BACKGROUND Ganglioneuromas (GNs) are composed of mature ganglion cells and Schwann cells with a fibrous stroma; GNs are most often observed in children and young adults. The majority of non-cranial GNs are located in the retroperitoneum and posterior mediastinum. Other reported rare sites include the adrenal gland, small intestine, colon and urinary bladder. However, para-testicular GNs are even more rare. CASE PRESENTATION Herein, we report the case of a patient with concurrent adrenal GN and thyroid papillary carcinoma who developed paratesticular GN eighteen years later. CONCLUSIONS We conclude that there is an association among papillary thyroid carcinoma, GN and MEN2 syndromes. This case report may provide important information for the proposed association. However, further studies are required.

中文翻译：

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并发肾上腺神经节神经瘤和甲状腺乳头状癌后18年发生睾丸副神经节神经瘤-病例报告。

背景神经节神经瘤（GNs）由成熟的神经节细胞和具有纤维基质的雪旺氏细胞组成。GNs最常见于儿童和年轻人。大多数非颅GNs位于腹膜后和纵隔后。其他报道的罕见部位包括肾上腺，小肠，结肠和膀胱。但是，睾丸旁的GN更为罕见。病例表述在此，我们报道18年前发展为睾丸旁GN的并发肾上腺GN和甲状腺乳头状癌的患者。结论我们得出结论，甲状腺乳头状癌，GN和MEN2综合征之间存在关联。该病例报告可能为提议的协会提供重要信息。但是，还需要进一步的研究。