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No Zones Left Behind: Democratic Hepatocytes Contribute to Liver Homeostasis and Repair.
Cell Stem Cell ( IF 23.9 ) Pub Date : 2020-01-02 , DOI: 10.1016/j.stem.2019.12.002
Satdarshan P Monga 1
Affiliation  

Despite minimal turnover, liver cells possess immense regenerative capacity. Some studies suggest existence of a hepatocyte subset with such unique capabilities. However, in the current issue of Cell Stem Cell, three independent studies (Chen et al., 2020; Matsumoto et al., 2020, and Sun et al., 2020) demonstrate an equitable homeostatic and reparative potential of all hepatocytes, irrespective of their lobular location or ploidy status.

中文翻译:

没有留下任何区域:民主的肝细胞有助于肝脏的稳态和修复。

尽管周转率最低,但肝细胞具有巨大的再生能力。一些研究表明存在具有这种独特功能的肝细胞亚群。然而,在本期《细胞干细胞》中,三项独立研究(Chen等,2020; Matsumoto等,2020和Sun等,2020)证明了所有肝细胞具有均等的体内平衡和修复潜能。它们的小叶位置或倍性状态。
更新日期:2020-01-02
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