Cell Prolif., 2018, 44, 234–243 In vitro study of enhanced osteogenesis induced by HIF‐1a‐transduced bone marrow stem cells D. Zou1, W. Han2, S. You3, D. Ye4, L. Wang3, S. Wang1, J. Zhao4, W. Zhang4, X. Jiang4, X. Zhang4, Y. Huang3 1School of Stomatology, Tongji University, Shanghai, China 2Department of Oral and Maxillofacial Surgery, Nanjing Stomatological Hospital, Nanjing, China 3Department of

To the Editor, Acute lung injury (ALI) and the inflammatory cytokine storm cause considerable amount of deaths in the COVID‐19 pandemic.1, 2 Currently, very limited therapeutic options are available for the COVID‐19‐induced ALI. In our preclinical experiments,3 we found that a single intravenous transfusion of immunity‐ and matrix‐regulatory cells (IMRCs), derived from fully differentiated human embryonic

To the Editor: Pulmonary fibrosis is a severe complication in COVID‐19 patients. Based on our previous success with stem cell therapy of acute lung injury in mouse models and 2 COVID‐19 patients in a pilot compassionate use study,1 we describe a Phase 1 clinical trial where we treated COVID‐19 patients with pulmonary fibrosis using human embryonic stem cell–derived immunity‐ and matrix‐regulatory cells

The 2019 coronavirus disease (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has become a global pandemic. Until 13 September 2020, SARS‐CoV‐2 caused more than twenty eight million infections and nine hundred thousand deaths worldwide. SARS‐CoV‐2 uses angiotensin‐converting enzyme 2 (ACE2) for cell entry into various lung cells including endothelial cells and alveolar

Upon entry into the lungs, SARS‐CoV‐2 uses the angiotensin‐converting enzyme 2 (ACE2) receptor to facilitate viral entry into the epithelial cells that cover the airways and the alveolar gas‐exchanging space, leading to extensive epithelial injury, which contributes to local inflammatory storm and a series of respiratory syndromes.1 A number of drugs, based on their modes of action, have been suggested

During the COVID‐19 pandemic, in addition to the pandemic itself, a phenomenon called an ‘infodemic’—defined by the World Health Organization as the spread of misleading information on the pandemic—has also gained attention. In the field of stem cell research, researchers and regulators have been fighting against false and misleading information, particularly advertisements for unproven and unauthorized

‘Requirements for Human Embryonic Stem Cells’ is the first set of guidelines on human embryonic stem cells in China, jointly drafted and agreed upon by experts from the Chinese Society for Stem Cell Research. This standard specifies the technical requirements, test methods, test regulations, instructions for use, labelling requirements, packaging requirements, storage requirements and transportation

The standard ‘General requirements for stem cells’ is the first set of general guidelines for stem cell research and production in China, jointly drafted and agreed upon by experts from the Chinese Society for Stem Cell Research. This standard specifies the classification, ethical requirements, quality requirements, quality control requirements, detection control requirements and waste disposal requirements