Researchers have speculated that sedentary behaviour may reduce health-related quality of life (HRQOL), but the extent to which this is true remains unknown. Our study sought to systematically review and synthesise research on the relationship between sedentary behaviours and HRQOL and to investigate if these relationships are moderated by age, health status, and HRQOL domain. The review was registered with PROSPERO (no. CRD42016036342). We searched six electronic databases. The selection process resulted in including k = 27 original studies; k = 18 were included in a meta-analysis. Data were synthesised twice, using the methods of systematic review and meta-analysis, in order to reduce biases related to a small number of included studies. Both the systematic review and meta-analytical methods indicated that lower levels of sedentary behaviours were associated with higher physical HRQOL (estimate of average effect: r = −.140; 95% CI −.191, −.088). Moderator analyses indicated that associations between the physical HRQOL domain and sedentary behaviours may be similar in strength across age- and health status groups. Causal inferences could not be drawn as most studies were cross-sectional. Concluding, sedentary behaviours were related to better physical HRQOL but not reliably to mental and social HRQOL.

中文翻译：

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久坐的行为和与健康有关的生活质量。系统评价和荟萃分析

研究人员推测，久坐的行为可能会降低与健康有关的生活质量（HRQOL），但这种情况的真实性尚不清楚。我们的研究旨在系统地回顾和综合研究久坐行为与HRQOL之间的关系，并调查这些关系是否受年龄，健康状况和HRQOL域的调节。该评论已在PROSPERO注册（编号CRD42016036342）。我们搜索了六个电子数据库。选择过程包括k  = 27项原始研究；ķ 荟萃分析中包括18例患者。为了减少与少数纳入研究相关的偏见，使用系统综述和荟萃分析的方法对数据进行了两次合成。系统评价和荟萃分析方法均表明，久坐行为水平较低与较高的身体HRQOL相关（平均影响估计值：r  = -.140； 95％CI -.191，-.088）。主持人的分析表明，在不同年龄和健康状况的人群中，身体HRQOL域与久坐行为之间的关联在强度上可能相似。由于大多数研究都是横断面的，因此无法得出因果推论。最后，久坐的行为与更好的身体HRQOL有关​​，但与精神和社会HRQOL不可靠相关。