
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Oxidative Stress, Endoplasmic Reticulum Stress and Apoptosis in the Pathology of Alzheimer’s Disease Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-03-12 Bidemi Emmanuel Ekundayo, Tajudeen Olabisi Obafemi, Olusola Bolaji Adewale, Blessing Ariyo Obafemi, Babatunji Emmanuel Oyinloye, Stella Kemilola Ekundayo
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Role of sirtuin 1 (SIRT1) in regulation of autophagy and nuclear factor-kappa Beta (NF-ĸβ) pathways in sorafenib-resistant hepatocellular carcinoma (HCC) Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-03-11 Hui-Yin Chan, Thamil Selvee Ramasamy, Felicia Fei-Lei Chung, Sin-Yeang Teow
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FGF21 Inhibits Hypoxia/Reoxygenation-induced Renal Tubular Epithelial Cell Injury by Regulating the PPARγ/NF-κB Signaling Pathway Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-03-08 Ruixue Li, Xi Liu
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Melatonin Inhibits AGS Cell Proliferation by Binding to the ATP Binding Site of CDK2 Under Hyperglycemic Conditions Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-03-07 Abhishek Chatterjee, Tapasi Roy, Deeti Jyothi, Vineet Kumar Mishra, Umesh Prasad Singh, Snehasikta Swarnakar
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Dynamic alterations in M2 macrophage subtypes enhance flap expansion efficiency and tissue regeneration Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-03-05 Xiangyue Wang, Mingyu Zhao, Qianwen Wang, Jiaqi Wang, Tailing Wang
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Drp1: Focus on Diseases Triggered by the Mitochondrial Pathway Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-03-04 Fulin Sun, Min Fang, Huhu Zhang, Qinghang Song, Shuang Li, Ya Li, Shuyao Jiang, Lina Yang
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HMGA1 regulates the mitochondrial apoptosis pathway in sepsis-induced cardiomyopathy Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-03-02 Jing Xu, Xinwei Li, Qianqian Lu, Xiaohua Li, Hongying Shan
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Effect and Mechanism of Mycobacterium avium MAV-5183 on Apoptosis of Mouse Ana-1 Macrophages Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-03-02
Abstract To investigate the effects and mechanisms of Mycobacterium avium MAV-5183 protein on apoptosis in mouse Ana-1 macrophages. A pET-21a-MAV-5183 recombinant plasmid was constructed. The recombinant MAV-5183 protein was cloned, expressed, purified, and identified using an anti-His-tagged antibody. Rabbits were immunized to obtain antiserum, and its potency and immunoreactivity were assessed through
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DEAD Box RNA Helicases: Biochemical Properties, Role in RNA Processing and Ribosome Biogenesis Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-03-02 Ashaq Hussain
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Comparative modeling of fluorescence and P700 induction kinetics for alga Scenedesmus sp. obliques and cyanobacterium Synechocystis sp. PCC 6803. Role of state 2–state 1 transitions and redox state of plastoquinone pool Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-02-10
Abstract The model of thylakoid membrane system (T-M model) (Belyaeva et al. Photosynth Res 2019, 140:1–19) has been improved in order to analyze the induction data for dark-adapted samples of algal (Scenedesmus obliques) and cyanobacterial (Synechocystis sp. PCC 6803) cells. The fluorescence induction (FI) curves of Scenedesmus were measured at light exposures of 5 min, while FI and P700 redox transformations
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Marine Polysaccharides Carrageenans Enhance Eryptosis and Alter Lipid Order of Cell Membranes in Erythrocytes Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-02-09 Volodymyr Prokopiuk, Anatolii Onishchenko, Liliya Tryfonyuk, Yevgen Posokhov, Tetyana Gorbach, Yurii Kot, Kateryna Kot, Pavel Maksimchuk, Oksana Nakonechna, Anton Tkachenko
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Berberine ameliorates the progression of primary sclerosing cholangitis by activating farnesoid X receptor Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-02-08 Hassan Hameed, Nida Irshad, Muhammad Abrar Yousaf, Sidra Mumtaz, Imran Sohail
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E3 Ubiquitin Ligase ASB14 Inhibits Cardiomyocyte Proliferation by Regulating MAPRE2 Ubiquitination Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-02-06
Abstract The ubiquitin proteasome system is a highly specific and selective protein regulatory system that plays an essential role in the regulation of the cell cycle. Despite its significance, the role of ubiquitination in cardiomyocyte proliferation remains largely unclear. This study aimed to investigate the potential impact of E3 ubiquitin ligase ASB14 (Ankyrin Repeat And SOCS Box Containing 14)
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The Morphology and Ultrastructure of Dermal Telocytes Characterized by TEM and AFM Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-02-01
Abstract This investigation delves into the structural foundation of human dermal telocytes (TCs) with the aim of elucidating their role in signal transmission. Dermal TCs were isolated from human foreskins via enzymatic digestion and flow cytometric sorting, and identified by immunohistochemical staining with an antibody against CD34. The ultrastructure of TCs was examined using transmission electron
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Emerging Role of Extracellular Vesicles in Intercellular Communication in the Brain: Implications for Neurodegenerative Diseases and Therapeutics Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-02-01 Souhrid Sarkar, Somi Patranabis
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Correction: Lentivirus-Mediated Overexpression of SIVA-1 Reverses Cisplatin Resistance in Gastric Cancer in vitro Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-01-31 Xiao-Tong Wang, Lei Li, Fan-Biao Kong, Xiao-Gang Zhong, Wei Mai
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Complex Topology of Ubiquitin Chains Mediates Lysosomal Degradation of MrgC Proteins Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-01-30 Jiacheng Yu, Dan Li, Mingming Xie, Jun Xie, Zhen Wang, Xiaoping Gu, Zhengliang Ma, Yu’e Sun
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Gastrodin Suppresses the Progression of Atherosclerosis and Vascular Inflammation by Regulating TLR4/NF‐κB Pathway Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-01-25 Bing Dai, Cunfa Liu, Song Zhang, Mei Huang, Shugang Yin
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Alpha-lipoic Acid Prevents Bone Loss in Type 2 Diabetes and Postmenopausal Osteoporosis Coexisting Conditions by Modulating the YAP/Glut4 Pathway Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-01-23 Lei Xu, Chunfang Zhang, Jiawu Bao, Guozhu Han, Changyuan Wang, Yuanqing Cai, Gang Xu, Huijun Sun, Mozhen Liu
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FNC (4′-azido-2′-deoxy-2′-fluoro(arbino)cytidine) as an Effective Therapeutic Agent for NHL: ROS Generation, Cell Cycle Arrest, and Mitochondrial-Mediated Apoptosis Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-01-22
Abstract Cytotoxic nucleoside analogs (NAs) hold great promise in cancer therapeutics by mimicking endogenous nucleosides and interfering with crucial cellular processes. Here, we investigate the potential of the novel cytidine analog, 4′-azido-2′-deoxy-2′-fluoro(arbino)cytidine (FNC), as a therapeutic agent for Non-Hodgkin lymphoma (NHL) using Dalton’s lymphoma (DL) as a T-cell lymphoma model. FNC
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Adiponectin Receptor Agonist Effectively Suppresses Hepatocellular Carcinoma Growth Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-01-20 Mai Ly Thi Nguyen, Chi Pham, Van Tran Pham, Phuong Linh Thi Nham, Ba Thang Ta, Dinh Tuan Le, Quoc Vuong Le, Xuan Cuong Hoang, Przemyslaw Bozko, Linh Toan Nguyen, Khac Cuong Bui
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Exosomes Derived from hucMSCs Primed with IFN-γ Suppress the NF-κB Signal Pathway in LPS-Induced ALI by Modulating the miR-199b-5p/AFTPH Axis Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-01-13
Abstract Exosomes (exos) are primarily responsible for the process of mesenchymal stem cells (MSCs) treatment for acute lung injury (ALI), but the mechanism remains unclear, particularly in altered microenvironment. Therefore, this study aimed to investigate the potential mechanism of exos derived from human umbilical cord mesenchymal stem cells (hucMSCs) primed with interferon-gamma (IFN-γ) on ALI
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Investigating the Potential Mechanisms of Ferroptosis and Autophagy in the Pathogenesis of Gestational Diabetes Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-01-12 Xiaomei Lv, Jing Jiang, Yujun An
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DADS Inhibits the Proliferation of MDCC-MSB-1 Cells by Inducing Autophagy via the MEK/ERK Signalling Pathway Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-01-12 Yanying Pan, Jianying Liu, Dongliang Wang, Pengfei Zhou, Tao Chen, Yulong Tang, Chunxiao Ji
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Berberine and RNAi-Targeting Telomerase Reverse Transcriptase (TERT) and/or Telomerase RNA Component (TERC) Caused Oxidation in Colorectal Cancer Cell Line, HCT 116: An Integrative Approach using Molecular and Metabolomic Studies Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-01-10 Muhammad Azizan Samad, Mohd Zuwairi Saiman, Nazia Abdul Majid, Saiful Anuar Karsani, Jamilah Syafawati Yaacob
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Glycolytic enzymes in non-glycolytic web: functional analysis of the key players Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-01-09 Avirup Malla, Suvroma Gupta, Runa Sur
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Curcumin and Ferroptosis: a Promising Target for Disease Prevention and Treatment Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-01-06
Abstract Ferroptosis is a recently identified form of cell death characterized by iron accumulation and lipid peroxidation. Unlike apoptosis, necrosis, and autophagy, ferroptosis operates through a distinct molecular pathway. Curcumin, derived from turmeric rhizomes, is a natural compound with diverse therapeutic benefits, including neuroprotective, anti-metabolic syndrome, anti-inflammatory, and anti-cancer
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Chemotherapeutic and Antiproliferative Effect of Purified Protein from Marine Catfish Tachysurus Dussumieri on Human Colon Cancer Cell Line Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-01-06
Abstract The present study aimed to investigate the purified protein from the epidermal mucus of marine catfish Tachysurus dussumieri on the human colon cancer cell line. The bioactive protein was purified with the Anion exchange chromatography and the collected fractions were then tested to assess cell viability in HT 29 cells through the MTT assay. The most responding active purified protein fraction
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Multi-omics Analyses Reveal Function of Apolipoprotein E in Alternative Splicing and Tumor Immune Microenvironment in Kidney Renal Clear Cell Carcinoma via Pan-cancer Analysis Cell Biochem. Biophys. (IF 2.6) Pub Date : 2024-01-06
Abstract Apolipoprotein E (APOE) regulates lipid metabolism, associated with the development of various cancers. However, its precise prognostic significance and functions in alternative splicing and the tumor immune microenvironment remain unclear. In this study, we extracted APOE expression in pan-cancer from TCGA and analyzed mRNA transcriptome, cell lines, and protein levels. Furthermore, we analyzed
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Single-Cell Sequencing Technology and Its Application in the Study of Central Nervous System Diseases Cell Biochem. Biophys. (IF 2.6) Pub Date : 2023-12-22
Abstract The mammalian central nervous system consists of a large number of cells, which contain not only different types of neurons, but also a large number of glial cells, such as astrocytes, oligodendrocytes, and microglia. These cells are capable of performing highly refined electrophysiological activities and providing the brain with functions such as nutritional support, information transmission
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Tubulin Regulates Plasma Membrane Ca2+-ATPase Activity in a Lipid Environment-dependent Manner Cell Biochem. Biophys. (IF 2.6) Pub Date : 2023-12-22 Noelia E. Monesterolo, Verónica S. Santander, Alexis N. Campetelli, Juan F. Rivelli Antonelli, Ayelén D. Nigra, Melisa M. Balach, Tamara Muhlberger, Gabriela Previtali, César H. Casale
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Hypoxia Potentiated Lung Cancer Cell Migration and Invasion by up-regulating HIF1α/JAK2/STAT3 Axis and Activating MMP13 Transcription Cell Biochem. Biophys. (IF 2.6) Pub Date : 2023-12-21 Xiaoju Cheng, Damin Liang, Xiaoqian Li, Chengmin Deng, Meng Ye, Jiao Yang, Yurui Liu, Kaifeng Wu, Jie Wu, Peng Tian
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β-carotene inhibits MAPKs signaling pathways on rat colonic epithelial cells to attenuate TNF-α-induced intestinal inflammation and injury Cell Biochem. Biophys. (IF 2.6) Pub Date : 2023-12-11 Yang Song, Lingyu Zhu, Xin Zheng
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Cardioprotective Effect of 2-Ethyl-3-Hydroxy-6-Methylpyridinium 2-Nitroxysuccinate Against Adrenaline/Hydrocortisone-Induced Myocardial Ischemia in Mice: Modulation of Free-Radical Processes in Biomembranes and Monoamine Oxidase A Activity Cell Biochem. Biophys. (IF 2.6) Pub Date : 2023-12-08 Irina I. Faingold, Anastasia V. Smolina, Yulia V. Soldatova, Darya A. Poletaeva, Anastasia A. Balakina, Tatyana E. Sashenkova, Uguljan Yu. Allayarova, Tatyana R. Prikhodchenko, Svetlana V. Blokhina, Lyudmila A. Makartseva, David A. Areshidze, Vladislav N. Varfolomeev, Denis V. Mishchenko, Raisa A. Kotelnikova
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Understanding CFTR Functionality: A Comprehensive Review of Tests and Modulator Therapy in Cystic Fibrosis Cell Biochem. Biophys. (IF 2.6) Pub Date : 2023-12-04 Shorya Thakur, Ankita, Shubham Dash, Rupali Verma, Charanjit Kaur, Rajesh Kumar, Avijit Mazumder, Gurvinder Singh
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Evaluation of the Moonlighting Histone H3 Specific Protease (H3ase) Activity and the Dehydrogenase Activity of Glutamate Dehydrogenase (GDH) Cell Biochem. Biophys. (IF 2.6) Pub Date : 2023-12-01 Jogeswar Satchidananda Purohit, Madhulika Singh, Yashankita Raghuvanshi, Saima Syeda, Madan M. Chaturvedi
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Cholesterol Hydroperoxide Co-trafficking in Testosterone-generating Leydig Cells: GPx4 Inhibition of Cytotoxic and Anti-steroidogenic Effects Cell Biochem. Biophys. (IF 2.6) Pub Date : 2023-11-23 Pawel Pabisz, Jerzy Bazak, Michal Sabat, Albert W. Girotti, Witold Korytowski
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Editorial Expression of Concern: Induction of Human Bone Marrow Mesenchymal Stem Cells Differentiation into Neural-Like Cells Using Cerebrospinal Fluid. Cell Biochem. Biophys. (IF 2.6) Pub Date : 2023-12-01 Ying Ye,Yin-Ming Zeng,Mei-Rong Wan,Xian-Fu Lu
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New Perspective on the Interaction Behavior Between Riboflavin and β Lactoglobulin-β Casein Complex by Biophysical Techniques Cell Biochem. Biophys. (IF 2.6) Pub Date : 2023-11-17 Farzaneh Samandar, Sara Malek-Mohammadi, Zahra Aram, Farangis Rastin, Shakiba Tolou-Shikhzadeh-Yazdi, Zeinab Amiri-Tehranizadeh, Mohammad Reza Saberi, Jamshidkhan Chamani
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Peculiarities of Glucose Molecules Destruction under Irradiation at the M-30 Microtron (12.5 MeV): Mass Spectrometric Studies Cell Biochem. Biophys. (IF 2.6) Pub Date : 2023-11-15 V. T. Maslyuk, A. N. Zavilopulo, N. I. Svatiuk, Y. A. Bandurin
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An Intriguing Structural Modification in Neutrophil Migration Across Blood Vessels to Inflammatory Sites: Progress in the Core Mechanisms Cell Biochem. Biophys. (IF 2.6) Pub Date : 2023-11-14 Zexu Wang, Yufang Guo, Yulei Zhang, Liangquan Wu, Li Wang, Qiuqi Lin, Bing Wan
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Immune Features of Tumor Microenvironment: A Genetic Spotlight Cell Biochem. Biophys. (IF 2.6) Pub Date : 2023-10-23 Milad Asadi, Habib Zarredar, Venus Zafari, Zahra Soleimani, Hossein Saeedi, Ayse Caner, Dariush Shanehbandi
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Role of toll-like receptor in the pathogenesis of oral cancer Cell Biochem. Biophys. (IF 2.6) Pub Date : 2023-10-19 Ananya Bhardwaj, Divya Prasad, Sayali Mukherjee
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Ubiquitination Process Mediates Prostate Cancer Development and Metastasis through Multiple Mechanisms Cell Biochem. Biophys. (IF 2.6) Pub Date : 2023-10-17 Wen Li, Zhiyu Wang
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Mitigation of the Deleterious Effect of Heavy Metals on the Conformational Stability of Ubiquitin through Osmoprotectants Cell Biochem. Biophys. (IF 2.6) Pub Date : 2023-10-16 Khadega Khamis Moh Alazoumi, Pradakshina Sharma, Asimul Islam, Humaira Farooqi
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Avocado Paste Phenolics Mitigate a High-Fat Diet-Induced Plasma HDL Decrease in Male Wistar Rats, by Altering the mRNA Expression of Hepatic SCARB1 Cell Biochem. Biophys. (IF 2.6) Pub Date : 2023-10-13 J. Abraham Domínguez-Avila, Norma J. Salazar-López, Marcelino Montiel-Herrera, Diana A. Corella-Salazar, Joaquín Rodrigo-Garcia, Humberto Astiazaran-Garcia, Mónica A. Villegas-Ochoa, Gustavo A. González-Aguilar
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Exploring Different Ultrasonic Parameters and Treatment Conditions to Optimize In Vitro Sonodynamic Therapeutic Effects in Cancer Cells Cell Biochem. Biophys. (IF 2.6) Pub Date : 2023-10-13 Yilin Zheng, Jun Wang, Haijun Chen, Yu Gao
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Circular RNA circ-SLC7A5 Functions as a Competing Endogenous RNA to Impact Cell Biological Behaviors in Esophageal Squamous Cell Carcinoma (ESCC) Cell Biochem. Biophys. (IF 2.6) Pub Date : 2023-10-09 Lei Wang, Zhipeng Hong
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Matrix Stiffness Regulated Endoplasmic Reticulum Stress-mediated Apoptosis of Osteosarcoma Cell through Ras Signal Cascades Cell Biochem. Biophys. (IF 2.6) Pub Date : 2023-10-03 Huan Deng, Xuedong Shu, Yao Wang, Junwei Zhang, Yue Yin, Fang Wu, Jing He
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LAMB3 Promotes Myofibrogenesis and Cytoskeletal Reorganization in Endometrial Stromal Cells via the RhoA/ROCK1/MYL9 Pathway Cell Biochem. Biophys. (IF 2.6) Pub Date : 2023-10-06 Xiaomei Qin, Bin Zeng, Suren R. Sooranna, Mujun Li
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Fatty Acids and their Proteins in Adipose Tissue Inflammation Cell Biochem. Biophys. (IF 2.6) Pub Date : 2023-10-04 Rahul Mallick, Sanjay Basak, Ranjit K. Das, Antara Banerjee, Sujay Paul, Surajit Pathak, Asim K. Duttaroy
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Interface between Resolvins and Efferocytosis in Health and Disease Cell Biochem. Biophys. (IF 2.6) Pub Date : 2023-10-04 Fatemeh Mohammad-Rafiei, Samira Negahdari, Zahra Tahershamsi, Seyed Mohammad Gheibihayat
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The Prognosis of Cancer Depends on the Interplay of Autophagy, Apoptosis, and Anoikis within the Tumor Microenvironment Cell Biochem. Biophys. (IF 2.6) Pub Date : 2023-10-03 Shweta Gulia, Prakash Chandra, Asmita Das
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Pyroptosis Inhibition in Disease Treatment: Opportunities and Challenges Cell Biochem. Biophys. (IF 2.6) Pub Date : 2023-10-02 Navya Bandharam, Richard F. Lockey, Narasaiah Kolliputi
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SIRT3 Regulates the ROS-FPR1/HIF-1α Axis under Hypoxic Conditions to Influence Lung Cancer Progression Cell Biochem. Biophys. (IF 2.6) Pub Date : 2023-09-25 Bo Huang, Jie Ding, HongRong Guo, HongJuan Wang, JianQun Xu, Quan Zheng, LiJun Zhou
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Impact of Interdependent Ca2+ and IP3 Dynamics On ATP Regulation in A Fibroblast Model Cell Biochem. Biophys. (IF 2.6) Pub Date : 2023-09-25 Ankit Kothiya, Neeru Adlakha
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Activation of Wnt Pathway Suppresses Growth of MUG-Chor1 Chordoma Cell Line Cell Biochem. Biophys. (IF 2.6) Pub Date : 2023-09-26 Hatice Burcu Şişli, Taha Bartu Hayal, Selinay Şenkal, Ezgi Bulut, Binnur Kıratlı, Ayla Burçin Asutay, Fikrettin Şahin, Ömer Faruk Bayrak, Ayşegül Doğan