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Candidate genes linking maternal nutrient exposure to offspring health via DNA methylation: a review of existing evidence in humans with specific focus on one-carbon metabolism
International Journal of Epidemiology ( IF 7.7 ) Pub Date : 2018-08-17 , DOI: 10.1093/ije/dyy153
Philip James 1 , Sara Sajjadi 2 , Ashutosh Singh Tomar 2 , Ayden Saffari 1 , Caroline H D Fall 3 , Andrew M Prentice 1 , Smeeta Shrestha 2, 4 , Prachand Issarapu 2 , Dilip Kumar Yadav 2 , Lovejeet Kaur 2 , Karen Lillycrop 5 , Matt Silver 1 , Giriraj R Chandak 2 ,
Affiliation  

Mounting evidence suggests that nutritional exposures during pregnancy influence the fetal epigenome, and that these epigenetic changes can persist postnatally, with implications for disease risk across the life course.

中文翻译:

通过 DNA 甲基化将母体营养暴露与后代健康联系起来的候选基因:对人类现有证据的回顾,特别关注一碳代谢

越来越多的证据表明,怀孕期间的营养暴露会影响胎儿的表观基因组,并且这些表观遗传变化可以在出生后持续存在,从而影响整个生命周期的疾病风险。
更新日期:2018-08-17
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