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Palladium-catalyzed reductive Heck reaction of α,β-unsaturated alkenes and cycloalkyl iodides
Tetrahedron Letters ( IF 1.8 ) Pub Date : 2019-01-07 , DOI: 10.1016/j.tetlet.2019.01.010
Zhenwei Liu , Shanshan Wei , Apeng Liang , Jingya Li , Dapeng Zou , Yusheng Wu , Yangjie Wu

The palladium catalyzed reductive Heck reactions of unactivated cycloalkyl iodides with α,β-unsaturated alkenes have been developed. A number of hydrocycloalkylated alkenes were obtained in reasonable yields under the optimized conditions. The obvious advantage of this approach is that the hydride source was provided by Et3N and no other reductant or base was required in the reaction.



中文翻译:

钯催化的α,β-不饱和烯烃与环烷基碘的还原Heck反应

已经开发出未活化的环烷基碘与α,β-不饱和烯烃的钯催化的还原性Heck反应。在优化的条件下,以合理的收率获得了许多氢环烷基化的烯烃。这种方法的明显优点是,氢化物源是由Et 3 N提供的,反应中不需要其他还原剂或碱。

更新日期:2019-01-07
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