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Therapeutic proteins: developments, progress, challenges, and future perspectives 3 Biotech (IF 2.8) Pub Date : 2024-03-18 Vimal Kumar, Arti Barwal, Nitin Sharma, Danish Shafi Mir, Pradeep Kumar, Vikas Kumar
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A review on pharmacological studies of natural flavanone: pinobanksin 3 Biotech (IF 2.8) Pub Date : 2024-03-13 Brindha Elangovan
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Isolation and characterization of novel bioplasticizers from rose (Rosa damascena Mill.) petals and its suitability investigation for poly (butylene adipate-co-terephthalate) biofilm applications 3 Biotech (IF 2.8) Pub Date : 2024-03-12 Naushad Edayadulla, Divya Divakaran, Shanmuga Sundari Chandraraj, Indran Suyambulingam, Elammaran Jayamani, M. R. Sanjay, Suchart Siengchin
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Draft genome sequence of 'Candidatus Phytoplasma asteris,’ strain SW86 associated with sandal spike disease (SSD) 3 Biotech (IF 2.8) Pub Date : 2024-03-11 Kiran Kirdat, Bhavesh Tiwarekar, K. N. Manjula, S. Padma, Shivaji Sathe, R. Sundararaj, Amit Yadav
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Ab initio modeling of human IRS1 protein to find novel target to dock with drug MH to mitigate T2DM diabetes by insulin signaling 3 Biotech (IF 2.8) Pub Date : 2024-03-11 Ritika Kumari Singh, Avinash Kumar Chaurasiya, Arvind Kumar
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Isolation and molecular characterization of multidrug‑resistant Escherichia coli from chicken meat 3 Biotech (IF 2.8) Pub Date : 2024-03-10 Anugya Jaiswal, Aquib Khan, Akanksha Yogi, Sweta Singh, Arun Kumar Pal, Ramendra Soni, Pooja Tripathi, Jonathan A. Lal, Vijay Tripathi
Antibiotics in animal farms play a significant role in the proliferation and spread of antibiotic-resistant genes (ARGs) and antibiotic-resistant bacteria (ARB). The dissemination of antibiotic resistance from animal facilities to the nearby environment has become an emerging concern. The present study was focused on the isolation and molecular identification of Escherichia coli (E. coli) isolates
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An insight into the diagnostic, prognostic, and taxanes resistance of double zinc finger and homeodomain factor’s expression in naïve prostate cancer 3 Biotech (IF 2.8) Pub Date : 2024-03-10
Abstract Currently, clinical biomarkers are urgently needed to improve patient management to guide personal therapy for cancer. In this study, we investigate the deregulation of Zeb-1 in prostate cancer (PC) Tunisian patients. Expression patterns of the Zeb-1 were investigated in prostate adenocarcinoma and benign prostate biopsies using quantitative real-time reverse transcription-polymerase chain
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Characterizations of Ganoderma species causing basal stem rot disease in coconut tree 3 Biotech (IF 2.8) Pub Date : 2024-03-08 Umesh Sajjan, Manjunath Hubballi, Abhay K. Pandey, V. Devappa, H. P. Maheswarappa
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Anti-listerial peptides from a marine Bacillus velezensis FTL7: production optimization, characterizations and molecular docking studies 3 Biotech (IF 2.8) Pub Date : 2024-03-08
Abstract Antimicrobial peptides (AMPs) with potent anti-listerial activity were characterized from a novel marine Bacillus velezensis FTL7. A Box-Behnken statistical experimental design was used to study the combined impact of culture conditions on the production of AMPs by B. velezensis FTL7. The conditions optimized by statistical experimental design were 34.5 °C incubation temperature, 23 h incubation
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Mechanism of salt tolerance in the endangered semi-mangrove plant Barringtonia racemosa: anatomical structure and photosynthetic and fluorescence characteristics 3 Biotech (IF 2.8) Pub Date : 2024-03-08 Ju Hu, Xu Deng, Caihong Bai, Lin Li, Xiuling Yang, Chunxiao Lan, Haiyan Zhong, Xiaohui Tan, Fang Liang
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Intestinal microbial diversity of swines fed with different sources of lithium 3 Biotech (IF 2.8) Pub Date : 2024-03-06
Abstract A drug that is widely used in the treatment of psychiatric disorder is lithium (Li) salts. The people who make therapeutic use of this drug develop a series of side effects. Through metataxonomic data, this study assessed the impacts of lithium, as Li carbonate or Li-enriched mushrooms, on the microbial composition of the ileum, colon, and feces of piglets. Employing Bray–Curtis metric, no
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Protective effect of Pterospermum rubiginosum bark extract on bone mineral density and bone remodelling in estrogen deficient ovariectomized Sprague–Dawley (SD) rats 3 Biotech (IF 2.8) Pub Date : 2024-03-06
Abstract Osteoporosis is a common metabolic old age disorder characterised by low bone mass content (BMC) and mineral density (BMD) with micro-architectural deterioration of the extracellular matrix, further increasing bone fragility risk. Several traditional remedies, including plant extracts and herbal formulations, are used worldwide by local healers to improve the overall bone health and metabolism
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Preventive effect of Cleome spinosa against cucumber Fusarium wilt and improvement on cucumber growth and physiology 3 Biotech (IF 2.8) Pub Date : 2024-03-05 Xingzhe Zhang, Xianghai Meng, Xiaodan Jiao, Rina Sa, Zhen Wang, Jiwen Li, Baicheng Wang, Dong Liu, Bing Yang, Chunlei Zou, Yanju Zhang
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In silico investigation of potential phytoconstituents against ligand- and voltage-gated ion channels as antiepileptic agents 3 Biotech (IF 2.8) Pub Date : 2024-03-05 Punam Salaria, N. N. Subrahmanyeswara Rao, Tejas M. Dhameliya, M. Amarendar Reddy
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Diversity and functional characteristics of culturable bacterial endosymbionts from cassava whitefly biotype Asia II-5, Bemisia tabaci 3 Biotech (IF 2.8) Pub Date : 2024-03-05
Abstract Whitefly Bemisia tabaci, a carrier of cassava mosaic disease (CMD), poses a significant threat to cassava crops. Investigating culturable bacteria and their impact on whiteflies is crucial due to their vital role in whitefly fitness and survival. The whitefly biotype associated with cassava and transmitting CMD in India has been identified as Asia II 5 through partial mitochondrial cytochrome
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Heat shock protein paradigms in cancer progression: future therapeutic perspectives 3 Biotech (IF 2.8) Pub Date : 2024-03-05 Y. Mohammed Tausif, Dithu Thekkekkara, Thummuru Ekshita Sai, Vaishnavi Jahagirdar, H. R. Arjun, S. K. Meheronnisha, Amrita Babu, Aniruddha Banerjee
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Evaluation of immunomodulatory (humoral as well as cell-mediated) and cytokines (TNF-α & IL-10) regulating potential of Neolamarckia cadamba fruit extract in Wistar albino rats 3 Biotech (IF 2.8) Pub Date : 2024-03-05 Tarubala Sharma, Vishal Khandelwal
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Revisiting microbial exopolysaccharides: a biocompatible and sustainable polymeric material for multifaceted biomedical applications 3 Biotech (IF 2.8) Pub Date : 2024-03-04 Neelakanta Sarvashiva Kiran, Chandrashekar Yashaswini, Sudarshan Singh, Bhupendra Gopalbhai Prajapati
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Biological properties of caffeine, (+)-catechin, and theobromine: an in silico study 3 Biotech (IF 2.8) Pub Date : 2024-03-03 Nara Saraiva Dutra, Camila Medianeira da Silva D’Ávila, Thayline Correia da Silva, Tallys de Oliveira Mendes, Isadora Cassel Livinalli, Ana Clara Zanini Bertoncelli, Fernanda Krapf Saccol, Francine Carla Cadoná
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Optimized decolorization of two poly azo dyes Sirius Red and Sirius Blue using laccase-mediator system 3 Biotech (IF 2.8) Pub Date : 2024-03-01 Jihen Benali, Imen Ben Atitallah, Bouthaina Ghariani, Tahar Mechichi, Bilel Hadrich, Héla Zouari-Mechichi
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Antioxidant polysaccharide-enriched fractions obtained from olive leaves by ultrasound-assisted extraction with α-amylase inhibition, and antiproliferative activities 3 Biotech (IF 2.8) Pub Date : 2024-02-27 Rania Elayeb, Alejandra Bermúdez-Oria, Houda Lazreg Aref, Hatem Majdoub, Christos Ritzoulis, Alberto Mannu, Didier Le Cerf, Massimo Carraro, Sami Achour, Juan Fernández-Bolaños, Maher Trigui
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Microbial community dynamics and functional potentials in the conversion of oil palm wastes into biomethane 3 Biotech (IF 2.8) Pub Date : 2024-02-26 Hui Jing Ng, Kian Mau Goh, Adibah Yahya, Mohd Firdaus Abdul-Wahab
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Exploring genetic divergence and marker-trait associations for leaffolder Cnaphalocrocis medinalis (Guenee) resistance in rice landraces 3 Biotech (IF 2.8) Pub Date : 2024-02-25 Anjan Kumar Nayak, Prasanthi Golive, Arundhati Sasmal, B. N. Devanna, C. Anilkumar, Arup Kumar Mukherjee, Soumya Shephalika Dash, Shyamaranjan Das Mohapatra, Hatanath Subudhi
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Performance of Metarhizium rileyi Nm017: nutritional supplementation to improve production and quality conidia 3 Biotech (IF 2.8) Pub Date : 2024-02-24 Cindy Mejía, Jaime Rocha, Johanna Sanabria, Martha Isabel Gómez-Álvarez, Ginna Quiroga-Cubides
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Adenine’s impact on mice’s gut and kidney varies with the dosage administered and relates to intestinal microorganisms and enzyme activities 3 Biotech (IF 2.8) Pub Date : 2024-02-22 Mengsi Zhou, Xiaoya Li, Jin Liu, Yi Wu, Zhoujin Tan, Na Deng
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Autophagy: a necessary evil in cancer and inflammation 3 Biotech (IF 2.8) Pub Date : 2024-02-20
Abstract Autophagy, a highly regulated cellular process, assumes a dual role in the context of cancer. On the one hand, it functions as a crucial homeostatic pathway, responsible for degrading malfunctioning molecules and organelles, thereby maintaining cellular health. On the other hand, its involvement in cancer development and regression is multifaceted, contingent upon a myriad of factors. This
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Genome-wide analysis of cellulose synthase gene superfamily in Tectona grandis L.f. 3 Biotech (IF 2.8) Pub Date : 2024-02-19 Swathi Balakrishnan, Reshma Bhasker, Yasodha Ramasamy, Suma Arun Dev
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Enhancing (2S)-naringenin production in Saccharomyces cerevisiae by high-throughput screening method based on ARTP mutagenesis 3 Biotech (IF 2.8) Pub Date : 2024-02-18 Qian Gao, Song Gao, Weizhu Zeng, Jianghua Li, Jingwen Zhou
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Optimization of fungal chitosan production from Cunninghamella echinulata using statistical designs 3 Biotech (IF 2.8) Pub Date : 2024-02-18 Bhoomika M. Karamchandani, Priya A. Maurya, Manik Awale, Sunil G. Dalvi, Ibrahim M. Banat, Surekha K. Satpute
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circ_UTRN inhibits ferroptosis of ARJ21 cells to attenuate acute pancreatitis progression by regulating the miR-760-3p/FOXO1/GPX4 axis 3 Biotech (IF 2.8) Pub Date : 2024-02-18 Lanlan Wei, Bowen Li, Jing Long, Yanping Fu, Bin Feng
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Discovery of novel anticancer flavonoids as potential HDAC2 inhibitors: virtual screening approach based on molecular docking, DFT and molecular dynamics simulations studies 3 Biotech (IF 2.8) Pub Date : 2024-02-18
Abstract Virtual screening of a library of 329 flavonoids obtained from the NPACT database was performed to find out potential novel HDAC2 inhibitors. Eleven out of 329 selected flavonoids were screened based on molecular docking studies, as they have higher binding affinities than the standard drugs vorinostat and panobinostat. All screened compounds occupying the catalytic site of HDAC2 showed important
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Genome-wide runs of homozygosity signatures in diverse Indian goat breeds 3 Biotech (IF 2.8) Pub Date : 2024-02-17 Dibyasha Kar, Indrajit Ganguly, Sanjeev Singh, Avnish Kumar Bhatia, S. P. Dixit
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Phytol from Scoparia dulcis prevents NF-κB-mediated inflammatory responses during macrophage polarization 3 Biotech (IF 2.8) Pub Date : 2024-02-17 Parimalanandhini Duraisamy, Annapoorani Angusamy, Sangeetha Ravi, Mahalakshmi Krishnan, Livya Catherene Martin, Beulaja Manikandan, Janarthanan Sundaram, Manikandan Ramar
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Diversity of soil fungi from sacred groves of Kerala, India revealed by comparative metagenomics analysis using illumina sequencing 3 Biotech (IF 2.8) Pub Date : 2024-02-16
Abstract The diversity, composition, and abundance of soil fungi from three sacred groves in Kerala, namely Iringole kavu of Ernakulam District, Kollakal Thapovanam of Alappuzha District, and Poyilkavu of Kozhikode District were analysed using Metagenomics analysis and Illumina sequencing. A total of 30,584, 78,323, and 55,640 reads were obtained from these groves, respectively. Ascomycota constitutes
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Cardiovascular risk factors and carotid intima-media thickness with neurocognitive dysfunction in people living with HIV on stable combination anti-retroviral therapy 3 Biotech (IF 2.8) Pub Date : 2024-02-15
Abstract The goal of this clinical research was to determine the relationship between carotid intima-media thickness (cIMT), cardiovascular risk factors, and neuro-cognitive function in people living with HIV (PLHIV) and were on stable combination anti-retroviral therapy (cART). This is a cross-sectional study performed at a single center, including 149 patients who visited the anti-retroviral therapy
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Co-production of lipases and biosurfactants by Bacillus methylotrophicus in solid-state fermentation 3 Biotech (IF 2.8) Pub Date : 2024-02-15 Naiara Elisa Kreling, Victória Dutra Fagundes, Viviane Simon, Luciane Maria Colla
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Synergistic anti-diabetic effect of phloroglucinol and total procyanidin dimer isolated from Vitis vinifera methanolic seed extract potentiates via suppressing oxidative stress: in-vitro evaluation studies 3 Biotech (IF 2.8) Pub Date : 2024-02-14
Abstract Diabetes is often associated with increased oxidative stress caused by an imbalance between detoxification and ROS production. Unfortunately, many commercial drugs available today for treating this disease have adverse side effects and ultimately fail to restore glucose homeostasis. Therefore, finding a dietary anti-diabetic remedy that is safe, effective, and economical is crucial. In this
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Double Philadelphia chromosome: a rare and sole abnormality in pediatric B-acute lymphoblastic leukemia 3 Biotech (IF 2.8) Pub Date : 2024-02-14 Amritha Padmakumar, Priyakumari Thankamony, Jayasudha Arundhathi Vasudevan, Preethi Gopinath, Vineetha Radhakrishnan Chandraprabha, Akhila Raj Thampirajan Vimala Devi, Geetha Raj John Anitha, Mahitha Mohanan Sreelatha, Devipriya Padmakumar, Hariharan Sreedharan
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Purification, characterization of laccase from Pleurotus ostreatus HK35, and optimization for congo red biodecolorization using Box–Behnken design 3 Biotech (IF 2.8) Pub Date : 2024-02-14 Jantiya Isanapong, Kittikarn Suwannoi, Surangkana Lertlattanapong, Shweta Panchal
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Temporary immersion systems induce photomixotrophism during in vitro propagation of agave Tobalá 3 Biotech (IF 2.8) Pub Date : 2024-02-14 Eucario Mancilla-Álvarez, José Luis Spinoso-Castillo, Sandra Silvana Schettino-Salomón, Jericó Jabín Bello-Bello
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Exploration of potential hit compounds targeting 1-deoxy-d-xylulose 5-phosphate reductoisomerase (IspC) from Acinetobacter baumannii: an in silico investigation 3 Biotech (IF 2.8) Pub Date : 2024-02-13 Mahrukh Parveez Zia, Monika Jain, Jayaraman Muthukumaran, Amit Kumar Singh
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Alleviation of water-deficit stress in turmeric plant (Curcuma longa L.) using phosphate solubilizing rhizo-microbes inoculation 3 Biotech (IF 2.8) Pub Date : 2024-02-13 Daonapa Chungloo, Rujira Tisarum, Umpawa Pinruan, Thanyaporn Sotesaritkul, Kewalee Saimi, Patchara Praseartkul, Sushil Kumar Himanshu, Avishek Datta, Suriyan Cha-Um
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Natural variability and heritability of root-nodulation traits in chickpea (Cicer arietinum L.) minicore 3 Biotech (IF 2.8) Pub Date : 2024-02-13 Renu Verma, P. S. Shanmugavadivel, Naveen Kumar Arora, Murugesan Senthilkumar
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Natural flavonoids as potential therapeutics in the management of Alzheimer’s disease: a review 3 Biotech (IF 2.8) Pub Date : 2024-02-13 Phuong-Trang Nguyen-Thi, Tuong Kha Vo, Thi Hong Trang Pham, Thuy Trang Nguyen, Giau Van Vo
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Design, synthesis, molecular docking and pharmacological evaluation of some thiadiazole based nipecotic acid derivatives as a potential anticonvulsant and antidepressant agents 3 Biotech (IF 2.8) Pub Date : 2024-02-13 Gireesh Kumar Singh, Bindu Kumari, Nirupam Das, Kamaruz Zaman, Pratibha Prasad, Ravi Bhushan Singh
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Monkeypox virus: insights into pathogenesis and laboratory testing methods 3 Biotech (IF 2.8) Pub Date : 2024-02-12 Anoop Kumar, Neeraj Singh, Anupkumar R. Anvikar, Gauri Misra
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Exploring gender-based diversity for phenolic and organic acid profiles in the genetic resource of betel vine (Piper betle L.) from India as revealed through high-performance liquid chromatography (HPLC–DAD) 3 Biotech (IF 2.8) Pub Date : 2024-02-11
Abstract Betel vine (Piper betle L.) is a dioecious plant and has paved way for researchers to explore the available genetic resources for the biochemical compounds. In the study, twenty sexually dimorphic genotypes of betel vine were characterized for bio-compounds using high-performance liquid chromatography (HPLC–DAD), and as a result identified phenolic compounds and organic acids, including caffeic
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Potential of biosynthesized titanium dioxide nanoparticles towards wastewater treatment and antimicrobial activity 3 Biotech (IF 2.8) Pub Date : 2024-02-11 Malvika Mehta, Indu Bhushan
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Molecular authentication, metabolite profiling and in silico–in vitro cytotoxicity screening of endophytic Penicillium ramusculum from Withania somnifera for breast cancer therapeutics 3 Biotech (IF 2.8) Pub Date : 2024-02-09 Sherin Varghese, M. S. Jisha, K. C. Rajeshkumar, Virendra Gajbhiye, Niladri Haldar, Aazam Shaikh
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Exploration of bioactive compounds from Olea dioica in Western Ghats of Karnataka using GC–MS 3 Biotech (IF 2.8) Pub Date : 2024-02-08
Abstract Bioactive compounds in plants are essential for the formation of novel chemotherapeutic drugs, which have been used in Ayurveda to treat a variety of illnesses. Indian medicinal herbs have been used for thousands of years to treat a variety of illnesses, such as fever, cancer, snake bites, rheumatism, skin problems, and neurodegenerative diseases. GC–MS was used to locate and categorize bioactive
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TaqMan-based real-time polymerase chain reaction for the detection of feline chaphamaparvovirus 3 Biotech (IF 2.8) Pub Date : 2024-02-07
Abstract Feline chaphamaparvovirus (FeChPV) is a new viral strain detected in Chinese Mainland in recent years. The symptoms mainly include diarrhea and bloody stool in young cats, which can lead to death in severe cases. In this study, a TaqMan-based real-time quantitative PCR (qPCR) with specific primers and TaqMan probes based on the VP1 gene sequence of FeChPV was performed to detect the virus
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GABA synthesizing lactic acid bacteria and genomic analysis of Levilactobacillus brevis LAB6 3 Biotech (IF 2.8) Pub Date : 2024-02-07 Tushar Matta, Ruchika Bhatia, Santa Ram Joshi, Mahendra Bishnoi, Kanwaljit Chopra, Kanthi Kiran Kondepudi
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Probing the microbial diversity and probiotic candidates from Pakistani foods: isolation, characterization, and functional profiling 3 Biotech (IF 2.8) Pub Date : 2024-02-03 Amer Mumtaz, Ahmad Ali, Rehana Batool, Amina F. Mughal, Nazir Ahmad, Zainab Batool, Saira Abbas, Nauman Khalid, Iftikhar Ahmed
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Physicochemical cell disruption of Bacillus sp. for recovery of polyhydroxyalkanoates: future bioplastic for sustainability 3 Biotech (IF 2.8) Pub Date : 2024-02-02 G. Sohani Bhat, B. K. Deekshitha, V. Thivaharan, M. S. Divyashree
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Characterization of Sclerotium rolfsii causing foot rot: a severe threat of betel vine cultivation in Bangladesh 3 Biotech (IF 2.8) Pub Date : 2024-01-30
Abstract The development of the foot rot disease caused by the fungus Sclerotium rolfsii is one of the primary variables endangering betel vine production in Bangladesh. Consequently, with the ultimate objective of finding efficient preventive and control strategies for this infamous phytopathogen, the current study was undertaken for comprehensive population structure analysis, exploration of physiological
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Advances in functional lipid nanoparticles: from drug delivery platforms to clinical applications 3 Biotech (IF 2.8) Pub Date : 2024-01-29 Manikandan Dhayalan, Wei Wang, S. U. Mohammed Riyaz, Rakshi Anuja Dinesh, Jayashree Shanmugam, Santiagu Stephen Irudayaraj, Antony Stalin, Jayant Giri, Saurav Mallik, Ruifeng Hu
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Molecular tagging of seed size using MITE markers in an induced large seed mutant with higher cotyledon cell size in groundnut 3 Biotech (IF 2.8) Pub Date : 2024-01-29 Poonam Gajanan Bhad, Suvendu Mondal, Anand M. Badigannavar
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Unique footprints of balancing selection in bovine genome 3 Biotech (IF 2.8) Pub Date : 2024-01-26 Sonali Sonejita Nayak, Manjit Panigrahi, Divya Rajawat, Karan Jain, Anurodh Sharma, Bharat Bhushan, Triveni Dutt
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Cloning, expression, and characterization of a novel thermo-acidophilic l-asparaginase of Pseudomonas aeruginosa CSPS4 3 Biotech (IF 2.8) Pub Date : 2024-01-24 Vinay Kumar, Ravi Kumar, Shilpa Sharma, Arunim Shah, Chandra Prakash Chaturvedi, Digvijay Verma
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Morphometric and genetic characterization of cultured and wild populations of tilapia, Oreochromis niloticus in India 3 Biotech (IF 2.8) Pub Date : 2024-01-23 Charles Koffi Boussou, Sofia P. Das, Mausumee Mohanty, Gargee Das, Dhananjay K. Verma, Lakshman Sahoo, Padmanava Routray, Paramananda Das