The beneficial effects of nonpolar DHA/EPA in triacylglycerol (TG) and ethyl ester (EE) forms as well as terrestrial phospholipids on physical fatigue have been widely reported. However, the results involving the effects were inconsistent, and the reason might be that the differences in physical fatigue induced by aerobic and anaerobic exercises were usually ignored. In addition, it has been reported the significant improvement of DHA/EPA esterified to phospholipids (DHA/EPA-PLs) on many fields but not physical fatigue. Therefore, the effects of DHA/EPA-PLs on physical fatigue induced by aerobic and anaerobic exercises were evaluated and compared with those of l-carnitine and astaxanthin using swimming and running exhaustion tests in mice, respectively. The results indicated that DHA/EPA-PLs and l-carnitine have significant effects on the performance of aerobic exercise, while astaxanthin had remarkable effects on the performance of anaerobic exercise. The possible underlying mechanisms indicated that DHA/EPA-PLs significantly promoted the carbohydrate and lipid metabolism as well as the mitochondrial respiratory chain and tricarboxylic acid cycle in muscles. The study presented a potential novel candidate or targeted dietary patterns for alleviating physical fatigue.

中文翻译：

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富含DHA / EPA的磷脂对小鼠有氧和无氧运动影响的初步研究。

已经广泛报道了非极性DHA / EPA以三酰基甘油（TG）和乙基酯（EE）的形式以及陆地磷脂对身体疲劳的有益作用。但是，涉及效果的结果不一致，原因可能是有氧和无氧运动引起的身体疲劳差异通常被忽略。另外，已经报道了在许多领域中酯化为磷脂（DHA / EPA-PL）的DHA / EPA的显着改善，但没有身体疲劳。因此，分别评估了DHA / EPA-PLs对有氧运动和厌氧运动引起的身体疲劳的影响，并分别在小鼠的游泳和跑步力竭测试中将其与左旋肉碱和虾青素进行了比较。结果表明，DHA / EPA-PLs和左旋肉碱对有氧运动表现有显着影响，而虾青素对无氧运动表现有显着影响。可能的潜在机制表明DHA / EPA-PLs显着促进了肌肉中的碳水化合物和脂质代谢以及线粒体呼吸链和三羧酸循环。这项研究提出了减轻身体疲劳的潜在新的候选或目标饮食模式。