-
Circadian Variation in the Response to Vaccination: A Systematic Review and Evidence Appraisal J. Biol. Rhythms (IF 3.5) Pub Date : 2024-03-09 Cathy A. Wyse, Laura M. Rudderham, Enya A. Nordon, Louise M. Ince, Andrew N. Coogan, Lorna M. Lopez
Molecular timing mechanisms known as circadian clocks drive endogenous 24-h rhythmicity in most physiological functions, including innate and adaptive immunity. Consequently, the response to immune challenge such as vaccination might depend on the time of day of exposure. This study assessed whether the time of day of vaccination (TODV) is associated with the subsequent immune and clinical response
-
Divergent Circadian Foraging Strategies in Response to Diurnal Predation Versus Persistent Rain in Asian Weaver Ant, Oecophylla smaragdina, Suggest Possible Energetic Trade-offs J. Biol. Rhythms (IF 3.5) Pub Date : 2024-03-09 Avishek Dolai, Severine Soltani, Benjamin Smarr, Amlan Das
The study of chronobiology of foraging behavior in social insects offers valuable models for the investigation of circadian rhythms. We scored hourly nest entries and exits of Oecophylla smaragdina (Asian weaver ant) workers in 9 active non-polydomous nests on days with and without rain and with and without a primarily diurnal predator present. After determining that Oecophylla display a high nest
-
Association Between Augmentation Index and Total Sleep Time in Night Shift Workers J. Biol. Rhythms (IF 3.5) Pub Date : 2024-03-04 Waléria D. P. Gusmão, Victor M. Silva, Annelise M. G. Paiva, Marco Antonio Mota-Gomes, Wilson Nadruz, Claudia R. C. Moreno
Augmentation index and pulse wave velocity are markers of vascular compromise and independent predictors of cardiovascular risk and mortality. While the link between shift work and heightened cardiovascular risk is established, the intricate genesis of early cardiovascular outcomes in shift workers remains incompletely understood. However, there is evidence that sleep duration plays a role in this
-
Using Polygenic Scores for Circadian Rhythms to Predict Wellbeing, Depressive Symptoms, Chronotype, and Health J. Biol. Rhythms (IF 3.5) Pub Date : 2024-03-01 Anne Landvreugd, René Pool, Michel G. Nivard, Meike Bartels
The association between circadian rhythms and diseases has been well established, while the association with mental health is less explored. Given the heritable nature of circadian rhythms, this study aimed to investigate the relationship between genes underlying circadian rhythms and mental health outcomes, as well as a possible gene-environment correlation for circadian rhythms. Polygenic scores
-
One Health: Circadian Medicine Benefits Both Non-human Animals and Humans Alike J. Biol. Rhythms (IF 3.5) Pub Date : 2024-02-21 Hesham I. Farag, Barbara A. Murphy, James R. Templeman, Charlene Hanlon, Jessica Joshua, Thomas G. Koch, Lee Niel, Anna K. Shoveller, Gregoy Y. Bedecarrats, Amy Ellison, David Wilcockson, Tami A. Martino
Circadian biology’s impact on human physical health and its role in disease development and progression is widely recognized. The forefront of circadian rhythm research now focuses on translational applications to clinical medicine, aiming to enhance disease diagnosis, prognosis, and treatment responses. However, the field of circadian medicine has predominantly concentrated on human healthcare, neglecting
-
The Suprachiasmatic Nucleus at 50: Looking Back, Then Looking Forward J. Biol. Rhythms (IF 3.5) Pub Date : 2024-02-17 Daisuke Ono, David R. Weaver, Michael H. Hastings, Ken-Ichi Honma, Sato Honma, Rae Silver
It has been 50 years since the suprachiasmatic nucleus (SCN) was first identified as the central circadian clock and 25 years since the last overview of developments in the field was published in the Journal of Biological Rhythms. Here, we explore new mechanisms and concepts that have emerged in the subsequent 25 years. Since 1997, methodological developments, such as luminescent and fluorescent reporter
-
Investigating the Roles for Essential Genes in the Regulation of the Circadian Clock in Synechococcus elongatus Using CRISPR Interference J. Biol. Rhythms (IF 3.5) Pub Date : 2024-02-15 Nouneh Boodaghian, Hyunsook Park, Susan E. Cohen
Circadian rhythms are found widely throughout nature where cyanobacteria are the simplest organisms, in which the molecular details of the clock have been elucidated. Circadian rhythmicity in cyanobacteria is carried out via the KaiA, KaiB, and KaiC core oscillator proteins that keep ~24 h time. A series of input and output proteins—CikA, SasA, and RpaA—regulate the clock by sensing environmental changes
-
The Impact of Pupil Constriction on the Relationship Between Melanopic EDI and Melatonin Suppression in Young Adult Males J. Biol. Rhythms (IF 3.5) Pub Date : 2024-02-13 Isabel Schöllhorn, Oliver Stefani, Robert J. Lucas, Manuel Spitschan, Christian Epple, Christian Cajochen
The pupil modulates the amount of light that reaches the retina. Not only luminance but also the spectral distribution defines the pupil size. Previous research has identified steady-state pupil size and melatonin attenuation to be predominantly driven by melanopsin, which is expressed by a unique subgroup of intrinsically photosensitive retinal ganglion cells (ipRGCs) that are sensitive to short-wavelength
-
Mathematical Analysis of Light-sensitivity Related Challenges in Assessment of the Intrinsic Period of the Human Circadian Pacemaker J. Biol. Rhythms (IF 3.5) Pub Date : 2024-02-06 Imran M. Usmani, Derk-Jan Dijk, Anne C. Skeldon
Accurate assessment of the intrinsic period of the human circadian pacemaker is essential for a quantitative understanding of how our circadian rhythms are synchronized to exposure to natural and man-made light-dark (LD) cycles. The gold standard method for assessing intrinsic period in humans is forced desynchrony (FD) which assumes that the confounding effect of lights-on assessment of intrinsic
-
Circadian Rhythms in Skin Barrier Function in Atopic Dermatitis: A Pilot Study J. Biol. Rhythms (IF 3.5) Pub Date : 2024-02-02 Marta Iwanaszko, Nathan Waldeck, Ron Anafi, Amy S. Paller, Phyllis C. Zee, Anna B. Fishbein
Atopic dermatitis (AD) is symptomatically worse in the evening, but the mechanism driving nocturnal eczema remains elusive. Our objective was to determine the circadian rhythm of skin barrier function measured by transepidermal water loss (TEWL) in AD patients and explore the molecular underpinnings. A pilot study was performed on a diverse group of AD ( n = 4) and control ( n = 2) young patients.
-
Evaluating the Adaptive Fitness of Circadian Clocks and their Evolution J. Biol. Rhythms (IF 3.5) Pub Date : 2024-01-08 Maria Luísa Jabbur, Chitrang Dani, Kamiel Spoelstra, Antony N. Dodd, Carl Hirschie Johnson
Surely most chronobiologists believe circadian clocks are an adaptation of organisms that enhances fitness, but are we certain that this focus of our research effort really confers a fitness advantage? What is the evidence, and how do we evaluate it? What are the best criteria? These questions are the topic of this review. In addition, we will discuss selective pressures that might have led to the
-
The Negative Effects of Travel on Student Athletes Through Sleep and Circadian Disruption. J. Biol. Rhythms (IF 3.5) Pub Date : 2023-11-18 H Craig Heller,Erik Herzog,Allison Brager,Gina Poe,Ravi Allada,Frank Scheer,Mary Carskadon,Horacio O de la Iglesia,Rockelle Jang,Ashley Montero,Kenneth Wright,Philippe Mouraine,Matthew P Walker,Namni Goel,John Hogenesch,Russell N Van Gelder,Lance Kriegsfeld,Cheri Mah,Christopher Colwell,Jamie Zeitzer,Michael Grandner,Chandra L Jackson,J Roxanne Prichard,Steve A Kay,Ketema Paul
Collegiate athletes must satisfy the academic obligations common to all undergraduates, but they have the additional structural and social stressors of extensive practice time, competition schedules, and frequent travel away from their home campus. Clearly such stressors can have negative impacts on both their academic and athletic performances as well as on their health. These concerns are made more
-
Characterizing Gun Violence by Time, Day of the Week, Holidays, and Month in 6 US Cities, 2015-2021. J. Biol. Rhythms (IF 3.5) Pub Date : 2023-11-18 Elizabeth B Klerman,Mahmoud Affouf,Rebecca Robbins,Jay M Iyer,Cornelia Griggs,Peter T Masiakos,Chana A Sacks
Developing interventions to prevent firearm-related violence and to address its consequences requires an improved understanding of when these violent events are most likely to occur. We explored gunshot events in 6 of the most populated cities in the United States by time of day, day of week, holiday/non-holiday, and month using publicly available datasets. In some of these cities, gunshot events occurred
-
The Molecular Circadian Clock Is a Target of Anti-cancer Translation Inhibitors. J. Biol. Rhythms (IF 3.5) Pub Date : 2023-10-23 Alexandre Berthier,Céline Gheeraert,Manuel Johanns,Manjula Vinod,Bart Staels,Jérôme Eeckhoute,Philippe Lefebvre
Circadian-paced biological processes are key to physiology and required for metabolic, immunologic, and cardiovascular homeostasis. Core circadian clock components are transcription factors whose half-life is precisely regulated, thereby controlling the intrinsic cellular circadian clock. Genetic disruption of molecular clock components generally leads to marked pathological events phenotypically affecting
-
Use of Light Protection Equipment at Night Reduces Time Until Discharge From the Neonatal Intensive Care Unit: A Randomized Interventional Study. J. Biol. Rhythms (IF 3.5) Pub Date : 2023-10-17 Ana Carolina Odebrecht Vergne de Abreu,Melissa Alves Braga de Oliveira,Tamila Alquati,André Comiran Tonon,Mariana de Novaes Reis,Augusto Camargo Rossi,Fernanda Sbaraini Bonatto,Maria Paz Hidalgo
Newborn infants' circadian systems are not completely developed and rely on external temporal cues for synchronizing their biological rhythms to the environment. In neonatal intensive care units (NICUs), lighting is usually continuous or irregular and infants are exposed to artificial light at night, which can have negative health consequences. Therefore, the aim of this study was to evaluate the impact
-
The Daily Patterns of Emergency Medical Events. J. Biol. Rhythms (IF 3.5) Pub Date : 2023-10-02 Mary E Helander,Margaret K Formica,Dessa K Bergen-Cico
This study examines population-level daily patterns of time-stamped emergency medical service (EMS) dispatches to establish their situational predictability. Using visualization, sinusoidal regression, and statistical tests to compare empirical cumulative distributions, we analyzed 311,848,450 emergency medical call records from the US National Emergency Medical Services Information System (NEMSIS)
-
Comments on Block et al., Pittendrigh Remembered, 2023. J. Biol. Rhythms (IF 3.5) Pub Date : 2023-09-30 Benjamin Rusak
-
Are We Finding Functional or Merely Statistically Significant Rhythms? J. Biol. Rhythms (IF 3.5) Pub Date : 2023-08-23 Bharath Ananthasubramaniam
-
Ambient Temperature Effects on the Spring and Autumn Somatic Growth Trajectory Show Plasticity in the Photoneuroendocrine Response Pathway in the Tundra Vole. J. Biol. Rhythms (IF 3.5) Pub Date : 2023-08-11 Mattis Jayme van Dalum,Laura van Rosmalen,Daniel Appenroth,Fernando Cazarez Marquez,Renzo T M Roodenrijs,Lauren de Wit,Roelof A Hut,David G Hazlerigg
Seasonal mammals register photoperiodic changes through the photoneuroendocrine system enabling them to time seasonal changes in growth, metabolism, and reproduction. To a varying extent, proximate environmental factors like ambient temperature (Ta) modulate timing of seasonal changes in physiology, conferring adaptive flexibility. While the molecular photoneuroendocrine pathway governing the seasonal
-
Vasculature of the Suprachiasmatic Nucleus: Pathways for Diffusible Output Signals. J. Biol. Rhythms (IF 3.5) Pub Date : 2023-08-08 Yifan Yao,Isabella K Green,Alana B Taub,Ruya Tazebay,Joseph LeSauter,Rae Silver
Transplant studies demonstrate unequivocally that the suprachiasmatic nucleus (SCN) produces diffusible signals that can sustain circadian locomotor rhythms. There is a vascular portal pathway between the SCN and the organum vasculosum of the lamina terminalis in mouse brain. Portal pathways enable low concentrations of neurosecretions to reach specialized local targets without dilution in the systemic
-
Chronotype and Affective Response to Sleep Restriction and Subsequent Sleep Deprivation. J. Biol. Rhythms (IF 3.5) Pub Date : 2023-08-04 Rebecca C Cox,Hannah K Ritchie,Oliver A Knauer,Molly K Guerin,Ellen R Stothard,Kenneth P Wright
Prior research indicates that sleep restriction, sleep deprivation, and circadian misalignment diminish positive affect, whereas effects on negative affect are inconsistent. One potential factor that may influence an individual's affective response to sleep restriction, sleep deprivation, and circadian misalignment is chronotype. Later chronotypes generally report higher negative affect and lower positive
-
The SCN-HPA-Periphery Circadian Timing System: Mathematical Modeling of Clock Synchronization and the Effects of Photoperiod on Jetlag Adaptation. J. Biol. Rhythms (IF 3.5) Pub Date : 2023-08-02 Yannuo Li,Ioannis P Androulakis
Synchronizing the circadian timing system (CTS) to external light/dark cycles is crucial for homeostasis maintenance and environmental adaptation. The CTS is organized hierarchically, with the central pacemaker located in the suprachiasmatic nuclei (SCN) generating coherent oscillations that are entrained to light/dark cycles. These oscillations regulate the release of glucocorticoids by the hypot
-
Roles for the Synechococcus elongatus RNA-Binding Protein Rbp2 in Regulating the Circadian Clock. J. Biol. Rhythms (IF 3.5) Pub Date : 2023-07-28 Briana M McKnight,Shannon Kang,Tam H Le,Mingxu Fang,Genelyn Carbonel,Esbeydi Rodriguez,Sutharsan Govindarajan,Nitsan Albocher-Kedem,Amanda L Tran,Nicholas R Duncan,Orna Amster-Choder,Susan S Golden,Susan E Cohen
The cyanobacterial circadian oscillator, consisting of KaiA, KaiB, and KaiC proteins, drives global rhythms of gene expression and compaction of the chromosome and regulates the timing of cell division and natural transformation. While the KaiABC posttranslational oscillator can be reconstituted in vitro, the Kai-based oscillator is subject to several layers of regulation in vivo. Specifically, the
-
Connecting the Dots: Potential Interactions Between Sex Hormones and the Circadian System During Memory Consolidation. J. Biol. Rhythms (IF 3.5) Pub Date : 2023-07-19 Hannah M Boyd,Karyn M Frick,Janine L Kwapis
Both the circadian clock and sex hormone signaling can strongly influence brain function, yet little is known about how these 2 powerful modulatory systems might interact during complex neural processes like memory consolidation. Individually, the molecular components and action of each of these systems have been fairly well-characterized, but there is a fundamental lack of information about how these
-
Modeling the Effects of Napping and Non-napping Patterns of Light Exposure on the Human Circadian Oscillator. J. Biol. Rhythms (IF 3.5) Pub Date : 2023-07-10 Shelby R Stowe,Monique K LeBourgeois,Cecilia Diniz Behn
In early childhood, consolidation of sleep from a biphasic to a monophasic sleep-wake pattern, that is, the transition from sleeping during an afternoon nap and at night to sleeping only during the night, represents a major developmental milestone. Reduced napping behavior is associated with an advance in the timing of the circadian system; however, it is unknown if this advance represents a standard
-
Meta-analysis of Diurnal Transcriptomics in Mouse Liver Reveals Low Repeatability of Rhythm Analyses. J. Biol. Rhythms (IF 3.5) Pub Date : 2023-06-29 Thomas G Brooks,Aditi Manjrekar,Antonijo Mrcˇela,Gregory R Grant
To assess the consistency of biological rhythms across studies, 57 public mouse liver tissue timeseries totaling 1096 RNA-seq samples were obtained and analyzed. Only the control groups of each study were included, to create comparable data. Technical factors in RNA-seq library preparation were the largest contributors to transcriptome-level differences, beyond biological or experiment-specific factors
-
Impact of Simulated Rotating Shift Work on Mammary Tumor Development in the p53R270H©/+WAPCre Mouse Model for Breast Cancer. J. Biol. Rhythms (IF 3.5) Pub Date : 2023-06-26 Astrid A Streng,Kirsten C G Van Dycke,Conny T M van Oostrom,Daniela C F Salvatori,Gerben Hulsegge,Inês Chaves,Till Roenneberg,Serge A L Zander,Harry van Steeg,Gijsbertus T J van der Horst,Linda W M van Kerkhof
Epidemiological studies associate night shift work with increased breast cancer risk. However, the underlying mechanisms are not clearly understood. To better understand these mechanisms, animal models that mimic the human situation of different aspects of shift work are needed. In this study, we used "timed sleep restriction" (TSR) cages to simulate clockwise and counterclockwise rotating shift work
-
Circadian Regulation of the Neuroimmune Environment Across the Lifespan: From Brain Development to Aging. J. Biol. Rhythms (IF 3.5) Pub Date : 2023-06-26 Ruizhuo Chen,Brandy N Routh,Andrew D Gaudet,Laura K Fonken
Circadian clocks confer 24-h periodicity to biological systems, to ultimately maximize energy efficiency and promote survival in a world with regular environmental light cycles. In mammals, circadian rhythms regulate myriad physiological functions, including the immune, endocrine, and central nervous systems. Within the central nervous system, specialized glial cells such as astrocytes and microglia
-
Impact of Light Schedules and Model Parameters on the Circadian Outcomes of Individuals. J. Biol. Rhythms (IF 3.5) Pub Date : 2023-06-23 Caleb Mayer,Olivia Walch,Daniel B Forger,Kevin Hannay
Key differences exist between individuals in terms of certain circadian-related parameters, such as intrinsic period and sensitivity to light. These variations can differentially impact circadian timing, leading to challenges in accurately implementing time-sensitive interventions. In this work, we parse out these effects by investigating the impact of parameters from a macroscopic model of human circadian
-
Chronotype, Social Jetlag, and Nicotine Use. J. Biol. Rhythms (IF 3.5) Pub Date : 2023-06-21 Neda Ghotbi,Andrea Rabenstein,Luísa K Pilz,Tobias Rüther,Till Roenneberg
Late chronotype, which often leads to higher social jetlag (SJL), is strongly associated with the prevalence of smoking. Any circadian disruption, strain, or misalignment, results in people not being able to live according to their biological time as is described by SJL, which we will therefore use as umbrella term. We hypothesized two scenarios potentially explaining the association between smoking
-
Reduced Plasticity in Coupling Strength in the Aging SCN Clock as Revealed by Kuramoto Modeling. J. Biol. Rhythms (IF 3.5) Pub Date : 2023-06-16 Anouk W van Beurden,Janusz M Meylahn,Stefan Achterhof,Renate Buijink,Anneke Olde Engberink,Stephan Michel,Johanna H Meijer,Jos H T Rohling
The mammalian circadian clock is located in the suprachiasmatic nucleus (SCN) and consists of a network of coupled neurons, which are entrained to the environmental light-dark cycle. The phase coherence of the neurons is plastic and driven by the duration of daylight. With aging, the capacity to behaviorally adapt to seasonal changes in photoperiod reduces. The mechanisms underlying photoperiodic adaptation
-
Estradiol Regulates Circadian Responses to Acute and Constant Light Exposure in Female Mice. J. Biol. Rhythms (IF 3.5) Pub Date : 2023-06-06 Julie M Michaud,Caitlin T Waring,Fernanda Medeiros Contini,Meredith E Burns,John C Price,Janessa Quintana,Holly A Concepcion,Hannah V Deane,Joseph A Seggio
Sex hormones are well known to modulate circadian timekeeping as well as the behavioral and physiological responses to circadian disruption. Gonadectomy, reducing the amount of circulating gonadal hormones, in males and females produces alterations to the free-running rhythm and the responses to light exposure by the central oscillator of the suprachiasmatic nucleus (SCN). In this study, we tested
-
Sensitive Timing: A Reappraisal of Chronobiology's Foundational Texts. J. Biol. Rhythms (IF 3.5) Pub Date : 2023-05-25 Patrick Emery,André Klarsfeld,Ralf Stanewsky,Orie T Shafer
The origin of experimental chronobiology can be traced to observations made in the 18th and 19th centuries on the sensitive plant Mimosa, which were described in two seminal reports: Jean-Jacques d'Ortous de Mairan's "Observation Botanique" (A Botanical Observation) and Augustin Pyramus de Candolle's "Du sommeil des feuilles" (On the sleep of leaves). Both report observations of the striking daily
-
Molecular and Neural Mechanisms of Temperature Preference Rhythm in Drosophila melanogaster. J. Biol. Rhythms (IF 3.5) Pub Date : 2023-05-24 Tadahiro Goda,Yujiro Umezaki,Fumika N Hamada
Temperature influences animal physiology and behavior. Animals must set an appropriate body temperature to maintain homeostasis and maximize survival. Mammals set their body temperatures using metabolic and behavioral strategies. The daily fluctuation in body temperature is called the body temperature rhythm (BTR). For example, human body temperature increases during wakefulness and decreases during
-
S-Cone Photoreceptors Regulate Daily Rhythms and Light-Induced Arousal/Wakefulness in Diurnal Grass Rats (Arvicanthis niloticus). J. Biol. Rhythms (IF 3.5) Pub Date : 2023-05-24 Antony B Kim,Emma M Beaver,Stephen G Collins,Lance J Kriegsfeld,Steven W Lockley,Kwoon Y Wong,Lily Yan
Beyond visual perception, light has non-image-forming effects mediated by melanopsin-expressing, intrinsically photosensitive retinal ganglion cells (ipRGCs). The present study first used multielectrode array recordings to show that in a diurnal rodent, Nile grass rats (Arvicanthis niloticus), ipRGCs generate rod/cone-driven and melanopsin-based photoresponses that stably encode irradiance. Subsequently
-
A Cannabinoid Receptor 1 Agonist Reduces Light-induced Phase Delays in Male But Not Female Mice J. Biol. Rhythms (IF 3.5) Pub Date : 2023-05-15 Timothy D. Niepokny, Eric M. Mintz
Animals adapt to a changing environment by synchronizing their circadian rhythms to different stimuli, the strongest and most reliable being the daily light-dark cycle. Photic information reaches t...
-
A Subset of Circadian Neurons Expressing dTRPA1 Enables Appropriate Phasing of Activity Rhythms in Drosophila melanogaster Under Warm Temperatures J. Biol. Rhythms (IF 3.5) Pub Date : 2023-04-27 Aishwariya Srikala Iyengar, Sushma Rao, Vasu Sheeba
Under conditions of prolonged durations of warmth, flies counter potential temperature stress by shifting their locomotor activity from day into night when the conditions are likely to be less hars...
-
Patricia J. DeCoursey (28 December 1932 to 1 January 2022). J. Biol. Rhythms (IF 3.5) Pub Date : 2023-04-18 Mary Harrington,Joseph S Takahashi
-
Persistence of Nocturnality in Decapitated and Bisected Flatworms J. Biol. Rhythms (IF 3.5) Pub Date : 2023-03-24 Shauni E. T. Omond, John A. Lesku
The ability of flatworms to regenerate entire brain structures, and indeed much of their body from mere fragments of the whole animal, presents the unique opportunity to observe the development of ...
-
Temporal Dissociation Between Activity and Body Temperature Rhythms of a Subterranean Rodent (Ctenomys famosus) in Field Enclosures J. Biol. Rhythms (IF 3.5) Pub Date : 2023-03-16 Milene G. Jannetti, Patricia Tachinardi, Veronica S. Valentinuzzi, Gisele A. Oda
Several wild rodents, such as the subterranean tuco-tucos (Ctenomys famosus), switch their time of activity from diurnal to nocturnal when they are transferred from field to the laboratory. Neverth...
-
Antisense Transcription of the Neurospora Frequency Gene Is Rhythmically Regulated by CSP-1 Repressor but Dispensable for Clock Function J. Biol. Rhythms (IF 3.5) Pub Date : 2023-03-01 Ibrahim A. Cemel, Axel C. R. Diernfellner, Michael Brunner
The circadian clock of Neurospora crassa is based on a negative transcriptional/translational feedback loops. The frequency (frq) gene controls the morning-specific rhythmic transcription of a sens...
-
Associations Between Multidimensional Sleep Health Parameters and Adolescents’ Self-reported Light Exposure in the Free-living Environment J. Biol. Rhythms (IF 3.5) Pub Date : 2023-02-26 Gabrielle Gauthier-Gagné, Sujata Saha, Jana Jensen, Gail Sommerville, Reut Gruber
The objective of this study was to characterize the associations between light exposure in the free-living environment and multiple dimensions of sleep health of typically developing adolescents. F...
-
Voluntary Wheel Running Exercise Does Not Attenuate Circadian and Cardiac Dysfunction Caused by Conditional Deletion of Bmal1 J. Biol. Rhythms (IF 3.5) Pub Date : 2023-02-20 Musharraf Yusifova, Aykhan Yusifov, Sydney M. Polson, William D. Todd, Emily E. Schmitt, Danielle R. Bruns
Circadian misalignment occurs with age, jet lag, and shift work, leading to maladaptive health outcomes including cardiovascular diseases. Despite the strong link between circadian disruption and h...
-
Diurnal Changes in Capecitabine Clock-Controlled Metabolism Enzymes Are Responsible for Its Pharmacokinetics in Male Mice J. Biol. Rhythms (IF 3.5) Pub Date : 2023-02-10 Yasemin Kubra Akyel, Dilek Ozturk Civelek, Narin Ozturk Seyhan, Seref Gul, Isil Gazioglu, Zeliha Pala Kara, Francis Lévi, Ibrahim Halil Kavakli, Alper Okyar
The circadian timing system controls absorption, distribution, metabolism, and elimination processes of drug pharmacokinetics over a 24-h period. Exposure of target tissues to the active form of th...
-
Modern Language for Modern Circadian Biologists: The End of the "Slave" Oscillator. J. Biol. Rhythms (IF 3.5) Pub Date : 2023-02-15 Casey-Tyler Berezin
-
Prolonged Light Exposure Induces Circadian Impairment in Aquaporin-4-Knockout Mice J. Biol. Rhythms (IF 3.5) Pub Date : 2023-01-24 Atsumi Murakami, Kouki Tsuji, Minako Isoda, Masahiro Matsuo, Yoichiro Abe, Masato Yasui, Hitoshi Okamura, Keiko Tominaga
Astrocytes are densely present in the suprachiasmatic nucleus (SCN), which is the master circadian oscillator in mammals, and are presumed to play a key role in circadian oscillation. However, spec...
-
Caenorhabditis elegans as a Promising Model Organism in Chronobiology J. Biol. Rhythms (IF 3.5) Pub Date : 2023-01-21 María Laura Migliori, María Eugenia Goya, Melisa Luciana Lamberti, Francisco Silva, Rosana Rota, Claire Bénard, Diego Andrés Golombek
Circadian rhythms represent an adaptive feature, ubiquitously found in nature, which grants living beings the ability to anticipate daily variations in their environment. They have been found in a ...
-
School Attendance, Chronotype, and Day-of-the-Week Effect in Adolescent Male Basketball Players J. Biol. Rhythms (IF 3.5) Pub Date : 2023-01-21 Simone Bruno, Davide Benedetti, Andrea Bazzani, Francesca Ferri, Iacopo Granieri, Francy Cruz-Sanabria, Simona Fiori, Paola d’Ascanio, Paolo Frumento, Ugo Faraguna
Adolescents’ conflict between circadian rhythm and early school start time is more pronounced in evening chronotypes, who tend to reduce sleep duration during school days compensating during the fr...
-
Validation of the Self-Rating of Biological Rhythm Disorder for Adolescents (SBRDA) Scale by Dim Light Melatonin Onset in Healthy Young Adults J. Biol. Rhythms (IF 3.5) Pub Date : 2023-01-12 Yang Xie, Xiaoyan Wu, Xingyue Mou, Meng Wang, Shuman Tao, Yuhui Wan, Fangbiao Tao
Understanding the biological rhythms that influence young adult health is vital because the combination of biological changes and a circadian phase delay lead to young adults being at high risk of ...
-
Chronic Alcohol Consumption Disrupts the Skeletal Muscle Circadian Clock in Female Mice J. Biol. Rhythms (IF 3.5) Pub Date : 2022-12-29 Abigail L. Tice, Joseph A. Laudato, Bradley S. Gordon, Jennifer L. Steiner
The intrinsic skeletal muscle core clock has emerged as a key feature of metabolic control and influences several aspects of muscle physiology. Acute alcohol intoxication disrupts the core molecula...
-
From Bench to Bedside and Back Again: Translating Circadian Science to Medicine. J. Biol. Rhythms (IF 3.5) Pub Date : 2022-12-30 Elizabeth B Klerman,Achim Kramer,Phyllis C Zee
-
Inducible Reporter Lines for Tissue-specific Monitoring of Drosophila Circadian Clock Transcriptional Activity J. Biol. Rhythms (IF 3.5) Pub Date : 2022-12-10 Lilyan M. Mather, Meghan E. Cholak, Connor M. Morfoot, Katherine C. Curro, Jacob Love, Daniel J. Cavanaugh
Organisms track time of day through the function of cell-autonomous molecular clocks. In addition to a central clock located in the brain, molecular clocks are present in most peripheral tissues. C...
-
An External Coincidence Model for the Lunar Cycle Reveals Circadian Phase-Dependent Moonlight Effects on Coral Spawning J. Biol. Rhythms (IF 3.5) Pub Date : 2022-12-02 Hideyuki Komoto, Che-Hung Lin, Yoko Nozawa, Akiko Satake
Many marine organisms synchronously spawn at specific times to ensure the success of external fertilization in the ocean. Corals are famous examples of synchronized spawning at specific lunar phase...
-
Sex Inclusion in Transcriptome Studies of Daily Rhythms J. Biol. Rhythms (IF 3.5) Pub Date : 2022-11-23 Dora Obodo, Elliot H. Outland, Jacob J. Hughey
Biomedical research on mammals has traditionally neglected females, raising the concern that some scientific findings may generalize poorly to half the population. Although this lack of sex inclusi...
-
Cross-sectional and Prospective Associations of Rest-Activity Rhythms With Body Mass Index in Older Men: A Novel Analysis Using Harmonic Hidden Markov Models J. Biol. Rhythms (IF 3.5) Pub Date : 2022-11-23 Brian Heckler, Miryoung Lee, Katie Stone, Cici Bauer, Qian Xiao
Growing evidence supports a role for rest-activity rhythms (RARs) in metabolic health. Epidemiological studies in adolescents and young adults showed that RAR characteristics consistent with weaken...
-
Evening Light Intensity and Phase Delay of the Circadian Clock in Early Childhood J. Biol. Rhythms (IF 3.5) Pub Date : 2022-11-22 Lauren E. Hartstein, Cecilia Diniz Behn, Kenneth P. Wright, Jr., Lameese D. Akacem, Shelby R. Stowe, Monique K. LeBourgeois
Late sleep timing is prevalent in early childhood and a risk factor for poor behavioral and health outcomes. Sleep timing is influenced by the phase of the circadian clock, with later circadian tim...
-
Modified Wavelet Analyses Permit Quantification of Dynamic Interactions Between Ultradian and Circadian Rhythms J. Biol. Rhythms (IF 3.5) Pub Date : 2022-11-15 Jonathan P. Riggle, Leslie M. Kay, Kenneth G. Onishi, David T. Falk, Benjamin L. Smarr, Irving Zucker, Brian J. Prendergast
Circadian rhythms provide daily temporal structure to cellular and organismal biological processes, ranging from gene expression to cognition. Higher-frequency (intradaily) ultradian rhythms are si...
-
Chronotype in Patients With Immune-Mediated Inflammatory Disease: A Systematic Review J. Biol. Rhythms (IF 3.5) Pub Date : 2022-11-14 Thomas D. Butler, Aala Mohammed Ali, Julie E. Gibbs, John T. McLaughlin
Immune-mediated inflammatory diseases (IMIDs) such as rheumatoid arthritis, inflammatory bowel disease, and asthma share common pathophysiological pathways characterized by chronic inflammation and...
-
The Association of Time of Day of ChAdOx1 nCoV-19 Vaccine Administration With SARS-CoV-2 Anti-Spike IgG Antibody Levels: An Exploratory Observational Study J. Biol. Rhythms (IF 3.5) Pub Date : 2022-11-11 Astrid C. Erber, Angelika Wagner, Marianna Karachaliou, Maren Jeleff, Polyxeni Kalafatis, Manolis Kogevinas, Beata Pepłońska, Isabel Santonja, Eva Schernhammer, Hannes Stockinger, Kurt Straif, Ursula Wiedermann, Thomas Waldhör, Kyriaki Papantoniou
Data from human and animal studies are highly suggestive of an influence of time of day of vaccine administration on host immune responses. In this population-based study, we aimed to investigate t...
-
Light on Shedding: A Review of Sex and Menstrual Cycle Differences in the Physiological Effects of Light in Humans J. Biol. Rhythms (IF 3.5) Pub Date : 2022-11-11 Parisa Vidafar, Manuel Spitschan
The human circadian system responds to light as low as 30 photopic lux. Furthermore, recent evidence shows that there are huge individual differences in light sensitivity, which may help to explain...