We thank Dr Infantino and colleagues for their comments1 on our paper on assay variability in antinuclear antibody (ANA) testing by indirect immunofluorescence (IIF)2 and subsequent communications that have been published in the journal.3–7 We agree with their observations on assay variability as well as the potential role of computer-aided diagnosis in improving IIF determinations. The issue of titre is also important, although changing the …

中文翻译：

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回应：Infantino 等人的“现实生活中的 ANA 测试”

我们感谢 Infantino 博士及其同事对我们关于通过间接免疫荧光 (IIF) 进行抗核抗体 (ANA) 测试的测定变异性的论文的评论 2 以及随后发表在期刊上的通讯。 3-7 我们同意他们对测定的观察变异性以及计算机辅助诊断在改善 IIF 测定中的潜在作用。滴度问题也很重要，尽管改变了……