Process systems engineering (PSE) tools can be utilized to enable the optimal operation and control of intensified processes. In this work, the challenges in the control of intensified processes are summarized, including the difficulties in modelling and performing online optimization of these highly complex dynamic systems. Nevertheless, PSE progress in the areas of nonlinear programming, reduced-order modeling, development of software tools, parallel computing and artificial intelligence are enabling the implementation and optimization of large-scale intensified systems. Future opportunities for research are identified, including the simultaneous optimization of scheduling of operation and control, a promising strategy that has proven its value in regular operations, and can expand the operating windows of intensified processes.

可以利用过程系统工程（PSE）工具来实现优化的操作和对强化过程的控制。在这项工作中，总结了强化过程控制中的挑战，包括在建模和执行这些高度复杂的动态系统的在线优化方面的困难。尽管如此，PSE在非线性程序设计，降阶建模，软件工具开发，并行计算和人工智能等领域的进步使大规模集约化系统的实现和优化成为可能。确定了未来的研究机会，包括同时优化运行和控制计划，这是一种有前途的策略，已在常规操作中证明了其价值，并且可以扩大集约化过程的操作窗口。