The cumulative incidence of candidaemia in an Irish intensive care unit (ICU) setting between January 2004 and August 2018 was 17/1000 ICU admissions. Candida albicans was responsible for 55% (N=41) of cases. C. glabrata (N=21, 28%) was the next most prevalent species, and has been identified most frequently since 2012. C. glabrata was associated with a higher mortality rate (57%) than C. albicans (29%). All isolates were susceptible to caspofungin (0.05 μg/mL). Notably, 37% of C. glabrata isolates were resistant to fluconazole, with 13% resistant to amphotericin B, highlighting the need for prudent antifungal stewardship to impede development of multi-drug-resistant C. glabrata in the ICU setting.

在2004年1月至2018年8月期间，爱尔兰重症监护病房（ICU）的念珠菌血症累积发病率为17/1000 ICU入院人数。白色念珠菌引起了55％（N = 41）的病例。光滑的C. glabrata（N = 21，28％）是第二流行的物种，自2012年以来最常被发现。光滑的C. glabrata的死亡率（57％）比白色念珠菌（29％）高。所有分离株均对卡泊芬净（0.05μg/ mL）敏感。值得注意的是，有37％的光滑念珠菌分离株对氟康唑有抗药性，对两性霉素B有13％的抗药性，强调了在ICU环境中需要谨慎的抗真菌药物管理以阻止对多药耐药的光滑毛衣藻的发展。