We report electron diffraction of pyrene nanoclusters embedded in superfluid helium droplets. Using a least-squares fitting procedure, we have been able to separate the contribution of helium from those of the pyrene nanoclusters and determine the most likely structures for dimers and trimers. We confirm that pyrene dimers form a parallel double-layer structure with an interlayer distance of 3.5 Å and suggest that pyrene trimers form a sandwich structure but that the molecular planes are not completely parallel. The relative contributions of the dimers and trimers are ∼6:1. This work is an extension of our effort of solving structures of biological molecules using serial single-molecule electron diffraction imaging. The success of electron diffraction from an all-light-atom sample embedded in helium droplets offers reassuring evidence of the feasibility of this approach.

中文翻译：

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嵌入超流氦液滴中的Nano纳米簇的电子衍射。

我们报告嵌入超流氦滴的pyr纳米簇的电子衍射。使用最小二乘拟合程序，我们已经能够将氦的贡献与the纳米簇的贡献分开，并确定最可能的二聚体和三聚体结构。我们证实pyr二聚体形成层间距离为3.5的平行双层结构，并暗示pyr三聚体形成夹心结构，但分子平面不完全平行。二聚体和三聚体的相对贡献约为6：1。这项工作是我们使用串行单分子电子衍射成像技术解决生物分子结构的努力的延伸。