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The antioxidant peptides from walnut protein hydrolysates and their protective activity against alcoholic injury Food Funct. (IF 6.1) Pub Date : 2024-03-27 Peihang Chen, Pantian Huang, Yingyan Liang, Jianyin Miao, Qiao-E Wang
In this study, walnut protein was hydrolyzed, separated by ultrafiltration, purified by RP-HPLC, identified by LC-MS/MS, and screened by molecular docking to finally obtain three novel antioxidant peptides HGEPGQQQR (1189.584 Da), VAPFPEVFGK (1089.586 Da) and HNVADPQR (949.473 Da). These three peptides exhibited excellent cellular antioxidant activity (CAA) with EC50 values of 0.0120 mg/mL, 0.0068
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Nutritional profiling, fiber content and in vitro bioactivities of wheat-based biscuits formulated with novel ingredients Food Funct. (IF 6.1) Pub Date : 2024-03-27 Marta Mesias, Francisco J. Morales, Cristina Caleja, Tânia C. S. P. Pires, Ricardo C. Calhelha, Lillian Barros, Eliana Pereira
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Reprogramming of arachidonic acid metabolism using α-terpineol to alleviate asthma: insights from metabolomics Food Funct. (IF 6.1) Pub Date : 2024-03-25 Ying Rong, Fanglin Liu, Hui Zhou, Tong Yu, Zhaolong Qin, Qianwen Cao, Luyao Liu, Xiaoge Ma, Lingbo Qu, Peirong Xu, Xinglin Liao, Qiman Jiang, Nan Zhang, Xia Xu
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The Role of Uterus Mitochondrial Function in High-Fat Diet-related Adverse Pregnancy Outcomes and Protection by Resveratrol Food Funct. (IF 6.1) Pub Date : 2024-03-26 Xizi Yang, Ruizhi Hu, Liping Yao, Wentao Zhang, Mingkun Shi, Jiatai Gong, Xupeng Yuan, Yanli Li, Jiahao Yan, Ying Wang, Qianjin Zhang, Ziyu He, De-Xing Hou, Zhiyong Fan, Hongfu Zhang, Liang Chen, Xi He, Jianhua He, Shusong Wu
This study aimed to elucidate the mechanism of obesity-related adverse pregnancy outcomes and further investigate the effect of resveratrol on reproductive performance in a short- or long-term HFD-induced obese mouse model. Results showed maternal weight had a significant positive correlation with litter mortality in mice. A long-term HFD increased body weight and litter mortality with decreased expression
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β-Hydroxy-β-methylbutyrate (HMB) leads to phospholipase D2 (PLD2) activation and alters circadian rhythms in myotubes Food Funct. (IF 6.1) Pub Date : 2024-03-26 Meytal Cohen-Or, Nava Chapnik, Oren Froy
β-Hydroxy-β-methylbutyrate (HMB) is a breakdown product of leucine, which promotes muscle growth. Although some studies indicate that HMB activates AKT and mTOR, others show activation of the downstream effectors, P70S6K and S6, independent of mTOR. Our aim was to study the metabolic effect of HMB around the circadian clock in order to determine more accurately the signaling pathway involved. C2C12
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Higher dose of riboflavin ameliorates intestinal inflammation via immune modulation and alterations of gut microbiota homeostasis in DSS-colitis C57BL/6 mice Food Funct. (IF 6.1) Pub Date : 2024-03-26 Wang-Wei Zhang, Kiran Thakur, Jian-Guo Zhang, Zhao-Jun Wei
While there have been advancements in understanding the direct and indirect impact of riboflavin (B2) on intestinal inflammation, the precise mechanisms are still unknown. This study focuses on evaluating the effects of riboflavin (B2) supplementation on a colitis mouse model induced by 3% dextran sodium sulphate (DSS). We administered three different doses of oral B2 (VB2L, VB2M, and VB2H) and assessed
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Litchi pulp-derived gamma-aminobutyric acid (GABA) extract counteracts liver inflammation induced by litchi thaumatin-like protein Food Funct. (IF 6.1) Pub Date : 2024-03-26 Yao Wang, Dongwei Wang, Kai Wang, Shaoquan Weng, Rongbo Zheng, Xuwei Liu, Lei Zhao, Chuyuan Li, Zhuoyan Hu
Gamma-aminobutyric acid (GABA) is the predominant amino acid in litchi pulp, known for its neuroregulatory effects and anti-inflammatory properties. Although previous research has highlighted the pro-inflammatory characteristics of litchi thaumatin-like protein (LcTLP), interplay between GABA and LcTLP in relation to inflammation remains unclear. This study aims to explore the hepatoprotective effects
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A Novel Black Poplar Propolis Extract with Remarkable Health-Promoting Properties: Focus on Chemical Composition, Antioxidant, Anti-inflammatory, and Anti-genotoxic Activities Food Funct. (IF 6.1) Pub Date : 2024-03-26 Mattia Acito, Ina Varfaj, Virginia Brighenti, Emine Ceren Cengiz, Tommaso Rondini, Cristina Fatigoni, Carla Russo, Donatella Pietrella, Federica Pellati, Desirée Bartolini, Roccaldo Sardella, Massimo Moretti, Milena Villarini
Propolis is a resinous mixture produced by honeybees, which has been used since ancient times for its useful properties. However, its chemical composition and bioactive activity may vary, depending on the geographical area of origin and the type of tree bees use for collecting pollen. In this context, this research aimed to investigate the total phenolic content (using the Folin-Ciocalteu assay) and
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Pinobanksin ameliorated DSS-induced acute colitis mainly through modulation of SLC7A11/glutathione-mediated intestinal epithelial ferroptosis Food Funct. (IF 6.1) Pub Date : 2024-03-26 Hai-Lian Bi, Shibin Guo, Yan Wang, Zhijie Liu, Guokai Wu, Xiaokui Huo, Li Guo, Huishu Guo, Yongjian Xiong
Inhibition of ferroptosis in intestinal epithelial cells serves as an attractive target for the development of therapeutic strategies for colitis. Pinobanksin, one of the main flavonoids derived from propolis, possesses significant anti-inflammatory effects and inhibits cell death of several cell lines. Here, we evaluated whether pinobanksin influenced colitis by modulation of epithelial ferroptosis
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Probiotic-fermented tomato with hepatic lipid metabolism modulation effects: analysis of physicochemical properties, bioactivities, and potential bioactive compounds Food Funct. (IF 6.1) Pub Date : 2024-03-26 Benliang Wei, Wendi Zheng, Zhen Peng, Xiao Muyan, Tao Huang, Ming-Yong Xie, Tao Xiong
Lactiplantibacillus plantarum NCUH001046 (LP)-fermented tomato exhibited the potential to alleviate obesity in our previous study. This subsequent study further delves deeper into the effects of LP fermentation on physicochemical properties, bioactivities, and hepatic lipid metabolism modulation of tomato, as well as the analysis of potential bioactive compounds exerting obesity-alleviating effects
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Encapsulation of short-chain bioactive peptides (BAPs) for gastrointestinal delivery: a review Food Funct. (IF 6.1) Pub Date : 2024-03-25 Yoni Atma, Brent S. Murray, Amin Sadeghpour, Francisco M. Goycoolea
The majority of known food peptides with high bioactivity (BAPs) such as antihypertensive, antidiabetic, antioxidant, hypocholesterolemic, anti-inflammatory and antimicrobial actions, are short-chain sequences of less than ten amino acids. These short-chain BAPs of varying natural and synthetic origin must be bioaccessible to be capable of being adsorbed systemically upon oral administration to show
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Investigating the association between inflammation mediated by mushroom consumption and mild cognitive impairment in Chinese older adults Food Funct. (IF 6.1) Pub Date : 2024-03-25 Yongbao Wei, Lili Chen, Rongyan Qiu, Bixia Wang, Jinxiu Liu, Xiuli Li, Zhaoyi Hou, Tingting Wu, Huizhen Cao, Xinli Ji, Ping Zhang, Yuping Zhan, Mianxiang Xue, Linlin Qiu, Linlin Wang, Mingfeng Chen
Background: Chronic inflammatory stimulation is a major risk factor for mild cognitive impairment. Mushroom consumption and inflammatory factors may play an important role in the pathogenesis of mild cognitive impairment. Additionally, consuming mushroom can reduce the levels of inflammatory cytokines and preserve cognitive function. Therefore, this study aimed to investigate the relationship between
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Healthy Diet Modify the Effect of High Serum Urate on Chronic Obstructive Pulmonary Disease: Results from the UK Biobank Study Food Funct. (IF 6.1) Pub Date : 2024-03-25 Tingjing Zhang, Rui Ye, Zhenfei Shen, Qing Chang, Yuhong Zhao, Liangkai Chen, Li Zhao, Yang Xia
Background: The role of serum urate (SU) levels in the development of chronic obstructive pulmonary disease (COPD) remains a topic of debate, and it is unclear whether a healthy diet can mitigate the impact of SU on COPD risk. The objective of this study is to examine whether and to what extent a healthy diet can reduce the risk of COPD in relation to SU levels. Methods: The cohort analysis included
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Dual intervention on the gut and skin microbiota attenuates facial cutaneous aging Food Funct. (IF 6.1) Pub Date : 2024-03-25 Liujing Zhang, Shun Yu, Yin Guan, Dan Wang, Ju Yang, Jingling Li, Wei Zhao, Feng Zhang
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Increased nitrate intake from beetroot juice over 4 weeks affects nitrate metabolism, but not vascular function or blood pressure in older adults with hypertension Food Funct. (IF 6.1) Pub Date : 2024-03-25 Rebeka Fejes, Martin Lutnik, Stefan Weisshaar, Nina Pilat, Karl-Heinz Wagner, Hans-Peter Stüger, Jonathan M. Peake, Richard J Woodman, Kevin Croft, Catherine Patricia Bondonno, Jonathan Hodgson, Michael Wolzt, Oliver Neubauer
The decline in vascular function and increase in blood pressure with aging contribute to an increased cardiovascular disease risk. In this randomized placebo-controlled crossover study, we evaluated whether previously reported cardiovascular benefits of plant-derived inorganic nitrate via nitric oxide (NO) translate into improved vascular function and blood pressure-lowering in 15 men and women (age
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Sugar types, genetic predictors of gut microbe, and the risk of chronic kidney disease: a prospective cohort study Food Funct. (IF 6.1) Pub Date : 2024-03-25 Gang Zheng, Yixiao zhang, Fengrong Ou, Qing Chang, Chao ji, Honghao Yang, Liangkai chen, Yang Xia, Yu-Hong Zhao
Background: Emerging studies suggest that focusing on specific types or sources of sugars may yield greater benefits in preventing chronic kidney disease (CKD). Objective: We aimed to investigate the associations between free and non-free sugar intakes and CKD risk as well as the potential sugar type-gut microbiome interactions. Methods: A total of 138,604 participants from the UK Biobank were included
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Association of dietary overall antioxidant intake with all-cause and cause-specific mortality among adults with depression: evidence from NHANES 2005-2018 Food Funct. (IF 6.1) Pub Date : 2024-03-25 Wenjie Wang, yuwei Shi, Jiakai Zhang, Yifeng Wang, therese martin cheteu wabo, Yang Yang, Wei He, shankuan zhu
Higher intakes of individual antioxidants such as vitamins A, C, and E have been linked to mortality in the general population, but the association of overall antioxidant intake with mortality especially in depressed adults remains unclear. We aimed to investigate whether dietary overall antioxidant intake is associated with all-cause and cause-specific mortality among depressed adults. This study
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Beef peptides mitigate skeletal muscle atrophy in C2C12 myotubes through protein degradation, protein synthesis, and oxidative stress pathway Food Funct. (IF 6.1) Pub Date : 2024-03-25 Hyeonjin Hur, Hye-Jin Kim, Dongheon Lee, Cheorun Jo
This study aimed to investigate the potential of beef peptides (BP) in mitigating muscle atrophy induced by dexamethasone (DEX) and to elucidate the underlying three mechanisms in vitro focusing on protein degradation, protein synthesis, and the oxidative stress pathway. Finally, the anti-atrophic effect of BP was treated to enhance through purification and isolation. BP was generated using beef loin
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Natural flavonoid hesperetin blocks amyloid β-protein fibrillogenesis, depolymerizes preformed fibrils and alleviates cytotoxicity caused by amyloids Food Funct. (IF 6.1) Pub Date : 2024-03-22 Qinchen Dong, Zhan Cui, Xinming Wu, Li Li, Fuping Lu, Fufeng Liu
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Plant-based diets, mediating biomarkers, and mortality risk among adults with diabetes or prediabetes Food Funct. (IF 6.1) Pub Date : 2024-03-22 Hao-Wei Tao, Wen-Wen Han, Fei Fang, Meng-Yuan Miao, Hong-Zhen Du, Zeng-Ning Li, Jing-Si Chen, Li-Qiang Qin, Guo-Chong Chen
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Dietary Fiber and Polyphenols from Whole Grains: Effects on Gut and Health Improvement Food Funct. (IF 6.1) Pub Date : 2024-03-22 Xun Wei, Jianhui Wang, Yaxuan Wang, Yilin Zhao, Yan Long, Bin Tan, Qing X. Li, Zhenying Dong, Xiangyuan Wan
Cereals are the main source of energy acquisition in the human diet. Compared to refined grains, whole grains retain more beneficial components, including dietary fiber, polyphenols, proteins, vitamins, and minerals. Dietary fiber and bond polyphenols (biounavailable) in cereals are important active substances that can be metabolized by gut microorganism and affect the intestinal environment. There
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Lycopene from tomatoes and tomato products exerts renoprotective effects by ameliorating oxidative stress, apoptotic, pyroptotic, fibrotic, and inflammatory injury in calcium oxalate nephrolithiasis: underlying mechanisms Food Funct. (IF 6.1) Pub Date : 2024-03-22 xiaomin gao, binwei lin, chen chen, Ziyu Fang, jinzhao yang, shuzhi wu, qing chen, Kewen Zheng, zhixian yu, yeping li, Xiaofeng Gao, Guanyang Lin, Lianguo Chen
Several mechanisms underlying nephrolithiasis, one of the most common urological diseases, involve calcium oxalate formation, including oxidative stress, inflammatory reactions, fibrosis, pyroptosis, and apoptosis. Although lycopene has strong antioxidant activity, its protective effects against CaOx-induced injury have not yet been reported. This study aimed to systematically investigate the protective
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Association of Cantonese dietary patterns with mortality risk in older Chinese: a 16-year follow-up of Guangzhou Biobank Cohort Study Food Funct. (IF 6.1) Pub Date : 2024-03-22 Ce Sun, Wei Sen Zhang, C.Q. Jiang, Ya Li Jin, Shiu Lun Au Yeung, J. Woo, Kar Keung Cheng, T.H. Lam, Lin Xu
Background: Evidence about the associations between Cantonese dietary patterns and mortality is scarce. We examined the prospective association of dietary pattern with all-cause, cancer and cardiovascular disease (CVD) mortality in older Chinese. Methods: 19,598 participants of Guangzhou Biobank Cohort Study aged 50+ years were recruited from 2003-06 and followed up until July, 2022. Diet was assessed
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Mannan-oligosaccharides promote gut microecological recovery after antibiotic disturbance Food Funct. (IF 6.1) Pub Date : 2024-03-21 Jing Chen, Jialin Yin, Heqiang Xie, Wenwei Lu, Hongchao Wang, Jianxin Zhao, Jinlin Zhu
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Sciadonic acid attenuates high-fat diet-induced bone metabolism disorders in mice Food Funct. (IF 6.1) Pub Date : 2024-03-21 Shiwei Yao, Hongling Lu, Tianhuan Zhou, Qihong Jiang, Chenkai Jiang, Wenjun Hu, Mingqian Li, Chin Ping Tan, Yongcai Feng, Qun Du, Guoxin Shen, Xingwei Xiang, Lin Chen
High-fat diet (HFD) has been associated with certain negative bone-related outcomes, such as bone metabolism disruption and bone loss. Sciadonic acid (SA), one of the main nutritional and functional components of Torreya grandis seed oil, is a unique Δ5-unsaturated-polymethylene-interrupted fatty acid (Δ5-UPIFA) that has been claimed to counteract such disorders owing to some of its physiological effects
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Spread it on thick? Relative effects of condiment addition and slice thickness on eating rate of bread Food Funct. (IF 6.1) Pub Date : 2024-03-19 Dieuwerke P. Bolhuis, Matthijs Dekker, Stefano Renzetti
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Guanidinoacetic acid ameliorates hepatic steatosis and inflammation and promotes white adipose tissue browning in middle-aged obese mice induced by a high-fat diet Food Funct. (IF 6.1) Pub Date : 2024-03-20 Yuan Su, Xinrui Li, Jiamin Zhao, Bingzhen Ji, Xiaoyi Zhao, Jinxin Feng, Junxing Zhao
Guanidinoacetic acid (GAA) is a naturally occurring amino acid derivative that plays a critical role in energy metabolism. In recent years, increasing evidence supports the importance of GAA in metabolic dysfunction. Hence, we aimed to investigate the effects of GAA on hepatic and adipose tissue metabolism, as well as systemic inflammatory responses in obese middle-aged mice models, and attempted to
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Folic acid supplementation prevents high body fat-induced bone loss through TGR5 signaling pathways Food Funct. (IF 6.1) Pub Date : 2024-03-20 Yaxi Zhang, Jieqiong Wei, Xiangling Feng, Qian Lin, Jing Deng, Yuehan Yuan, Min Li, Bingfang Zhai, Jihua Chen
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Tyrosol regulates hepatic lipid metabolism in high-fat diet-induced NAFLD mice Food Funct. (IF 6.1) Pub Date : 2024-03-20 Yu Wang, Jihang Hou, Xiaoping Li, Pan Chen, Fang Chen, Yao Pan, Zeyuan Deng, Jing Li, Rong Liu, Ting Luo
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α acid fraction from Hop extract exerts an endothelium-derived hyperpolarization vasorelaxant effect through TRPV4 employing the feedforward mechanism of PKCα Food Funct. (IF 6.1) Pub Date : 2024-03-20 Paola Di Pietro, Emanuela Salviati, Antonio Damato, Valeria Prete, Angela Carmelita Abate, Pietro Campiglia, Carmine Vecchione, Eduardo Sommella, Albino Carrizzo
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Olive oil intake and cardiovascular disease, cancer, and all-cause mortality: a systematic review and dose–response meta-analysis of prospective cohort studies Food Funct. (IF 6.1) Pub Date : 2024-03-20 Yamin Ke, Haohao Fan, Yang Zhao, Xueru Fu, Mengmeng Wang, Yajuan Gao, Yaobing Chen, Weifeng Huo, Wenkai Zhang, Longkang Wang, Yuying Wu, Xi Li, Dongdong Zhang, Fulan Hu, Ming Zhang, Liang Sun, Jie Lu, dongsheng Hu
Background: Currently, the reported links between olive oil intake, cardiovascular disease (CVD) and cancer morbidity and mortality, and all-cause mortality are inconsistent. The aim of this meta-analysis is to synthesize the reported correlations of olive oil intake with CVD, coronary heart disease (CHD), stroke and cancer incidence and mortality, and all-cause mortality. Methods: PubMed, Embase,
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Structure characteristics, protective effect and mechanisms of ethanol-fractional polysaccharides from Dendrobium officinale on acute ethanol-induced gastritis Food Funct. (IF 6.1) Pub Date : 2024-03-20 Hua Zhu, Lei Xu, Peng Chen, Zhenhao Li, Wujin Yu, Peilong Sun, Jian-Yong Wu, Ming Cai
Gastritis is a common disease characterized by gastric ulcer and more severe bleeding. Daily intake of large amounts of alcohol can cause acute gastritis, which brings inconvenience to people's lives. This study aims to explore the protective effects of different ethanol-fractional polysaccharides of Dendrobium officinale (EPDO) on acute alcohol-induced gastric injury in vivo. Results showed that EPDO-80
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The Causal Association between Artificial Sweeteners and the Risk of Cancer: A Mendelian randomization study Food Funct. (IF 6.1) Pub Date : 2024-03-19 Haotian Pan, Chenchen Feng, Ziting Zhou, Jiamin Huang, Jiasi Deng, Yuanyuan Zhou, Xinru Mu, Yuxuan Wang, Qian Wang, Ke Wang, Zhigang Lu
Artificial sweeteners (AS) have been widely added to food and beverages because of their properties of low calorie but the saved taste of sweet. However, if the consumption of AS is causally associated with cancer risk is not clear. Here we utilized the two-sample Mendelian randomization (MR) method to study the potentially causal association. Genetic variants like single-nucleotide polymorphisms (SNPs)
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Theabrownin from Fu Brick Tea Ameliorates High-fat Induced Insulin Resistance, Hepatic Steatosis, and Inflammation in Mice by Altering the Composition and Metabolites of Gut Microbiota Food Funct. (IF 6.1) Pub Date : 2024-03-19 Zhongting Lu, Yan Zheng, Juan Zheng, Qijian Liang, Qingcai Zhen, Mengjie Cui, Haoru Yang, Haotian Wu, Cuixia Tian, Kangming Zhu, Chunyong Bian, Lei Du, Hao Wu, Xin Guo
Fu Brick tea belongs to fermented dark tea, which is one of the six categories of tea. Fu Brick tea has been reported to reduce adiposity and has beneficial effects for hypercholesterolemia and cardiovascular disease. Theabrownin (TB) is one of the pigments with the most abundant content in Fu Brick tea. TB has also been reported to have lipid-lowering effects, but its mechanism remains unclear. We
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Fucoxanthin restructures gut microbiota and metabolic functions of non-obese individuals in an in-vitro fermentation model Food Funct. (IF 6.1) Pub Date : 2024-03-19 Bingbing Guo, Weihao Zhang, Yonghui Zhou, Jingyi Zhang, Cheng-Chu Zeng, Peipei Sun, Bin Liu
Fucoxanthin, a carotenoids exclusively derived from algae, exerts its bioactivities with modulation of gut microbiota in mice. However, the mechanisms through which fucoxanthin regulates the gut microbiota and its derived metabolites/metabolism in human remian unclear. This study investigated the effects of fucoxanthin on gut microbiota and metabolism of non-obese individuals using an in-vitro simulated
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Cordyceps sinensis accelerates stem cell recruitment to human skeletal muscle after exercise Food Funct. (IF 6.1) Pub Date : 2024-03-18 Luthfia Dewi, Wei-Horng Jean, Kun-Chin Huang, Chih-Yang Huang, Liang-Kung Chen, Yu-Chieh Liao, Andrew Nicholls, Li-Fan Lai, Chia-Hua Kuo
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Long-term intake of thermo-induced oxidized oil results in anxiety-like and depression-like behaviors: involvement of microglia and astrocytes Food Funct. (IF 6.1) Pub Date : 2024-03-19 Meishan Lu, Jiachen Shi, Xue Li, Yanjun Liu, Yuanfa Liu
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In vitro study of the blood–brain barrier transport of bioactives from Mediterranean foods Food Funct. (IF 6.1) Pub Date : 2024-03-18 Marta Gallardo-Fernandez, Ana Rita Garcia, Ruth Hornedo-Ortega, Ana M. Troncoso, M. Carmen Garcia-Parrilla, M. Alexandra Brito
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Fasting mimicking diet extends lifespan, improves intestinal and cognitional health Food Funct. (IF 6.1) Pub Date : 2024-03-18 Qingyi Wang, Jilei Xu, Man Luo, Yao Jiang, Yanrou Gu, Qiwen Wang, Jiamin He, Yong Sun, Yifeng Lin, Lijun Feng, Shujie Chen, Tongyao Hou
Caloric restriction is an effective means of extending a healthy lifespan. Fasting mimicking diet (FMD) is a rising pattern of caloric restriction. We found that FMD significantly prolonged the lifespan in prematurely aging mice. In naturally aging mice, FMD improved cognitional and intestinal health. Through a series of behavioral experiments, we found that FMD relieved anxiety and enhanced cognition
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The association between raw garlic consumption and risk of depressive symptoms: the TCLSIH Cohort study Food Funct. (IF 6.1) Pub Date : 2024-03-16 Yaxiao Wang, Jiaoyang Li, LI Li, Shengxin Quan, Ge Meng, Yeqing Gu, Qing Zhang, Li Liu, Hongmei Wu, Sizhen Lai, Yinxiao Chen, Tongfeng Liu, Shaomei Sun, Xing Wang, Qiyu Jia, Kun Song, Kaijun Niu
Background:Garlic has antioxidant, anti-inflammatory, cardiovascular improvement and other beneficial effects on human health. However, few studies have evaluated the association of garlic intake with the risk of depressive symptoms. The aim of this prospective cohort was to examine the association between the frequency of raw garlic consumption and depressive symptoms in the general adult population
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Correction: Mechanisms of the ethanol extract of Gelidium amansii for slow aging in high-fat male Drosophila by metabolomic analysis Food Funct. (IF 6.1) Pub Date : 2024-03-15 Yushi Chen, Qisheng Wang, Haitao Luo, Shanggui Deng, Yongqi Tian, Shaoyun Wang
Correction for ‘Mechanisms of the ethanol extract of Gelidium amansii for slow aging in high-fat male Drosophila by metabolomic analysis’ by Yushi Chen et al., Food Funct., 2022, 13, 10110–10120, https://doi.org/10.1039/D2FO02116A.
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Characterisation and beneficial effects of a Lupinus angustifolius protein hydrolysate obtained by immobilisation of the enzyme alcalase® Food Funct. (IF 6.1) Pub Date : 2024-03-15 Guillermo Santos-Sánchez, Ivan Cruz-Chamorro, José Carlos Márquez-López, Justo Pedroche, Ana Isabel Álvarez-López, María del Carmen Millán-Linares, Patricia Judith Lardone, Antonio Carrillo-Vico
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Peanuts Supplementation Affects Compositions and Functions of Gut Microbiome in Ugandan Children Food Funct. (IF 6.1) Pub Date : 2024-03-15 Jia-Sheng Wang, Kathy Xue, Zilin Li, John Ssempebwa, Geofrey Musinguzi, Gakenia Wamuyu-Maina, Jamie Rhoads, Dave Hoisington, Lili Tang
Childhood malnutrition remains a serious global health concern, particularly in low-income nations like Uganda. This study investigated the impact of peanut supplementation on compositions and functions of gut microbiome with nutritional improvement. School children aged 6-9 years from four rural communities were recruited, with half receiving roasted peanut snacks while the other half served as controls
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Restorative effects of (+)-epicatechin in a rodent model of aging induced muscle atrophy: underlying mechanisms Food Funct. (IF 6.1) Pub Date : 2024-03-15 Israel Ramirez-Sanchez, Viridiana Navarrete-Yañez, Lucia Ramirez, Leonor Galera, Enrique Mendez-Bolaina, Veronica Najera, Guillermo Ceballos, Francisco Villarreal
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Bifidobacterium longum GL001 alleviates rat intestinal ischemia–reperfusion injury by modulating gut microbiota composition and intestinal tissue metabolism Food Funct. (IF 6.1) Pub Date : 2024-03-15 Jilang Tang, Mingchao Zhao, Xue Miao, Hong Chen, Binger Zhao, Yingying Wang, Yingchao Guo, Tiantian Wang, Xin Cheng, Hongri Ruan, Jiantao Zhang
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Ameliorative effect of bound polyphenols in mung bean coat dietary fiber on DSS-induced ulcerative colitis in mice: the intestinal barrier and intestinal flora Food Funct. (IF 6.1) Pub Date : 2024-03-14 Tianxiang Ao, Hairong Huang, Bing Zheng, Yi Chen, Jianhua Xie, Xiaobo Hu, Qiang Yu
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Tropical postbiotics alleviate the disorders in the gut microbiota and kidney damage induced by ochratoxin A exposure Food Funct. (IF 6.1) Pub Date : 2024-03-14 Shuaiming Jiang, Lingwei Du, Qian Zhao, Shunyong Su, Shi Huang, Jiachao Zhang
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Maillard-type glycated collagen with alginate oligosaccharide suppresses inflammation and oxidative stress by attenuating the expression of LPS receptors Tlr4 and Cd14 in macrophages Food Funct. (IF 6.1) Pub Date : 2024-03-14 Boxue Yang, Wenzhao Li, Hiroki Saeki, Yutaka Shimizu, Ga-Hyun Joe
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Effects of quercetin on the DNA methylation pattern in tumor therapy: an updated review Food Funct. (IF 6.1) Pub Date : 2024-03-14 Qin Wang, Chen Ma, Nan Wang, Huixian Mao
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Tryptophan Metabolites Relieve Intestinal Candida Albicans Infection by Altering the Gut Microbiota to Reduce IL-22 Release from Group 3 Innate Lymphoid Cells of the Colon Lamina Propria Food Funct. (IF 6.1) Pub Date : 2024-03-13 Ziyao Peng, Jiali Zhang, Meng Zhang, Liping Yin, Ziyang Zhou, Cuiting Lv, Zetian Wang, Jianguo Tang
Invasive candidiasis may be caused by Candida albicans (C. albicans) colonization of the intestinal tract. Therefore, preventing intestinal damage caused by C. albicans infection and protecting intestinal barrier function have become an important problem to be solved. Integrated analyses of microbiome with metabolome revealed a remarkable shift of gut microbiota and tryptophan metabolites, kynurenic
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Stored white tea ameliorates DSS-induced ulcerative colitis in mice by modulating the composition of the gut microbiota and intestinal metabolites Food Funct. (IF 6.1) Pub Date : 2024-03-13 Zhiyuan Lin, Weidong Dai, Shanshan Hu, Dan Chen, Han Yan, Liang Zeng, Zhi Lin
Changes in the chemical composition of white tea during storage have been studied extensively; however, whether such chemical changes impact the efficacy of white tea in ameliorating colitis remains unclear. In this study, we compared the effects of new (2021 WP) and 10-year-old (2011 WP) white tea on 3% dextrose sodium sulfate (DSS)-induced ulcerative colitis in mice by gavaging mice with the extracts
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Changes in the structural, physicochemical and functional properties and in vitro fecal fermentation characteristics of barley dietary fiber fermented by Lactiplantibacillus plantarum dy-1 Food Funct. (IF 6.1) Pub Date : 2024-03-13 Xiang Xiao, Xiaodong Li, Juan Bai, Songtao Fan, Maria Daglia, Jiaying Li, Yiwei Ding, Yanshun Zhang, Yansheng Zhao
Fermentation is an effective method for improving the nutritional quality and functional characteristics of grains. This study investigated changes in the structural, physicochemical, and functional properties of fermented barley dietary fiber (FBDF) exerted by Lactiplantibacillus plantarum dy-1 (Lp. plantarum dy-1) as well as its in vitro fecal fermentation characteristics. Lp. plantarum dy-1 fermentation
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Molecular networking-guided investigation of the secondary metabolome of four Morus species and their in vivo neuroprotective potential for the mitigation of Alzheimer's disease Food Funct. (IF 6.1) Pub Date : 2024-03-13 Nesrine M. Hegazi, Tarik A. Mohamed, Abeer Salama, Ahmed R. Hamed, Hamada H. Saad, Ibrahim A. Saleh, Eman H. Reda, Ahmed A. A. Elsayed, Mahmoud A. A. Ibrahim, Paul W. Paré, Thomas Efferth, Mohamed-Elamir F. Hegazy
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Aflatoxin B1 exposure causes splenic pyroptosis by disturbing the gut microbiota-immune axis Food Funct. (IF 6.1) Pub Date : 2024-03-12 Huodai Chen, Lin Ye, Yurun Wang, Jiahong Chen, Jie Wang, Xueling Li, Hongtao Lei, Yunle Liu
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Improvement of hepatic innate immunity in chemically-injured livers to develop hepatocarcinoma by a serine type-protease inhibitors enriched extract from Chenopodium quinoa Food Funct. (IF 6.1) Pub Date : 2024-03-12 Maria Alicia Rueda Huélamo, Alba Martínez Perlado, Valeria Consoli, Aurora García-Tejedor, Claudia Monika Haros, José Moisés Laparra Llopis
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Oral administration of egg ovalbumin allergen induces dysregulation of tryptophan metabolism in sensitized Balb/c mice Food Funct. (IF 6.1) Pub Date : 2024-03-12 Zhongliang Wang, Jie Zhang, Jin Yuan, Fangfang Min, Jinyan Gao, Wenfeng Liu, Meijia Huang, Yong Wu, Hongbing Chen
Food allergy (FA), triggered by specific dietary allergens, has emerged as a substantial global concern for food safety and public health. While studies have elucidated changes in immune cells and cytokines associated with allergen exposure, a comprehensive analysis of the host's metabolic features and the interaction between metabolites and the gut microbiota has not been conducted. In this study
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Exopolysaccharide production by Lactobacillus plantarum T10 is responsible for the probiotic activity in enhancing intestinal barrier function in vitro and in vivo Food Funct. (IF 6.1) Pub Date : 2024-03-07 Ting Tao, Li Zhang, Tianfei Yu, Jiaxue Ma, Shuang Lu, Jing Ren, Xiangyu Li, Xiaohua Guo
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Lactobacillus reuteri's multifaceted role in mitigating ionizing radiation-induced injury in Drosophila melanogaster Food Funct. (IF 6.1) Pub Date : 2024-03-11 Songling Zhang, Zhaoyu Wang, Jin Jiang, Guoxing Feng, Saijun Fan
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Se-methylselenocysteine ameliorates mitochondrial function by targeting both mitophagy and autophagy in the mouse model of Alzheimer's disease Food Funct. (IF 6.1) Pub Date : 2024-03-12 Yongli Xie, Xiaoshan Ke, Zhencong Ye, Xuexia Li, Zetao Chen, Jiantao Liu, Ziyi Wu, Qiong Liu, Xiubo Du
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New neuroprotective derivatives of cinnamic acid by biotransformation Food Funct. (IF 6.1) Pub Date : 2024-03-12 Hadeer Elkharsawy, Ramadan A. Eldomany, Amira Mira, Amal F. Soliman, Mohamed Amir, Saleh El-sharkawy