Genetic approaches to cancer research have dramatically advanced our understanding of the pathophysiology of this disease, leading to similar genetics-based approaches for precision therapy, which have been less successful. Reconfiguring and adapting the types of technologies that underlie genetic research to dissect tumor cell signaling in clinical samples may offer an alternative road forward.

中文翻译：

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为什么即使癌症主要是信号传导疾病，遗传学家仍偷走了癌症研究

癌症研究的遗传方法极大地增进了我们对这种疾病的病理生理学的理解，从而导致了类似的基于遗传的精确治疗方法，但效果较差。重新配置和适应基因研究基础的技术类型，以剖析临床样品中的肿瘤细胞信号可能会提供一条替代性的发展之路。