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A novel carbocatalytic hydride transfer strategy for efficient reduction of structurally different aldehydes and ketones in water
Tetrahedron Letters ( IF 1.8 ) Pub Date : 2019-01-11 , DOI: 10.1016/j.tetlet.2019.01.019
Vijai K. Rai , Suhasini Mahata , Smita R. Bhardiya , Prashant Shukla , Ankita Rai , Manorama Singh

Reduced graphene oxide (rGO)–NaBH4 is reported as mild and efficient catalyst-system for chemo-/regioselective reduction of structurally different aliphatic, aromatic as well as α,β-unsaturated aldehydes and ketones in water. The rGO was prepared by reducing graphene oxide using Tulsi leaf extract as bio-reductant. Operational simplicity, ambient reaction condition, high yield of pure products (80–97%), no by-product formation, no use of column chromatography for purification are the salient features of the envisaged protocol. Furthermore, the recovered TRGO was recycled and reused for subsequent reductions up to five times without any loss in activity.



中文翻译:

一种新颖的碳催化氢化物转移策略,用于有效还原水中结构不同的醛和酮

还原氧化石墨烯(rGO)–NaBH 4是温和有效的催化剂体系,用于化学/区域选择性还原水中结构上不同的脂肪族,芳香族以及α,β-不饱和醛和酮。通过使用塔尔西叶提取物作为生物还原剂还原氧化石墨烯来制备rGO。操作简便,环境反应条件良好,纯产物产率高(80-97%),不形成副产物,不使用柱色谱法进行纯化是所设想方案的主要特征。此外,回收的TRGO可以循环再利用,最多可减少五次,而不会造成任何活动损失。

更新日期:2019-01-11
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