Coumarin-3-formylpyrazoles have been synthesized and applied as 3-carbon synthons in reaction with 3-hydroxyoxindoles by using DABCO as the catalyst. A range of structurally diverse spiro-fused pentacyclic spirooxindoles, bearing a spirooxindole-γ-lactone and a 3,4-dihydrocoumarin substructure, could be smoothly obtained in good to excellent yields (up to 99%) with excellent diastereoselectivities (all cases >20 : 1 dr). The asymmetric version of this tandem reaction was preliminarily investigated by using chiral organocatalysts.

中文翻译：

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香豆素-3-甲酰基吡唑类化合物在环缩合中作为3碳合成子用于螺环稠合的五环螺氧并吲哚的合成。

合成了香豆素-3-甲酰基吡唑，并以DABCO为催化剂，将其作为3-碳合成子与3-羟基羟吲哚反应。可以平稳地获得一系列结构多样的螺旋稠合的五环螺旋螺环，它们带有螺氧吲哚-γ-内酯和3,4-二氢香豆素亚结构，具有良好的至优异的产率（高达99％）和非对映选择性（所有情况> 20） ：1个博士）。通过使用手性有机催化剂初步研究了该串联反应的不对称形式。