BACKGROUND The aim of this systematic review is to determine the epidemiological and etiological profiles, the influential factors of the prehospital delay, thrombolysis management, the acute and 3-month mortality rate and the genetic aspect of ischemic stroke in Morocco. METHODS The present work is a systematic review that was conducted according to the recommendations of the "Preferred reporting items for systematic reviews and meta-analysis". We used Pubmed, Sciencedirect, Scopus, Clinicalkey, and Google scholar databases for the raking of the gray literature during the time frame 2009 and 2018. The protocol of the review was registered in the PROSPERO register (CRD42018115206). These studies were analyzed based on: Age, sex ratio, risk factors, etiological profile according to Trial of ORG classification 10,172 in Acute Stroke Treatment, prehospital delay average and its influential factors, thrombolyzed patients' proportion, acute and 3-month mortality and the genetic factors of ischemic stroke in Morocco. RESULTS Twenty-nine (n = 29) studies were selected. The average age ranged from 49 ± 15.2 to 67.3 ± 9.9 years old. Moreover, we reported male predominance within all ages in 13 studies. High blood pressure, diabetes, smoking and heart disease were the four identified main risk factors by the prementioned studies. Atherosclerosis and cardioembolic were the main described etiologies of cerebral ischemia, and the average prehospital time ranged from 26 to 61.9 h. The proportion of thrombolysed patients ranged from 1.8% to 2.9%, the mortality rate varied in the acute phase from 3 to 13%, and the 3-month mortality ranged from 4.3 to 32.5%. It is also important to highlight that most of these studies, which were conducted in hospital environment, have a reduced sample size and no confidence interval. CONCLUSIONS Ischemic stroke is affecting more likely the young population with male predominance. Moreover, the long prehospital delay and the low proportion of thrombolysed patients are alarming. This indicates the need to investigate in depth the key factors influencing the access to care for Moroccan patients in order to improve the management of this neurologic deficit in Morocco.

中文翻译：

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摩洛哥缺血性中风：系统评价。

背景技术本系统综述的目的是确定摩洛哥的流行病学和病因学特征，院前延迟，溶栓治疗，急性和3个月死亡率以及缺血性中风的遗传方面的影响因素。方法目前的工作是根据“系统评价和荟萃分析的首选报告项目”的建议进行的系统评价。我们使用Pubmed，Sciencedirect，Scopus，Clinicalkey和Google Scholar数据库在2009年和2018年的时间范围内搜查了灰色文献。该评价的协议已在PROSPERO寄存器（CRD42018115206）中进行了注册。根据ORG分类试验10，根据年龄，性别比，危险因素，病因资料对这些研究进行了分析，在摩洛哥，急性卒中治疗中的172名，院前平均延迟时间及其影响因素，溶栓患者的比例，急性和3个月死亡率以及缺血性卒中的遗传因素。结果选择了29项研究（n = 29）。平均年龄为49±15.2至67.3±9.9岁。此外，我们在13项研究中报告了所有年龄段的男性占主导地位。高血压，糖尿病，吸烟和心脏病是上述研究确定的四个主要危险因素。动脉粥样硬化和心脏栓塞是脑缺血的主要描述病因，院前平均时间为26至61.9 h。溶栓患者的比例为1.8％至2.9％，急性期的死亡率为3％至13％，三个月的死亡率为4.3％至32.5％。同样重要的是要强调指出，大多数在医院环境中进行的研究均减少了样本量，并且没有置信区间。结论缺血性中风更可能影响以男性为主的年轻人群。此外，院前延迟时间长和溶栓患者比例低令人担忧。这表明有必要深入研究影响摩洛哥患者获得医疗服务的关键因素，以改善摩洛哥对这种神经功能缺损的管理。长期的院前延迟和低比例的溶栓患者令人震惊。这表明有必要深入研究影响摩洛哥患者获得医疗服务的关键因素，以改善摩洛哥对这种神经功能缺损的管理。长期的院前延迟和低比例的溶栓患者令人震惊。这表明有必要深入研究影响摩洛哥患者就医的关键因素，以改善摩洛哥对这种神经功能缺损的管理。