Biological samples such as tissues, blood and other body fluids, plants or seeds, prokaryotic and eukaryotic cells or isolated biomolecules as well as associated data are the essential raw material for research and development in medicine, biotechnology and agriculture. The collection, processing, preservation, and storage of these resources, in addition to provision of access, are key activities of biobanks or biological resource centres. Biobanks have to ensure proper quality of samples and data, ethical and legal compliance as well as transparent and efficient access procedures. In this context the review places special emphasis on pre-analytical procedures and international standards, which are essential to improving analytical data reliability and reproducibility, as well as on the increasing importance of data management. These requirements of biobanks are demonstrated using the example of pathogen-containing and microbiome biobanks, and refer to needs in cancer research and development.

中文翻译：

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生命科学和个性化医学生物库：标准化，生物安全，生物安全和数据管理的重要性。

生物样品，例如组织，血液和其他体液，植物或种子，原核和真核细胞或分离的生物分子以及相关数据，是医学，生物技术和农业研究与开发的重要原料。除了提供获取之外，这些资源的收集，处理，保存和存储是生物库或生物资源中心的关键活动。生物银行必须确保样本和数据的适当质量，合乎道德和法律的要求以及透明和有效的访问程序。在这种情况下，审查特别强调了分析前的程序和国际标准，这对于提高分析数据的可靠性和可重复性以及数据管理的重要性日益重要。