The S. aureus bacterium is surrounded by capsular polysaccharides. These capsular polysaccharides are important in the pathogenesis of staphylococcal infection. There are 11 serotypes of capsular polysaccharides that have been identified, and a majority of strains express capsular polysaccharides type 5 (CP5) or 8 (CP8). The main focus of this review is to describe recent advances in the area of the chemical synthesis of monosaccharide components of S. aureus CP, oligosaccharide assembly and functionalization. Chemical routes to obtain oligosaccharides derived from CP1, CP5 and CP8 represent a compendium of modern classics of the total synthesis of challenging glycan sequences.

中文翻译：

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金黄色葡萄球菌荚膜多糖：结构和合成的观点。

金黄色葡萄球菌被荚膜多糖包围。这些荚膜多糖在葡萄球菌感染的发病机理中很重要。已经鉴定出11种血清型荚膜多糖，大多数菌株表达5型（CP5）或8型（CP8）荚膜多糖。这篇综述的主要焦点是描述金黄色葡萄球菌CP的单糖组分的化学合成，寡糖组装和功能化方面的最新进展。获得衍生自CP1，CP5和CP8的寡糖的化学路线代表了具有挑战性的聚糖序列总合成的现代经典之作。