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UPDATE ON THE POSSIBLE NUTRITIONAL IMPORTANCE OF SILICON
Journal of Trace Elements in Medicine and Biology ( IF 3.5 ) Pub Date : 2014-07-05 , DOI: 10.1016/j.jtemb.2014.06.025
Forrest H. Nielsen

Convincing evidence that silicon is a bioactive beneficial trace element continues to accumulate. The evidence, which has come from human, animal, and in vitro studies performed by several laboratories, indicate that silicon in nutritional and supra nutritional amounts promotes bone and connective tissue health, may have a modulating effect on the immune or inflammatory response, and has been associated with mental health. A plausible mechanism of action for the beneficial effects of silicon is the binding of hydroxyl groups of polyols such that it influences the formation and/or utilization of glycosaminoglycans, mucopolysaccharides, and collagen in connective tissue and bone. In addition, silicon may affect the absorption, retention or action of other mineral elements (e.g., aluminum, copper, magnesium). Based on findings from both animal and human experiments, an intake of silicon of near 25 mg per day would be a reasonable suggestion for an adequate intake that would assure its nutritional benefits. Increased intakes of silicon through consuming unrefined grains, certain vegetables, and beverages and cereals made from grains should be recognized as a reasonable dietary recommendation.



中文翻译:

硅可能的营养重要性更新

硅是一种具有生物活性的有益微量元素的令人信服的证据不断积累。来自多个实验室进行的人体、动物和体外研究的证据表明,营养和超营养量的硅可促进骨骼和结缔组织健康,可能对免疫或炎症反应具有调节作用,并具有与心理健康有关。硅的有益作用的一个可能的作用机制是结合多元醇的羟基,从而影响结缔组织和骨骼中糖胺聚糖、粘多糖和胶原蛋白的形成和/或利用。此外,硅可能会影响其他矿物元素(例如铝、铜、镁)的吸收、保留或作用。 每天毫克将是一个合理的建议,以确保其营养益处的充足摄入量。通过食用未精制的谷物、某些蔬菜以及由谷物制成的饮料和谷物来增加硅的摄入量应该被认为是合理的饮食建议。

更新日期:2014-07-05
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