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Minimum information reporting in bio-nano experimental literature.
Nature Nanotechnology ( IF 38.3 ) Pub Date : 2018-09-06 , DOI: 10.1038/s41565-018-0246-4
Matthew Faria 1, 2, 3 , Mattias Björnmalm 1, 2, 4, 5 , Kristofer J Thurecht 1, 6, 7 , Stephen J Kent 1, 8 , Robert G Parton 1, 9, 10 , Maria Kavallaris 1, 11, 12 , Angus P R Johnston 1, 13 , J Justin Gooding 1, 12 , Simon R Corrie 1, 6, 14 , Ben J Boyd 1, 13 , Pall Thordarson 1, 12 , Andrew K Whittaker 1, 6 , Molly M Stevens 1, 4, 5 , Clive A Prestidge 1, 15 , Christopher J H Porter 1, 13 , Wolfgang J Parak 16, 17 , Thomas P Davis 1, 13, 18 , Edmund J Crampin 3, 19 , Frank Caruso 2, 19
Affiliation  

Studying the interactions between nanoengineered materials and biological systems plays a vital role in the development of biological applications of nanotechnology and the improvement of our fundamental understanding of the bio–nano interface. A significant barrier to progress in this multidisciplinary area is the variability of published literature with regards to characterizations performed and experimental details reported. Here, we suggest a ‘minimum information standard’ for experimental literature investigating bio–nano interactions. This standard consists of specific components to be reported, divided into three categories: material characterization, biological characterization and details of experimental protocols. Our intention is for these proposed standards to improve reproducibility, increase quantitative comparisons of bio–nano materials, and facilitate meta analyses and in silico modelling.



中文翻译:

生物纳米实验文献中的最少信息报告。

研究纳米工程材料与生物系统之间的相互作用对于纳米技术的生物应用的发展和提高我们对生物纳米界面的基本理解起着至关重要的作用。这一多学科领域取得进展的一个重大障碍是已发表的文献在表征和报告的实验细节方面存在差异。在这里,我们为研究生物纳米相互作用的实验文献提出了“最低信息标准”。该标准由需要报告的具体组成部分组成,分为三类:材料表征、生物表征和实验方案细节。我们的目的是让这些拟议的标准提高可重复性,增加生物纳米材料的定量比较,并促进荟萃分析和计算机建模。

更新日期:2018-12-10
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