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Secondary hypertension due to a juxtaglomerular cell tumor
Journal of the American Society of Hypertension Pub Date : 2018-06-07 , DOI: 10.1016/j.jash.2018.05.005
Igor Nunes , Tiago Santos , Joana Tavares , Lurdes Correia , João Coutinho , J.M. Braz Nogueira , Leonor Carvalho , J.L. Ducla Soares

Juxtaglomerular cell tumors are rare, generally benign, and they are one of the secondary surgically treatable causes of arterial hypertension. There are about 100 reported cases on literature, and the diagnosis is usually carried out based on a high clinic suspicion index, mostly in patients with hypokalemia and arterial hypertension. The diagnosis involves blood tests and imaging studies, but it is only definite with histopathological exam after surgical treatment. We present a case of a 22-year-old woman with resistant arterial hypertension and renal and cardiovascular target-organ lesions. High plasmatic renin and a nodular renal mass on magnetic resonance imaging were present. A tumorectomy was performed and the histological exam confirmed a reninoma. After surgery, blood pressure and serum renin values returned to normal without medication. This work focuses on the need to exclude rare secondary causes of hypertension in young patients with resistant forms of this disease.



中文翻译:

邻近肾小球细胞瘤引起的继发性高血压

肾小球细胞瘤很少见,通常是良性的,并且是动脉高压的第二个可手术治疗的原因之一。文献报道的病例约有100例,通常基于较高的临床怀疑指数进行诊断,主要是在低钾血症和动脉高血压患者中进行。诊断涉及血液检查和影像学检查,但只有在手术治疗后进行组织病理学检查才能明确诊断。我们介绍了一例22岁的女性,患有抗药性动脉高压以及肾脏和心血管靶器官损害。磁共振成像显示血浆血浆肾素高和结节性肾结节。进行了肿瘤切除并且组织学检查证实了肾素瘤。手术后,无需药物治疗,血压和血清肾素值恢复正常。

更新日期:2018-06-07
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