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The role of diosgenin in diabetes and diabetic complications.
The Journal of Steroid Biochemistry and Molecular Biology ( IF 4.1 ) Pub Date : 2019-12-30 , DOI: 10.1016/j.jsbmb.2019.105575
Qingxia Gan 1 , Jin Wang 1 , Ju Hu 1 , Guanhua Lou 1 , Haijun Xiong 1 , Chengyi Peng 1 , Song Zheng 2 , Qinwan Huang 3
Affiliation  

Diabetes mellitus is a chronic and common metabolic disease that seriously endangers human health. Hyperglycemia and long-term metabolic disorders in diabetes will cause damage to the whole body tissues and organs, resulting in serious complications. Nowadays, drugs for treating diabetes on the market has strong side effects, new treatments thus are urgently needed. Natural therapy of natural ingredients is a promising avenue, this is because natural ingredients are safer and they also show strong activity in the treatment of diabetes. Diosgenin is such a very biologically active natural steroidal sapogenin. The research of diosgenin in the treatment of diabetes and its complications has been widely reported. This article reviews the effects of diosgenin through multiple targets and multiple pathways in diabetes and its complications which including diabetic nephropathy, diabetic liver disease, diabetic neuropathy, diabetic vascular disease, diabetic cardiomyopathy, diabetic reproductive dysfunction, and diabetic eye disease.

中文翻译:

薯gen皂素在糖尿病和糖尿病并发症中的作用。

糖尿病是一种严重危害人类健康的慢性和常见代谢性疾病。糖尿病中的高血糖症和长期代谢紊乱会损害全身组织和器官,导致严重的并发症。如今,市场上用于治疗糖尿病的药物具有很强的副作用,因此迫切需要新的治疗方法。天然成分的自然疗法是一个有前途的途径,这是因为天然成分更安全,并且在糖尿病治疗中也显示出强大的活性。薯gen皂素是一种具有非常高生物活性的天然甾体皂甙元。薯gen皂苷元治疗糖尿病及其并发症的研究已被广泛报道。
更新日期:2019-12-30
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