Unprecedented α‐oxygenated β,γ‐unsaturated ketones bearing a quaternary carbon at the α‐position were synthesized in two steps from readily available α,β‐unsaturated ketones. The compounds were prepared on a gram scale under mild conditions via a key rearrangement step catalysed by 1 mol% of p‐toluenesulfonic acid as a low‐priced and sustainable catalyst. The olfactory properties of this novel family of odorants as well as of some derivatives have been assessed, revealing a quite broad odour spectrum and a pronounced susceptibility of the olfactory properties towards structural changes.

中文翻译：

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烯丙基α-季醚酮的合成及嗅觉评价

由两个容易获得的α，β-不饱和酮分两步合成了前所未有的在α-位带有季碳的α-氧化的β，γ-不饱和酮。这些化合物是通过在1摩尔％的对甲苯磺酸作为低价且可持续的催化剂催化的关键重排步骤，在温和条件下以克级制备的。已经评估了该新颖的增香剂家族以及一些衍生物的嗅觉特性，揭示了相当宽的气味谱以及嗅觉特性对结构变化的显着敏感性。