CD49f (integrin α6) is a useful marker for minimal residual disease (MRD) detection in B lymphoblastic leukemia and has recently been suggested to mediate infiltration of the central nervous system by leukemic B lymphoblasts. However, data regarding expression of CD49f protein in B lymphoblastic leukemia are limited, and whether CD49f protein expression varies among genetic subgroups of B lymphoblastic leukemia is unknown.

中文翻译：

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CD49f 蛋白表达在 B 淋巴细胞白血病的遗传亚组中有所不同，并且在 KMT2A 重排病例中明显较低

CD49f（整合素 α6）是 B 淋巴细胞白血病微小残留病 (MRD) 检测的有用标记物，最近被建议介导白血病 B 淋巴细胞对中枢神经系统的浸润。然而，关于 CD49f 蛋白在 B 淋巴细胞白血病中表达的数据是有限的，并且 CD49f 蛋白表达是否在 B 淋巴细胞白血病的遗传亚组之间存在差异尚不清楚。