Biodegradable polylactide (PLA) and its copolymers with shape memory properties have attracted great interests because of their important application prospects in biomedical field. In this study, random poly(L‐lactide‐co‐trimethylene carbonate‐co‐ε‐caprolactone) (LTCL) terpolymers with different molar ratio were synthesized and characterized. Monomer ε‐caprolactone (ε‐CL) was used in this study instead of glycolide in preliminary study of LTG terpolymers to investigate the transition temperature and the shape memory performance. Characterization on crystallization, mechanical properties, shape fixing, and recovery ratios of the terpolymers was conducted to investigate the correlation between crystallization and shape memory performance of LTCL terpolymers. The results are consistent with the formation of crystallized LLA segments, which could act as crosslinks, strengthened the stationary phase within the polymer matrix, and significantly improved the shape memory performance of LTCL terpolymers. For example, LTCL801010 is a crystalline polymer with high shape fixity and shape recovery ratio; its shape recovery temperature is 39°C. LTCL terpolymers with high CL content do not show shape memory performance for the rubbery at room temperature. Based on this study, PLA materials with shape memory property can be designed through the selection of monomers or the adjustment of comonomer ratio. These polymers with recovery temperature close to 37°C are expected to be used in human body such as scaffolds in tissue engineering.

中文翻译：

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LLA，TMC和ε-CL三元共聚物的形状记忆聚合物的合成和性能

具有形状记忆特性的可生物降解的聚丙交酯（PLA）及其共聚物由于在生物医学领域的重要应用前景而引起了人们的极大兴趣。在这项研究中，合成和表征了具有不同摩尔比的无规聚（L-丙交酯-共-三亚甲基碳酸酯-共-ε-己内酯）（LTCL）三元共聚物。在LTG三元共聚物的初步研究中，使用单体ε-己内酯（ε-CL）代替乙交酯来研究转变温度和形状记忆性能。对三元共聚物的结晶，机械性能，形状固定和回收率进行了表征，以研究LTCL三元共聚物的结晶与形状记忆性能之间的相关性。结果与结晶的LLA片段的形成一致，它可以充当交联键，增强聚合物基质内的固定相，并显着提高LTCL三元共聚物的形状记忆性能。例如，LTCL801010是具有高形状固定性和形状恢复率的结晶聚合物；其形状恢复温度为39°C。CL含量高的LTCL三元共聚物在室温下不显示橡胶状的形状记忆性能。根据这项研究，可以通过选择单体或调节共聚单体比例来设计具有形状记忆特性的PLA材料。这些具有接近37℃的恢复温度的聚合物有望用于人体，例如组织工程中的支架。例如，LTCL801010是具有高形状固定性和形状恢复率的结晶聚合物；其形状恢复温度为39°C。CL含量高的LTCL三元共聚物在室温下不显示橡胶状的形状记忆性能。根据这项研究，可以通过选择单体或调节共聚单体比例来设计具有形状记忆特性的PLA材料。这些具有接近37℃的恢复温度的聚合物有望用于人体，例如组织工程中的支架。例如，LTCL801010是具有高形状固定性和形状恢复率的结晶聚合物；其形状恢复温度为39°C。CL含量高的LTCL三元共聚物在室温下不显示橡胶状的形状记忆性能。根据这项研究，可以通过选择单体或调节共聚单体比例来设计具有形状记忆特性的PLA材料。这些具有接近37℃的恢复温度的聚合物有望用于人体，例如组织工程中的支架。具有形状记忆特性的PLA材料可以通过选择单体或调节共聚单体比例来设计。这些具有接近37℃的恢复温度的聚合物有望用于人体，例如组织工程中的支架。具有形状记忆特性的PLA材料可以通过选择单体或调节共聚单体比例来设计。这些具有接近37℃的恢复温度的聚合物有望用于人体，例如组织工程中的支架。