Erosive lichen planus of the vulva (ELPV) is a subtype of lichen planus characterized by desquamative, erosive dermatitis involving the vulva and vagina. Management of ELPV is challenging; almost 25% of patients have ELPV that is resistant to first-line therapy with topical corticosteroids.^1,2 There are very few studies of ELPV, which makes management of recalcitrant ELPV difficult. Specifically, little evidence is available on methotrexate (MTX) for the treatment of recalcitrant ELPV. The aim of this study was to retrospectively review medical records to evaluate the efficacy of treatment with MTX in women with ELPV at a vulvar clinic.

中文翻译：

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甲氨蝶呤用于治疗顽固性外阴糜烂性扁平苔藓。

外阴糜烂性扁平苔藓（ELPV）是扁平苔藓的一种亚型，其特征是涉及外阴和阴道的脱屑性糜烂性皮炎。ELPV的管理充满挑战；几乎25％的患者具有局部用皮质类固醇激素抵抗一线治疗的耐药性。^{1 ，2}有ELPV，这使得顽固ELPV的管理难度非常少数的研究。具体而言，关于甲氨蝶呤（MTX）用于治疗顽固性ELPV的证据很少。这项研究的目的是回顾性审查医疗记录，以评估外阴诊所接受ELPV的妇女使用MTX的疗效。