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Surveillance in Patients With Diffuse Large B Cell Lymphoma.
Mayo Clinic Proceedings ( IF 8.9 ) Pub Date : 2020-01-01 , DOI: 10.1016/j.mayocp.2019.05.011
Avyakta Kallam 1 , Jayanth Adusumalli 2 , James O Armitage 1
Affiliation  

With improvement in the cure rates for diffuse large B cell lymphoma, the question of surveillance imaging in patients who achieve complete remission after the initial therapy has become relevant. Some of the clinical practice guidelines recommend surveillance scanning. However, several studies have reported no benefit in overall survival with scans. Moreover, studies have highlighted an increased risk for developing secondary malignancies because of exposure to ionizing radiation from the scans. Different international societies have contrasting guidelines for the role of surveillance computerized tomography scans in patients who achieve complete remission after first-line therapy. Any benefit of surveillance imaging must be balanced by the costs, risk of radiation exposure, and lack of survival benefit. The PubMed platform was searched using relevant keywords for English-language articles with no date restrictions. Search terms were cross-referenced with review articles, and additional articles were identified by manually searching reference lists. Results were reviewed by the authors and selected for inclusion based on relevance. We present a review of this current data available for surveillance imaging in patients with diffuse large B cell lymphoma.

中文翻译:

弥漫性大B细胞淋巴瘤患者的监测。

随着弥散性大B细胞淋巴瘤治愈率的提高,在初始治疗后达到完全缓解的患者进行监视成像的问题已变得很重要。一些临床实践指南建议进行监视扫描。但是,一些研究报告称,扫描对整体生存没有益处。此外,研究表明,由于暴露于扫描电离辐射中,继发恶性肿瘤的风险增加。对于一线治疗后完全缓解的患者,不同的国际社会对于计算机断层扫描监视的作用有不同的指导原则。监视成像的任何好处都必须在成本,辐射风险和缺乏生存利益之间进行权衡。使用相关关键字搜索了PubMed平台,以搜索无日期限制的英语文章。搜索词与评论文章进行了交叉引用,而其他文章则通过手动搜索参考列表进行标识。作者对结果进行了审查,并根据相关性选择纳入。我们目前对可用于弥漫性大B细胞淋巴瘤患者的监视成像的当前数据进行综述。
更新日期:2020-01-02
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