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Resolution of pathogenic R-loops rescues motor neuron degeneration in spinal muscular atrophy.
Brain ( IF 14.5 ) Pub Date : 2019-01-01 , DOI: 10.1093/brain/awz394
Niko Hensel 1, 2 , Nora Tula Detering 1, 2 , Lisa Marie Walter 1, 2 , Peter Claus 1, 2
Affiliation  

This scientific commentary refers to ‘ZPR1 prevents R-loop accumulation, upregulates SMN2 expression and rescues spinal muscular atrophy’, by Kannan et al. (doi: 10.1093/brain/awz373).

中文翻译:

病原性R环的解决可以挽救脊髓性肌萎缩症中的运动神经元变性。

Kannan等人的这项科学评论提到“ ZPR1防止R环积累,上调SMN2表达并挽救脊髓性肌萎缩”。(doi:10.1093 / brain / awz373)。
更新日期:2019-12-31
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