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Assessment of antioxidant, anticancer, and antibacterial activities of the rhizome of ginger (Zingiber officinale) J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2024-01-26 Akram A. Alfuraydi, Ibrahim M. Aziz, Fahad N. Almajhdi
Background Zingiber officinale rhizome is rich in phenolic and flavonoids contributing antioxidant and anticancer activity. Methods This study was designed to assess the in vitro antioxidant, anticancer, and antibacterial activities of Z. officinale rhizome. Ethanol extract of Z. officinale rhizome was tested for total phenolic and flavonoid content. The antioxidant activity was analyzed by DPPH scavenging
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The thermodynamic driving force in entrepreneurship J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2024-01-26 David Leong
This study explores the thermodynamic underpinnings of venture creation, providing a fresh perspective on entrepreneurship, especially impulsive, non-deliberative actions in seizing opportunities. Thermodynamics clarifies various natural processes and offers insights into entrepreneurial behaviour. Entrepreneurs, driven by profit potential, often take risks under uncertainty. The paper proposes a
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Macrophage plasticity enhanced by camel milk peptide attributes in wound healing in diabetic rats J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2024-01-06 Jameel Al-Tamimi, Ibrahim M. Alhazza, Hossam Ebaid, Iftekhar Hassan, Sufia Husain, Saleh Alwasel, Ashraf Mashaly
Diabetes Mellitus during wound healing alters macrophage recruitment, leading to delayed healing. The present study focuses on impact of camel milk peptide (CMP) on macrophage plasticity during their recruitment during wound healing stages. The Swiss albino rats were distributed into three groups: a normal wounded group (control), a wounded diabetic group, and a wounded diabetic group treated with
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Assessment of Ailanthus altissima seed oil as a potential source for biodiesel production using nickel oxide nanoparticles catalyst J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2024-01-04 Hammad Ahmad Jan, Ahmed Sadeq Al-Fatesh, Ahmed I. Osman, Igor Surina, Fazli Rahim, Ali Sher
The identification of suitable non-edible plant feedstock is crucial not only to meet energy demands but also to be environmentally friendly. This study aimed to synthesize nickel oxide (NiO) nanoparticles and use these for synthesizing biodiesel from the non-edible feedstock Ailanthus altissima. The confirmation of NiO synthesis and its characteristics were studied using XRD and SEM. The biodiesel
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The impact of Bi3+ ions on magnetization, dielectric parameters, and conductivity of soft Mg-Cu ferrite nanoparticles J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-12-31 Hanaa Almaghamsi
This paper investigates the bismuth ions leverage on magnetic and dielectric features of magnesium–copper nanoferrites Mg0.5Cu0.5BixFe2-xO4 (MCBF). The Mg0.5Cu0.5Bi0.1Fe1.9O4 nanoferrite exhibits superior magnetic properties compared to the pure Mg-Cu sample. These properties include a higher magnetization of 31.31 emu/g, with an enhancing ratio of 1.50 %. Additionally, it demonstrates a higher initial
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Role of reactive oxygen species: In the cytotoxicity and apoptosis of colon cancer cell line due to green lead nanoparticles J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-12-03 May A. Alshahrani, Khadijah N. Yaseen, Rafa A. Almeer, Saud Alarifi
Nanoparticles are involved in regulating the biology of cancer cell treatment, but their mechanism is not fully understood. We synthesized and characterized new green lead nanoparticles (gPbNPs) by using an extract of Ziziphus spina christi leaves. Its cytotoxic and apoptotic effect on the human colon cancer Cacoa2 cell line was evaluated. The gPbNPs were characterized by using energy dispersive X-rays
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Protective effects of nobiletin against metabolic and reproductive disturbance in letrozole induced polycystic ovarian syndrome in rats J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-12-05 Muhammad Umar Ijaz, Muhammad Muzammil Sultan, Moazama Batool, Asma Ashraf, Mikhlid H. Almutairi, Ayesha Ishtiaq
The most prevalent metabolic and endocrine abnormality affecting women globally is polycystic ovarian syndrome (PCOS). This research was planned to elucidate whether nobiletin (NOB) has curative effects on the biochemical, metabolic, androgenic as well as histological components of PCOS in rats. 24 female albino rats were divided into 4 equal groups: Group-I was given with 2 ml/kg of 0.5% carboxymethyl
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Association between consumption of tryptophan with sleep quality in King Saud University students J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-12-05 Nora Alafif
This study aimed to evaluate the relationship between sleep quality and tryptophan consumption in King Saud University students by using a PSQ1 questionnaire. This study was conducted during the COVID-19 pandemic, and it included 122 Saudi students, who received the PSQ1 questionnaire via Twitter, Telegram, and WhatsApp. All data was encoded in Excel for statistical analysis. Generally, low consumption
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Aucubin mitigates nonylphenol-induced renal damage by attenuating apoptosis, oxidative stress and histopathological profile J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-12-05 Naila Ghafoor, Nazia Ehsan, Muhammad Faisal Hayat, Rabia Azmat, Mukhtar Ahmed, Ayesha Ishtiaq
Nonylphenol (NP) is potent noxious pollutant which is documented to induce nephrotoxicity via escalating the levels of oxidative stress in renal tissues. Aucubin (AUC) is a novel phytochemical having tremendous pharmacological abilities. This research aimed to estimate the efficacy of AUC against NP intoxicated renal impairment in male albino rats. 48 albino rats were randomly assigned into four different
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Identification, evaluation the source of natural bioactive compounds from Calotropis gigantea l. flowers and their anticancer potential J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-30 Sandhanasamy Devanesan, Mohamad S. AlSalhi
Background In the intensified search to derive biologically active compounds from natural products for various health care issues, attention is focused on non-edible plant sources. Among the wild plants, Calotropis [milk weeds] of the family Apocynaceae, are the repository of pharmaceutically active phytoconstituents. The flowers of C. gigantea are expected to be rich in bioactive compounds. Methods
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Assessment of a nanobiofungicide with antimicrobial potential against mycopathogenic Fusarium species J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-29 Abdul Ghani, Syed Ali Imran Bokhari, Syed Anees Ali, Muhammad Faheem, Suliman Yousef Alomar, Muhammad Mudassir Basheir, Naushad Ahmad, Sana Irshad
Objectives In the current study, a new potential nanobiofungicide was investigated as hybrid composite antifungals; zinc oxide nanoparticles (ZNPs) in combination with microbial hydrolytic enzymes (Chitinases). Methods The Chitinase enzyme was achieved from a local isolate, which was identified as Bacillus licheniformis AG-W3. The enzyme production was achieved after 72 h of incubation at pH 7.5 and
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Investigation of Bioactive constituents and evaluation of different in vitro antimicrobial, antioxidant, and cytotoxicity potentials of different Portulacaria afra extracts J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-27 Shumaila Ijaz, Javed Iqbal, Banzeer Ahsan Abbasi, Sobia Kanwal, Maryam Tavafoghi, Mohammad Z. Ahmed, Tariq Mahmood
The use of medicinal plants exists before the existence of humans. Healing with herbal treatments is of utmost significance because medicinal plants contain bioactive compounds. The objective of the current investigation was to evaluate the biological potential of methanolic (PAM) and chloroform (PAC) extracts of Portulacaria afra root, leaf, seed and flower. FT-IR (Fourier Transform Infrared Spectroscopy)
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Mechanical properties of Okuzgozu (Vitis vinifera L. cv.) grapevine canes J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-25 F. Goksel Pekitkan
Background The mechanical properties of Okuzgozu grapevine canes influence pruning and harvesting techniques, grape quality, and the feasibility of using mechanical harvesters. Methods This study determined the optimal cutting qualities for the native Okuzgozu grape variety (Vitis vinifera L.) over a range of phenological stages and cane diameters. The cutting tests of canes were performed at different
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Molecular perspective on starfish tissue extracts: targeting human carcinoma KB cells for anticancer therapy J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-27 Prithiviraj Nagarajan, Sivakumar Allur Subramanian, Chandramohan Govindasamy, Ahmed S. El Newehy, Leena Rajathy Port Louis, Mohan Sivanandham, Kumar Rangarajalu, Casimeer C. Sangeetha, Ahmad Y Ghidan, Alaa Yousef Ghidan
The marine environment is rich in natural bioactive compounds, including zebrafish and starfish species, which have garnered attention in drug research for their remarkable tissue regeneration abilities. Zebrafish, in particular, share a genetic resemblance of around 70% with humans. We chose to investigate Luidia maculata, a starfish species, due to its remarkable tissue regeneration abilities and
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A comprehensive overview on the preservation techniques and packaging of processed meat products: Emphasis on natural derivatives J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-26 Selvaraj Arokiyaraj, Yuvaraj Dinakarkumar, Hakdong Shin
Consumer's perspective on the quality is a variable that makes preservation and processing of various meat products a difficult task. To overcome the issue of spoilage and shelf life extension, with the expanded interest in maintaining a good quality of raw meat items, innovations took a lead in preservation techniques. Many innovations, such as applying high hydrostatic pressure, super chilling process
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Reduction in phytotoxicity of a textile wastewater against Vigna radiata using Citrobacter sp. M41 in a bioaugmented packed bed column bioreactor J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-24 Yasir Bilal, Tauseef Sarwar, Etisam Mazhar, Faisal Mahmood, Tanvir Shahzad, Dunia A Al-Farraj, Inshad Alzaidi, Mohamed S Elshikh, Tse-Wei Chen, Sabir Hussain
The current research was carried out to devise a biological strategy to remediate dyes and metal ions from textile wastewater. For this purpose, Citrobacter sp. M41 was isolated from a textile wastewater sample. This strain efficiently decolorized > 90% of the added reactive black-5 (RB5) dye using yeast extract as a C source at 8.5 pH and 30 °C in mineral salt medium containing a mixture of metals
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Anticancer effects of pH- sensitive carvacrol zinc oxide quantum dots on DMBA induced mammary carcinoma in female sprague dawley rats J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-24 Srinivasan Manoj Kumar, Briska Jifrina Premnath, Ramya Parimelazhagan, Chandramohan Govindasamy, Kamala-Kannan Seralathan, Nalini Namasivayam
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Cholinesterase inhibitory activity and regioselective synthesis of spiropyrrolidinoindole integrated ferrocene hybrid heterocycles via multicomponent cycloaddition reaction J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-24 Abdulrahman I. Almansour, Khloud Ibrahim Al-Shemaimari, Shatha Ibhrahim Alaqeel
A novel spiroheterocyclic hybrid comprising several privileged structures comprising pyrrolidine, quinoxaline, indole and ferrocene moieties were synthesized in good yields in sustainable fashion using [Bmim]Br augmented four component cycloaddition process. A relatively less explored ylide prepared from quinoxalinone and L-tryptophan with diverse ferrocenyl derivatives in ionic liquids afforded s
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Time dependent inhibition of Morinda citrifolia essential oils against multi drug resistant bacteria and A549 lung cancer cells J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-24 Govindan Rajivgandhi, Chenthis Kanisha Chelliah, Govindan Ramachandran, Gnanasekaran Chackaravarthi, Mohan Narayanan, Muthuchamy Maruthupandy, Franck Quero, Arulraj Arunachalam, Mangalaraja Ramalinga Viswanathan, Jamal M. Khaled, Wen-Jun Li
Recent years, multi-drug resistant bacteria (MDRs) and lung cancer cells are threatening to human worldwide due to failure of sufficient drugs. It was suggested that the new sources needed to discover new varieties of drugs, antibiotics and other format to eradicate these infections. As like, the medicinal plant of Morinda citrifolia (M. citrifolia) was used in this study to inhibit both the bacterial
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Molecular structure, stability and spectroscopic properties of verteporfin and its derivatives – A theoretical insight J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-24 Raju Suresh Kumar, Abdulrahman I. Almansour, Natarajan Arumugam, Khloud Ibrahim Al-Shemaimari, Sakkarapalayam M. Mahalingam, Sakkarapalayam Murugesan Senthil Kumar
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Analysis of a Discrete Time Fractional-Order Vallis System J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-20 Şeyma ŞİŞMAN, Mehmet MERDAN
Vallis system is a model describing nonlinear interactions of the atmosphere and temperature fluctuations with a strong influence in the equatorial part of the Pacific Ocean. As the model approaches the fractional order from the integer order, numerical simulations for different situations arise. To see the behavior of the simulations, several cases involving integer analysis with different non-integer
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Design, stereoselective synthesis and anticancer efficacy of a new class of functionalized pyrrolizidine heterocyclic hybrids J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-22 Raju Suresh Kumar, Dhaifallah M. Al-thamili, Khloud Ibrahim Al-Shemaimari, Faruq Mohammad, Mohamad Altaf, Rashid Ayub
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Drought-induced changes in plant-yield interlinked biochemistry of cauliflower (Brassica oleracea L. var. botrytis) by exogenously applied alpha-tocopherol J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-21 Nimra Zafar, Nudrat Aisha Akram, Kaneez Fatima, Sibgha Noreen, Muhammad Sohail Akram, Saliha Umer, Muhammad Ashraf, Abdulaziz Abdullah Alsahli, Sheikh Mansoor
To assess the potential of exogenously-applied vitamin E commonly known as alpha-tocopherol (α-TOC) in drought stress tolerance, an experiment was performed on cauliflower (Brassica oleracea L. var. botrytis) plants. Two cultivars (TCF-605 and White Figer) of cauliflower were subjected to control and drought stress conditions. After thirty days of drought stress treatment, cauliflower plants were treated
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Quantifying anticancer drug toxicity on white blood cell count in cancer patients: A mathematical and computational approach J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-20 Muhammad Adeel, Muhammad Khalid, Abdel Halim Harrath, Lassaad Mchiri, Lamjed Mansour
Objectives White blood cells (WBCs) are immune cells that fight infections and cancers. However, many cancers and their treatment with chemotherapy negatively affect the WBCs count. For oncologists and physicians, it is important to know how much the WBCs count is affected to optimize drug administration. The data of breast cancer patients were included in this study because the largest number of cancer
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Zn-Modified In2O3 Nanoparticles: Facile Synthesis, Characterization, and Selective Cytotoxicity against Human Cancer Cells J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-18 ZabnAllah M. Alaizeri, Hisham A. Alhadlaq, Mohd Javed Akhtar, Saad Aldawood
Oxide nanoparticles (NPs) have attracted considerable interest owing to their unique characteristics and possible applications, including gas detection, bioanalytical sensing, catalytic, and biomedical. The present work was designed to explore the effect of varying amounts (2.5%, 5%, and 7.5 mol%) of Zn-doping on the properties and selective anticancer efficacy of In2O3 NPs. The precipitation process
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Different drying techniques effect on the bioactive properties of rose petals J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-19 Ahmad Mohammad Salamatullah, Mohammed Asif Ahmed, Khizar Hayat, Fohad Mabood Husain, Shaista Arzoo, Abdulhakeem Alzahrani, Asdaf Alotaibi, Heba Khalil Alyahya, Syed Rizwan Ahmad
This study explored the effect of different drying methods (sun, shade, oven) on the total polyphenol content (TPC) using the Folin–Ciocalteu (FC) procedure, total flavonoid content (TFC) using the AlCl3 colorimetric method, volatile organic compounds using GC/MS and the antioxidant properties of the rose petals using the protocol of DPPH assy. The results demonstrated that the drying methods had a
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Comparing the efficacy of blind vs. ultrasound-guided injections in Lateral Epicondylitis: A prospective analysis J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-19 Muiez Bashir, Zahid Manzoor Khanday, Mohammad Farooq Mir, Wasim Akbar Bhat, Sheikh Viqar Javid, Saad Alkahtani, Carmen Vladulescu, Imtiaz Cynthia
Lateral epicondylitis is a relatively common non-traumatic elbow disorder. It is a painful musculoskeletal condition that usually follows forceful repetitive pronation and supination. The aim of this study was to evaluate the advantages of ultrasound-guided injection in patients of Lateral Epicondylitis in comparison to non-image-guided blind injections. This comparative observational study was conducted
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Prospects of the Sustainability of Traditional and Ethnic Foods and their Applications for Basic Health Care in Human Society J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-17 Tauseef Anwar, Hafsa Naeem, Huma Qureshi, Asma Hanif, Sadaf Anwaar, Ejaz Hussain Siddiqi, Zobia Noreen Resource, Javed Iqbal, Baber Ali Resource, Rashid Iqbal, Bilal Ahamad Paray
Background Traditional and ethnic foods, rooted in centuries-old practices, have long been revered for their potential health benefits. In contemporary society, the sustainability and application of these foods for basic health care are garnering increased attention, offering promising prospects for holistic well-being. Methods In our research, we aimed to document the medicinal plants utilized by
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Analysis of the shoreline changes using geoinformatics in Ghoramara Island of Hugli Estuary, West Bengal in India J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-15 Biraj Kanti Mondal, Sanjib Mahata, Rima Das, Rajib Patra, Tanmoy Basu, Kamal Abdelrahman, Mohammed S. Fnais, Sarbeswar Praharaj
Conceptual Framework Coastal decrepitude is the loss of topographical resources along the coast as a result of silt, temperature fluctuations, tidal shifts, and wave breaking. Hydraulic activity, scraping, abrasion, and erosion are the major causes of erosion; other factors that affect it include the condition of the shore, rocks, joints, fissures, marine chemical reactions, and wave force. Objectives
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Antidiabetic activity evaluation of polyherbal formulation in type 2 diabetes mellitus patients J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-14 Muhammad Muzaffar Ali Khan Khattak, Nor Azwani Mohd-Shukri, Tahir Mahmood, Mukhtar Ahmed, Syed Najmul Hejaz Azmi, Mahboob Alam, Murni Nazira Sarian, Qamar Uddin Ahmed
Objective The main aim of this research was to evaluate the effect of mixed herbs on blood HbA1c, and the liver function tests in type 2 diabetes mellitus (T2DM) patients. Methods This was a quasi-experimental design where no comparison was made with either placebo or control. We examined the effect of herbs namely, coriander leaves (Coriandrum sativum), bunching onion (Allium fistulosum), curry leaves
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Exogenous citric acid improves growth and yield by concerted modulation of antioxidant defense system in brinjal (Solanum melongena L.) under salt-stress J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-14 Naila Ali, Rafia Rafiq, , Leonard Wijaya, Ajaz Ahmad, Prashant Kaushik
Brinjal is sensitive to salinity, a common factor responsible for reducing its biomass and yield components. Recent research has demonstrated that citric acid/citrates can provide abiotic stress resistance in plants. In this study, Brinjal variety Pusakranti was treated with four concentrations of CA at 0, 100, 200, and 300 ppm applied foliarly under two levels of salt stress (0 mM and 60 mM NaCl)
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Antioxidant, antibacterial, and cytotoxic activities of cimemoxin derivatives and their molecular docking studies J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-14 Velmurugan Loganathan, Anis Ahamed, Idhayadhulla Akbar, Saud Alarifi, Gurusamy Raman
Purpose The cimemoxin derivatives and their biological importance in antioxidant, antibacterial, and cytotoxic activities were the main focus of this study. By using a one-step reaction and green chemistry method, this study was able to synthesise derivatives of cimemoxin-related Mannich base compounds. Methods Green chemistry can be used to prepare new, one-pot syntheses of cimemoxin derivatives (1a-i)
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Ecological risk assessment of heavy metals contamination in agricultural soil from Al Majma'ah, central Saudi Arabia J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-08 Khaled Al-Kahtany
Soil acts as a tank for heavy metals through surface complexation, ion exchange and surface precipitation. The purpose of this study was to assess the contamination and ecological risk of heavy metals (HMs) in agricultural soil in the Al Majma'ah area of central Saudi Arabia. Soil samples from 34 farms were collected, and HMs were evaluated using inductively coupled plasma-atomic emission spectrometry
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A single server Non-Markovian with non-compulsory re-service and balking under Modified Bernoulli Vacation J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-13 Bharathi J., Nandhini S.
In this paper, a single-server queue with Modified Bernoulli Vacation(MBV) has been considered. The server provides two kinds of services, Compulsory Service (CR) and Non-Compulsory Re-service (NCR). Any new customer who arrives and finds the server engaged, on breakdown, or on vacation will be placed on an orbit; or else if he finds the server free, he enters the service immediately. The server takes
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Micromeria Biflora Mediated Gold and Silver Nanoparticles for Colourimetric Detection of Antibiotics and Dyes Degradation J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-10 Naeem Khan, Fakhra Kalsoom, Nargis Jamila, Shaukat Shujah, Azhar Ul-Haq Ali Shah, Umar Nishan, Muhammad Ishtiaq Jan, In Min Hwang, Mohamed S. Elshikh, Riaz Ullah
The study reports on synthesis of aqueous extract mediated gold and silver nanoparticles of M. biflora (MBAuNPs and MBAgNPs) via hydrated chloroauric acid and silver nitrate salts. The nanoparticles (NPs) were produced in 1:15 (MBAuNPs) and 1:6 (MBAgNPs) ratios under sunlight displaying localized surface plasmon resonance (LSPR) peaks at 541 and 431 nm, respectively. The sizes characterized by transmission
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Development of prediction model for body weight and energy balance indicators from milk traits in lactating dairy cows based on deep neural networks J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-11 Eunjeong Jeon, Sangbuem Cho, Seongsoo Hwang, Kwanghyun Cho, Cedric Gondro, Nag-Jin Choi
To develop a body weight (BW) prediction model using milk production traits and present a useful indicator for energy balance (EB) evaluation in dairy cows. Data were collected from 30 Holstein cows using an automatic milking system. BW prediction models were developed using multiple linear regression (MLR), local regression (LOESS), and deep neural networks (DNN). Milk production traits readily available
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Corrigendum to “Effects of diminazene aceturate on flip-flop plasma pharmacokinetics of piroxicam in dogs” [J. King Saud Univ. – Sci. 35(8) (2023) 102914] J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-09 Saganuwan Alhaji Saganuwan, Otiger Fredrick Egworrow, Agbo Joseph Ode
Abstract not available
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Antimicrobial evaluation of spirooxindolopyrrolidine engrafted indoles against multidrug resistant ESKAPE clinical pathogens J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-10 Natarajan Arumugam, Khloud Ibrahim Al-Shemaimari, Mohammad Altaf, Karuppiah Ponmurugan, Dhanaraj Premnath, Sinouvassane Djearamane, Ling Shing Wong, Saminathan Kayarohanam
The synthesis of a new class of effective antibiotics and antimicrobial agents with less toxicity is highly desirable due to bacterial resistance to antibiotics has increased dramatically. In this context, molecules that embedding a spiro moiety are attractive from a medicinal chemistry point of view as these spiro heterocycles show a vital part in the development of delivery systems for antimicrobial
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Determination of the health-protective effect of different Sempervivum and Jovibarba species J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-10 Zsolt Giczi, Beatrix Sik, Viktória Kapcsándi, Erika Lakatos, Angéla Mrázik, Rita Székelyhidi
This study aimed to examine the micro- and macroelements, as well as the total antioxidant, and polyphenol content of 22 different types of dried houseleek, and fresh plant decoctions. The measurement of antioxidant and polyphenol content was carried out with two drying methods- a drying cabinet and lyophilization. The plants, without exception, were provided by Berger Trio Kft. from Jánossomorja (Hungary)
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Jaffrey-Hamel flow features of Oldroyd-B model through intersecting plates J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-10 Sohail Rehman, Souhail Bouzgarrou, , Mehdi Akermi
We evaluate the steady Jaffrey-Hamel flow of a viscoelastic fluid using Oldroyd-B model in a deformable channel formed by two intersecting plates. To be more precise, we offer a mathematical structure for computing the leading-order impacts of the fluid viscoelasticity on the flow in the setting of relaxation and temporal retardation interactions between the fixed walls of the channel. The typical dimensionless
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Phytochemical screening and in vitro evaluation of antioxidant and antimicrobial efficacies of Pteropyum scoparium (Jaub. & Spach) Sidaf crude extracts J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-09 Vijaya Saradhi Settaluri, Tuqa Mohammed Al Anbari, Shahad Khalifa Al Shukaili, Raqiya Mohammed Al Rawahi, Syed Najmul Hejaz Azmi, Pankaj Sah, Salla Hemadri Reddy, Qamar Uddin Ahmed, Shaik Althaf Hussain, Jayasimha Rayalu Daddam, Stuti Sah, Sultan Mahmood
Objective Pteropyrum scoparium Jaub. & Spach locally known as “Sidaf” is a meal known to the ancient Omani people with many health benefits. It is traditionally used in Oman to treat high cholesterol, hypertension, indigestion problems, wound healing, and diabetes. However, these claims are yet to be scientifically proven. Hence, this study aimed to perform phytochemical, antioxidant, and antimicrobial
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Morphological and biochemical variations caused by salinity stress in some varieties of Pennisetum glaucum L. J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-07 Muhammad Rashid, Sibgha Noreen, Kausar Hussain Shah, Abdel-Rhman Z. Gaafar, Rooma Waqar
The salinity of the soil is a severe challenge to the sustainability of agricultural production. It causes significant loss in the productivity of crop plants. To overcome this problem, one of the possible solutions could be the identification and cultivation of salinity tolerant crop plants in salt affected land. Therefore, this study was designed to screen some varieties of Pearl Millet (Pennisetum
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Evaluation of different High doses Aqueous Plant Extracts for the Sustainable Control of Aedes aegypti Mosquitoes under Laboratory Conditions J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-04 Afaq Ahamd, Gul Zamin Khan, Misbah Ullah, Nazeer Ahmed, Kamran Sohail, Irfan Ullah, Najat A. Bukhari, Kahkashan Perveen, Ijaz Ali, Ke Li
Aedes aegypti mosquitoes represent a significant public health hazard as they serve as vectors for a variety of arboviral infections, including Dengue, Zika, and Chikungunya. This necessitates the development of efficacious vector control strategies. The current study conducted at the Medical Entomology laboratory of the Nuclear Institute for Food and Agriculture (NIFA) Peshawar, Pakistan, evaluated
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Bioactivity of Natural Compounds Extracted from Oedogonium cilitum isolated from Qalachwalan pond J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-04 Trifa kamal jalal, Trifa Attar Omar
Natural extracts of microalgae are widely recognized for their biologically active compound. They represent an untapped supply of pharmaceutical substances. In this study, the freshwater macroalgae (Oedogonium cilitum) was collected from Qalachwalan Pond in Sulaimani City. The sample was identified, authenticated, and investigated for their chemical composition and pharmacological properties. the GC/MS
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Compost and chemical fertilizer triggered pedospheric compartment’s varied response and phyto-morphological alterations in Helianthus annuus J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-03 Tahreem Taswar, Shazia Iram, Sibgha Noreen, Seema Mahmood, Abdel-Rhman Z. Gaafar, Daniel Ingo Hefft
Chemical fertilization of soils has been adopted as a productivity-boosting mode for many years but it is marked by excessive synthetic chemical utilization and significant persistence in the ecological matrices. Current research has for the first adopted a cost-effective, eco-friendly, and sustainable mode of soil fertilization and consequent growth augmentation of Helianthus annuus by utilization
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Magnetic anomaly interpretation for a 2D fault-like geologic structures utilizing the global particle swarm method J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-02 Khalid S. Essa, Eid R. Abo-Ezz, Yves Géraud, Marc Diraison, Alan B. Reid
We establish a method to interpret the magnetic anomaly due to 2D fault structures, with an evaluation of first moving average residual anomalies utilizing filters of increasing window lengths. After that, the buried fault parameters are estimated using the global particle swarm method. The goodness of fit among the observed and the calculated models is expressed as the root mean squared (RMS) error
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Therapeutic potential of kaempferide against paraquat instigated cardiac toxicity in rats J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-10-30 Muhammad Umar Ijaz, Syeda Sania Zahara, Moazama Batool, Mikhlid H. Almutairi, Ayesha Ishtiaq, Asma Ashraf
Paraquat (PQ) is an effective herbicide however, due to its adverse effects on different organs including heart, it is considered as highly toxic to human beings. Kaempferide (KMF) is a plant-based flavonoid with conspicuous pharmacological properties. This experiment was executed to evaluate the palliative actions of KMF on PQ prompted cardiac toxicity in rats. Twenty-four rats were apportioned into
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Enhancing hyperspectral remote sensing image classification using robust learning technique J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-10-30 Alaa Ali Hameed
Advanced sensor tech integrates into diverse applications, including remote sensing, robotics, and IoT. Combining artificial intelligence (AI) with sensors enhances their capabilities, creating smart sensors, revolutionizing remote sensing and Internet of Things (IoT). This synergy forms a potent technology in the field. This study carries out a comprehensive analysis of the progress made in Hyperspectral
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Evaluation and chemical profiling of different Centaurea iberica extracts and investigation of different in vitro biological activities J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-04 Haleema Bibi, Javed Iqbal, Banzeer Ahsan Abbasi, Sobia Kanwal, Maryam Tavafoghi, Mohammad Z. Ahmed, Tariq Mahmood
In almost all cultures medicinal plants are used as a rich source of phytochemicals and nutraceuticals components and have played promising role in maintaining and improving human health. The current study was aimed to unveil biological evaluation of Centaurea iberica. Plant extracts were prepared in five different solvents viz. methanol, ethanol, n-hexane, ethyl acetate and chloroform. The antioxidant
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Molecular characterization and evolutionary history analysis of a novel Kudzu mosaic virus (KMV) infecting the Kudzu (Pueraria montana) J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-02 Muhammad Waheed Riaz, Muhammad Arif, Yasir Mehmood, Mehmet Ertugrul Gulddur, Aicun Zhou, Shikhah K Alnemar, Mona S Alwahibi
Objectives Plant viruses are a significant contributor to the economic losses experienced in numerous plant species. Begomoviruses exhibit a wide range of host species, encompassing both cultivated and non-cultivated plants. The kudzu plant, scientifically known as Pueraria montana, is indigenous to the Southeast Asian region. Moreover, it exhibits varied attributes with regards to its utilization
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Solanesol alleviates metal oxide nanoparticles generated toxicity in human placental BeWo cells J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-02 Rashid Lateef, Israr Ahmad, Abbas Ali Mahdi, Pavan Rajanahalli, Mohd Javed Akhtar, Maqusood Ahamed
Recent research has provided evidence that metal oxide nanoparticles (NPs) have the potential to traverse the placental barrier, potentially endangering the health of both pregnant individuals and the developing fetus. The function of oxidative stress is of utmost importance in the pathophysiology of poor pregnancy outcomes. The therapeutic potential of solanesol in mitigating pregnancy complications
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Aloe vera mucilage as an eco-friendly corrosion inhibitor for bronze in chloride media: Combining experimental and theoretical researches J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-01 Bouchra Benzidia, Mohammed Barbouchi, Malak Rehioui, Hind Hammouch, Hamid Erramli, Najat Hajjaji
Aloe vera (L.) Burm.F. (= Aloe barbadensis Mill.), a widely recognized medicinal plant, holds a prominent position due to its potent cosmetic and medicinal attributes. The objective of this work is to develop a new eco-friendly corrosion inhibitor for bronze B66 that is non-toxic, simple to apply, cost-effective, stable, and reversible. To achieve this goal, we initially devised an improved and cost-efficient
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Cobalt-based nanoparticles strongly diminish CalceinAM fluorescence independently of their cytotoxic potential in human lung cell line J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-11-01 Mohd Javed Akhtar, Maqusood Ahamed, Hisham Alhadlaq
Objective Cobalt nanoparticles (NPs) when released into the air during industrial processes, can enter the lungs through inhalation, leading to potential toxicity and respiratory issues. The mechanism of cobalt toxicity is not well understood and needs further investigation. Methods We, therefore, studied the effects of two kinds of cobalt-based nanoparticles (NPs) on lung cells. These NPs were Co
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Immunoprophylactic potential of recombinant outer membrane protein of Salmonella enterica serovar Typhi against enteric fever in BALB/c mice J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-10-31 Kunza Latif, Shagufta Naz, Imran altaf, Rasheeda Bashir, Faiza Saleem, Neelma Munir, Farheen Aslam
Objectives This study was design to explore the immunogenic behavior of LamB and SpaO outer membrane protein of Salmonella serovar Typhi against enteric fever in BALB/c mice. Methods SpaO or LamB genes of locally isolated strain of S.Typhi was amplified, cloned and expressed. Recombinant protein SpaO and LamB were purified and lyophilized to prepare aluminum hydroxide Gel precipitated vaccine. Clinical
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Design and Realization of Data Mining Simulation and Methodological Models J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-10-29 Zhang Zong Biao
Data mining in education is steadily gaining momentum to explore the learning analytics because of its easy to use with any programming knowledge. This emerging method primarily focus on developing methods for handling and exploring voluminous information represented in distinct types of data. Deployment of data mining in education helps to better understand the synergy between the learning and educational
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Cytotoxicity of silver nanoparticles green-synthesized using Olea europaea fruit extract on MCF7 and T47D cancer cell lines J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-10-26 Njud S. Alharbi, Afnan I. Felimban
To develop a more environmentally friendly, low-cost, energy-efficient, and non-toxic strategy for producing silver nanoparticles (AgNPs) for cancer therapy, in this study, we established a green synthesis method using Olea europaea fruit extract (OFE) as a reducing and stabilizing agent for the AgNPs. The AgNPs were then characterized using relevant spectroscopy and other analyses, and their cytotoxicity
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Assessment of sunscreen effects in photosensitivity under UV exposure during COVID-19 pandemic J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-10-26 Sara Mumtaz, Atif Ali, Hajra Muhammad Sharif, Reem M. Aljowaie, Asma N. Alsaleh, Hira Khan, Muhammad Naeem, Arshad Mehmood Abbasi
The aim of this work was to assess the effects of typical and optimal use of sunscreens in photosensitivity under UV exposure during the COVID-19 pandemic. First, a cross-sectional study was conducted among 384 participants to find out about photosensitivity in COVID-19 pandemic using a validated questionnaire involving demographic characteristics and Fitzpatrick skin type to measure skin phototypes
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Discovery of secondary metabolites from Avicennia marina to inhibit the anti-oxidant and anti-biofilm activities of biofilm forming bacteria J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-10-30 Govindan Rajivgandhi, Chenthis Kanisha Chelliah, Manavalan Murugan, Govindan Ramachandran, Gnanasekaran Chackaravarthi, Muthuchamy Maruthupandy, Franck Quero, Arulraj Arunachalam, Mangalaraja Ramalinga Viswanathan, Jamal M. Khaled, Fetim S. AlHarbi, Wen-Jun Li
The present study is concentrated on screening of phytochemical and bioactive compounds from marine mangrove plant of Avicennia marina (A. marina). The plant extract was purified by soxhlet extraction process, and the available phytochemicals, bioactive compounds and other organic compounds were confirmed by LC-MS analysis. Subsequently, the antioxidant and DPPH scavenging activities of the A. marina
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Influence of Heat Treated files on conserving the Remaining Dentin Thickness during Endodontic Retreatment – An Invitro CBCT study J. King Saud Univ. Sci. (IF 3.8) Pub Date : 2023-10-27 Mulumoodi Rama Sowmya, Pradeep Solete, Ganesh Jeevanandan, S. Surendar, Shashit Shetty Bavabeedu, Amal shaiban, Zeeshan Heera Ahmad, Thodur Madapusi Balaji, Shilpa Bhandi
Objectives Non-surgical endodontic retreatment is to be a conservative option over endodontic surgery in case of recurrent infections. Root canal retreatment procedures needs to be initiated faster and proficiently with proper root canal retreatment files. The main aim of this study is to evaluate the remaining root dentin thickness post Gutta Percha (GP) retrieval from the root canal after using two