Multiplexed analysis has the advantage of allowing for simultaneous detection of multiple analytes in a single reaction vessel which reduces time, labor, and cost as compared to single-reaction-based detection methods. Microsphere-based suspension array technologies, such as the Luminex® xMAP® system, offer high-throughput detection of both protein and nucleic acid targets in multiple assay chemistries. After Luminex's founding in 1995, it quickly became the leader in bead-based multiplexing solutions. Today, xMAP Technology is the most widely adopted bead-based multiplexing platform with over 35,000 peer-reviewed publications, an installed base of approximately 15,500 instruments, and over 70 Luminex Partners offering more than 1300 research use kits as well as custom assay solutions. Because of the open architecture of the xMAP platform it has been implemented in a variety of applications that range from transplant medicine, biomarker discovery and validation, pathogen detection, drug discovery, vaccine development, personalized medicine, neurodegeneration, and cancer research.

中文翻译：

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基于微珠的多路复用的起源和演变

多重分析的优点是允许在单个反应容器中同时检测多种分析物，与基于单一反应的检测方法相比，这减少了时间、劳动力和成本。基于微球的悬浮阵列技术，例如 Luminex® xMAP® 系统，可在多种化学分析中提供蛋白质和核酸靶标的高通量检测。Luminex 于 1995 年成立后，迅速成为基于微珠的多路复用解决方案的领导者。今天，xMAP 技术是最广泛采用的基于微珠的多路复用平台，拥有超过 35,000 篇同行评审出版物、大约 15,500 台仪器的安装基础以及 70 多个 Luminex 合作伙伴，提供超过 1300 种研究使用套件以及定制化验解决方案。