Compartmentalized translation allows rapid synthesis of proteins in targeted cellular locations. Microarray and RNA sequencing combined with physical subcellular separation methods have enabled extensive charting of subcellular transcriptomes. However, the extent of translating these local messages into protein remains relatively understudied at the genome-wide level. Here we review omics methods currently available for these studies, placing special attention on methods allowing cell-specific and subcellularly restricted analysis.

中文翻译：

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Omics进行亚细胞翻译研究的方法

分区翻译允许在目标细胞位置快速合成蛋白质。芯片和RNA测序与物理亚细胞分离方法相结合，已使广泛绘制亚细胞转录组的图表成为可能。但是，将这些局部信息翻译成蛋白质的程度在全基因组水平上仍处于相对研究不足的状态。在这里，我们回顾了目前可用于这些研究的组学方法，特别关注允许进行细胞特异性和亚细胞受限分析的方法。