BACKGROUND This study aimed to determine the association between chronic periodontitis (CP) and community-acquired pneumonia (CAP) according to CP severity in the Korean population based on the National Health Insurance Service database. METHODS Data from the National Health Insurance Service-National Health Screening Cohort (NHIS-HEALS), conducted from 2002 to 2013, were analyzed. A total of 363,541 participants were enrolled in this retrospective cohort study. Data on socio-demographic characteristics and CAP-related variables were collected. Participants were divided into 4 groups according to CP severity. Cox proportional hazards regression was performed after adjusting for sociodemographic and related covariates. RESULTS A total of 363,541 participants were included in the analysis. The number of CAP cases in the index period was 14,838 (4.1%). Among the 4 groups, the mean age was significantly higher in the severe CP group. The incidence rates of severe and non-severe CP were 5.68 and 4.99, respectively (per 103 person-years). The hazard ratio for CAP was not significant in any of the models regardless of the presence or absence of CP. On stratification analysis by sex, smoking and Charlson comorbidity index, there were no significant differences between CAP and CP in any of the models. CONCLUSION The results of this study show that CP may not be a potential risk factor for CAP.

中文翻译：

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慢性牙周炎和社区获得性肺炎：一项基于人群的队列研究。

背景技术这项研究旨在根据国家健康保险服务数据库，根据韩国人群的CP严重性来确定慢性牙周炎（CP）与社区获得性肺炎（CAP）之间的关联。方法分析了2002年至2013年进行的国家健康保险服务-国家健康筛查队列（NHIS-HEALS）的数据。这项回顾性队列研究共纳入363,541名参与者。收集了有关社会人口学特征和CAP相关变量的数据。根据CP严重程度将参与者分为4组。在对社会人口统计学和相关协变量进行调整后，进行了Cox比例风险回归。结果共有363,541名参与者被纳入分析。在指数期内，CAP病例数为14,838（4。1％）。在这四个组中，重度CP组的平均年龄明显更高。重度和非重度CP的发生率分别为5.68和4.99（每103人年）。CAP的危险比在任何模型中均不显着，无论CP是否存在。通过性别，吸烟和查尔森合并症指数进行分层分析，在任何模型中，CAP和CP之间均无显着差异。结论这项研究的结果表明CP可能不是CAP的潜在危险因素。通过性别，吸烟和查尔森合并症指数进行分层分析，在任何模型中，CAP和CP之间均无显着差异。结论这项研究的结果表明CP可能不是CAP的潜在危险因素。通过性别，吸烟和查尔森合并症指数进行分层分析，在任何模型中，CAP和CP之间均无显着差异。结论这项研究的结果表明CP可能不是CAP的潜在危险因素。